Cutaneous abnormalities in rheumatoid arthritis compared with non‐inflammatory rheumatic conditions
Identifieur interne : 003C90 ( Pmc/Checkpoint ); précédent : 003C89; suivant : 003C91Cutaneous abnormalities in rheumatoid arthritis compared with non‐inflammatory rheumatic conditions
Auteurs : K M J. Douglas ; E. Ladoyanni ; G J Treharne ; E D Hale ; N. Erb ; G D KitasSource :
- Annals of the Rheumatic Diseases [ 0003-4967 ] ; 2006.
Abstract
Cutaneous abnormalities are common in rheumatoid arthritis, but exact prevalence estimates are yet to be established. Some abnormalities may be independent and coincidental, whereas others may relate to rheumatoid arthritis or its treatment.
To determine the exact nature and point prevalence of cutaneous abnormalities in patients with rheumatoid arthritis compared with those in patients with non‐inflammatory rheumatic disease.
349 consecutive outpatients for rheumatology (205 with rheumatoid arthritis and 144 with non‐inflammatory rheumatic conditions) were examined for skin and nail signs by a dermatologist. Histories of rheumatology, dermatology, drugs and allergy were noted in detail.
Skin abnormalities were reported by more patients with rheumatoid arthritis (61%) than non‐inflammatory controls (47%). More patients with rheumatoid arthritis (39%) than controls (10%) attributed their skin abnormality to drugs. Cutaneous abnormalities observed by the dermatologist were also more common in patients with rheumatoid arthritis (76%) than in the group with non‐inflammatory disease (60%). Specifically, bruising, athlete's foot, scars, rheumatoid nodules and vasculitic lesions were more common in patients with rheumatoid arthritis than in controls. The presence of bruising was predicted only by current steroid use. The presence of any other specific cutaneous abnormalities was not predicted by any of the variables assessed. In the whole group, current steroid use and having rheumatoid arthritis were the only important predictors of having any cutaneous abnormality.
Self‐reported and observed cutaneous abnormalities are more common in patients with rheumatoid arthritis than in controls with non‐inflammatory disease. These include cutaneous abnormalities related to side effects of drugs or to rheumatoid arthritis itself and other abnormalities previously believed to be independent but which may be of clinical importance.
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DOI: 10.1136/ard.2005.048934
PubMed: 16476709
PubMed Central: 1798318
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Erb</name></author><author><name sortKey="Kitas, G D" sort="Kitas, G D" uniqKey="Kitas G" first="G D" last="Kitas">G D Kitas</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">16476709</idno><idno type="pmc">1798318</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1798318</idno><idno type="RBID">PMC:1798318</idno><idno type="doi">10.1136/ard.2005.048934</idno><date when="2006">2006</date><idno type="wicri:Area/Pmc/Corpus">001342</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001342</idno><idno type="wicri:Area/Pmc/Curation">001341</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001341</idno><idno type="wicri:Area/Pmc/Checkpoint">003C90</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">003C90</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Cutaneous abnormalities in rheumatoid arthritis compared with non‐inflammatory rheumatic conditions</title><author><name sortKey="Douglas, K M J" sort="Douglas, K M J" uniqKey="Douglas K" first="K M J" last="Douglas">K M J. Douglas</name></author><author><name sortKey="Ladoyanni, E" sort="Ladoyanni, E" uniqKey="Ladoyanni E" first="E" last="Ladoyanni">E. Ladoyanni</name></author><author><name sortKey="Treharne, G J" sort="Treharne, G J" uniqKey="Treharne G" first="G J" last="Treharne">G J Treharne</name></author><author><name sortKey="Hale, E D" sort="Hale, E D" uniqKey="Hale E" first="E D" last="Hale">E D Hale</name></author><author><name sortKey="Erb, N" sort="Erb, N" uniqKey="Erb N" first="N" last="Erb">N. Erb</name></author><author><name sortKey="Kitas, G D" sort="Kitas, G D" uniqKey="Kitas G" first="G D" last="Kitas">G D Kitas</name></author></analytic><series><title level="j">Annals of the Rheumatic Diseases</title><idno type="ISSN">0003-4967</idno><idno type="eISSN">1468-2060</idno><imprint><date when="2006">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>Cutaneous abnormalities are common in rheumatoid arthritis, but exact prevalence estimates are yet to be established. Some abnormalities may be independent and coincidental, whereas others may relate to rheumatoid arthritis or its treatment.</p></sec><sec><title>Objectives</title><p>To determine the exact nature and point prevalence of cutaneous abnormalities in patients with rheumatoid arthritis compared with those in patients with non‐inflammatory rheumatic disease.</p></sec><sec><title>Methods</title><p>349 consecutive outpatients for rheumatology (205 with rheumatoid arthritis and 144 with non‐inflammatory rheumatic conditions) were examined for skin and nail signs by a dermatologist. Histories of rheumatology, dermatology, drugs and allergy were noted in detail.</p></sec><sec><title>Results</title><p>Skin abnormalities were reported by more patients with rheumatoid arthritis (61%) than non‐inflammatory controls (47%). More patients with rheumatoid arthritis (39%) than controls (10%) attributed their skin abnormality to drugs. Cutaneous abnormalities observed by the dermatologist were also more common in patients with rheumatoid arthritis (76%) than in the group with non‐inflammatory disease (60%). Specifically, bruising, athlete's foot, scars, rheumatoid nodules and vasculitic lesions were more common in patients with rheumatoid arthritis than in controls. The presence of bruising was predicted only by current steroid use. The presence of any other specific cutaneous abnormalities was not predicted by any of the variables assessed. In the whole group, current steroid use and having rheumatoid arthritis were the only important predictors of having any cutaneous abnormality.</p></sec><sec><title>Conclusions</title><p>Self‐reported and observed cutaneous abnormalities are more common in patients with rheumatoid arthritis than in controls with non‐inflammatory disease. These include cutaneous abnormalities related to side effects of drugs or to rheumatoid arthritis itself and other abnormalities previously believed to be independent but which may be of clinical importance.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Ann Rheum Dis</journal-id><journal-title>Annals of the Rheumatic Diseases</journal-title><issn pub-type="ppub">0003-4967</issn><issn pub-type="epub">1468-2060</issn><publisher><publisher-name>BMJ Group</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">16476709</article-id><article-id pub-id-type="pmc">1798318</article-id><article-id pub-id-type="publisher-id">ar48934</article-id><article-id pub-id-type="doi">10.1136/ard.2005.048934</article-id><article-categories><subj-group subj-group-type="heading"><subject>Extended Report</subject></subj-group></article-categories><title-group><article-title>Cutaneous abnormalities in rheumatoid arthritis compared with non‐inflammatory rheumatic conditions</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Douglas</surname><given-names>K M J</given-names></name></contrib><contrib contrib-type="author"><name><surname>Ladoyanni</surname><given-names>E</given-names></name></contrib><contrib contrib-type="author"><name><surname>Treharne</surname><given-names>G J</given-names></name></contrib><contrib contrib-type="author"><name><surname>Hale</surname><given-names>E D</given-names></name></contrib><contrib contrib-type="author"><name><surname>Erb</surname><given-names>N</given-names></name></contrib><contrib contrib-type="author"><name><surname>Kitas</surname><given-names>G D</given-names></name></contrib></contrib-group><aff><bold>K M J Douglas</bold>,<bold>E D Hale</bold>,<bold>N Erb</bold>,<bold>G D Kitas</bold>, Department of Rheumatology, Dudley Group of Hospitals NHS Trust, Dudley, West Midlands, UK</aff><aff><bold>E Ladoyanni</bold>, Department of Dermatology, Dudley Group of Hospitals NHS Trust</aff><aff><bold>G J Treharne</bold>, School of Psychology, University of Birmingham, Birmingham, UK</aff><author-notes><corresp>Correspondence to: G D Kitas<break></break>Department of Rheumatology, Dudley Group of Hospitals NHS Trust, Esk House, Russells Hall Hospital, Dudley, West Midlands DY1 2HQ, UK;
GD.Kitas@dgoh.nhs.uk</corresp><fn><p>Copyright © 2006 BMJ Publishing Group Ltd & European League Against Rheumatism</p></fn></author-notes><pub-date pub-type="ppub"><month>10</month><year>2006</year></pub-date><pub-date pub-type="epub"><day>13</day><month>2</month><year>2006</year></pub-date><volume>65</volume><issue>10</issue><fpage>1341</fpage><lpage>1345</lpage><history><date date-type="accepted"><day>4</day><month>2</month><year>2006</year></date></history><permissions><copyright-statement>Copyright © 2006 BMJ Publishing Group Ltd & European League Against Rheumatism</copyright-statement></permissions><abstract><sec><title>Background</title><p>Cutaneous abnormalities are common in rheumatoid arthritis, but exact prevalence estimates are yet to be established. Some abnormalities may be independent and coincidental, whereas others may relate to rheumatoid arthritis or its treatment.</p></sec><sec><title>Objectives</title><p>To determine the exact nature and point prevalence of cutaneous abnormalities in patients with rheumatoid arthritis compared with those in patients with non‐inflammatory rheumatic disease.</p></sec><sec><title>Methods</title><p>349 consecutive outpatients for rheumatology (205 with rheumatoid arthritis and 144 with non‐inflammatory rheumatic conditions) were examined for skin and nail signs by a dermatologist. Histories of rheumatology, dermatology, drugs and allergy were noted in detail.</p></sec><sec><title>Results</title><p>Skin abnormalities were reported by more patients with rheumatoid arthritis (61%) than non‐inflammatory controls (47%). More patients with rheumatoid arthritis (39%) than controls (10%) attributed their skin abnormality to drugs. Cutaneous abnormalities observed by the dermatologist were also more common in patients with rheumatoid arthritis (76%) than in the group with non‐inflammatory disease (60%). Specifically, bruising, athlete's foot, scars, rheumatoid nodules and vasculitic lesions were more common in patients with rheumatoid arthritis than in controls. The presence of bruising was predicted only by current steroid use. The presence of any other specific cutaneous abnormalities was not predicted by any of the variables assessed. In the whole group, current steroid use and having rheumatoid arthritis were the only important predictors of having any cutaneous abnormality.</p></sec><sec><title>Conclusions</title><p>Self‐reported and observed cutaneous abnormalities are more common in patients with rheumatoid arthritis than in controls with non‐inflammatory disease. These include cutaneous abnormalities related to side effects of drugs or to rheumatoid arthritis itself and other abnormalities previously believed to be independent but which may be of clinical importance.</p></sec></abstract></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Douglas, K M J" sort="Douglas, K M J" uniqKey="Douglas K" first="K M J" last="Douglas">K M J. Douglas</name><name sortKey="Erb, N" sort="Erb, N" uniqKey="Erb N" first="N" last="Erb">N. Erb</name><name sortKey="Hale, E D" sort="Hale, E D" uniqKey="Hale E" first="E D" last="Hale">E D Hale</name><name sortKey="Kitas, G D" sort="Kitas, G D" uniqKey="Kitas G" first="G D" last="Kitas">G D Kitas</name><name sortKey="Ladoyanni, E" sort="Ladoyanni, E" uniqKey="Ladoyanni E" first="E" last="Ladoyanni">E. Ladoyanni</name><name sortKey="Treharne, G J" sort="Treharne, G J" uniqKey="Treharne G" first="G J" last="Treharne">G J Treharne</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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