Rick Factors Associated with Aspiration in Patients with Head and Neck Cancer
Identifieur interne : 002D59 ( Pmc/Checkpoint ); précédent : 002D58; suivant : 002D60Rick Factors Associated with Aspiration in Patients with Head and Neck Cancer
Auteurs : Soo Jin Jung [Corée du Sud] ; Deog Young Kim [Corée du Sud] ; So Young Joo [Corée du Sud]Source :
- Annals of Rehabilitation Medicine [ 2234-0645 ] ; 2011.
Abstract
To determine the major risk factors and abnormal videofluoroscopic swallowing study (VFSS) findings associated with aspiration in patients with head and neck cancer (HNC).
Risk factors associated with aspiration were investigated retrospectively in 241 patients with HNC using medical records and pre-recorded VFSS. Age, gender, lesion location and stage, treatment factors, and swallowing stage abnormalities were included.
Aspiration occurred in 50.2% of patients. A univariate analysis revealed that advanced age, increased duration from disease onset to VFSS, higher tumor stage, increased lymph node stage, increased American Joint Committee on Cancer (AJCC) stage, operation history, chemotherapy history, and radiotherapy history were significantly associated with aspiration (p<0.05). Among them, advanced age, increase AJCC stage, operation history, and chemotherapy history were significantly associated with aspiration in the multivariate analysis (p<0.05). Delayed swallowing reflex and reduced elevation of the larynx were significantly associated with aspiration in the multivariate analysis (p<0.05).
The major risk factors associated with aspiration in patients with HNC were advanced age, higher AJCC stage, operation history, and chemotherapy history. A VFSS to evaluate aspiration is needed in patients with NHC who have these risk factors. Delayed swallowing reflex and reduced elevation of the larynx were major abnormal findings associated with aspiration. Dysphagia rehabilitation should focus on these results.
Url:
DOI: 10.5535/arm.2011.35.6.781
PubMed: 22506206
PubMed Central: 3309370
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:3309370Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Rick Factors Associated with Aspiration in Patients with Head and Neck Cancer</title>
<author><name sortKey="Jung, Soo Jin" sort="Jung, Soo Jin" uniqKey="Jung S" first="Soo Jin" last="Jung">Soo Jin Jung</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752, Korea.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Corée du Sud</country>
<wicri:regionArea>Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kim, Deog Young" sort="Kim, Deog Young" uniqKey="Kim D" first="Deog Young" last="Kim">Deog Young Kim</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752, Korea.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Corée du Sud</country>
<wicri:regionArea>Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Joo, So Young" sort="Joo, So Young" uniqKey="Joo S" first="So Young" last="Joo">So Young Joo</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752, Korea.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Corée du Sud</country>
<wicri:regionArea>Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">22506206</idno>
<idno type="pmc">3309370</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309370</idno>
<idno type="RBID">PMC:3309370</idno>
<idno type="doi">10.5535/arm.2011.35.6.781</idno>
<date when="2011">2011</date>
<idno type="wicri:Area/Pmc/Corpus">003B14</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003B14</idno>
<idno type="wicri:Area/Pmc/Curation">003B13</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003B13</idno>
<idno type="wicri:Area/Pmc/Checkpoint">002D59</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002D59</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Rick Factors Associated with Aspiration in Patients with Head and Neck Cancer</title>
<author><name sortKey="Jung, Soo Jin" sort="Jung, Soo Jin" uniqKey="Jung S" first="Soo Jin" last="Jung">Soo Jin Jung</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752, Korea.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Corée du Sud</country>
<wicri:regionArea>Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kim, Deog Young" sort="Kim, Deog Young" uniqKey="Kim D" first="Deog Young" last="Kim">Deog Young Kim</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752, Korea.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Corée du Sud</country>
<wicri:regionArea>Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Joo, So Young" sort="Joo, So Young" uniqKey="Joo S" first="So Young" last="Joo">So Young Joo</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752, Korea.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Corée du Sud</country>
<wicri:regionArea>Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Annals of Rehabilitation Medicine</title>
<idno type="ISSN">2234-0645</idno>
<idno type="eISSN">2234-0653</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Objective</title>
<p>To determine the major risk factors and abnormal videofluoroscopic swallowing study (VFSS) findings associated with aspiration in patients with head and neck cancer (HNC).</p>
</sec>
<sec><title>Method</title>
<p>Risk factors associated with aspiration were investigated retrospectively in 241 patients with HNC using medical records and pre-recorded VFSS. Age, gender, lesion location and stage, treatment factors, and swallowing stage abnormalities were included.</p>
</sec>
<sec><title>Results</title>
<p>Aspiration occurred in 50.2% of patients. A univariate analysis revealed that advanced age, increased duration from disease onset to VFSS, higher tumor stage, increased lymph node stage, increased American Joint Committee on Cancer (AJCC) stage, operation history, chemotherapy history, and radiotherapy history were significantly associated with aspiration (p<0.05). Among them, advanced age, increase AJCC stage, operation history, and chemotherapy history were significantly associated with aspiration in the multivariate analysis (p<0.05). Delayed swallowing reflex and reduced elevation of the larynx were significantly associated with aspiration in the multivariate analysis (p<0.05).</p>
</sec>
<sec><title>Conclusion</title>
<p>The major risk factors associated with aspiration in patients with HNC were advanced age, higher AJCC stage, operation history, and chemotherapy history. A VFSS to evaluate aspiration is needed in patients with NHC who have these risk factors. Delayed swallowing reflex and reduced elevation of the larynx were major abnormal findings associated with aspiration. Dysphagia rehabilitation should focus on these results.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Nguyen, Np" uniqKey="Nguyen N">NP Nguyen</name>
</author>
<author><name sortKey="Frank, C" uniqKey="Frank C">C Frank</name>
</author>
<author><name sortKey="Moltz, Cc" uniqKey="Moltz C">CC Moltz</name>
</author>
<author><name sortKey="Vos, P" uniqKey="Vos P">P Vos</name>
</author>
<author><name sortKey="Smith, Hj" uniqKey="Smith H">HJ Smith</name>
</author>
<author><name sortKey="Bhamidipati, Pv" uniqKey="Bhamidipati P">PV Bhamidipati</name>
</author>
<author><name sortKey="Karlsson, U" uniqKey="Karlsson U">U Karlsson</name>
</author>
<author><name sortKey="Nguyen, Pd" uniqKey="Nguyen P">PD Nguyen</name>
</author>
<author><name sortKey="Alfieri, A" uniqKey="Alfieri A">A Alfieri</name>
</author>
<author><name sortKey="Nguyen, Lm" uniqKey="Nguyen L">LM Nguyen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nguyen, Np" uniqKey="Nguyen N">NP Nguyen</name>
</author>
<author><name sortKey="Moltz, Cc" uniqKey="Moltz C">CC Moltz</name>
</author>
<author><name sortKey="Frank, C" uniqKey="Frank C">C Frank</name>
</author>
<author><name sortKey="Vos, P" uniqKey="Vos P">P Vos</name>
</author>
<author><name sortKey="Smith, Hj" uniqKey="Smith H">HJ Smith</name>
</author>
<author><name sortKey="Karlsson, U" uniqKey="Karlsson U">U Karlsson</name>
</author>
<author><name sortKey="Dutta, S" uniqKey="Dutta S">S Dutta</name>
</author>
<author><name sortKey="Midyett, Fa" uniqKey="Midyett F">FA Midyett</name>
</author>
<author><name sortKey="Barloon, J" uniqKey="Barloon J">J Barloon</name>
</author>
<author><name sortKey="Sallah, S" uniqKey="Sallah S">S Sallah</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kotz, T" uniqKey="Kotz T">T Kotz</name>
</author>
<author><name sortKey="Costello, R" uniqKey="Costello R">R Costello</name>
</author>
<author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name>
</author>
<author><name sortKey="Posner, Mr" uniqKey="Posner M">MR Posner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Carrara De Angelis, E" uniqKey="Carrara De Angelis E">E Carrara-de Angelis</name>
</author>
<author><name sortKey="Feher, O" uniqKey="Feher O">O Feher</name>
</author>
<author><name sortKey="Barros, Ap" uniqKey="Barros A">AP Barros</name>
</author>
<author><name sortKey="Nishimoto, In" uniqKey="Nishimoto I">IN Nishimoto</name>
</author>
<author><name sortKey="Kowalski, Lp" uniqKey="Kowalski L">LP Kowalski</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Steiniger, Jr" uniqKey="Steiniger J">JR Steiniger</name>
</author>
<author><name sortKey="Parnes, Sm" uniqKey="Parnes S">SM Parnes</name>
</author>
<author><name sortKey="Gardner, Gm" uniqKey="Gardner G">GM Gardner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Eisbruch, A" uniqKey="Eisbruch A">A Eisbruch</name>
</author>
<author><name sortKey="Lyden, T" uniqKey="Lyden T">T Lyden</name>
</author>
<author><name sortKey="Bradford, Cr" uniqKey="Bradford C">CR Bradford</name>
</author>
<author><name sortKey="Dawson, La" uniqKey="Dawson L">LA Dawson</name>
</author>
<author><name sortKey="Haxer, Mj" uniqKey="Haxer M">MJ Haxer</name>
</author>
<author><name sortKey="Miller, Ae" uniqKey="Miller A">AE Miller</name>
</author>
<author><name sortKey="Teknos, Tn" uniqKey="Teknos T">TN Teknos</name>
</author>
<author><name sortKey="Chepeha, Db" uniqKey="Chepeha D">DB Chepeha</name>
</author>
<author><name sortKey="Hogikyan, Nd" uniqKey="Hogikyan N">ND Hogikyan</name>
</author>
<author><name sortKey="Terrell, Je" uniqKey="Terrell J">JE Terrell</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Langerman, A" uniqKey="Langerman A">A Langerman</name>
</author>
<author><name sortKey="Maccracken, E" uniqKey="Maccracken E">E Maccracken</name>
</author>
<author><name sortKey="Kasza, K" uniqKey="Kasza K">K Kasza</name>
</author>
<author><name sortKey="Haraf, Dj" uniqKey="Haraf D">DJ Haraf</name>
</author>
<author><name sortKey="Vokes, Ee" uniqKey="Vokes E">EE Vokes</name>
</author>
<author><name sortKey="Stenson, Km" uniqKey="Stenson K">KM Stenson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wu, Ch" uniqKey="Wu C">CH Wu</name>
</author>
<author><name sortKey="Hsiao, Ty" uniqKey="Hsiao T">TY Hsiao</name>
</author>
<author><name sortKey="Ko, Jy" uniqKey="Ko J">JY Ko</name>
</author>
<author><name sortKey="Hsu, Mm" uniqKey="Hsu M">MM Hsu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hughes, Pj" uniqKey="Hughes P">PJ Hughes</name>
</author>
<author><name sortKey="Scott, Pm" uniqKey="Scott P">PM Scott</name>
</author>
<author><name sortKey="Kew, J" uniqKey="Kew J">J Kew</name>
</author>
<author><name sortKey="Cheung, Dm" uniqKey="Cheung D">DM Cheung</name>
</author>
<author><name sortKey="Leung, Sf" uniqKey="Leung S">SF Leung</name>
</author>
<author><name sortKey="Ahuja, At" uniqKey="Ahuja A">AT Ahuja</name>
</author>
<author><name sortKey="Van Hasselt, Ca" uniqKey="Van Hasselt C">CA van Hasselt</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nguyen, Np" uniqKey="Nguyen N">NP Nguyen</name>
</author>
<author><name sortKey="Moltz, Cc" uniqKey="Moltz C">CC Moltz</name>
</author>
<author><name sortKey="Frank, C" uniqKey="Frank C">C Frank</name>
</author>
<author><name sortKey="Vos, P" uniqKey="Vos P">P Vos</name>
</author>
<author><name sortKey="Smith, Hj" uniqKey="Smith H">HJ Smith</name>
</author>
<author><name sortKey="Nguyen, Pd" uniqKey="Nguyen P">PD Nguyen</name>
</author>
<author><name sortKey="Nguyen, Lm" uniqKey="Nguyen L">LM Nguyen</name>
</author>
<author><name sortKey="Dutta, S" uniqKey="Dutta S">S Dutta</name>
</author>
<author><name sortKey="Lemanski, C" uniqKey="Lemanski C">C Lemanski</name>
</author>
<author><name sortKey="Sallah, S" uniqKey="Sallah S">S Sallah</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bernal Sprekelsen, M" uniqKey="Bernal Sprekelsen M">M Bernal-Sprekelsen</name>
</author>
<author><name sortKey="Vilaseca Gonzalez, I" uniqKey="Vilaseca Gonzalez I">I Vilaseca-Gonzalez</name>
</author>
<author><name sortKey="Blanch Alejandro, Jl" uniqKey="Blanch Alejandro J">JL Blanch-Alejandro</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lazarus, Cl" uniqKey="Lazarus C">CL Lazarus</name>
</author>
<author><name sortKey="Logemann, Ja" uniqKey="Logemann J">JA Logemann</name>
</author>
<author><name sortKey="Pauloski, Br" uniqKey="Pauloski B">BR Pauloski</name>
</author>
<author><name sortKey="Colangelo, La" uniqKey="Colangelo L">LA Colangelo</name>
</author>
<author><name sortKey="Kahrilas, Pj" uniqKey="Kahrilas P">PJ Kahrilas</name>
</author>
<author><name sortKey="Mittal, Bb" uniqKey="Mittal B">BB Mittal</name>
</author>
<author><name sortKey="Pierce, M" uniqKey="Pierce M">M Pierce</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stenson, Km" uniqKey="Stenson K">KM Stenson</name>
</author>
<author><name sortKey="Maccracken, E" uniqKey="Maccracken E">E MacCracken</name>
</author>
<author><name sortKey="List, M" uniqKey="List M">M List</name>
</author>
<author><name sortKey="Haraf, Dj" uniqKey="Haraf D">DJ Haraf</name>
</author>
<author><name sortKey="Brockstein, B" uniqKey="Brockstein B">B Brockstein</name>
</author>
<author><name sortKey="Weichselbaum, R" uniqKey="Weichselbaum R">R Weichselbaum</name>
</author>
<author><name sortKey="Vokes, Ee" uniqKey="Vokes E">EE Vokes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Humphreys, B" uniqKey="Humphreys B">B Humphreys</name>
</author>
<author><name sortKey="Mathog, R" uniqKey="Mathog R">R Mathog</name>
</author>
<author><name sortKey="Rosen, R" uniqKey="Rosen R">R Rosen</name>
</author>
<author><name sortKey="Miller, P" uniqKey="Miller P">P Miller</name>
</author>
<author><name sortKey="Muz, J" uniqKey="Muz J">J Muz</name>
</author>
<author><name sortKey="Nelson, R" uniqKey="Nelson R">R Nelson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Karnell, M" uniqKey="Karnell M">M Karnell</name>
</author>
<author><name sortKey="Maccracken, E" uniqKey="Maccracken E">E Maccracken</name>
</author>
<author><name sortKey="Moran, W" uniqKey="Moran W">W Moran</name>
</author>
<author><name sortKey="Vokes, E" uniqKey="Vokes E">E Vokes</name>
</author>
<author><name sortKey="Haraf, D" uniqKey="Haraf D">D Haraf</name>
</author>
<author><name sortKey="Panje, W" uniqKey="Panje W">W Panje</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Edge, Sb" uniqKey="Edge S">SB Edge</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Pannunzio, Tg" uniqKey="Pannunzio T">TG Pannunzio</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Starmer, H" uniqKey="Starmer H">H Starmer</name>
</author>
<author><name sortKey="Gourin, C" uniqKey="Gourin C">C Gourin</name>
</author>
<author><name sortKey="Lua, Ll" uniqKey="Lua L">LL Lua</name>
</author>
<author><name sortKey="Burkhead, L" uniqKey="Burkhead L">L Burkhead</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Patterson, Jm" uniqKey="Patterson J">JM Patterson</name>
</author>
<author><name sortKey="Hildreth, A" uniqKey="Hildreth A">A Hildreth</name>
</author>
<author><name sortKey="Mccoll, E" uniqKey="Mccoll E">E McColl</name>
</author>
<author><name sortKey="Carding, Pn" uniqKey="Carding P">PN Carding</name>
</author>
<author><name sortKey="Hamilton, D" uniqKey="Hamilton D">D Hamilton</name>
</author>
<author><name sortKey="Wilson, Ja" uniqKey="Wilson J">JA Wilson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Caudell, Jj" uniqKey="Caudell J">JJ Caudell</name>
</author>
<author><name sortKey="Schaner, Pe" uniqKey="Schaner P">PE Schaner</name>
</author>
<author><name sortKey="Meredith, Rf" uniqKey="Meredith R">RF Meredith</name>
</author>
<author><name sortKey="Locher, Jl" uniqKey="Locher J">JL Locher</name>
</author>
<author><name sortKey="Nabell, Lm" uniqKey="Nabell L">LM Nabell</name>
</author>
<author><name sortKey="Carroll, Wr" uniqKey="Carroll W">WR Carroll</name>
</author>
<author><name sortKey="Magnuson, Js" uniqKey="Magnuson J">JS Magnuson</name>
</author>
<author><name sortKey="Spencer, Sa" uniqKey="Spencer S">SA Spencer</name>
</author>
<author><name sortKey="Bonner, Ja" uniqKey="Bonner J">JA Bonner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Logemann, Ja" uniqKey="Logemann J">JA Logemann</name>
</author>
<author><name sortKey="Rademaker, Aw" uniqKey="Rademaker A">AW Rademaker</name>
</author>
<author><name sortKey="Pauloski, Br" uniqKey="Pauloski B">BR Pauloski</name>
</author>
<author><name sortKey="Pauloski, Br" uniqKey="Pauloski B">BR Pauloski</name>
</author>
<author><name sortKey="Lazarus, Cl" uniqKey="Lazarus C">CL Lazarus</name>
</author>
<author><name sortKey="Mittal, Bb" uniqKey="Mittal B">BB Mittal</name>
</author>
<author><name sortKey="Brockstein, B" uniqKey="Brockstein B">B Brockstein</name>
</author>
<author><name sortKey="Maccracken, E" uniqKey="Maccracken E">E Maccracken</name>
</author>
<author><name sortKey="Haraf, Dj" uniqKey="Haraf D">DJ Haraf</name>
</author>
<author><name sortKey="Vokes, Ee" uniqKey="Vokes E">EE Vokes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Smith, Rv" uniqKey="Smith R">RV Smith</name>
</author>
<author><name sortKey="Kotz, T" uniqKey="Kotz T">T Kotz</name>
</author>
<author><name sortKey="Beitler, Jj" uniqKey="Beitler J">JJ Beitler</name>
</author>
<author><name sortKey="Wadler, S" uniqKey="Wadler S">S Wadler</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kikawada, M" uniqKey="Kikawada M">M Kikawada</name>
</author>
<author><name sortKey="Iwamoto, T" uniqKey="Iwamoto T">T Iwamoto</name>
</author>
<author><name sortKey="Takasaki, M" uniqKey="Takasaki M">M Takasaki</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bloem, Br" uniqKey="Bloem B">BR Bloem</name>
</author>
<author><name sortKey="Lagaay, Am" uniqKey="Lagaay A">AM Lagaay</name>
</author>
<author><name sortKey="Van Beek, W" uniqKey="Van Beek W">W van Beek</name>
</author>
<author><name sortKey="Haan, J" uniqKey="Haan J">J Haan</name>
</author>
<author><name sortKey="Roos, Ra" uniqKey="Roos R">RA Roos</name>
</author>
<author><name sortKey="Wintzen, Ar" uniqKey="Wintzen A">AR Wintzen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Logemann, Ja" uniqKey="Logemann J">JA Logemann</name>
</author>
<author><name sortKey="Pauloski, Br" uniqKey="Pauloski B">BR Pauloski</name>
</author>
<author><name sortKey="Rademaker, Aw" uniqKey="Rademaker A">AW Rademaker</name>
</author>
<author><name sortKey="Lazarus, Cl" uniqKey="Lazarus C">CL Lazarus</name>
</author>
<author><name sortKey="Gaziano, J" uniqKey="Gaziano J">J Gaziano</name>
</author>
<author><name sortKey="Stachowiak, L" uniqKey="Stachowiak L">L Stachowiak</name>
</author>
<author><name sortKey="Newman, L" uniqKey="Newman L">L Newman</name>
</author>
<author><name sortKey="Maccracken, E" uniqKey="Maccracken E">E MacCracken</name>
</author>
<author><name sortKey="Santa, D" uniqKey="Santa D">D Santa</name>
</author>
<author><name sortKey="Mittal, B" uniqKey="Mittal B">B Mittal</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Campbell, Bh" uniqKey="Campbell B">BH Campbell</name>
</author>
<author><name sortKey="Spinelli, K" uniqKey="Spinelli K">K Spinelli</name>
</author>
<author><name sortKey="Marbella, Am" uniqKey="Marbella A">AM Marbella</name>
</author>
<author><name sortKey="Myers, Kb" uniqKey="Myers K">KB Myers</name>
</author>
<author><name sortKey="Kuhn, Jc" uniqKey="Kuhn J">JC Kuhn</name>
</author>
<author><name sortKey="Layde, Pm" uniqKey="Layde P">PM Layde</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chapuy, Ci" uniqKey="Chapuy C">CI Chapuy</name>
</author>
<author><name sortKey="Annino, Dj" uniqKey="Annino D">DJ Annino</name>
</author>
<author><name sortKey="Snavely, A" uniqKey="Snavely A">A Snavely</name>
</author>
<author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name>
</author>
<author><name sortKey="Tishler, Rb" uniqKey="Tishler R">RB Tishler</name>
</author>
<author><name sortKey="Norris, Cm" uniqKey="Norris C">CM Norris</name>
</author>
<author><name sortKey="Haddad, Ri" uniqKey="Haddad R">RI Haddad</name>
</author>
<author><name sortKey="Goguen, La" uniqKey="Goguen L">LA Goguen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nguyen, Np" uniqKey="Nguyen N">NP Nguyen</name>
</author>
<author><name sortKey="Frank, C" uniqKey="Frank C">C Frank</name>
</author>
<author><name sortKey="Moltz, Cc" uniqKey="Moltz C">CC Moltz</name>
</author>
<author><name sortKey="Vos, P" uniqKey="Vos P">P Vos</name>
</author>
<author><name sortKey="Smith, Hj" uniqKey="Smith H">HJ Smith</name>
</author>
<author><name sortKey="Nguyen, Pd" uniqKey="Nguyen P">PD Nguyen</name>
</author>
<author><name sortKey="Martinez, T" uniqKey="Martinez T">T Martinez</name>
</author>
<author><name sortKey="Karlsson, U" uniqKey="Karlsson U">U Karlsson</name>
</author>
<author><name sortKey="Dutta, S" uniqKey="Dutta S">S Dutta</name>
</author>
<author><name sortKey="Lemanski, C" uniqKey="Lemanski C">C Lemanski</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Weber, Rs" uniqKey="Weber R">RS Weber</name>
</author>
<author><name sortKey="Ohlms, L" uniqKey="Ohlms L">L Ohlms</name>
</author>
<author><name sortKey="Bowman, J" uniqKey="Bowman J">J Bowman</name>
</author>
<author><name sortKey="Jacob, R" uniqKey="Jacob R">R Jacob</name>
</author>
<author><name sortKey="Goepfert, H" uniqKey="Goepfert H">H Goepfert</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mcconnel, Fm" uniqKey="Mcconnel F">FM McConnel</name>
</author>
<author><name sortKey="Mendelsohn, Ms" uniqKey="Mendelsohn M">MS Mendelsohn</name>
</author>
<author><name sortKey="Logemann, Ja" uniqKey="Logemann J">JA Logemann</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kronenberger, Mb" uniqKey="Kronenberger M">MB Kronenberger</name>
</author>
<author><name sortKey="Meyers, Ad" uniqKey="Meyers A">AD Meyers</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lango, Mn" uniqKey="Lango M">MN Lango</name>
</author>
<author><name sortKey="Egleston, B" uniqKey="Egleston B">B Egleston</name>
</author>
<author><name sortKey="Ende, K" uniqKey="Ende K">K Ende</name>
</author>
<author><name sortKey="Feigenberg, S" uniqKey="Feigenberg S">S Feigenberg</name>
</author>
<author><name sortKey="D Ambrosio, Dj" uniqKey="D Ambrosio D">DJ D'Ambrosio</name>
</author>
<author><name sortKey="Cohen, Rb" uniqKey="Cohen R">RB Cohen</name>
</author>
<author><name sortKey="Ahmad, S" uniqKey="Ahmad S">S Ahmad</name>
</author>
<author><name sortKey="Nicolaou, N" uniqKey="Nicolaou N">N Nicolaou</name>
</author>
<author><name sortKey="Ridge, Ja" uniqKey="Ridge J">JA Ridge</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nguyen, Np" uniqKey="Nguyen N">NP Nguyen</name>
</author>
<author><name sortKey="Moltz, Cc" uniqKey="Moltz C">CC Moltz</name>
</author>
<author><name sortKey="Frank, C" uniqKey="Frank C">C Frank</name>
</author>
<author><name sortKey="Karlsson, U" uniqKey="Karlsson U">U Karlsson</name>
</author>
<author><name sortKey="Nguyen, Pd" uniqKey="Nguyen P">PD Nguyen</name>
</author>
<author><name sortKey="Vos, P" uniqKey="Vos P">P Vos</name>
</author>
<author><name sortKey="Smith, Hj" uniqKey="Smith H">HJ Smith</name>
</author>
<author><name sortKey="Dutta, S" uniqKey="Dutta S">S Dutta</name>
</author>
<author><name sortKey="Nguyen, Lm" uniqKey="Nguyen L">LM Nguyen</name>
</author>
<author><name sortKey="Lemanski, C" uniqKey="Lemanski C">C Lemanski</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gaziano, Je" uniqKey="Gaziano J">JE Gaziano</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Pauloski, Br" uniqKey="Pauloski B">BR Pauloski</name>
</author>
<author><name sortKey="Logemann, Ja" uniqKey="Logemann J">JA Logemann</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wu, Ch" uniqKey="Wu C">CH Wu</name>
</author>
<author><name sortKey="Hsiao, Ty" uniqKey="Hsiao T">TY Hsiao</name>
</author>
<author><name sortKey="Ko, Jy" uniqKey="Ko J">JY Ko</name>
</author>
<author><name sortKey="Hsu, Mm" uniqKey="Hsu M">MM Hsu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Galli, J" uniqKey="Galli J">J Galli</name>
</author>
<author><name sortKey="Valenza, V" uniqKey="Valenza V">V Valenza</name>
</author>
<author><name sortKey="D Alatri, L" uniqKey="D Alatri L">L D'Alatri</name>
</author>
<author><name sortKey="Reale, F" uniqKey="Reale F">F Reale</name>
</author>
<author><name sortKey="Gajate, As" uniqKey="Gajate A">AS Gajate</name>
</author>
<author><name sortKey="Di Girolamo, S" uniqKey="Di Girolamo S">S Di Girolamo</name>
</author>
<author><name sortKey="Paludetti, G" uniqKey="Paludetti G">G Paludetti</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Logemann, Ja" uniqKey="Logemann J">JA Logemann</name>
</author>
<author><name sortKey="Bytell, De" uniqKey="Bytell D">DE Bytell</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Ann Rehabil Med</journal-id>
<journal-id journal-id-type="iso-abbrev">Ann Rehabil Med</journal-id>
<journal-id journal-id-type="publisher-id">ARM</journal-id>
<journal-title-group><journal-title>Annals of Rehabilitation Medicine</journal-title>
</journal-title-group>
<issn pub-type="ppub">2234-0645</issn>
<issn pub-type="epub">2234-0653</issn>
<publisher><publisher-name>Korean Academy of Rehabilitation Medicine</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">22506206</article-id>
<article-id pub-id-type="pmc">3309370</article-id>
<article-id pub-id-type="doi">10.5535/arm.2011.35.6.781</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Rick Factors Associated with Aspiration in Patients with Head and Neck Cancer</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Jung</surname>
<given-names>Soo Jin</given-names>
</name>
<degrees>M.D.</degrees>
<xref ref-type="aff" rid="A1"></xref>
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Kim</surname>
<given-names>Deog Young</given-names>
</name>
<degrees>M.D.</degrees>
<degrees>Ph.D.</degrees>
<xref ref-type="aff" rid="A1"></xref>
</contrib>
<contrib contrib-type="author"><name><surname>Joo</surname>
<given-names>So Young</given-names>
</name>
<degrees>M.D.</degrees>
<xref ref-type="aff" rid="A1"></xref>
</contrib>
</contrib-group>
<aff id="A1">Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752, Korea.</aff>
<author-notes><corresp>Corresponding author: Deog Young Kim. Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, 134, Shinchon-dong, Seodaemun-gu, Seoul 120-752, Korea. Tel: +82-2-2228-3710, Fax: +82-2-363-2795, <email>kimdy@yuhs.ac</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><month>12</month>
<year>2011</year>
</pub-date>
<pub-date pub-type="epub"><day>30</day>
<month>12</month>
<year>2011</year>
</pub-date>
<volume>35</volume>
<issue>6</issue>
<fpage>781</fpage>
<lpage>790</lpage>
<history><date date-type="received"><day>16</day>
<month>8</month>
<year>2011</year>
</date>
<date date-type="accepted"><day>05</day>
<month>10</month>
<year>2011</year>
</date>
</history>
<permissions><copyright-statement>Copyright © 2011 by Korean Academy of Rehabilitation Medicine</copyright-statement>
<copyright-year>2011</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc/3.0"><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/3.0">http://creativecommons.org/licenses/by-nc/3.0</ext-link>
) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract><sec><title>Objective</title>
<p>To determine the major risk factors and abnormal videofluoroscopic swallowing study (VFSS) findings associated with aspiration in patients with head and neck cancer (HNC).</p>
</sec>
<sec><title>Method</title>
<p>Risk factors associated with aspiration were investigated retrospectively in 241 patients with HNC using medical records and pre-recorded VFSS. Age, gender, lesion location and stage, treatment factors, and swallowing stage abnormalities were included.</p>
</sec>
<sec><title>Results</title>
<p>Aspiration occurred in 50.2% of patients. A univariate analysis revealed that advanced age, increased duration from disease onset to VFSS, higher tumor stage, increased lymph node stage, increased American Joint Committee on Cancer (AJCC) stage, operation history, chemotherapy history, and radiotherapy history were significantly associated with aspiration (p<0.05). Among them, advanced age, increase AJCC stage, operation history, and chemotherapy history were significantly associated with aspiration in the multivariate analysis (p<0.05). Delayed swallowing reflex and reduced elevation of the larynx were significantly associated with aspiration in the multivariate analysis (p<0.05).</p>
</sec>
<sec><title>Conclusion</title>
<p>The major risk factors associated with aspiration in patients with HNC were advanced age, higher AJCC stage, operation history, and chemotherapy history. A VFSS to evaluate aspiration is needed in patients with NHC who have these risk factors. Delayed swallowing reflex and reduced elevation of the larynx were major abnormal findings associated with aspiration. Dysphagia rehabilitation should focus on these results.</p>
</sec>
</abstract>
<kwd-group><kwd>Aspiration</kwd>
<kwd>Head and neck cancer</kwd>
<kwd>Videofluoroscopic swallowing study (VFSS)</kwd>
</kwd-group>
</article-meta>
</front>
<floats-group><table-wrap id="T1" position="float"><label>Table 1</label>
<caption><p>General Subject Characteristics</p>
</caption>
<graphic xlink:href="arm-35-781-i001"></graphic>
<table-wrap-foot><fn><p>Op: Operation, CTx: Chemotherapy, RTx: Radiotherapy</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="T2" position="float"><label>Table 2</label>
<caption><p>Videofluoroscopic Swallowing Study Findings in Patients with Head and Neck Cancer</p>
</caption>
<graphic xlink:href="arm-35-781-i002"></graphic>
</table-wrap>
<table-wrap id="T3" position="float"><label>Table 3</label>
<caption><p>Incidence of Aspiration and the Univariate and Multivariate Analyses of Patient Factors</p>
</caption>
<graphic xlink:href="arm-35-781-i003"></graphic>
<table-wrap-foot><fn><p>Lx: Larynx, HPx: Hypopharynx, OPx: Oropharynx, OC:Oral cavity, NPx: Nasopharynx, SG: Salivary gland</p>
<p><sup>*</sup>
p<0.05</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="T4" position="float"><label>Table 4</label>
<caption><p>Incidence of Aspiration and the Univariate and Multivariate Analyses of Videofluroscopic Swallowing Study Findings</p>
</caption>
<graphic xlink:href="arm-35-781-i004"></graphic>
<table-wrap-foot><fn><p><sup>*</sup>
p<0.05</p>
</fn>
</table-wrap-foot>
</table-wrap>
</floats-group>
</pmc>
<affiliations><list><country><li>Corée du Sud</li>
</country>
<region><li>Région capitale de Séoul</li>
</region>
<settlement><li>Séoul</li>
</settlement>
</list>
<tree><country name="Corée du Sud"><region name="Région capitale de Séoul"><name sortKey="Jung, Soo Jin" sort="Jung, Soo Jin" uniqKey="Jung S" first="Soo Jin" last="Jung">Soo Jin Jung</name>
</region>
<name sortKey="Joo, So Young" sort="Joo, So Young" uniqKey="Joo S" first="So Young" last="Joo">So Young Joo</name>
<name sortKey="Kim, Deog Young" sort="Kim, Deog Young" uniqKey="Kim D" first="Deog Young" last="Kim">Deog Young Kim</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Pmc/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002D59 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 002D59 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Pmc |étape= Checkpoint |type= RBID |clé= PMC:3309370 |texte= Rick Factors Associated with Aspiration in Patients with Head and Neck Cancer }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:22506206" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \ | NlmPubMed2Wicri -a LymphedemaV1
![]() | This area was generated with Dilib version V0.6.31. | ![]() |