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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Boston AIDS Survival Score (BASS): a multidimensional AIDS severity instrument.</title>
<author><name sortKey="Seage, G R" sort="Seage, G R" uniqKey="Seage G" first="G R" last="Seage">G R Seage</name>
</author>
<author><name sortKey="Gatsonis, C" sort="Gatsonis, C" uniqKey="Gatsonis C" first="C" last="Gatsonis">C. Gatsonis</name>
</author>
<author><name sortKey="Weissman, J S" sort="Weissman, J S" uniqKey="Weissman J" first="J S" last="Weissman">J S Weissman</name>
</author>
<author><name sortKey="Haas, J S" sort="Haas, J S" uniqKey="Haas J" first="J S" last="Haas">J S Haas</name>
</author>
<author><name sortKey="Cleary, P D" sort="Cleary, P D" uniqKey="Cleary P" first="P D" last="Cleary">P D Cleary</name>
</author>
<author><name sortKey="Fowler, F J" sort="Fowler, F J" uniqKey="Fowler F" first="F J" last="Fowler">F J Fowler</name>
</author>
<author><name sortKey="Massagli, M P" sort="Massagli, M P" uniqKey="Massagli M" first="M P" last="Massagli">M P Massagli</name>
</author>
<author><name sortKey="Stone, V E" sort="Stone, V E" uniqKey="Stone V" first="V E" last="Stone">V E Stone</name>
</author>
<author><name sortKey="Craven, D E" sort="Craven, D E" uniqKey="Craven D" first="D E" last="Craven">D E Craven</name>
</author>
<author><name sortKey="Makadon, H" sort="Makadon, H" uniqKey="Makadon H" first="H" last="Makadon">H. Makadon</name>
</author>
<author><name sortKey="Goldberg, J" sort="Goldberg, J" uniqKey="Goldberg J" first="J" last="Goldberg">J. Goldberg</name>
</author>
<author><name sortKey="Coltin, K" sort="Coltin, K" uniqKey="Coltin K" first="K" last="Coltin">K. Coltin</name>
</author>
<author><name sortKey="Levin, K S" sort="Levin, K S" uniqKey="Levin K" first="K S" last="Levin">K S Levin</name>
</author>
<author><name sortKey="Epstein, A M" sort="Epstein, A M" uniqKey="Epstein A" first="A M" last="Epstein">A M Epstein</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">9146433</idno>
<idno type="pmc">1380834</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1380834</idno>
<idno type="RBID">PMC:1380834</idno>
<date when="1997">1997</date>
<idno type="wicri:Area/Pmc/Corpus">001284</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001284</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Boston AIDS Survival Score (BASS): a multidimensional AIDS severity instrument.</title>
<author><name sortKey="Seage, G R" sort="Seage, G R" uniqKey="Seage G" first="G R" last="Seage">G R Seage</name>
</author>
<author><name sortKey="Gatsonis, C" sort="Gatsonis, C" uniqKey="Gatsonis C" first="C" last="Gatsonis">C. Gatsonis</name>
</author>
<author><name sortKey="Weissman, J S" sort="Weissman, J S" uniqKey="Weissman J" first="J S" last="Weissman">J S Weissman</name>
</author>
<author><name sortKey="Haas, J S" sort="Haas, J S" uniqKey="Haas J" first="J S" last="Haas">J S Haas</name>
</author>
<author><name sortKey="Cleary, P D" sort="Cleary, P D" uniqKey="Cleary P" first="P D" last="Cleary">P D Cleary</name>
</author>
<author><name sortKey="Fowler, F J" sort="Fowler, F J" uniqKey="Fowler F" first="F J" last="Fowler">F J Fowler</name>
</author>
<author><name sortKey="Massagli, M P" sort="Massagli, M P" uniqKey="Massagli M" first="M P" last="Massagli">M P Massagli</name>
</author>
<author><name sortKey="Stone, V E" sort="Stone, V E" uniqKey="Stone V" first="V E" last="Stone">V E Stone</name>
</author>
<author><name sortKey="Craven, D E" sort="Craven, D E" uniqKey="Craven D" first="D E" last="Craven">D E Craven</name>
</author>
<author><name sortKey="Makadon, H" sort="Makadon, H" uniqKey="Makadon H" first="H" last="Makadon">H. Makadon</name>
</author>
<author><name sortKey="Goldberg, J" sort="Goldberg, J" uniqKey="Goldberg J" first="J" last="Goldberg">J. Goldberg</name>
</author>
<author><name sortKey="Coltin, K" sort="Coltin, K" uniqKey="Coltin K" first="K" last="Coltin">K. Coltin</name>
</author>
<author><name sortKey="Levin, K S" sort="Levin, K S" uniqKey="Levin K" first="K S" last="Levin">K S Levin</name>
</author>
<author><name sortKey="Epstein, A M" sort="Epstein, A M" uniqKey="Epstein A" first="A M" last="Epstein">A M Epstein</name>
</author>
</analytic>
<series><title level="j">American Journal of Public Health</title>
<idno type="ISSN">0090-0036</idno>
<idno type="eISSN">1541-0048</idno>
<imprint><date when="1997">1997</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>OBJECTIVES: This study developed a new acquired immunodeficiency syndrome (AIDS) severity system by including diagnostic, physiological, functional, and sociodemographic factors predictive of survival. METHODS: Three-hundred five persons with AIDS in Boston were interviewed; their medical records were reviewed and vital status ascertained. RESULTS: Overall median (+/- SD) survival for the cohort from the first interview until death was 560 +/- 14.4 days. The best model for predicting survival, the Boston AIDS Survival Score, included the Justice score (stage 2 relative hazard [RH] = 1.25, 95% confidence interval [CI] = 0.80, 1.96; stage 3 RH = 1.76, 95% CI = 1.15, 2.70), a newly developed opportunistic disease score (Boston Opportunistic Disease Survival Score; stage 2 RH = 1.35, 95% CI = 0.90, 2.02; stage 3 RH = 2.10, 95% CI = 1.38, 3.18), and measures of activities of daily living (any intermediate limitations, RH = 1.84, 95% CI = 1.05, 3.21; any basic limitations, RH = 2.60, 95% CI = 1.44, 4.69). This model had substantially greater predictive power (R2 = .17, C statistic = .68) than the Justice score alone (R2 = .09, C statistic = .61). CONCLUSIONS: Incorporating data on clinically important events and functional status into a physiologically based system can improve the prediction of survival with AIDS.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Am J Public Health</journal-id>
<journal-title>American Journal of Public Health</journal-title>
<issn pub-type="ppub">0090-0036</issn>
<issn pub-type="epub">1541-0048</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">9146433</article-id>
<article-id pub-id-type="pmc">1380834</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>The Boston AIDS Survival Score (BASS): a multidimensional AIDS severity instrument.</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Seage</surname>
<given-names>G R</given-names>
<suffix>3rd</suffix>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Gatsonis</surname>
<given-names>C</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Weissman</surname>
<given-names>J S</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Haas</surname>
<given-names>J S</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Cleary</surname>
<given-names>P D</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Fowler</surname>
<given-names>F J</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Massagli</surname>
<given-names>M P</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Stone</surname>
<given-names>V E</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Craven</surname>
<given-names>D E</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Makadon</surname>
<given-names>H</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Goldberg</surname>
<given-names>J</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Coltin</surname>
<given-names>K</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Levin</surname>
<given-names>K S</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Epstein</surname>
<given-names>A M</given-names>
</name>
</contrib>
</contrib-group>
<aff>Institute for Urban Health Policy and Research, Boston Department of Health and Hospitals, Mass., USA.</aff>
<pub-date pub-type="ppub"><month>4</month>
<year>1997</year>
</pub-date>
<volume>87</volume>
<issue>4</issue>
<fpage>567</fpage>
<lpage>573</lpage>
<abstract><p>OBJECTIVES: This study developed a new acquired immunodeficiency syndrome (AIDS) severity system by including diagnostic, physiological, functional, and sociodemographic factors predictive of survival. METHODS: Three-hundred five persons with AIDS in Boston were interviewed; their medical records were reviewed and vital status ascertained. RESULTS: Overall median (+/- SD) survival for the cohort from the first interview until death was 560 +/- 14.4 days. The best model for predicting survival, the Boston AIDS Survival Score, included the Justice score (stage 2 relative hazard [RH] = 1.25, 95% confidence interval [CI] = 0.80, 1.96; stage 3 RH = 1.76, 95% CI = 1.15, 2.70), a newly developed opportunistic disease score (Boston Opportunistic Disease Survival Score; stage 2 RH = 1.35, 95% CI = 0.90, 2.02; stage 3 RH = 2.10, 95% CI = 1.38, 3.18), and measures of activities of daily living (any intermediate limitations, RH = 1.84, 95% CI = 1.05, 3.21; any basic limitations, RH = 2.60, 95% CI = 1.44, 4.69). This model had substantially greater predictive power (R2 = .17, C statistic = .68) than the Justice score alone (R2 = .09, C statistic = .61). CONCLUSIONS: Incorporating data on clinically important events and functional status into a physiologically based system can improve the prediction of survival with AIDS.</p>
</abstract>
</article-meta>
</front>
</pmc>
</record>
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