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Sodium selenite as prophylaxis against erysipelas in secondary lymphedema

Identifieur interne : 000A73 ( PascalFrancis/Corpus ); précédent : 000A72; suivant : 000A74

Sodium selenite as prophylaxis against erysipelas in secondary lymphedema

Auteurs : R. Kasseroller

Source :

RBID : Pascal:98-0480585

Descripteurs français

English descriptors

Abstract

In a randomised, double-blind study, the efficacy of sodium selenite application in combination with physical therapy to relieve congestion was investigated in a cohort of 60 cancer patients with secondary lymph edema, with special reference to the development of the incidence of erysipelas. All of the patients investigated in this study had erysipelas infection of the skin. Selenium was administered in pharmacological doses. The duration of physical therapy was three weeks. Patients were under observation for a further three months. The incidence of erysipelas among our patients was 11%. During the three-week period of intensive treatment, there was not a single case of erysipelas in the treatment group, whereas there was one single case in the placebo group. In the follow-up period (3 months), once again there was not a single case of erysipelas in the treatment group, but 50% of the patients in the placebo group exhibited erysipelas. In spite of higher doses, the selenium level did not rise above normal values. Patients under long-term antibiotic therapy suffered no relapse when the antibiotic therapy was stopped and instead, selenium was administered. It could be shown, in addition, that by administration of a single high-dose of sodium selenite, inflammation could be immediately brought under control.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0250-7005
A03   1    @0 Anticancer res.
A05       @2 18
A06       @2 3C
A08 01  1  ENG  @1 Sodium selenite as prophylaxis against erysipelas in secondary lymphedema
A09 01  1  ENG  @1 Diagnosis and treatment of breast cancer
A11 01  1    @1 KASSEROLLER (R.)
A12 01  1    @1 SCHAUER (A.) @9 ed.
A12 02  1    @1 MEDEN (H.) @9 ed.
A14 01      @1 Wittlinger's Therapy Center, Alleestrasse 30 @2 6344 Walchsee @3 AUT @Z 1 aut.
A15 01      @1 Department of Pathology, University of Göttingen, Robert-Koch-Str. 40 @2 37075 Göttingen @3 DEU @Z 1 aut.
A15 02      @1 Department of Gynecology and Obstetrics, University of Göttingen, Robert-Koch-Str. 40 @2 37075 Göttingen @3 DEU @Z 2 aut.
A20       @1 2227-2230
A21       @1 1998
A23 01      @0 ENG
A43 01      @1 INIST @2 19426 @5 354000072626610210
A44       @0 0000 @1 © 1998 INIST-CNRS. All rights reserved.
A45       @0 12 ref.
A47 01  1    @0 98-0480585
A60       @1 P
A61       @0 A
A64   1    @0 Anticancer research
A66 01      @0 GRC
C01 01    ENG  @0 In a randomised, double-blind study, the efficacy of sodium selenite application in combination with physical therapy to relieve congestion was investigated in a cohort of 60 cancer patients with secondary lymph edema, with special reference to the development of the incidence of erysipelas. All of the patients investigated in this study had erysipelas infection of the skin. Selenium was administered in pharmacological doses. The duration of physical therapy was three weeks. Patients were under observation for a further three months. The incidence of erysipelas among our patients was 11%. During the three-week period of intensive treatment, there was not a single case of erysipelas in the treatment group, whereas there was one single case in the placebo group. In the follow-up period (3 months), once again there was not a single case of erysipelas in the treatment group, but 50% of the patients in the placebo group exhibited erysipelas. In spite of higher doses, the selenium level did not rise above normal values. Patients under long-term antibiotic therapy suffered no relapse when the antibiotic therapy was stopped and instead, selenium was administered. It could be shown, in addition, that by administration of a single high-dose of sodium selenite, inflammation could be immediately brought under control.
C02 01  X    @0 002B02S02
C03 01  X  FRE  @0 Lymphoedème @5 01
C03 01  X  ENG  @0 Lymphedema @5 01
C03 01  X  SPA  @0 Linfedema @5 01
C03 02  X  FRE  @0 Complication @5 02
C03 02  X  ENG  @0 Complication @5 02
C03 02  X  SPA  @0 Complicación @5 02
C03 03  X  FRE  @0 Chirurgie @5 03
C03 03  X  ENG  @0 Surgery @5 03
C03 03  X  SPA  @0 Cirugía @5 03
C03 04  X  FRE  @0 Tumeur maligne @5 04
C03 04  X  ENG  @0 Malignant tumor @5 04
C03 04  X  SPA  @0 Tumor maligno @5 04
C03 05  X  FRE  @0 Glande mammaire @5 05
C03 05  X  ENG  @0 Mammary gland @5 05
C03 05  X  SPA  @0 Glándula mamaria @5 05
C03 06  X  FRE  @0 Homme @5 06
C03 06  X  ENG  @0 Human @5 06
C03 06  X  SPA  @0 Hombre @5 06
C03 07  X  FRE  @0 Sodium Sélénite @2 NC @2 NA @5 07
C03 07  X  ENG  @0 Sodium Selenites @2 NC @2 NA @5 07
C03 07  X  SPA  @0 Sodio Selenito @2 NC @2 NA @5 07
C03 08  X  FRE  @0 Voie externe @5 08
C03 08  X  ENG  @0 Topical administration @5 08
C03 08  X  SPA  @0 Vía externa @5 08
C03 09  X  FRE  @0 Voie locale @5 09
C03 09  X  ENG  @0 Local administration @5 09
C03 09  X  SPA  @0 Vía local @5 09
C03 10  X  FRE  @0 Etude cohorte @5 10
C03 10  X  ENG  @0 Cohort study @5 10
C03 10  X  SPA  @0 Estudio cohorte @5 10
C03 11  X  FRE  @0 Sélénium @2 NC @5 11
C03 11  X  ENG  @0 Selenium @2 NC @5 11
C03 11  X  GER  @0 Selen @2 NC @5 11
C03 11  X  SPA  @0 Selenio @2 NC @5 11
C03 12  X  FRE  @0 Erysipèle @5 13
C03 12  X  ENG  @0 Erysipelas @5 13
C03 12  X  SPA  @0 Erisipela @5 13
C03 13  X  FRE  @0 Prévention @5 17
C03 13  X  ENG  @0 Prevention @5 17
C03 13  X  SPA  @0 Prevención @5 17
C03 14  X  FRE  @0 Randomisation @5 18
C03 14  X  ENG  @0 Randomization @5 18
C03 14  X  SPA  @0 Aleatorización @5 18
C03 15  X  FRE  @0 Etude double insu @5 19
C03 15  X  ENG  @0 Double blind study @5 19
C03 15  X  SPA  @0 Estudio doble ciego @5 19
C03 16  X  FRE  @0 Essai clinique @5 20
C03 16  X  ENG  @0 Clinical trial @5 20
C03 16  X  SPA  @0 Ensayo clínico @5 20
C03 17  X  FRE  @0 Antiinflammatoire @5 21
C03 17  X  ENG  @0 Antiinflammatory agent @5 21
C03 17  X  SPA  @0 Antiinflamatorio @5 21
C07 01  X  FRE  @0 Streptococcie
C07 01  X  ENG  @0 Streptococcal infection
C07 01  X  SPA  @0 Estreptococia
C07 02  X  FRE  @0 Bactériose
C07 02  X  ENG  @0 Bacteriosis
C07 02  X  SPA  @0 Bacteriosis
C07 03  X  FRE  @0 Infection
C07 03  X  ENG  @0 Infection
C07 03  X  SPA  @0 Infección
C07 04  X  FRE  @0 Appareil circulatoire pathologie @5 37
C07 04  X  ENG  @0 Cardiovascular disease @5 37
C07 04  X  SPA  @0 Aparato circulatorio patología @5 37
C07 05  X  FRE  @0 Lymphatique pathologie @5 38
C07 05  X  ENG  @0 Lymphatic vessel disease @5 38
C07 05  X  SPA  @0 Linfático patología @5 38
C07 06  X  FRE  @0 Glande mammaire pathologie @5 45
C07 06  X  ENG  @0 Mammary gland diseases @5 45
C07 06  X  SPA  @0 Glándula mamaria patología @5 45
N21       @1 313

Format Inist (serveur)

NO : PASCAL 98-0480585 INIST
ET : Sodium selenite as prophylaxis against erysipelas in secondary lymphedema
AU : KASSEROLLER (R.); SCHAUER (A.); MEDEN (H.)
AF : Wittlinger's Therapy Center, Alleestrasse 30/6344 Walchsee/Autriche (1 aut.); Department of Pathology, University of Göttingen, Robert-Koch-Str. 40/37075 Göttingen/Allemagne (1 aut.); Department of Gynecology and Obstetrics, University of Göttingen, Robert-Koch-Str. 40/37075 Göttingen/Allemagne (2 aut.)
DT : Publication en série; Niveau analytique
SO : Anticancer research; ISSN 0250-7005; Grèce; Da. 1998; Vol. 18; No. 3C; Pp. 2227-2230; Bibl. 12 ref.
LA : Anglais
EA : In a randomised, double-blind study, the efficacy of sodium selenite application in combination with physical therapy to relieve congestion was investigated in a cohort of 60 cancer patients with secondary lymph edema, with special reference to the development of the incidence of erysipelas. All of the patients investigated in this study had erysipelas infection of the skin. Selenium was administered in pharmacological doses. The duration of physical therapy was three weeks. Patients were under observation for a further three months. The incidence of erysipelas among our patients was 11%. During the three-week period of intensive treatment, there was not a single case of erysipelas in the treatment group, whereas there was one single case in the placebo group. In the follow-up period (3 months), once again there was not a single case of erysipelas in the treatment group, but 50% of the patients in the placebo group exhibited erysipelas. In spite of higher doses, the selenium level did not rise above normal values. Patients under long-term antibiotic therapy suffered no relapse when the antibiotic therapy was stopped and instead, selenium was administered. It could be shown, in addition, that by administration of a single high-dose of sodium selenite, inflammation could be immediately brought under control.
CC : 002B02S02
FD : Lymphoedème; Complication; Chirurgie; Tumeur maligne; Glande mammaire; Homme; Sodium Sélénite; Voie externe; Voie locale; Etude cohorte; Sélénium; Erysipèle; Prévention; Randomisation; Etude double insu; Essai clinique; Antiinflammatoire
FG : Streptococcie; Bactériose; Infection; Appareil circulatoire pathologie; Lymphatique pathologie; Glande mammaire pathologie
ED : Lymphedema; Complication; Surgery; Malignant tumor; Mammary gland; Human; Sodium Selenites; Topical administration; Local administration; Cohort study; Selenium; Erysipelas; Prevention; Randomization; Double blind study; Clinical trial; Antiinflammatory agent
EG : Streptococcal infection; Bacteriosis; Infection; Cardiovascular disease; Lymphatic vessel disease; Mammary gland diseases
GD : Selen
SD : Linfedema; Complicación; Cirugía; Tumor maligno; Glándula mamaria; Hombre; Sodio Selenito; Vía externa; Vía local; Estudio cohorte; Selenio; Erisipela; Prevención; Aleatorización; Estudio doble ciego; Ensayo clínico; Antiinflamatorio
LO : INIST-19426.354000072626610210
ID : 98-0480585

Links to Exploration step

Pascal:98-0480585

Le document en format XML

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<div type="abstract" xml:lang="en">In a randomised, double-blind study, the efficacy of sodium selenite application in combination with physical therapy to relieve congestion was investigated in a cohort of 60 cancer patients with secondary lymph edema, with special reference to the development of the incidence of erysipelas. All of the patients investigated in this study had erysipelas infection of the skin. Selenium was administered in pharmacological doses. The duration of physical therapy was three weeks. Patients were under observation for a further three months. The incidence of erysipelas among our patients was 11%. During the three-week period of intensive treatment, there was not a single case of erysipelas in the treatment group, whereas there was one single case in the placebo group. In the follow-up period (3 months), once again there was not a single case of erysipelas in the treatment group, but 50% of the patients in the placebo group exhibited erysipelas. In spite of higher doses, the selenium level did not rise above normal values. Patients under long-term antibiotic therapy suffered no relapse when the antibiotic therapy was stopped and instead, selenium was administered. It could be shown, in addition, that by administration of a single high-dose of sodium selenite, inflammation could be immediately brought under control.</div>
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<fC03 i1="10" i2="X" l="ENG">
<s0>Cohort study</s0>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA">
<s0>Estudio cohorte</s0>
<s5>10</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE">
<s0>Sélénium</s0>
<s2>NC</s2>
<s5>11</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG">
<s0>Selenium</s0>
<s2>NC</s2>
<s5>11</s5>
</fC03>
<fC03 i1="11" i2="X" l="GER">
<s0>Selen</s0>
<s2>NC</s2>
<s5>11</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA">
<s0>Selenio</s0>
<s2>NC</s2>
<s5>11</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE">
<s0>Erysipèle</s0>
<s5>13</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG">
<s0>Erysipelas</s0>
<s5>13</s5>
</fC03>
<fC03 i1="12" i2="X" l="SPA">
<s0>Erisipela</s0>
<s5>13</s5>
</fC03>
<fC03 i1="13" i2="X" l="FRE">
<s0>Prévention</s0>
<s5>17</s5>
</fC03>
<fC03 i1="13" i2="X" l="ENG">
<s0>Prevention</s0>
<s5>17</s5>
</fC03>
<fC03 i1="13" i2="X" l="SPA">
<s0>Prevención</s0>
<s5>17</s5>
</fC03>
<fC03 i1="14" i2="X" l="FRE">
<s0>Randomisation</s0>
<s5>18</s5>
</fC03>
<fC03 i1="14" i2="X" l="ENG">
<s0>Randomization</s0>
<s5>18</s5>
</fC03>
<fC03 i1="14" i2="X" l="SPA">
<s0>Aleatorización</s0>
<s5>18</s5>
</fC03>
<fC03 i1="15" i2="X" l="FRE">
<s0>Etude double insu</s0>
<s5>19</s5>
</fC03>
<fC03 i1="15" i2="X" l="ENG">
<s0>Double blind study</s0>
<s5>19</s5>
</fC03>
<fC03 i1="15" i2="X" l="SPA">
<s0>Estudio doble ciego</s0>
<s5>19</s5>
</fC03>
<fC03 i1="16" i2="X" l="FRE">
<s0>Essai clinique</s0>
<s5>20</s5>
</fC03>
<fC03 i1="16" i2="X" l="ENG">
<s0>Clinical trial</s0>
<s5>20</s5>
</fC03>
<fC03 i1="16" i2="X" l="SPA">
<s0>Ensayo clínico</s0>
<s5>20</s5>
</fC03>
<fC03 i1="17" i2="X" l="FRE">
<s0>Antiinflammatoire</s0>
<s5>21</s5>
</fC03>
<fC03 i1="17" i2="X" l="ENG">
<s0>Antiinflammatory agent</s0>
<s5>21</s5>
</fC03>
<fC03 i1="17" i2="X" l="SPA">
<s0>Antiinflamatorio</s0>
<s5>21</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Streptococcie</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Streptococcal infection</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Estreptococia</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Bactériose</s0>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Bacteriosis</s0>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Bacteriosis</s0>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Infection</s0>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Infection</s0>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Infección</s0>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Appareil circulatoire pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Cardiovascular disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Aparato circulatorio patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Lymphatique pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Lymphatic vessel disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Linfático patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE">
<s0>Glande mammaire pathologie</s0>
<s5>45</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Mammary gland diseases</s0>
<s5>45</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Glándula mamaria patología</s0>
<s5>45</s5>
</fC07>
<fN21>
<s1>313</s1>
</fN21>
</pA>
</standard>
<server>
<NO>PASCAL 98-0480585 INIST</NO>
<ET>Sodium selenite as prophylaxis against erysipelas in secondary lymphedema</ET>
<AU>KASSEROLLER (R.); SCHAUER (A.); MEDEN (H.)</AU>
<AF>Wittlinger's Therapy Center, Alleestrasse 30/6344 Walchsee/Autriche (1 aut.); Department of Pathology, University of Göttingen, Robert-Koch-Str. 40/37075 Göttingen/Allemagne (1 aut.); Department of Gynecology and Obstetrics, University of Göttingen, Robert-Koch-Str. 40/37075 Göttingen/Allemagne (2 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Anticancer research; ISSN 0250-7005; Grèce; Da. 1998; Vol. 18; No. 3C; Pp. 2227-2230; Bibl. 12 ref.</SO>
<LA>Anglais</LA>
<EA>In a randomised, double-blind study, the efficacy of sodium selenite application in combination with physical therapy to relieve congestion was investigated in a cohort of 60 cancer patients with secondary lymph edema, with special reference to the development of the incidence of erysipelas. All of the patients investigated in this study had erysipelas infection of the skin. Selenium was administered in pharmacological doses. The duration of physical therapy was three weeks. Patients were under observation for a further three months. The incidence of erysipelas among our patients was 11%. During the three-week period of intensive treatment, there was not a single case of erysipelas in the treatment group, whereas there was one single case in the placebo group. In the follow-up period (3 months), once again there was not a single case of erysipelas in the treatment group, but 50% of the patients in the placebo group exhibited erysipelas. In spite of higher doses, the selenium level did not rise above normal values. Patients under long-term antibiotic therapy suffered no relapse when the antibiotic therapy was stopped and instead, selenium was administered. It could be shown, in addition, that by administration of a single high-dose of sodium selenite, inflammation could be immediately brought under control.</EA>
<CC>002B02S02</CC>
<FD>Lymphoedème; Complication; Chirurgie; Tumeur maligne; Glande mammaire; Homme; Sodium Sélénite; Voie externe; Voie locale; Etude cohorte; Sélénium; Erysipèle; Prévention; Randomisation; Etude double insu; Essai clinique; Antiinflammatoire</FD>
<FG>Streptococcie; Bactériose; Infection; Appareil circulatoire pathologie; Lymphatique pathologie; Glande mammaire pathologie</FG>
<ED>Lymphedema; Complication; Surgery; Malignant tumor; Mammary gland; Human; Sodium Selenites; Topical administration; Local administration; Cohort study; Selenium; Erysipelas; Prevention; Randomization; Double blind study; Clinical trial; Antiinflammatory agent</ED>
<EG>Streptococcal infection; Bacteriosis; Infection; Cardiovascular disease; Lymphatic vessel disease; Mammary gland diseases</EG>
<GD>Selen</GD>
<SD>Linfedema; Complicación; Cirugía; Tumor maligno; Glándula mamaria; Hombre; Sodio Selenito; Vía externa; Vía local; Estudio cohorte; Selenio; Erisipela; Prevención; Aleatorización; Estudio doble ciego; Ensayo clínico; Antiinflamatorio</SD>
<LO>INIST-19426.354000072626610210</LO>
<ID>98-0480585</ID>
</server>
</inist>
</record>

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