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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Role of Adjuvant Hysterectomy After Radiotherapy in Cervical Cancer</title>
<author><name sortKey="Rema, P" sort="Rema, P" uniqKey="Rema P" first="P." last="Rema">P. Rema</name>
<affiliation><nlm:aff id="Aff1">Division of Surgical Oncology, Regional Cancer Centre, Trivandrum, Kerala India</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Suchetha, S" sort="Suchetha, S" uniqKey="Suchetha S" first="S." last="Suchetha">S. Suchetha</name>
<affiliation><nlm:aff id="Aff1">Division of Surgical Oncology, Regional Cancer Centre, Trivandrum, Kerala India</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kumar, Aswin" sort="Kumar, Aswin" uniqKey="Kumar A" first="Aswin" last="Kumar">Aswin Kumar</name>
<affiliation><nlm:aff id="Aff2">Division of Radiotherapy, Regional Cancer Centre, Trivandrum, Kerala India</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ahmed, Iqbal" sort="Ahmed, Iqbal" uniqKey="Ahmed I" first="Iqbal" last="Ahmed">Iqbal Ahmed</name>
<affiliation><nlm:aff id="Aff1">Division of Surgical Oncology, Regional Cancer Centre, Trivandrum, Kerala India</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">27011479</idno>
<idno type="pmc">4775553</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775553</idno>
<idno type="RBID">PMC:4775553</idno>
<idno type="doi">10.1007/s12262-014-1060-3</idno>
<date when="2014">2014</date>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Role of Adjuvant Hysterectomy After Radiotherapy in Cervical Cancer</title>
<author><name sortKey="Rema, P" sort="Rema, P" uniqKey="Rema P" first="P." last="Rema">P. Rema</name>
<affiliation><nlm:aff id="Aff1">Division of Surgical Oncology, Regional Cancer Centre, Trivandrum, Kerala India</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Suchetha, S" sort="Suchetha, S" uniqKey="Suchetha S" first="S." last="Suchetha">S. Suchetha</name>
<affiliation><nlm:aff id="Aff1">Division of Surgical Oncology, Regional Cancer Centre, Trivandrum, Kerala India</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kumar, Aswin" sort="Kumar, Aswin" uniqKey="Kumar A" first="Aswin" last="Kumar">Aswin Kumar</name>
<affiliation><nlm:aff id="Aff2">Division of Radiotherapy, Regional Cancer Centre, Trivandrum, Kerala India</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ahmed, Iqbal" sort="Ahmed, Iqbal" uniqKey="Ahmed I" first="Iqbal" last="Ahmed">Iqbal Ahmed</name>
<affiliation><nlm:aff id="Aff1">Division of Surgical Oncology, Regional Cancer Centre, Trivandrum, Kerala India</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">The Indian Journal of Surgery</title>
<idno type="ISSN">0972-2068</idno>
<idno type="eISSN">0973-9793</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
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<front><div type="abstract" xml:lang="en"><p>The aim of this study was to evaluate the morbidity and survival outcome following radical hysterectomy after chemoradiotherapy in the International Federation of Gynecology and Obstetrics (FIGO) stages IB–IIB cervical cancer patients in whom intracavitory brachytherapy was not feasible. We retrospectively reviewed the medical records of our patients who underwent adjuvant radical hysterectomy between January 2005 and December 2012. Post-operative complications were graded according to the grading system of Chassagne et al. (Radiother Oncol 26:195–202, <xref ref-type="bibr" rid="CR1">1993</xref>
). Survival analysis was done using Kaplan-Meir method. Between January 2005 and December 2012, 43 patients underwent type 2 radical hysterectomy after external beam radiotherapy and concurrent chemotherapy. The median age of the study group was 44 years (range 28–63 years). There were no perioperative deaths. In the early post-operative period, there were 45 complications in 29 patients of which three were of grade 3 severity. The most common post operative complications were urinary tract infections and lymphoedema. The median follow-up time was 29 months (range 9–68 months). The 5-year overall survival was 85.5 % and disease-free survival 82.1 %. This study shows that radical hysterectomy is feasible with good survival outcome and acceptable morbidity after chemoradiotherapy in cervical cancer patients.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Indian J Surg</journal-id>
<journal-id journal-id-type="iso-abbrev">Indian J Surg</journal-id>
<journal-title-group><journal-title>The Indian Journal of Surgery</journal-title>
</journal-title-group>
<issn pub-type="ppub">0972-2068</issn>
<issn pub-type="epub">0973-9793</issn>
<publisher><publisher-name>Springer India</publisher-name>
<publisher-loc>New Delhi</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">27011479</article-id>
<article-id pub-id-type="pmc">4775553</article-id>
<article-id pub-id-type="publisher-id">1060</article-id>
<article-id pub-id-type="doi">10.1007/s12262-014-1060-3</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>The Role of Adjuvant Hysterectomy After Radiotherapy in Cervical Cancer</article-title>
</title-group>
<contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Rema</surname>
<given-names>P.</given-names>
</name>
<address><email>drremaanil@gmail.com</email>
</address>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<contrib contrib-type="author"><name><surname>Suchetha</surname>
<given-names>S.</given-names>
</name>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kumar</surname>
<given-names>Aswin</given-names>
</name>
<xref ref-type="aff" rid="Aff2"></xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ahmed</surname>
<given-names>Iqbal</given-names>
</name>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<aff id="Aff1"><label></label>
Division of Surgical Oncology, Regional Cancer Centre, Trivandrum, Kerala India</aff>
<aff id="Aff2"><label></label>
Division of Radiotherapy, Regional Cancer Centre, Trivandrum, Kerala India</aff>
</contrib-group>
<pub-date pub-type="epub"><day>10</day>
<month>4</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="ppub"><month>12</month>
<year>2015</year>
</pub-date>
<volume>77</volume>
<issue>Suppl 3</issue>
<fpage>902</fpage>
<lpage>905</lpage>
<history><date date-type="received"><day>1</day>
<month>2</month>
<year>2014</year>
</date>
<date date-type="accepted"><day>27</day>
<month>3</month>
<year>2014</year>
</date>
</history>
<permissions><copyright-statement>© Association of Surgeons of India 2014</copyright-statement>
</permissions>
<abstract id="Abs1"><p>The aim of this study was to evaluate the morbidity and survival outcome following radical hysterectomy after chemoradiotherapy in the International Federation of Gynecology and Obstetrics (FIGO) stages IB–IIB cervical cancer patients in whom intracavitory brachytherapy was not feasible. We retrospectively reviewed the medical records of our patients who underwent adjuvant radical hysterectomy between January 2005 and December 2012. Post-operative complications were graded according to the grading system of Chassagne et al. (Radiother Oncol 26:195–202, <xref ref-type="bibr" rid="CR1">1993</xref>
). Survival analysis was done using Kaplan-Meir method. Between January 2005 and December 2012, 43 patients underwent type 2 radical hysterectomy after external beam radiotherapy and concurrent chemotherapy. The median age of the study group was 44 years (range 28–63 years). There were no perioperative deaths. In the early post-operative period, there were 45 complications in 29 patients of which three were of grade 3 severity. The most common post operative complications were urinary tract infections and lymphoedema. The median follow-up time was 29 months (range 9–68 months). The 5-year overall survival was 85.5 % and disease-free survival 82.1 %. This study shows that radical hysterectomy is feasible with good survival outcome and acceptable morbidity after chemoradiotherapy in cervical cancer patients.</p>
</abstract>
<kwd-group xml:lang="en"><title>Keywords</title>
<kwd>Cervical cancer</kwd>
<kwd>Adjuvant hysterectomy</kwd>
<kwd>Radical hysterectomy</kwd>
<kwd>Morbidity</kwd>
</kwd-group>
<custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name>
<meta-value>© Association of Surgeons of India 2015</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
</record>
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