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Predictive factors of response to intensive decongestive physiotherapy in upper limb lymphedema after breast cancer treatment : a cohort study

Identifieur interne : 000519 ( PascalFrancis/Corpus ); précédent : 000518; suivant : 000520

Predictive factors of response to intensive decongestive physiotherapy in upper limb lymphedema after breast cancer treatment : a cohort study

Auteurs : Stéphane Vignes ; Raphaël Porcher ; Annick Champagne ; Alain Dupuy

Source :

RBID : Pascal:06-0380746

Descripteurs français

English descriptors

Abstract

Background. Lymphedema is a frequent complication after breast cancer treatment. Reduction of lymphedema volume is obtained during an intensive phase with daily physiotherapy. Response to treatment remains unknown prior treatment. We purposed to analyze predictors of response of lymphedema treatment throughout the first course of physiotherapy. Design. Patients with secondary arm lymphedema were recruited in a single lymphology unit between 2001 and 2004. For each patient, the following data were recorded: characteristics of breast cancer treatment, patient characteristics, body mass index and lymphedema volume prior and at the end of treatment. Results. Three hundred and fifty-seven women (mean age: 53 ± 11 years) were included. Initial excess volume of lymphedema was correlated to body mass index and duration of lymphedema. Mean duration of intensive decongestive therapy was 11.8±3.3 days. Mean excess volume of lymphedema was 1067±622 ml prior treatment and 663±366 ml after treatment (p<0.001), percentage of excess volume of lymphedema was 59±34% and 36±19%, respectively. Absolute volume reduction was 404±33 ml (p<0.001). Body mass index and duration of lymphedema before treatment were the two predictors of absolute reduction of lymphedema volume. Higher was the body mass index or the duration of lymphedema, more important was the absolute reduction of lymphedema volume. Mean relative percentage of volume reduction was 36±14% whatever mass index or the duration of lymphedema was. Conclusion. Duration of lymphedema from cancer treatment and body mass index were the only two predictors of absolute reduction of lymphedema volume after intensive decongestive physiotherapy. For all patients this latter treatment is highly effective in management of secondary upper limb lymphedema after breast cancer.

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A08 01  1  ENG  @1 Predictive factors of response to intensive decongestive physiotherapy in upper limb lymphedema after breast cancer treatment : a cohort study
A11 01  1    @1 VIGNES (Stéphane)
A11 02  1    @1 PORCHER (Raphaël)
A11 03  1    @1 CHAMPAGNE (Annick)
A11 04  1    @1 DUPUY (Alain)
A14 01      @1 Department of Lymphology, Hopital Cognacq-Jay @2 Paris @3 FRA @Z 1 aut. @Z 3 aut.
A14 02      @1 Department of Biostatistics and Medical Informatics, Hopital Saint-Louis AP-HP, Université Paris 7 @2 Paris @3 FRA @Z 2 aut.
A14 03      @1 Department of Dermatology 2, Hopital Saint Louis AP-HP @2 Paris @3 FRA @Z 4 aut.
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A44       @0 0000 @1 © 2006 INIST-CNRS. All rights reserved.
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C01 01    ENG  @0 Background. Lymphedema is a frequent complication after breast cancer treatment. Reduction of lymphedema volume is obtained during an intensive phase with daily physiotherapy. Response to treatment remains unknown prior treatment. We purposed to analyze predictors of response of lymphedema treatment throughout the first course of physiotherapy. Design. Patients with secondary arm lymphedema were recruited in a single lymphology unit between 2001 and 2004. For each patient, the following data were recorded: characteristics of breast cancer treatment, patient characteristics, body mass index and lymphedema volume prior and at the end of treatment. Results. Three hundred and fifty-seven women (mean age: 53 ± 11 years) were included. Initial excess volume of lymphedema was correlated to body mass index and duration of lymphedema. Mean duration of intensive decongestive therapy was 11.8±3.3 days. Mean excess volume of lymphedema was 1067±622 ml prior treatment and 663±366 ml after treatment (p<0.001), percentage of excess volume of lymphedema was 59±34% and 36±19%, respectively. Absolute volume reduction was 404±33 ml (p<0.001). Body mass index and duration of lymphedema before treatment were the two predictors of absolute reduction of lymphedema volume. Higher was the body mass index or the duration of lymphedema, more important was the absolute reduction of lymphedema volume. Mean relative percentage of volume reduction was 36±14% whatever mass index or the duration of lymphedema was. Conclusion. Duration of lymphedema from cancer treatment and body mass index were the only two predictors of absolute reduction of lymphedema volume after intensive decongestive physiotherapy. For all patients this latter treatment is highly effective in management of secondary upper limb lymphedema after breast cancer.
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Format Inist (serveur)

NO : PASCAL 06-0380746 INIST
ET : Predictive factors of response to intensive decongestive physiotherapy in upper limb lymphedema after breast cancer treatment : a cohort study
AU : VIGNES (Stéphane); PORCHER (Raphaël); CHAMPAGNE (Annick); DUPUY (Alain)
AF : Department of Lymphology, Hopital Cognacq-Jay/Paris/France (1 aut., 3 aut.); Department of Biostatistics and Medical Informatics, Hopital Saint-Louis AP-HP, Université Paris 7/Paris/France (2 aut.); Department of Dermatology 2, Hopital Saint Louis AP-HP/Paris/France (4 aut.)
DT : Publication en série; Niveau analytique
SO : Breast cancer research and treatment; ISSN 0167-6806; Coden BCTRD6; Pays-Bas; Da. 2006; Vol. 98; No. 1; Pp. 1-6; Bibl. 23 ref.
LA : Anglais
EA : Background. Lymphedema is a frequent complication after breast cancer treatment. Reduction of lymphedema volume is obtained during an intensive phase with daily physiotherapy. Response to treatment remains unknown prior treatment. We purposed to analyze predictors of response of lymphedema treatment throughout the first course of physiotherapy. Design. Patients with secondary arm lymphedema were recruited in a single lymphology unit between 2001 and 2004. For each patient, the following data were recorded: characteristics of breast cancer treatment, patient characteristics, body mass index and lymphedema volume prior and at the end of treatment. Results. Three hundred and fifty-seven women (mean age: 53 ± 11 years) were included. Initial excess volume of lymphedema was correlated to body mass index and duration of lymphedema. Mean duration of intensive decongestive therapy was 11.8±3.3 days. Mean excess volume of lymphedema was 1067±622 ml prior treatment and 663±366 ml after treatment (p<0.001), percentage of excess volume of lymphedema was 59±34% and 36±19%, respectively. Absolute volume reduction was 404±33 ml (p<0.001). Body mass index and duration of lymphedema before treatment were the two predictors of absolute reduction of lymphedema volume. Higher was the body mass index or the duration of lymphedema, more important was the absolute reduction of lymphedema volume. Mean relative percentage of volume reduction was 36±14% whatever mass index or the duration of lymphedema was. Conclusion. Duration of lymphedema from cancer treatment and body mass index were the only two predictors of absolute reduction of lymphedema volume after intensive decongestive physiotherapy. For all patients this latter treatment is highly effective in management of secondary upper limb lymphedema after breast cancer.
CC : 002B20E02; 002B12B04
FD : Facteur prédictif; Physiothérapie; Membre supérieur; Lymphoedème; Traitement; Santé publique; Homme; Etude cohorte; Cancer sein
FG : Appareil circulatoire pathologie; Lymphatique pathologie; Tumeur maligne; Glande mammaire pathologie
ED : Predictive factor; Physiotherapy; Upper limb; Lymphedema; Treatment; Public health; Human; Cohort study; Breast cancer
EG : Cardiovascular disease; Lymphatic vessel disease; Malignant tumor; Mammary gland diseases
SD : Factor predictivo; Fisioterapia; Miembro superior; Linfedema; Tratamiento; Salud pública; Hombre; Estudio cohorte; Cáncer pecho
LO : INIST-20699.354000157063290010
ID : 06-0380746

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<div type="abstract" xml:lang="en">Background. Lymphedema is a frequent complication after breast cancer treatment. Reduction of lymphedema volume is obtained during an intensive phase with daily physiotherapy. Response to treatment remains unknown prior treatment. We purposed to analyze predictors of response of lymphedema treatment throughout the first course of physiotherapy. Design. Patients with secondary arm lymphedema were recruited in a single lymphology unit between 2001 and 2004. For each patient, the following data were recorded: characteristics of breast cancer treatment, patient characteristics, body mass index and lymphedema volume prior and at the end of treatment. Results. Three hundred and fifty-seven women (mean age: 53 ± 11 years) were included. Initial excess volume of lymphedema was correlated to body mass index and duration of lymphedema. Mean duration of intensive decongestive therapy was 11.8±3.3 days. Mean excess volume of lymphedema was 1067±622 ml prior treatment and 663±366 ml after treatment (p<0.001), percentage of excess volume of lymphedema was 59±34% and 36±19%, respectively. Absolute volume reduction was 404±33 ml (p<0.001). Body mass index and duration of lymphedema before treatment were the two predictors of absolute reduction of lymphedema volume. Higher was the body mass index or the duration of lymphedema, more important was the absolute reduction of lymphedema volume. Mean relative percentage of volume reduction was 36±14% whatever mass index or the duration of lymphedema was. Conclusion. Duration of lymphedema from cancer treatment and body mass index were the only two predictors of absolute reduction of lymphedema volume after intensive decongestive physiotherapy. For all patients this latter treatment is highly effective in management of secondary upper limb lymphedema after breast cancer.</div>
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</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Tratamiento</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Santé publique</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Public health</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Salud pública</s0>
<s5>06</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Homme</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Human</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Hombre</s0>
<s5>07</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE">
<s0>Etude cohorte</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG">
<s0>Cohort study</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA">
<s0>Estudio cohorte</s0>
<s5>08</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE">
<s0>Cancer sein</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG">
<s0>Breast cancer</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA">
<s0>Cáncer pecho</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Appareil circulatoire pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Cardiovascular disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Aparato circulatorio patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Lymphatique pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Lymphatic vessel disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Linfático patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Tumeur maligne</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Malignant tumor</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Tumor maligno</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Glande mammaire pathologie</s0>
<s2>NM</s2>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Mammary gland diseases</s0>
<s2>NM</s2>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Glándula mamaria patología</s0>
<s2>NM</s2>
<s5>40</s5>
</fC07>
<fN21>
<s1>254</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
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<server>
<NO>PASCAL 06-0380746 INIST</NO>
<ET>Predictive factors of response to intensive decongestive physiotherapy in upper limb lymphedema after breast cancer treatment : a cohort study</ET>
<AU>VIGNES (Stéphane); PORCHER (Raphaël); CHAMPAGNE (Annick); DUPUY (Alain)</AU>
<AF>Department of Lymphology, Hopital Cognacq-Jay/Paris/France (1 aut., 3 aut.); Department of Biostatistics and Medical Informatics, Hopital Saint-Louis AP-HP, Université Paris 7/Paris/France (2 aut.); Department of Dermatology 2, Hopital Saint Louis AP-HP/Paris/France (4 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Breast cancer research and treatment; ISSN 0167-6806; Coden BCTRD6; Pays-Bas; Da. 2006; Vol. 98; No. 1; Pp. 1-6; Bibl. 23 ref.</SO>
<LA>Anglais</LA>
<EA>Background. Lymphedema is a frequent complication after breast cancer treatment. Reduction of lymphedema volume is obtained during an intensive phase with daily physiotherapy. Response to treatment remains unknown prior treatment. We purposed to analyze predictors of response of lymphedema treatment throughout the first course of physiotherapy. Design. Patients with secondary arm lymphedema were recruited in a single lymphology unit between 2001 and 2004. For each patient, the following data were recorded: characteristics of breast cancer treatment, patient characteristics, body mass index and lymphedema volume prior and at the end of treatment. Results. Three hundred and fifty-seven women (mean age: 53 ± 11 years) were included. Initial excess volume of lymphedema was correlated to body mass index and duration of lymphedema. Mean duration of intensive decongestive therapy was 11.8±3.3 days. Mean excess volume of lymphedema was 1067±622 ml prior treatment and 663±366 ml after treatment (p<0.001), percentage of excess volume of lymphedema was 59±34% and 36±19%, respectively. Absolute volume reduction was 404±33 ml (p<0.001). Body mass index and duration of lymphedema before treatment were the two predictors of absolute reduction of lymphedema volume. Higher was the body mass index or the duration of lymphedema, more important was the absolute reduction of lymphedema volume. Mean relative percentage of volume reduction was 36±14% whatever mass index or the duration of lymphedema was. Conclusion. Duration of lymphedema from cancer treatment and body mass index were the only two predictors of absolute reduction of lymphedema volume after intensive decongestive physiotherapy. For all patients this latter treatment is highly effective in management of secondary upper limb lymphedema after breast cancer.</EA>
<CC>002B20E02; 002B12B04</CC>
<FD>Facteur prédictif; Physiothérapie; Membre supérieur; Lymphoedème; Traitement; Santé publique; Homme; Etude cohorte; Cancer sein</FD>
<FG>Appareil circulatoire pathologie; Lymphatique pathologie; Tumeur maligne; Glande mammaire pathologie</FG>
<ED>Predictive factor; Physiotherapy; Upper limb; Lymphedema; Treatment; Public health; Human; Cohort study; Breast cancer</ED>
<EG>Cardiovascular disease; Lymphatic vessel disease; Malignant tumor; Mammary gland diseases</EG>
<SD>Factor predictivo; Fisioterapia; Miembro superior; Linfedema; Tratamiento; Salud pública; Hombre; Estudio cohorte; Cáncer pecho</SD>
<LO>INIST-20699.354000157063290010</LO>
<ID>06-0380746</ID>
</server>
</inist>
</record>

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