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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Host immune cellular reactions in corneal neovascularization</title><author><name sortKey="Abdelfattah, Nizar S" sort="Abdelfattah, Nizar S" uniqKey="Abdelfattah N" first="Nizar S." last="Abdelfattah">Nizar S. Abdelfattah</name><affiliation><nlm:aff id="aff1"><addr-line>Doheny Eye Institute, University of California, Los Angeles, CA 90033, USA</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="aff2"><addr-line>Ophthalmology Department, David Geffen School of Medicine, University of California, Los Angeles, CA 90033, USA</addr-line></nlm:aff></affiliation></author><author><name sortKey="Amgad, Mohamed" sort="Amgad, Mohamed" uniqKey="Amgad M" first="Mohamed" last="Amgad">Mohamed Amgad</name><affiliation><nlm:aff id="aff3"><addr-line>Faculty of Medicine, Cairo University, Cairo 11956, Egypt</addr-line></nlm:aff></affiliation></author><author><name sortKey="Zayed, Amira A" sort="Zayed, Amira A" uniqKey="Zayed A" first="Amira A" last="Zayed">Amira A. Zayed</name><affiliation><nlm:aff id="aff4"><addr-line>Department of Surgery, Mayo Clinic, Rochester, Minnesota 55904, USA</addr-line></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27162740</idno><idno type="pmc">4853363</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853363</idno><idno type="RBID">PMC:4853363</idno><idno type="doi">10.18240/ijo.2016.04.25</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000865</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000865</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Host immune cellular reactions in corneal neovascularization</title><author><name sortKey="Abdelfattah, Nizar S" sort="Abdelfattah, Nizar S" uniqKey="Abdelfattah N" first="Nizar S." last="Abdelfattah">Nizar S. Abdelfattah</name><affiliation><nlm:aff id="aff1"><addr-line>Doheny Eye Institute, University of California, Los Angeles, CA 90033, USA</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="aff2"><addr-line>Ophthalmology Department, David Geffen School of Medicine, University of California, Los Angeles, CA 90033, USA</addr-line></nlm:aff></affiliation></author><author><name sortKey="Amgad, Mohamed" sort="Amgad, Mohamed" uniqKey="Amgad M" first="Mohamed" last="Amgad">Mohamed Amgad</name><affiliation><nlm:aff id="aff3"><addr-line>Faculty of Medicine, Cairo University, Cairo 11956, Egypt</addr-line></nlm:aff></affiliation></author><author><name sortKey="Zayed, Amira A" sort="Zayed, Amira A" uniqKey="Zayed A" first="Amira A" last="Zayed">Amira A. Zayed</name><affiliation><nlm:aff id="aff4"><addr-line>Department of Surgery, Mayo Clinic, Rochester, Minnesota 55904, USA</addr-line></nlm:aff></affiliation></author></analytic><series><title level="j">International Journal of Ophthalmology</title><idno type="ISSN">2222-3959</idno><idno type="eISSN">2227-4898</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Corneal neovascularization (CNV) is a global important cause of visual impairment. The immune mechanisms leading to corneal heme- and lymphangiogenesis have been extensively studied over the past years as more attempts were made to develop better prophylactic and therapeutic measures. This article aims to discuss immune cells of particular relevance to CNV, with a focus on macrophages, Th17 cells, dendritic cells and the underlying immunology of common pathologies involving neovascularization of the cornea. Hopefully, a thorough understanding of these topics would propel the efforts to halt the detrimental effects of CNV.</p></div></front></TEI><pmc article-type="review-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Int J Ophthalmol</journal-id><journal-id journal-id-type="iso-abbrev">Int J Ophthalmol</journal-id><journal-id journal-id-type="publisher-id">IJO</journal-id><journal-title-group><journal-title>International Journal of Ophthalmology</journal-title></journal-title-group><issn pub-type="ppub">2222-3959</issn><issn pub-type="epub">2227-4898</issn><publisher><publisher-name>International Journal of Ophthalmology Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27162740</article-id><article-id pub-id-type="pmc">4853363</article-id><article-id pub-id-type="publisher-id">ijo-09-04-625</article-id><article-id pub-id-type="doi">10.18240/ijo.2016.04.25</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Host immune cellular reactions in corneal neovascularization</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Abdelfattah</surname><given-names>Nizar S.</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Amgad</surname><given-names>Mohamed</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Zayed</surname><given-names>Amira A</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib></contrib-group><aff id="aff1"><label>1</label><addr-line>Doheny Eye Institute, University of California, Los Angeles, CA 90033, USA</addr-line></aff><aff id="aff2"><label>2</label><addr-line>Ophthalmology Department, David Geffen School of Medicine, University of California, Los Angeles, CA 90033, USA</addr-line></aff><aff id="aff3"><label>3</label><addr-line>Faculty of Medicine, Cairo University, Cairo 11956, Egypt</addr-line></aff><aff id="aff4"><label>4</label><addr-line>Department of Surgery, Mayo Clinic, Rochester, Minnesota 55904, USA</addr-line></aff><author-notes><corresp><bold>Correspondence to:</bold> Nizar S. Abdelfattah. 1355 San Pablo Street, Suite 100, Los Angeles, CA 90033, USA. <email>nizar@ucla.edu</email></corresp></author-notes><pub-date pub-type="epub"><day>18</day><month>4</month><year>2016</year></pub-date><pub-date pub-type="collection"><year>2016</year></pub-date><volume>9</volume><issue>4</issue><fpage>625</fpage><lpage>633</lpage><history><date date-type="received"><day>16</day><month>5</month><year>2015</year></date><date date-type="accepted"><day>29</day><month>6</month><year>2015</year></date></history><permissions><copyright-statement>International Journal of Ophthalmology Press</copyright-statement><copyright-year>2016</copyright-year></permissions><abstract><p>Corneal neovascularization (CNV) is a global important cause of visual impairment. The immune mechanisms leading to corneal heme- and lymphangiogenesis have been extensively studied over the past years as more attempts were made to develop better prophylactic and therapeutic measures. This article aims to discuss immune cells of particular relevance to CNV, with a focus on macrophages, Th17 cells, dendritic cells and the underlying immunology of common pathologies involving neovascularization of the cornea. Hopefully, a thorough understanding of these topics would propel the efforts to halt the detrimental effects of CNV.</p></abstract><kwd-group><kwd>corneal neovascularization</kwd><kwd>macrophage</kwd><kwd>Th17 cells</kwd><kwd>dendritic cells</kwd><kwd>herpes simplex keratitis</kwd><kwd>keratoplasty</kwd><kwd>angiogenesis</kwd><kwd>lymphangiogenesis</kwd><kwd>contact lenses</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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