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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Review of Chest Wall Tumors: A Diagnostic, Therapeutic, and Reconstructive Challenge</title>
<author><name sortKey="David, Elizabeth A" sort="David, Elizabeth A" uniqKey="David E" first="Elizabeth A." last="David">Elizabeth A. David</name>
<affiliation><nlm:aff id="a25016-1">Department of General Surgery, Georgetown University Hospital, Washington DC</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Marshall, M Blair" sort="Marshall, M Blair" uniqKey="Marshall M" first="M. Blair" last="Marshall">M. Blair Marshall</name>
<affiliation><nlm:aff id="a25016-2">Division of Thoracic Surgery, Georgetown University Hospital, Washington DC</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">22294939</idno>
<idno type="pmc">3140237</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140237</idno>
<idno type="RBID">PMC:3140237</idno>
<idno type="doi">10.1055/s-0031-1275167</idno>
<date when="2011">2011</date>
<idno type="wicri:Area/Pmc/Corpus">000067</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000067</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Review of Chest Wall Tumors: A Diagnostic, Therapeutic, and Reconstructive Challenge</title>
<author><name sortKey="David, Elizabeth A" sort="David, Elizabeth A" uniqKey="David E" first="Elizabeth A." last="David">Elizabeth A. David</name>
<affiliation><nlm:aff id="a25016-1">Department of General Surgery, Georgetown University Hospital, Washington DC</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Marshall, M Blair" sort="Marshall, M Blair" uniqKey="Marshall M" first="M. Blair" last="Marshall">M. Blair Marshall</name>
<affiliation><nlm:aff id="a25016-2">Division of Thoracic Surgery, Georgetown University Hospital, Washington DC</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Seminars in Plastic Surgery</title>
<idno type="ISSN">1535-2188</idno>
<idno type="eISSN">1536-0067</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
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<front><div type="abstract" xml:lang="en"><p>Chest wall tumors are a heterogeneous group of lesions that provide an interesting diagnostic and therapeutic challenge for surgeons. They make up less than 5% of thoracic malignancies and vary widely in pathology as they arise from all anatomic structures of the chest wall. In general, treatment is wide local excision, the margins for malignant disease are necessarily wider, and adjuvant radiation is typically given for those with positive margins. Chemotherapy is rarely effective. Local control is the most important prognostic factor. Disease-free survival for malignant disease is limited by positive margins; therefore full oncologic resection with 4-cm margins should be attempted. For small lesions, the resection and reconstruction is usually straightforward. For more advanced disease or those lesions that require significant functional loss, preoperative planning using a multidisciplinary approach, incorporating thoracic surgery, plastic surgery, neurosurgery, radiation medicine, oncology, and physical medicine and rehabilitation, may be essential.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Semin Plast Surg</journal-id>
<journal-title-group><journal-title>Seminars in Plastic Surgery</journal-title>
</journal-title-group>
<issn pub-type="ppub">1535-2188</issn>
<issn pub-type="epub">1536-0067</issn>
<publisher><publisher-name>Thieme Medical Publishers</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">22294939</article-id>
<article-id pub-id-type="pmc">3140237</article-id>
<article-id pub-id-type="doi">10.1055/s-0031-1275167</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Review of Chest Wall Tumors: A Diagnostic, Therapeutic, and Reconstructive Challenge</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>David</surname>
<given-names>Elizabeth A.</given-names>
</name>
<degrees>M.D.</degrees>
<xref ref-type="aff" rid="a25016-1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Marshall</surname>
<given-names>M. Blair</given-names>
</name>
<degrees>M.D.</degrees>
<xref ref-type="aff" rid="a25016-2">2</xref>
</contrib>
<aff id="a25016-1"><label>1</label>
Department of General Surgery, Georgetown University Hospital, Washington DC</aff>
<aff id="a25016-2"><label>2</label>
Division of Thoracic Surgery, Georgetown University Hospital, Washington DC</aff>
</contrib-group>
<author-notes><corresp>Address for correspondence and reprint requests: <institution>4th Floor PHC Building, 3800 Reservoir Road</institution>
<addr-line>Washington, DC 20008</addr-line>
<email>mbm5@gunet.georgetown.edu</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><month>2</month>
<year>2011</year>
</pub-date>
<volume>25</volume>
<issue>1</issue>
<fpage>16</fpage>
<lpage>24</lpage>
<permissions><copyright-statement>© Thieme Medical Publishers</copyright-statement>
</permissions>
<abstract><p>Chest wall tumors are a heterogeneous group of lesions that provide an interesting diagnostic and therapeutic challenge for surgeons. They make up less than 5% of thoracic malignancies and vary widely in pathology as they arise from all anatomic structures of the chest wall. In general, treatment is wide local excision, the margins for malignant disease are necessarily wider, and adjuvant radiation is typically given for those with positive margins. Chemotherapy is rarely effective. Local control is the most important prognostic factor. Disease-free survival for malignant disease is limited by positive margins; therefore full oncologic resection with 4-cm margins should be attempted. For small lesions, the resection and reconstruction is usually straightforward. For more advanced disease or those lesions that require significant functional loss, preoperative planning using a multidisciplinary approach, incorporating thoracic surgery, plastic surgery, neurosurgery, radiation medicine, oncology, and physical medicine and rehabilitation, may be essential.</p>
</abstract>
<kwd-group><kwd>Chest wall tumor</kwd>
<kwd>primary chest wall tumor</kwd>
<kwd>chest wall resection</kwd>
</kwd-group>
<custom-meta-group><custom-meta><meta-name>issue-editor</meta-name>
<meta-value>Guest Editors
Karen K. Evans, M.D.
Samir Mardini, M.D.
Phillip G. Arnold, M.D.
</meta-value>
</custom-meta>
<custom-meta><meta-name>issue-theme</meta-name>
<meta-value>Chest Wall Reconstruction</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
</record>
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