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A randomized, controlled, parallel-group clinical trial comparing multilayer bandaging followed by hosiery versus hosiery alone in the treatment of patients with lymphedema of the limb

Identifieur interne : 000915 ( PascalFrancis/Corpus ); précédent : 000914; suivant : 000916

A randomized, controlled, parallel-group clinical trial comparing multilayer bandaging followed by hosiery versus hosiery alone in the treatment of patients with lymphedema of the limb

Auteurs : Caroline M. A. Badger ; Janet L. Peacock ; Peter S. Mortimer

Source :

RBID : Pascal:00-0454646

Descripteurs français

English descriptors

Abstract

BACKGROUND. Multilayered, low stretch bandages (MLB) combined with exercises, skin care, and manual lymphatic drainage therapy are recommended as an intensive phase of treatment for lymphedema patients. The relative efficacy of each of the components of this comprehensive treatment program have not been determined. This study aimed to compare the effect of multilayer bandaging as an initial phase of lymphedema treatment followed by elastic hosiery versus hosiery alone. METHODS. A randomized, controlled, parallel-group trial was undertaken in the setting of the Lymphedema Clinic, The Royal Marsden Hospital, London. Ninety women with unilateral lymphedema (of the upper or lower limbs) were enrolled in the study. The interventions consisted of 18 days of multilayer bandaging followed by elastic hosiery or hosiery alone, each for a total period of 24 weeks. The main outcome measure was the percentage reduction in excess limb volume. RESULTS. The reduction in limb volume by MLB followed by hosiery was approximately double that from hosiery alone and was sustained over the 24-week period. The mean overall percentage reduction at 24 weeks was 31% (n = 32) for MLB versus 15.8% (n = 46) for hosiery alone, for a mean difference of 15.2% (95% confidence interval, 6.2-24.2) (P = 0.001). CONCLUSIONS. Multilayer bandaging as an initial phase of treatment for lymphedema patients, followed by hosiery, achieves greater and more sustained limb volume reduction than hosiery alone.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0008-543X
A02 01      @0 CANCAR
A03   1    @0 Cancer
A05       @2 88
A06       @2 12
A08 01  1  ENG  @1 A randomized, controlled, parallel-group clinical trial comparing multilayer bandaging followed by hosiery versus hosiery alone in the treatment of patients with lymphedema of the limb
A11 01  1    @1 BADGER (Caroline M. A.)
A11 02  1    @1 PEACOCK (Janet L.)
A11 03  1    @1 MORTIMER (Peter S.)
A14 01      @1 Institute of Cancer Research, Royal Marsden Hospital @2 London @3 GBR @Z 1 aut.
A14 02      @1 Department of Public Health Sciences, St. George's Hospital Medical School @2 London @3 GBR @Z 2 aut.
A14 03      @1 Lymphedema Clinic, Royal Marsden Hospital @2 Sutton, Surrey @3 GBR @Z 3 aut.
A20       @1 2832-2837
A21       @1 2000
A23 01      @0 ENG
A43 01      @1 INIST @2 2701 @5 354000091349260230
A44       @0 0000 @1 © 2000 INIST-CNRS. All rights reserved.
A45       @0 21 ref.
A47 01  1    @0 00-0454646
A60       @1 P
A61       @0 A
A64 01  1    @0 Cancer
A66 01      @0 USA
C01 01    ENG  @0 BACKGROUND. Multilayered, low stretch bandages (MLB) combined with exercises, skin care, and manual lymphatic drainage therapy are recommended as an intensive phase of treatment for lymphedema patients. The relative efficacy of each of the components of this comprehensive treatment program have not been determined. This study aimed to compare the effect of multilayer bandaging as an initial phase of lymphedema treatment followed by elastic hosiery versus hosiery alone. METHODS. A randomized, controlled, parallel-group trial was undertaken in the setting of the Lymphedema Clinic, The Royal Marsden Hospital, London. Ninety women with unilateral lymphedema (of the upper or lower limbs) were enrolled in the study. The interventions consisted of 18 days of multilayer bandaging followed by elastic hosiery or hosiery alone, each for a total period of 24 weeks. The main outcome measure was the percentage reduction in excess limb volume. RESULTS. The reduction in limb volume by MLB followed by hosiery was approximately double that from hosiery alone and was sustained over the 24-week period. The mean overall percentage reduction at 24 weeks was 31% (n = 32) for MLB versus 15.8% (n = 46) for hosiery alone, for a mean difference of 15.2% (95% confidence interval, 6.2-24.2) (P = 0.001). CONCLUSIONS. Multilayer bandaging as an initial phase of treatment for lymphedema patients, followed by hosiery, achieves greater and more sustained limb volume reduction than hosiery alone.
C02 01  X    @0 002B12B04
C03 01  X  FRE  @0 Lymphoedème @5 01
C03 01  X  ENG  @0 Lymphedema @5 01
C03 01  X  SPA  @0 Linfedema @5 01
C03 02  X  FRE  @0 Membre @5 02
C03 02  X  ENG  @0 Limb @5 02
C03 02  X  SPA  @0 Miembro @5 02
C03 03  X  FRE  @0 Bandage compressif @5 04
C03 03  X  ENG  @0 Compressive bandage @5 04
C03 03  X  SPA  @0 Vendaje compresivo @5 04
C03 04  X  FRE  @0 Bas varice @5 05
C03 04  X  ENG  @0 Elastic stocking @5 05
C03 04  X  SPA  @0 Media várice @5 05
C03 05  X  FRE  @0 Association @5 06
C03 05  X  ENG  @0 Association @5 06
C03 05  X  SPA  @0 Asociación @5 06
C03 06  X  FRE  @0 Traitement @5 07
C03 06  X  ENG  @0 Treatment @5 07
C03 06  X  SPA  @0 Tratamiento @5 07
C03 07  X  FRE  @0 Essai thérapeutique contrôlé @5 08
C03 07  X  ENG  @0 Controlled therapeutic trial @5 08
C03 07  X  SPA  @0 Ensayo terapéutico controlado @5 08
C03 08  X  FRE  @0 Randomisation @5 09
C03 08  X  ENG  @0 Randomization @5 09
C03 08  X  SPA  @0 Aleatorización @5 09
C03 09  X  FRE  @0 Etude comparative @5 10
C03 09  X  ENG  @0 Comparative study @5 10
C03 09  X  SPA  @0 Estudio comparativo @5 10
C03 10  X  FRE  @0 Homme @5 11
C03 10  X  ENG  @0 Human @5 11
C03 10  X  SPA  @0 Hombre @5 11
C07 01  X  FRE  @0 Appareil circulatoire pathologie @5 37
C07 01  X  ENG  @0 Cardiovascular disease @5 37
C07 01  X  SPA  @0 Aparato circulatorio patología @5 37
C07 02  X  FRE  @0 Lymphatique pathologie @5 38
C07 02  X  ENG  @0 Lymphatic vessel disease @5 38
C07 02  X  SPA  @0 Linfático patología @5 38
N21       @1 304

Format Inist (serveur)

NO : PASCAL 00-0454646 INIST
ET : A randomized, controlled, parallel-group clinical trial comparing multilayer bandaging followed by hosiery versus hosiery alone in the treatment of patients with lymphedema of the limb
AU : BADGER (Caroline M. A.); PEACOCK (Janet L.); MORTIMER (Peter S.)
AF : Institute of Cancer Research, Royal Marsden Hospital/London/Royaume-Uni (1 aut.); Department of Public Health Sciences, St. George's Hospital Medical School/London/Royaume-Uni (2 aut.); Lymphedema Clinic, Royal Marsden Hospital/Sutton, Surrey/Royaume-Uni (3 aut.)
DT : Publication en série; Niveau analytique
SO : Cancer; ISSN 0008-543X; Coden CANCAR; Etats-Unis; Da. 2000; Vol. 88; No. 12; Pp. 2832-2837; Bibl. 21 ref.
LA : Anglais
EA : BACKGROUND. Multilayered, low stretch bandages (MLB) combined with exercises, skin care, and manual lymphatic drainage therapy are recommended as an intensive phase of treatment for lymphedema patients. The relative efficacy of each of the components of this comprehensive treatment program have not been determined. This study aimed to compare the effect of multilayer bandaging as an initial phase of lymphedema treatment followed by elastic hosiery versus hosiery alone. METHODS. A randomized, controlled, parallel-group trial was undertaken in the setting of the Lymphedema Clinic, The Royal Marsden Hospital, London. Ninety women with unilateral lymphedema (of the upper or lower limbs) were enrolled in the study. The interventions consisted of 18 days of multilayer bandaging followed by elastic hosiery or hosiery alone, each for a total period of 24 weeks. The main outcome measure was the percentage reduction in excess limb volume. RESULTS. The reduction in limb volume by MLB followed by hosiery was approximately double that from hosiery alone and was sustained over the 24-week period. The mean overall percentage reduction at 24 weeks was 31% (n = 32) for MLB versus 15.8% (n = 46) for hosiery alone, for a mean difference of 15.2% (95% confidence interval, 6.2-24.2) (P = 0.001). CONCLUSIONS. Multilayer bandaging as an initial phase of treatment for lymphedema patients, followed by hosiery, achieves greater and more sustained limb volume reduction than hosiery alone.
CC : 002B12B04
FD : Lymphoedème; Membre; Bandage compressif; Bas varice; Association; Traitement; Essai thérapeutique contrôlé; Randomisation; Etude comparative; Homme
FG : Appareil circulatoire pathologie; Lymphatique pathologie
ED : Lymphedema; Limb; Compressive bandage; Elastic stocking; Association; Treatment; Controlled therapeutic trial; Randomization; Comparative study; Human
EG : Cardiovascular disease; Lymphatic vessel disease
SD : Linfedema; Miembro; Vendaje compresivo; Media várice; Asociación; Tratamiento; Ensayo terapéutico controlado; Aleatorización; Estudio comparativo; Hombre
LO : INIST-2701.354000091349260230
ID : 00-0454646

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Pascal:00-0454646

Le document en format XML

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<div type="abstract" xml:lang="en">BACKGROUND. Multilayered, low stretch bandages (MLB) combined with exercises, skin care, and manual lymphatic drainage therapy are recommended as an intensive phase of treatment for lymphedema patients. The relative efficacy of each of the components of this comprehensive treatment program have not been determined. This study aimed to compare the effect of multilayer bandaging as an initial phase of lymphedema treatment followed by elastic hosiery versus hosiery alone. METHODS. A randomized, controlled, parallel-group trial was undertaken in the setting of the Lymphedema Clinic, The Royal Marsden Hospital, London. Ninety women with unilateral lymphedema (of the upper or lower limbs) were enrolled in the study. The interventions consisted of 18 days of multilayer bandaging followed by elastic hosiery or hosiery alone, each for a total period of 24 weeks. The main outcome measure was the percentage reduction in excess limb volume. RESULTS. The reduction in limb volume by MLB followed by hosiery was approximately double that from hosiery alone and was sustained over the 24-week period. The mean overall percentage reduction at 24 weeks was 31% (n = 32) for MLB versus 15.8% (n = 46) for hosiery alone, for a mean difference of 15.2% (95% confidence interval, 6.2-24.2) (P = 0.001). CONCLUSIONS. Multilayer bandaging as an initial phase of treatment for lymphedema patients, followed by hosiery, achieves greater and more sustained limb volume reduction than hosiery alone.</div>
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<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Cardiovascular disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Aparato circulatorio patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Lymphatique pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Lymphatic vessel disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Linfático patología</s0>
<s5>38</s5>
</fC07>
<fN21>
<s1>304</s1>
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<NO>PASCAL 00-0454646 INIST</NO>
<ET>A randomized, controlled, parallel-group clinical trial comparing multilayer bandaging followed by hosiery versus hosiery alone in the treatment of patients with lymphedema of the limb</ET>
<AU>BADGER (Caroline M. A.); PEACOCK (Janet L.); MORTIMER (Peter S.)</AU>
<AF>Institute of Cancer Research, Royal Marsden Hospital/London/Royaume-Uni (1 aut.); Department of Public Health Sciences, St. George's Hospital Medical School/London/Royaume-Uni (2 aut.); Lymphedema Clinic, Royal Marsden Hospital/Sutton, Surrey/Royaume-Uni (3 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Cancer; ISSN 0008-543X; Coden CANCAR; Etats-Unis; Da. 2000; Vol. 88; No. 12; Pp. 2832-2837; Bibl. 21 ref.</SO>
<LA>Anglais</LA>
<EA>BACKGROUND. Multilayered, low stretch bandages (MLB) combined with exercises, skin care, and manual lymphatic drainage therapy are recommended as an intensive phase of treatment for lymphedema patients. The relative efficacy of each of the components of this comprehensive treatment program have not been determined. This study aimed to compare the effect of multilayer bandaging as an initial phase of lymphedema treatment followed by elastic hosiery versus hosiery alone. METHODS. A randomized, controlled, parallel-group trial was undertaken in the setting of the Lymphedema Clinic, The Royal Marsden Hospital, London. Ninety women with unilateral lymphedema (of the upper or lower limbs) were enrolled in the study. The interventions consisted of 18 days of multilayer bandaging followed by elastic hosiery or hosiery alone, each for a total period of 24 weeks. The main outcome measure was the percentage reduction in excess limb volume. RESULTS. The reduction in limb volume by MLB followed by hosiery was approximately double that from hosiery alone and was sustained over the 24-week period. The mean overall percentage reduction at 24 weeks was 31% (n = 32) for MLB versus 15.8% (n = 46) for hosiery alone, for a mean difference of 15.2% (95% confidence interval, 6.2-24.2) (P = 0.001). CONCLUSIONS. Multilayer bandaging as an initial phase of treatment for lymphedema patients, followed by hosiery, achieves greater and more sustained limb volume reduction than hosiery alone.</EA>
<CC>002B12B04</CC>
<FD>Lymphoedème; Membre; Bandage compressif; Bas varice; Association; Traitement; Essai thérapeutique contrôlé; Randomisation; Etude comparative; Homme</FD>
<FG>Appareil circulatoire pathologie; Lymphatique pathologie</FG>
<ED>Lymphedema; Limb; Compressive bandage; Elastic stocking; Association; Treatment; Controlled therapeutic trial; Randomization; Comparative study; Human</ED>
<EG>Cardiovascular disease; Lymphatic vessel disease</EG>
<SD>Linfedema; Miembro; Vendaje compresivo; Media várice; Asociación; Tratamiento; Ensayo terapéutico controlado; Aleatorización; Estudio comparativo; Hombre</SD>
<LO>INIST-2701.354000091349260230</LO>
<ID>00-0454646</ID>
</server>
</inist>
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