Evidence and clinical outcomes of adult soft tissue sarcomas of the extremities treated with adjuvant high-dose-rate brachytherapy – a literature review
Identifieur interne : 001B76 ( Pmc/Checkpoint ); précédent : 001B75; suivant : 001B77Evidence and clinical outcomes of adult soft tissue sarcomas of the extremities treated with adjuvant high-dose-rate brachytherapy – a literature review
Auteurs : Antonio Cássio Assis PellizzonSource :
- Journal of Contemporary Brachytherapy [ 1689-832X ] ; 2014.
Abstract
The treatment strategies for adult soft tissue sarcomas of the extremities place an emphasis on local control, maintenance of limb function, and quality of life. Surgery is the mainstay of treatment for soft tissue sarcomas. Radiotherapy and chemotherapy are also both important treatments used in these patients to optimize the outcomes of limb sparing surgery. Compared to external beam radiation therapy, brachytherapy has the advantage of delivering a concentrated dose to the tumor, whilst sparing the normal tissues. Consequently, early and late complications such as bone fractures and subcutaneous fibrosis are potentially avoided by using brachytherapy. The evidence and clinical outcomes of HDR brachytherapy in soft tissue sarcomas of the extremities are described in this paper by means of a literature review.
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DOI: 10.5114/jcb.2014.45758
PubMed: 25337137
PubMed Central: 4200188
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Evidence and clinical outcomes of adult soft tissue sarcomas of the extremities treated with adjuvant high-dose-rate brachytherapy – a literature review</title><author><name sortKey="Pellizzon, Antonio Cassio Assis" sort="Pellizzon, Antonio Cassio Assis" uniqKey="Pellizzon A" first="Antonio Cássio Assis" last="Pellizzon">Antonio Cássio Assis Pellizzon</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25337137</idno><idno type="pmc">4200188</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200188</idno><idno type="RBID">PMC:4200188</idno><idno type="doi">10.5114/jcb.2014.45758</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">004B11</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">004B11</idno><idno type="wicri:Area/Pmc/Curation">004B10</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">004B10</idno><idno type="wicri:Area/Pmc/Checkpoint">001B76</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001B76</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Evidence and clinical outcomes of adult soft tissue sarcomas of the extremities treated with adjuvant high-dose-rate brachytherapy – a literature review</title><author><name sortKey="Pellizzon, Antonio Cassio Assis" sort="Pellizzon, Antonio Cassio Assis" uniqKey="Pellizzon A" first="Antonio Cássio Assis" last="Pellizzon">Antonio Cássio Assis Pellizzon</name></author></analytic><series><title level="j">Journal of Contemporary Brachytherapy</title><idno type="ISSN">1689-832X</idno><idno type="eISSN">2081-2841</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The treatment strategies for adult soft tissue sarcomas of the extremities place an emphasis on local control, maintenance of limb function, and quality of life. Surgery is the mainstay of treatment for soft tissue sarcomas. Radiotherapy and chemotherapy are also both important treatments used in these patients to optimize the outcomes of limb sparing surgery. Compared to external beam radiation therapy, brachytherapy has the advantage of delivering a concentrated dose to the tumor, whilst sparing the normal tissues. Consequently, early and late complications such as bone fractures and subcutaneous fibrosis are potentially avoided by using brachytherapy. The evidence and clinical outcomes of HDR brachytherapy in soft tissue sarcomas of the extremities are described in this paper by means of a literature review.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Zagars, Gk" uniqKey="Zagars G">GK Zagars</name></author><author><name sortKey="Ballo, Mt" uniqKey="Ballo M">MT Ballo</name></author><author><name sortKey="Pisters, Pw" uniqKey="Pisters P">PW Pisters</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Storm, Hh" uniqKey="Storm H">HH Storm</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosenberg, Sa" uniqKey="Rosenberg S">SA Rosenberg</name></author><author><name sortKey="Tepper, J" uniqKey="Tepper J">J Tepper</name></author><author><name sortKey="Glatstein, E" uniqKey="Glatstein E">E Glatstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Viani, Ga" uniqKey="Viani G">GA 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<front><journal-meta><journal-id journal-id-type="nlm-ta">J Contemp Brachytherapy</journal-id><journal-id journal-id-type="iso-abbrev">J Contemp Brachytherapy</journal-id><journal-id journal-id-type="publisher-id">JCB</journal-id><journal-title-group><journal-title>Journal of Contemporary Brachytherapy</journal-title></journal-title-group><issn pub-type="ppub">1689-832X</issn><issn pub-type="epub">2081-2841</issn><publisher><publisher-name>Termedia Publishing House</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25337137</article-id><article-id pub-id-type="pmc">4200188</article-id><article-id pub-id-type="publisher-id">23617</article-id><article-id pub-id-type="doi">10.5114/jcb.2014.45758</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review Paper</subject></subj-group></article-categories><title-group><article-title>Evidence and clinical outcomes of adult soft tissue sarcomas of the extremities treated with adjuvant high-dose-rate brachytherapy – a literature review</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Pellizzon</surname><given-names>Antonio Cássio Assis</given-names></name><degrees>MD, PhD</degrees></contrib></contrib-group><aff>Department of Radiation Oncology, AC Camargo Cancer Center, São Paulo, Brazil</aff><author-notes><corresp id="cor1"><bold>Address for correspondence:</bold> Antonio Cássio Assis Pellizzon, MD, PhD, Department of Radiation Oncology, AC Camargo Cancer Center, Rua Professor Antonio Prudente, 211, Liberdade, São Paulo, Brazil, CEP – 01509-900. phone: + 55-1121895104. e-mail: <email xlink:href="acapellizzon@accamargo.org.br">acapellizzon@accamargo.org.br</email></corresp></author-notes><pub-date pub-type="epub"><day>06</day><month>10</month><year>2014</year></pub-date><pub-date pub-type="ppub"><month>10</month><year>2014</year></pub-date><volume>6</volume><issue>3</issue><fpage>318</fpage><lpage>322</lpage><history><date date-type="received"><day>16</day><month>7</month><year>2014</year></date><date date-type="rev-recd"><day>11</day><month>9</month><year>2014</year></date><date date-type="accepted"><day>30</day><month>9</month><year>2014</year></date></history><permissions><copyright-statement>Copyright © 2014 Termedia</copyright-statement><copyright-year>2014</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-nd/3.0/"><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p>The treatment strategies for adult soft tissue sarcomas of the extremities place an emphasis on local control, maintenance of limb function, and quality of life. Surgery is the mainstay of treatment for soft tissue sarcomas. Radiotherapy and chemotherapy are also both important treatments used in these patients to optimize the outcomes of limb sparing surgery. Compared to external beam radiation therapy, brachytherapy has the advantage of delivering a concentrated dose to the tumor, whilst sparing the normal tissues. Consequently, early and late complications such as bone fractures and subcutaneous fibrosis are potentially avoided by using brachytherapy. The evidence and clinical outcomes of HDR brachytherapy in soft tissue sarcomas of the extremities are described in this paper by means of a literature review.</p></abstract><kwd-group><kwd>brachytherapy</kwd><kwd>high-dose-rate</kwd><kwd>limb sparing surgery</kwd><kwd>radiotherapy</kwd><kwd>soft tissue sarcoma</kwd></kwd-group></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Pellizzon, Antonio Cassio Assis" sort="Pellizzon, Antonio Cassio Assis" uniqKey="Pellizzon A" first="Antonio Cássio Assis" last="Pellizzon">Antonio Cássio Assis Pellizzon</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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