LymphedemaV1, PascalFrancis, Curation, bibRecord, 000D75

Reduction of filaritic lymphoedema and elephantiasis by 5,6 benzo-a-pyrone (coumarin), and the effects of diethylcarbamazine (DEC)

Identifieur interne : 000D75 ( PascalFrancis/Curation ); précédent : 000D74; suivant : 000D76

Reduction of filaritic lymphoedema and elephantiasis by 5,6 benzo-a-pyrone (coumarin), and the effects of diethylcarbamazine (DEC)

Auteurs : J. R. Casley-Smith [Australie] ; S. Jamal ; J. R. Casley-Smith

Source :

Annals of tropical medicine and parasitology [ 0003-4983 ] ; 1993.

RBID : Pascal:93-0640187

Descripteurs français

Pascal (Inist)
- Lymphoedème, Eléphantiasis, Diéthylcarbamazine, Filariose, Système lymphatique, Antiparasitaire, Anthelminthique, Inde, Coumarine dérivé, Homme.
Wicri :
- geographic : Inde.
- topic : Homme.

English descriptors

KwdEn :
- Anthelmintic, Coumarine derivatives, Elephantiasis, Filariosis, Human, India, Lymphatic system, Lymphedema, Parasiticid.

Abstract

Chronic filaritic lymphoedema and elephantiasis, in India, were treated orally with 5,6 benzo-a-pyrone (56 BaP; 1,2 benzo-a-pyrone; coumarin) in a double-blind, randomized, matched-group trial. Each group finally contained 40-55 patients. Patients were observed for about 2 years (ranging from 6 to 45 months, with 75% completing the 2 years). The 56 BaP slowly, but very significantly (P < 0.0001), reduced all grades of lymphoedema and elephantiasis. Two thirds of the oedema was lost by grade 2 over 2 years. Grades 3 to 5 were reduced by a fifth over that time. The greater the initial oedema, the greater was its rate of resolution

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A03		`1`		`@0 Ann. trop. med. parasitol.`
A05				`@2 87`
A06				`@2 3`
A08	`01`	`1`	`ENG`	`@1 Reduction of filaritic lymphoedema and elephantiasis by 5,6 benzo-a-pyrone (coumarin), and the effects of diethylcarbamazine (DEC)`
A11	`01`	`1`		`@1 CASLEY-SMITH (J. R.)`
A11	`02`	`1`		`@1 JAMAL (S.)`
A11	`03`	`1`		`@1 CASLEY-SMITH (J. R.)`
A14	`01`			`@1 Univ. Adelaide, Henry Thomas lab. @2 Adelaide SA 5001 @3 AUS @Z 1 aut.`
A20				`@1 247-258`
A21				`@1 1993`
A23	`01`			`@0 ENG`
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A44				`@0 0000`
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A66	`01`			`@0 GBR`
C01	`01`		`ENG`	@0 Chronic filaritic lymphoedema and elephantiasis, in India, were treated orally with 5,6 benzo-a-pyrone (56 BaP; 1,2 benzo-a-pyrone; coumarin) in a double-blind, randomized, matched-group trial. Each group finally contained 40-55 patients. Patients were observed for about 2 years (ranging from 6 to 45 months, with 75% completing the 2 years). The 56 BaP slowly, but very significantly (P < 0.0001), reduced all grades of lymphoedema and elephantiasis. Two thirds of the oedema was lost by grade 2 over 2 years. Grades 3 to 5 were reduced by a fifth over that time. The greater the initial oedema, the greater was its rate of resolution
C02	`01`	`X`		`@0 002B02S06`
C02	`02`	`X`		`@0 235`
C03	`01`	`X`	`FRE`	`@0 Lymphoedème @5 01`
C03	`01`	`X`	`ENG`	`@0 Lymphedema @5 01`
C03	`01`	`X`	`SPA`	`@0 Linfedema @5 01`
C03	`02`	`X`	`FRE`	`@0 Eléphantiasis @5 02`
C03	`02`	`X`	`ENG`	`@0 Elephantiasis @5 02`
C03	`02`	`X`	`SPA`	`@0 Elefantiasis @5 02`
C03	`03`	`X`	`FRE`	`@0 Diéthylcarbamazine @2 NK @2 FR @5 03`
C03	`04`	`X`	`FRE`	`@0 Filariose @2 NM @2 L1 @5 06`
C03	`04`	`X`	`ENG`	`@0 Filariosis @2 NM @2 L1 @5 06`
C03	`04`	`X`	`SPA`	`@0 Filariosis @2 NM @2 L1 @5 06`
C03	`05`	`X`	`FRE`	`@0 Système lymphatique @2 L1 @5 07`
C03	`05`	`X`	`ENG`	`@0 Lymphatic system @2 L1 @5 07`
C03	`05`	`X`	`SPA`	`@0 Sistema linfático @2 L1 @5 07`
C03	`06`	`X`	`FRE`	`@0 Antiparasitaire @5 18`
C03	`06`	`X`	`ENG`	`@0 Parasiticid @5 18`
C03	`06`	`X`	`SPA`	`@0 Antiparasitario @5 18`
C03	`07`	`X`	`FRE`	`@0 Anthelminthique @5 19`
C03	`07`	`X`	`ENG`	`@0 Anthelmintic @5 19`
C03	`07`	`X`	`SPA`	`@0 Antihelmíntico @5 19`
C03	`08`	`X`	`FRE`	`@0 Inde @2 NG @5 44`
C03	`08`	`X`	`ENG`	`@0 India @2 NG @5 44`
C03	`08`	`X`	`GER`	`@0 Indien @2 NG @5 44`
C03	`08`	`X`	`SPA`	`@0 India @2 NG @5 44`
C03	`09`	`X`	`FRE`	`@0 Coumarine dérivé @2 NK @2 FR @5 94`
C03	`09`	`X`	`ENG`	`@0 Coumarine derivatives @2 NK @2 FR @5 94`
C03	`10`	`X`	`FRE`	`@0 Homme @5 95`
C03	`10`	`X`	`ENG`	`@0 Human @5 95`
C03	`10`	`X`	`SPA`	`@0 Hombre @5 95`
C07	`01`	`X`	`FRE`	`@0 Nématodose`
C07	`01`	`X`	`ENG`	`@0 Nematod disease`
C07	`01`	`X`	`SPA`	`@0 Nematodosis`
C07	`02`	`X`	`FRE`	`@0 Helminthiase`
C07	`02`	`X`	`ENG`	`@0 Helminthiasis`
C07	`02`	`X`	`SPA`	`@0 Helmintiasis`
C07	`03`	`X`	`FRE`	`@0 Infection`
C07	`03`	`X`	`ENG`	`@0 Infection`
C07	`03`	`X`	`SPA`	`@0 Infección`
C07	`04`	`X`	`FRE`	`@0 Asie @2 NG`
C07	`04`	`X`	`ENG`	`@0 Asia @2 NG`
C07	`04`	`X`	`GER`	`@0 Asien @2 NG`
C07	`04`	`X`	`SPA`	`@0 Asia @2 NG`
N21				`@1 328`

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Pascal:93-0640187

Le document en format XML

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<author><name sortKey="Casley Smith, J R" sort="Casley Smith, J R" uniqKey="Casley Smith J" first="J. R." last="Casley-Smith">J. R. Casley-Smith</name>
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<author><name sortKey="Jamal, S" sort="Jamal, S" uniqKey="Jamal S" first="S." last="Jamal">S. Jamal</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anthelmintic</term>
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<front><div type="abstract" xml:lang="en">Chronic filaritic lymphoedema and elephantiasis, in India, were treated orally with 5,6 benzo-a-pyrone (56 BaP; 1,2 benzo-a-pyrone; coumarin) in a double-blind, randomized, matched-group trial. Each group finally contained 40-55 patients. Patients were observed for about 2 years (ranging from 6 to 45 months, with 75% completing the 2 years). The 56 BaP slowly, but very significantly (P < 0.0001), reduced all grades of lymphoedema and elephantiasis. Two thirds of the oedema was lost by grade 2 over 2 years. Grades 3 to 5 were reduced by a fifth over that time. The greater the initial oedema, the greater was its rate of resolution</div>
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Reduction of filaritic lymphoedema and elephantiasis by 5,6 benzo-a-pyrone (coumarin), and the effects of diethylcarbamazine (DEC)

Reduction of filaritic lymphoedema and elephantiasis by 5,6 benzo-a-pyrone (coumarin), and the effects of diethylcarbamazine (DEC)

Source :

Descripteurs français

English descriptors

Abstract

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Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri