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Forearm blood flow measured by venous occlusion plethysmography in healthy subjects and in women with postmastectomy oedema

Identifieur interne : 000A94 ( PascalFrancis/Corpus ); précédent : 000A93; suivant : 000A95

Forearm blood flow measured by venous occlusion plethysmography in healthy subjects and in women with postmastectomy oedema

Auteurs : A. W. B. Stanton ; B. Holroyd ; J. W. Northfield ; J. R. Levick ; P. S. Mortimer

Source :

RBID : Pascal:98-0308089

Descripteurs français

English descriptors

Abstract

A chronic swelling of the arm may develop following damage to axillary lymph vessels during breast cancer treatment. Certain unusual pathophysiological features of postmastectomy oedema indicate that factors additional to lymphatic damage are important. One factor postulated previously is a haemodynamic abnormality. Forearm blood flow was therefore measured by venous occlusion plethysmography using both a conventional mercury strain gauge and a newer optical volumeter (Perometer®). The latter was initially assessed in healthy subjects. When forearm blood flow was measured using the two methods simultaneously, the strain gauge and Perometer® did not differ significantly for healthy or oedematous arms. Dominant and non-dominant arm blood flow in healthy subjects was similar but with greater variation between sides with the Perometer®. Using the strain gauge, blood flow in the oedematous arm (2.51±1.33 ml/100 ml per min) was significantly lower than in the opposite unaffected arm (3.77±2.29 ml/100 ml per min; p = 0.026). The Perometer® results showed a similar but non-significant trend (p = 0.105). Taking into account the greater limb volume on the affected side, total forearm blood flow was essentially the same in each arm (unaffected: 40.72 ± 28.70 ml/min; oedematous: 41.78 ± 22.11 ml/min). The reduced blood flow per unit volume of arm was therefore likely to be due to a simple 'dilution' effect of the increase in volume. The results indicate that it is unlikely that raised blood flow contributes to oedema formation, contrary to the haemodynamic concept.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 1358-863X
A03   1    @0 Vasc. med. : (Lond.)
A05       @2 3
A06       @2 1
A08 01  1  ENG  @1 Forearm blood flow measured by venous occlusion plethysmography in healthy subjects and in women with postmastectomy oedema
A11 01  1    @1 STANTON (A. W. B.)
A11 02  1    @1 HOLROYD (B.)
A11 03  1    @1 NORTHFIELD (J. W.)
A11 04  1    @1 LEVICK (J. R.)
A11 05  1    @1 MORTIMER (P. S.)
A14 01      @1 Department of Medicine, Division of Physiological Medicine (Dermatology), St George's Hospital Medical School @2 London @3 GBR @Z 1 aut. @Z 5 aut.
A14 02      @1 St George's Hospital Medical School @2 London @3 GBR @Z 2 aut.
A14 03      @1 Mayday Hospital @2 Croydon @3 GBR @Z 3 aut.
A14 04      @1 Department of Physiology, St George's Hospital Medical School @2 London @3 GBR @Z 4 aut.
A20       @1 3-8
A21       @1 1998
A23 01      @0 ENG
A43 01      @1 INIST @2 26454 @5 354000076425570010
A44       @0 0000 @1 © 1998 INIST-CNRS. All rights reserved.
A45       @0 19 ref.
A47 01  1    @0 98-0308089
A60       @1 P
A61       @0 A
A64   1    @0 Vascular medicine : (London)
A66 01      @0 GBR
C01 01    ENG  @0 A chronic swelling of the arm may develop following damage to axillary lymph vessels during breast cancer treatment. Certain unusual pathophysiological features of postmastectomy oedema indicate that factors additional to lymphatic damage are important. One factor postulated previously is a haemodynamic abnormality. Forearm blood flow was therefore measured by venous occlusion plethysmography using both a conventional mercury strain gauge and a newer optical volumeter (Perometer®). The latter was initially assessed in healthy subjects. When forearm blood flow was measured using the two methods simultaneously, the strain gauge and Perometer® did not differ significantly for healthy or oedematous arms. Dominant and non-dominant arm blood flow in healthy subjects was similar but with greater variation between sides with the Perometer®. Using the strain gauge, blood flow in the oedematous arm (2.51±1.33 ml/100 ml per min) was significantly lower than in the opposite unaffected arm (3.77±2.29 ml/100 ml per min; p = 0.026). The Perometer® results showed a similar but non-significant trend (p = 0.105). Taking into account the greater limb volume on the affected side, total forearm blood flow was essentially the same in each arm (unaffected: 40.72 ± 28.70 ml/min; oedematous: 41.78 ± 22.11 ml/min). The reduced blood flow per unit volume of arm was therefore likely to be due to a simple 'dilution' effect of the increase in volume. The results indicate that it is unlikely that raised blood flow contributes to oedema formation, contrary to the haemodynamic concept.
C02 01  X    @0 002B25K
C03 01  X  FRE  @0 Lymphoedème @5 01
C03 01  X  ENG  @0 Lymphedema @5 01
C03 01  X  SPA  @0 Linfedema @5 01
C03 02  X  FRE  @0 Membre supérieur @5 02
C03 02  X  ENG  @0 Upper limb @5 02
C03 02  X  SPA  @0 Miembro superior @5 02
C03 03  X  FRE  @0 Pléthysmographie @5 04
C03 03  X  ENG  @0 Plethysmography @5 04
C03 03  X  SPA  @0 Pletismografía @5 04
C03 04  X  FRE  @0 Débit sanguin @5 07
C03 04  X  ENG  @0 Blood flow @5 07
C03 04  X  SPA  @0 Flujo sanguíneo @5 07
C03 05  X  FRE  @0 Avant bras @5 08
C03 05  X  ENG  @0 Forearm @5 08
C03 05  X  SPA  @0 Antebrazo @5 08
C03 06  X  FRE  @0 Résection chirurgicale @5 10
C03 06  X  ENG  @0 Surgical resection @5 10
C03 06  X  SPA  @0 Resección quirúrgica @5 10
C03 07  X  FRE  @0 Glande mammaire @5 11
C03 07  X  ENG  @0 Mammary gland @5 11
C03 07  X  SPA  @0 Glándula mamaria @5 11
C03 08  X  FRE  @0 Technique @5 16
C03 08  X  ENG  @0 Technique @5 16
C03 08  X  SPA  @0 Técnica @5 16
C03 09  X  FRE  @0 Traitement @5 17
C03 09  X  ENG  @0 Treatment @5 17
C03 09  X  GER  @0 Aufbereiten @5 17
C03 09  X  SPA  @0 Tratamiento @5 17
C03 10  X  FRE  @0 Complication @5 18
C03 10  X  ENG  @0 Complication @5 18
C03 10  X  SPA  @0 Complicación @5 18
C03 11  X  FRE  @0 Exploration @5 19
C03 11  X  ENG  @0 Exploration @5 19
C03 11  X  SPA  @0 Exploración @5 19
C03 12  X  FRE  @0 Homme @5 20
C03 12  X  ENG  @0 Human @5 20
C03 12  X  SPA  @0 Hombre @5 20
C03 13  X  FRE  @0 Sexe @5 21
C03 13  X  ENG  @0 Sex @5 21
C03 13  X  SPA  @0 Sexo @5 21
C03 14  X  FRE  @0 Femelle @5 22
C03 14  X  ENG  @0 Female @5 22
C03 14  X  SPA  @0 Hembra @5 22
C07 01  X  FRE  @0 Appareil circulatoire pathologie @5 37
C07 01  X  ENG  @0 Cardiovascular disease @5 37
C07 01  X  SPA  @0 Aparato circulatorio patología @5 37
C07 02  X  FRE  @0 Lymphatique pathologie @5 38
C07 02  X  ENG  @0 Lymphatic vessel disease @5 38
C07 02  X  SPA  @0 Linfático patología @5 38
C07 03  X  FRE  @0 Chirurgie @5 61
C07 03  X  ENG  @0 Surgery @5 61
C07 03  X  SPA  @0 Cirugía @5 61
N21       @1 208

Format Inist (serveur)

NO : PASCAL 98-0308089 INIST
ET : Forearm blood flow measured by venous occlusion plethysmography in healthy subjects and in women with postmastectomy oedema
AU : STANTON (A. W. B.); HOLROYD (B.); NORTHFIELD (J. W.); LEVICK (J. R.); MORTIMER (P. S.)
AF : Department of Medicine, Division of Physiological Medicine (Dermatology), St George's Hospital Medical School/London/Royaume-Uni (1 aut., 5 aut.); St George's Hospital Medical School/London/Royaume-Uni (2 aut.); Mayday Hospital/Croydon/Royaume-Uni (3 aut.); Department of Physiology, St George's Hospital Medical School/London/Royaume-Uni (4 aut.)
DT : Publication en série; Niveau analytique
SO : Vascular medicine : (London); ISSN 1358-863X; Royaume-Uni; Da. 1998; Vol. 3; No. 1; Pp. 3-8; Bibl. 19 ref.
LA : Anglais
EA : A chronic swelling of the arm may develop following damage to axillary lymph vessels during breast cancer treatment. Certain unusual pathophysiological features of postmastectomy oedema indicate that factors additional to lymphatic damage are important. One factor postulated previously is a haemodynamic abnormality. Forearm blood flow was therefore measured by venous occlusion plethysmography using both a conventional mercury strain gauge and a newer optical volumeter (Perometer®). The latter was initially assessed in healthy subjects. When forearm blood flow was measured using the two methods simultaneously, the strain gauge and Perometer® did not differ significantly for healthy or oedematous arms. Dominant and non-dominant arm blood flow in healthy subjects was similar but with greater variation between sides with the Perometer®. Using the strain gauge, blood flow in the oedematous arm (2.51±1.33 ml/100 ml per min) was significantly lower than in the opposite unaffected arm (3.77±2.29 ml/100 ml per min; p = 0.026). The Perometer® results showed a similar but non-significant trend (p = 0.105). Taking into account the greater limb volume on the affected side, total forearm blood flow was essentially the same in each arm (unaffected: 40.72 ± 28.70 ml/min; oedematous: 41.78 ± 22.11 ml/min). The reduced blood flow per unit volume of arm was therefore likely to be due to a simple 'dilution' effect of the increase in volume. The results indicate that it is unlikely that raised blood flow contributes to oedema formation, contrary to the haemodynamic concept.
CC : 002B25K
FD : Lymphoedème; Membre supérieur; Pléthysmographie; Débit sanguin; Avant bras; Résection chirurgicale; Glande mammaire; Technique; Traitement; Complication; Exploration; Homme; Sexe; Femelle
FG : Appareil circulatoire pathologie; Lymphatique pathologie; Chirurgie
ED : Lymphedema; Upper limb; Plethysmography; Blood flow; Forearm; Surgical resection; Mammary gland; Technique; Treatment; Complication; Exploration; Human; Sex; Female
EG : Cardiovascular disease; Lymphatic vessel disease; Surgery
GD : Aufbereiten
SD : Linfedema; Miembro superior; Pletismografía; Flujo sanguíneo; Antebrazo; Resección quirúrgica; Glándula mamaria; Técnica; Tratamiento; Complicación; Exploración; Hombre; Sexo; Hembra
LO : INIST-26454.354000076425570010
ID : 98-0308089

Links to Exploration step

Pascal:98-0308089

Le document en format XML

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<div type="abstract" xml:lang="en">A chronic swelling of the arm may develop following damage to axillary lymph vessels during breast cancer treatment. Certain unusual pathophysiological features of postmastectomy oedema indicate that factors additional to lymphatic damage are important. One factor postulated previously is a haemodynamic abnormality. Forearm blood flow was therefore measured by venous occlusion plethysmography using both a conventional mercury strain gauge and a newer optical volumeter (Perometer®). The latter was initially assessed in healthy subjects. When forearm blood flow was measured using the two methods simultaneously, the strain gauge and Perometer® did not differ significantly for healthy or oedematous arms. Dominant and non-dominant arm blood flow in healthy subjects was similar but with greater variation between sides with the Perometer®. Using the strain gauge, blood flow in the oedematous arm (2.51±1.33 ml/100 ml per min) was significantly lower than in the opposite unaffected arm (3.77±2.29 ml/100 ml per min; p = 0.026). The Perometer® results showed a similar but non-significant trend (p = 0.105). Taking into account the greater limb volume on the affected side, total forearm blood flow was essentially the same in each arm (unaffected: 40.72 ± 28.70 ml/min; oedematous: 41.78 ± 22.11 ml/min). The reduced blood flow per unit volume of arm was therefore likely to be due to a simple 'dilution' effect of the increase in volume. The results indicate that it is unlikely that raised blood flow contributes to oedema formation, contrary to the haemodynamic concept.</div>
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<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Miembro superior</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Pléthysmographie</s0>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Plethysmography</s0>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Pletismografía</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Débit sanguin</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Blood flow</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Flujo sanguíneo</s0>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Avant bras</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Forearm</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Antebrazo</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Résection chirurgicale</s0>
<s5>10</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Surgical resection</s0>
<s5>10</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Resección quirúrgica</s0>
<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Glande mammaire</s0>
<s5>11</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Mammary gland</s0>
<s5>11</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Glándula mamaria</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE">
<s0>Technique</s0>
<s5>16</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG">
<s0>Technique</s0>
<s5>16</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA">
<s0>Técnica</s0>
<s5>16</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE">
<s0>Traitement</s0>
<s5>17</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG">
<s0>Treatment</s0>
<s5>17</s5>
</fC03>
<fC03 i1="09" i2="X" l="GER">
<s0>Aufbereiten</s0>
<s5>17</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA">
<s0>Tratamiento</s0>
<s5>17</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE">
<s0>Complication</s0>
<s5>18</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG">
<s0>Complication</s0>
<s5>18</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA">
<s0>Complicación</s0>
<s5>18</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE">
<s0>Exploration</s0>
<s5>19</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG">
<s0>Exploration</s0>
<s5>19</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA">
<s0>Exploración</s0>
<s5>19</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE">
<s0>Homme</s0>
<s5>20</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG">
<s0>Human</s0>
<s5>20</s5>
</fC03>
<fC03 i1="12" i2="X" l="SPA">
<s0>Hombre</s0>
<s5>20</s5>
</fC03>
<fC03 i1="13" i2="X" l="FRE">
<s0>Sexe</s0>
<s5>21</s5>
</fC03>
<fC03 i1="13" i2="X" l="ENG">
<s0>Sex</s0>
<s5>21</s5>
</fC03>
<fC03 i1="13" i2="X" l="SPA">
<s0>Sexo</s0>
<s5>21</s5>
</fC03>
<fC03 i1="14" i2="X" l="FRE">
<s0>Femelle</s0>
<s5>22</s5>
</fC03>
<fC03 i1="14" i2="X" l="ENG">
<s0>Female</s0>
<s5>22</s5>
</fC03>
<fC03 i1="14" i2="X" l="SPA">
<s0>Hembra</s0>
<s5>22</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Appareil circulatoire pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Cardiovascular disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Aparato circulatorio patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Lymphatique pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Lymphatic vessel disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Linfático patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Chirurgie</s0>
<s5>61</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Surgery</s0>
<s5>61</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Cirugía</s0>
<s5>61</s5>
</fC07>
<fN21>
<s1>208</s1>
</fN21>
</pA>
</standard>
<server>
<NO>PASCAL 98-0308089 INIST</NO>
<ET>Forearm blood flow measured by venous occlusion plethysmography in healthy subjects and in women with postmastectomy oedema</ET>
<AU>STANTON (A. W. B.); HOLROYD (B.); NORTHFIELD (J. W.); LEVICK (J. R.); MORTIMER (P. S.)</AU>
<AF>Department of Medicine, Division of Physiological Medicine (Dermatology), St George's Hospital Medical School/London/Royaume-Uni (1 aut., 5 aut.); St George's Hospital Medical School/London/Royaume-Uni (2 aut.); Mayday Hospital/Croydon/Royaume-Uni (3 aut.); Department of Physiology, St George's Hospital Medical School/London/Royaume-Uni (4 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Vascular medicine : (London); ISSN 1358-863X; Royaume-Uni; Da. 1998; Vol. 3; No. 1; Pp. 3-8; Bibl. 19 ref.</SO>
<LA>Anglais</LA>
<EA>A chronic swelling of the arm may develop following damage to axillary lymph vessels during breast cancer treatment. Certain unusual pathophysiological features of postmastectomy oedema indicate that factors additional to lymphatic damage are important. One factor postulated previously is a haemodynamic abnormality. Forearm blood flow was therefore measured by venous occlusion plethysmography using both a conventional mercury strain gauge and a newer optical volumeter (Perometer®). The latter was initially assessed in healthy subjects. When forearm blood flow was measured using the two methods simultaneously, the strain gauge and Perometer® did not differ significantly for healthy or oedematous arms. Dominant and non-dominant arm blood flow in healthy subjects was similar but with greater variation between sides with the Perometer®. Using the strain gauge, blood flow in the oedematous arm (2.51±1.33 ml/100 ml per min) was significantly lower than in the opposite unaffected arm (3.77±2.29 ml/100 ml per min; p = 0.026). The Perometer® results showed a similar but non-significant trend (p = 0.105). Taking into account the greater limb volume on the affected side, total forearm blood flow was essentially the same in each arm (unaffected: 40.72 ± 28.70 ml/min; oedematous: 41.78 ± 22.11 ml/min). The reduced blood flow per unit volume of arm was therefore likely to be due to a simple 'dilution' effect of the increase in volume. The results indicate that it is unlikely that raised blood flow contributes to oedema formation, contrary to the haemodynamic concept.</EA>
<CC>002B25K</CC>
<FD>Lymphoedème; Membre supérieur; Pléthysmographie; Débit sanguin; Avant bras; Résection chirurgicale; Glande mammaire; Technique; Traitement; Complication; Exploration; Homme; Sexe; Femelle</FD>
<FG>Appareil circulatoire pathologie; Lymphatique pathologie; Chirurgie</FG>
<ED>Lymphedema; Upper limb; Plethysmography; Blood flow; Forearm; Surgical resection; Mammary gland; Technique; Treatment; Complication; Exploration; Human; Sex; Female</ED>
<EG>Cardiovascular disease; Lymphatic vessel disease; Surgery</EG>
<GD>Aufbereiten</GD>
<SD>Linfedema; Miembro superior; Pletismografía; Flujo sanguíneo; Antebrazo; Resección quirúrgica; Glándula mamaria; Técnica; Tratamiento; Complicación; Exploración; Hombre; Sexo; Hembra</SD>
<LO>INIST-26454.354000076425570010</LO>
<ID>98-0308089</ID>
</server>
</inist>
</record>

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