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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Angiosarcoma of the adrenal gland with concurrent contralateral advanced renal cell carcinoma: A diagnostic and management dilemma</title>
<author><name sortKey="Gusenbauer, Kaela" sort="Gusenbauer, Kaela" uniqKey="Gusenbauer K" first="Kaela" last="Gusenbauer">Kaela Gusenbauer</name>
<affiliation><nlm:aff id="af1-cuaj-5-6-e302">Division of Urology, Department of Surgery, McMaster University, Hamilton, ON;</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ruzhynsky, Vladimir" sort="Ruzhynsky, Vladimir" uniqKey="Ruzhynsky V" first="Vladimir" last="Ruzhynsky">Vladimir Ruzhynsky</name>
<affiliation><nlm:aff id="af1-cuaj-5-6-e302">Division of Urology, Department of Surgery, McMaster University, Hamilton, ON;</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kak, Ipshita" sort="Kak, Ipshita" uniqKey="Kak I" first="Ipshita" last="Kak">Ipshita Kak</name>
<affiliation><nlm:aff id="af2-cuaj-5-6-e302">Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Adili, Anthony F" sort="Adili, Anthony F" uniqKey="Adili A" first="Anthony F." last="Adili">Anthony F. Adili</name>
<affiliation><nlm:aff id="af1-cuaj-5-6-e302">Division of Urology, Department of Surgery, McMaster University, Hamilton, ON;</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Giedraitis, Kyle" sort="Giedraitis, Kyle" uniqKey="Giedraitis K" first="Kyle" last="Giedraitis">Kyle Giedraitis</name>
<affiliation><nlm:aff id="af1-cuaj-5-6-e302">Division of Urology, Department of Surgery, McMaster University, Hamilton, ON;</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Popovic, Snezana" sort="Popovic, Snezana" uniqKey="Popovic S" first="Snezana" last="Popovic">Snezana Popovic</name>
<affiliation><nlm:aff id="af2-cuaj-5-6-e302">Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kapoor, Anil" sort="Kapoor, Anil" uniqKey="Kapoor A" first="Anil" last="Kapoor">Anil Kapoor</name>
<affiliation><nlm:aff id="af1-cuaj-5-6-e302">Division of Urology, Department of Surgery, McMaster University, Hamilton, ON;</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">26029301</idno>
<idno type="pmc">4439230</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439230</idno>
<idno type="RBID">PMC:4439230</idno>
<idno type="doi">10.5489/cuaj.2322</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">000154</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000154</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Angiosarcoma of the adrenal gland with concurrent contralateral advanced renal cell carcinoma: A diagnostic and management dilemma</title>
<author><name sortKey="Gusenbauer, Kaela" sort="Gusenbauer, Kaela" uniqKey="Gusenbauer K" first="Kaela" last="Gusenbauer">Kaela Gusenbauer</name>
<affiliation><nlm:aff id="af1-cuaj-5-6-e302">Division of Urology, Department of Surgery, McMaster University, Hamilton, ON;</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ruzhynsky, Vladimir" sort="Ruzhynsky, Vladimir" uniqKey="Ruzhynsky V" first="Vladimir" last="Ruzhynsky">Vladimir Ruzhynsky</name>
<affiliation><nlm:aff id="af1-cuaj-5-6-e302">Division of Urology, Department of Surgery, McMaster University, Hamilton, ON;</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kak, Ipshita" sort="Kak, Ipshita" uniqKey="Kak I" first="Ipshita" last="Kak">Ipshita Kak</name>
<affiliation><nlm:aff id="af2-cuaj-5-6-e302">Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Adili, Anthony F" sort="Adili, Anthony F" uniqKey="Adili A" first="Anthony F." last="Adili">Anthony F. Adili</name>
<affiliation><nlm:aff id="af1-cuaj-5-6-e302">Division of Urology, Department of Surgery, McMaster University, Hamilton, ON;</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Giedraitis, Kyle" sort="Giedraitis, Kyle" uniqKey="Giedraitis K" first="Kyle" last="Giedraitis">Kyle Giedraitis</name>
<affiliation><nlm:aff id="af1-cuaj-5-6-e302">Division of Urology, Department of Surgery, McMaster University, Hamilton, ON;</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Popovic, Snezana" sort="Popovic, Snezana" uniqKey="Popovic S" first="Snezana" last="Popovic">Snezana Popovic</name>
<affiliation><nlm:aff id="af2-cuaj-5-6-e302">Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kapoor, Anil" sort="Kapoor, Anil" uniqKey="Kapoor A" first="Anil" last="Kapoor">Anil Kapoor</name>
<affiliation><nlm:aff id="af1-cuaj-5-6-e302">Division of Urology, Department of Surgery, McMaster University, Hamilton, ON;</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Canadian Urological Association Journal</title>
<idno type="ISSN">1911-6470</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Angiosarcoma is a rare high-grade malignant neoplasm with poor clinical outcome and survival rates, occurring most commonly in the skin and soft tissue. It is composed of neoplastic cells that demonstrate endothelial differentiation. The diagnosis of angiosarcoma can be difficult due to its pathohistologic presentation as a poorly differentiated neoplasm with associated secondary changes. We report a case of angiosarcoma of the adrenal gland with concurrent contralateral renal cell carcinoma (RCC) and renal vein thrombus. The presumptive clinical diagnosis was metastatic renal cell carcinoma to the contralateral adrenal gland. Pathohistologic evaluation demonstrated massive hematoma associated with intravascular papillary endothelial hyperplasia (IPEH)-like features. We discuss the pathohistological features used to ascertain a diagnosis of angiosarcoma in the presence of IPEH-like changes and differentiate it from reactive vascular proliferation seen in IPEH (Masson’s tumour).</p>
</div>
</front>
</TEI>
<pmc article-type="case-report"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Can Urol Assoc J</journal-id>
<journal-id journal-id-type="iso-abbrev">Can Urol Assoc J</journal-id>
<journal-id journal-id-type="publisher-id">CUAJ</journal-id>
<journal-title-group><journal-title>Canadian Urological Association Journal</journal-title>
</journal-title-group>
<issn pub-type="ppub">1911-6470</issn>
<publisher><publisher-name>Canadian Medical Association</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">26029301</article-id>
<article-id pub-id-type="pmc">4439230</article-id>
<article-id pub-id-type="doi">10.5489/cuaj.2322</article-id>
<article-id pub-id-type="publisher-id">cuaj-5-6-e302</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject>
</subj-group>
</article-categories>
<title-group><article-title>Angiosarcoma of the adrenal gland with concurrent contralateral advanced renal cell carcinoma: A diagnostic and management dilemma</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Gusenbauer</surname>
<given-names>Kaela</given-names>
</name>
<xref ref-type="aff" rid="af1-cuaj-5-6-e302"><sup>*</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ruzhynsky</surname>
<given-names>Vladimir</given-names>
</name>
<degrees>MD, PhD</degrees>
<xref ref-type="aff" rid="af1-cuaj-5-6-e302"><sup>*</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kak</surname>
<given-names>Ipshita</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="af2-cuaj-5-6-e302"><sup>†</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Adili</surname>
<given-names>Anthony F.</given-names>
</name>
<degrees>MBBCh(C)</degrees>
<xref ref-type="aff" rid="af1-cuaj-5-6-e302"><sup>*</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Giedraitis</surname>
<given-names>Kyle</given-names>
</name>
<xref ref-type="aff" rid="af1-cuaj-5-6-e302"><sup>*</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Popovic</surname>
<given-names>Snezana</given-names>
</name>
<degrees>MD, PhD, MSc, FRCPC</degrees>
<xref ref-type="aff" rid="af2-cuaj-5-6-e302"><sup>†</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kapoor</surname>
<given-names>Anil</given-names>
</name>
<degrees>MD, FRCSC</degrees>
<xref ref-type="aff" rid="af1-cuaj-5-6-e302"><sup>*</sup>
</xref>
<xref ref-type="corresp" rid="c1-cuaj-5-6-e302"></xref>
</contrib>
<aff id="af1-cuaj-5-6-e302"><label>*</label>
Division of Urology, Department of Surgery, McMaster University, Hamilton, ON;</aff>
<aff id="af2-cuaj-5-6-e302"><label>†</label>
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON</aff>
</contrib-group>
<author-notes><corresp id="c1-cuaj-5-6-e302">Correspondence: Dr. Anil Kapoor, Professor of Surgery (Urology) McMaster University, 50 Charlton Ave E, Room G344, Hamilton ON L8N 4A6; <email>akapoor@mcmaster.ca</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><season>May-Jun</season>
<year>2015</year>
</pub-date>
<pub-date pub-type="epub"><day>13</day>
<month>5</month>
<year>2015</year>
</pub-date>
<volume>9</volume>
<issue>5-6</issue>
<fpage>E302</fpage>
<lpage>E305</lpage>
<permissions><copyright-statement>Copyright: © 2015 Canadian Urological Association or its licensors</copyright-statement>
<copyright-year>2015</copyright-year>
</permissions>
<abstract><p>Angiosarcoma is a rare high-grade malignant neoplasm with poor clinical outcome and survival rates, occurring most commonly in the skin and soft tissue. It is composed of neoplastic cells that demonstrate endothelial differentiation. The diagnosis of angiosarcoma can be difficult due to its pathohistologic presentation as a poorly differentiated neoplasm with associated secondary changes. We report a case of angiosarcoma of the adrenal gland with concurrent contralateral renal cell carcinoma (RCC) and renal vein thrombus. The presumptive clinical diagnosis was metastatic renal cell carcinoma to the contralateral adrenal gland. Pathohistologic evaluation demonstrated massive hematoma associated with intravascular papillary endothelial hyperplasia (IPEH)-like features. We discuss the pathohistological features used to ascertain a diagnosis of angiosarcoma in the presence of IPEH-like changes and differentiate it from reactive vascular proliferation seen in IPEH (Masson’s tumour).</p>
</abstract>
</article-meta>
</front>
</pmc>
</record>
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