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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Boston AIDS Survival Score (BASS): a multidimensional AIDS severity instrument.</title><author><name sortKey="Seage, G R" sort="Seage, G R" uniqKey="Seage G" first="G R" last="Seage">G R Seage</name></author><author><name sortKey="Gatsonis, C" sort="Gatsonis, C" uniqKey="Gatsonis C" first="C" last="Gatsonis">C. Gatsonis</name></author><author><name sortKey="Weissman, J S" sort="Weissman, J S" uniqKey="Weissman J" first="J S" last="Weissman">J S Weissman</name></author><author><name sortKey="Haas, J S" sort="Haas, J S" uniqKey="Haas J" first="J S" last="Haas">J S Haas</name></author><author><name sortKey="Cleary, P D" sort="Cleary, P D" uniqKey="Cleary P" first="P D" last="Cleary">P D Cleary</name></author><author><name sortKey="Fowler, F J" sort="Fowler, F J" uniqKey="Fowler F" first="F J" last="Fowler">F J Fowler</name></author><author><name sortKey="Massagli, M P" sort="Massagli, M P" uniqKey="Massagli M" first="M P" last="Massagli">M P Massagli</name></author><author><name sortKey="Stone, V E" sort="Stone, V E" uniqKey="Stone V" first="V E" last="Stone">V E Stone</name></author><author><name sortKey="Craven, D E" sort="Craven, D E" uniqKey="Craven D" first="D E" last="Craven">D E Craven</name></author><author><name sortKey="Makadon, H" sort="Makadon, H" uniqKey="Makadon H" first="H" last="Makadon">H. Makadon</name></author><author><name sortKey="Goldberg, J" sort="Goldberg, J" uniqKey="Goldberg J" first="J" last="Goldberg">J. Goldberg</name></author><author><name sortKey="Coltin, K" sort="Coltin, K" uniqKey="Coltin K" first="K" last="Coltin">K. Coltin</name></author><author><name sortKey="Levin, K S" sort="Levin, K S" uniqKey="Levin K" first="K S" last="Levin">K S Levin</name></author><author><name sortKey="Epstein, A M" sort="Epstein, A M" uniqKey="Epstein A" first="A M" last="Epstein">A M Epstein</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">9146433</idno><idno type="pmc">1380834</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1380834</idno><idno type="RBID">PMC:1380834</idno><date when="1997">1997</date><idno type="wicri:Area/Pmc/Corpus">001284</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001284</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Boston AIDS Survival Score (BASS): a multidimensional AIDS severity instrument.</title><author><name sortKey="Seage, G R" sort="Seage, G R" uniqKey="Seage G" first="G R" last="Seage">G R Seage</name></author><author><name sortKey="Gatsonis, C" sort="Gatsonis, C" uniqKey="Gatsonis C" first="C" last="Gatsonis">C. Gatsonis</name></author><author><name sortKey="Weissman, J S" sort="Weissman, J S" uniqKey="Weissman J" first="J S" last="Weissman">J S Weissman</name></author><author><name sortKey="Haas, J S" sort="Haas, J S" uniqKey="Haas J" first="J S" last="Haas">J S Haas</name></author><author><name sortKey="Cleary, P D" sort="Cleary, P D" uniqKey="Cleary P" first="P D" last="Cleary">P D Cleary</name></author><author><name sortKey="Fowler, F J" sort="Fowler, F J" uniqKey="Fowler F" first="F J" last="Fowler">F J Fowler</name></author><author><name sortKey="Massagli, M P" sort="Massagli, M P" uniqKey="Massagli M" first="M P" last="Massagli">M P Massagli</name></author><author><name sortKey="Stone, V E" sort="Stone, V E" uniqKey="Stone V" first="V E" last="Stone">V E Stone</name></author><author><name sortKey="Craven, D E" sort="Craven, D E" uniqKey="Craven D" first="D E" last="Craven">D E Craven</name></author><author><name sortKey="Makadon, H" sort="Makadon, H" uniqKey="Makadon H" first="H" last="Makadon">H. Makadon</name></author><author><name sortKey="Goldberg, J" sort="Goldberg, J" uniqKey="Goldberg J" first="J" last="Goldberg">J. Goldberg</name></author><author><name sortKey="Coltin, K" sort="Coltin, K" uniqKey="Coltin K" first="K" last="Coltin">K. Coltin</name></author><author><name sortKey="Levin, K S" sort="Levin, K S" uniqKey="Levin K" first="K S" last="Levin">K S Levin</name></author><author><name sortKey="Epstein, A M" sort="Epstein, A M" uniqKey="Epstein A" first="A M" last="Epstein">A M Epstein</name></author></analytic><series><title level="j">American Journal of Public Health</title><idno type="ISSN">0090-0036</idno><idno type="eISSN">1541-0048</idno><imprint><date when="1997">1997</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>OBJECTIVES: This study developed a new acquired immunodeficiency syndrome (AIDS) severity system by including diagnostic, physiological, functional, and sociodemographic factors predictive of survival. METHODS: Three-hundred five persons with AIDS in Boston were interviewed; their medical records were reviewed and vital status ascertained. RESULTS: Overall median (+/- SD) survival for the cohort from the first interview until death was 560 +/- 14.4 days. The best model for predicting survival, the Boston AIDS Survival Score, included the Justice score (stage 2 relative hazard [RH] = 1.25, 95% confidence interval [CI] = 0.80, 1.96; stage 3 RH = 1.76, 95% CI = 1.15, 2.70), a newly developed opportunistic disease score (Boston Opportunistic Disease Survival Score; stage 2 RH = 1.35, 95% CI = 0.90, 2.02; stage 3 RH = 2.10, 95% CI = 1.38, 3.18), and measures of activities of daily living (any intermediate limitations, RH = 1.84, 95% CI = 1.05, 3.21; any basic limitations, RH = 2.60, 95% CI = 1.44, 4.69). This model had substantially greater predictive power (R2 = .17, C statistic = .68) than the Justice score alone (R2 = .09, C statistic = .61). CONCLUSIONS: Incorporating data on clinically important events and functional status into a physiologically based system can improve the prediction of survival with AIDS.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Am J Public Health</journal-id><journal-title>American Journal of Public Health</journal-title><issn pub-type="ppub">0090-0036</issn><issn pub-type="epub">1541-0048</issn></journal-meta><article-meta><article-id pub-id-type="pmid">9146433</article-id><article-id pub-id-type="pmc">1380834</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>The Boston AIDS Survival Score (BASS): a multidimensional AIDS severity instrument.</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Seage</surname><given-names>G R</given-names><suffix>3rd</suffix></name></contrib><contrib contrib-type="author"><name><surname>Gatsonis</surname><given-names>C</given-names></name></contrib><contrib contrib-type="author"><name><surname>Weissman</surname><given-names>J S</given-names></name></contrib><contrib contrib-type="author"><name><surname>Haas</surname><given-names>J S</given-names></name></contrib><contrib contrib-type="author"><name><surname>Cleary</surname><given-names>P D</given-names></name></contrib><contrib contrib-type="author"><name><surname>Fowler</surname><given-names>F J</given-names></name></contrib><contrib contrib-type="author"><name><surname>Massagli</surname><given-names>M P</given-names></name></contrib><contrib contrib-type="author"><name><surname>Stone</surname><given-names>V E</given-names></name></contrib><contrib contrib-type="author"><name><surname>Craven</surname><given-names>D E</given-names></name></contrib><contrib contrib-type="author"><name><surname>Makadon</surname><given-names>H</given-names></name></contrib><contrib contrib-type="author"><name><surname>Goldberg</surname><given-names>J</given-names></name></contrib><contrib contrib-type="author"><name><surname>Coltin</surname><given-names>K</given-names></name></contrib><contrib contrib-type="author"><name><surname>Levin</surname><given-names>K S</given-names></name></contrib><contrib contrib-type="author"><name><surname>Epstein</surname><given-names>A M</given-names></name></contrib></contrib-group><aff>Institute for Urban Health Policy and Research, Boston Department of Health and Hospitals, Mass., USA.</aff><pub-date pub-type="ppub"><month>4</month><year>1997</year></pub-date><volume>87</volume><issue>4</issue><fpage>567</fpage><lpage>573</lpage><abstract><p>OBJECTIVES: This study developed a new acquired immunodeficiency syndrome (AIDS) severity system by including diagnostic, physiological, functional, and sociodemographic factors predictive of survival. METHODS: Three-hundred five persons with AIDS in Boston were interviewed; their medical records were reviewed and vital status ascertained. RESULTS: Overall median (+/- SD) survival for the cohort from the first interview until death was 560 +/- 14.4 days. The best model for predicting survival, the Boston AIDS Survival Score, included the Justice score (stage 2 relative hazard [RH] = 1.25, 95% confidence interval [CI] = 0.80, 1.96; stage 3 RH = 1.76, 95% CI = 1.15, 2.70), a newly developed opportunistic disease score (Boston Opportunistic Disease Survival Score; stage 2 RH = 1.35, 95% CI = 0.90, 2.02; stage 3 RH = 2.10, 95% CI = 1.38, 3.18), and measures of activities of daily living (any intermediate limitations, RH = 1.84, 95% CI = 1.05, 3.21; any basic limitations, RH = 2.60, 95% CI = 1.44, 4.69). This model had substantially greater predictive power (R2 = .17, C statistic = .68) than the Justice score alone (R2 = .09, C statistic = .61). CONCLUSIONS: Incorporating data on clinically important events and functional status into a physiologically based system can improve the prediction of survival with AIDS.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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