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A case of primary cutaneous nasal type NK/T-cell lymphoma and review of the literature

Identifieur interne : 000497 ( PascalFrancis/Corpus ); précédent : 000496; suivant : 000498

A case of primary cutaneous nasal type NK/T-cell lymphoma and review of the literature

Auteurs : J. Stokkermans-Dubois ; T. Jouary ; B. Vergier ; M. M. Delaunay ; A. Taieb

Source :

RBID : Pascal:07-0047696

Descripteurs français

English descriptors

Abstract

Introduction: Cutaneous T-cell lymphoma subtypes are now better identified thanks to progress in immunohistochemistry. This article describes a new case of primary cutaneous natural killer/T-cell lymphoma of nasal type (NKTL-NT) and reviews 18 other cases of this rare neoplasm. Case Report: A 79-year-old man presented with a 3-cm nodular tumor of the left leg occurring on a primary chronic lymphedema of the legs. The lesion was CD56+, CD3 intracytoplasmic+, CD45+ and Epstein-Barr virus+. A comprehensive workup including CTscan and bone marrow biopsy was negative and a diagnosis of NKTL-NT with a primary cutaneous involvement was made. The patient was free of disease under multi-agent chemotherapy after 24 months of follow-up. Discussion: After reviewing 18 other cases of primary cutaneous NKTL-NT, we conclude that the prognosis of these lymphomas is usually poor. However, limited cutaneous forms have a longer median survival than extracutaneous variants.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A11 03  1    @1 VERGIER (B.)
A11 04  1    @1 DELAUNAY (M. M.)
A11 05  1    @1 TAIEB (A.)
A14 01      @1 Skin and Cancer Unit, Department of Dermatology, Saint André Hospital @2 Bordeaux @3 FRA @Z 1 aut. @Z 2 aut. @Z 4 aut. @Z 5 aut.
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C01 01    ENG  @0 Introduction: Cutaneous T-cell lymphoma subtypes are now better identified thanks to progress in immunohistochemistry. This article describes a new case of primary cutaneous natural killer/T-cell lymphoma of nasal type (NKTL-NT) and reviews 18 other cases of this rare neoplasm. Case Report: A 79-year-old man presented with a 3-cm nodular tumor of the left leg occurring on a primary chronic lymphedema of the legs. The lesion was CD56+, CD3 intracytoplasmic+, CD45+ and Epstein-Barr virus+. A comprehensive workup including CTscan and bone marrow biopsy was negative and a diagnosis of NKTL-NT with a primary cutaneous involvement was made. The patient was free of disease under multi-agent chemotherapy after 24 months of follow-up. Discussion: After reviewing 18 other cases of primary cutaneous NKTL-NT, we conclude that the prognosis of these lymphomas is usually poor. However, limited cutaneous forms have a longer median survival than extracutaneous variants.
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Format Inist (serveur)

NO : PASCAL 07-0047696 INIST
ET : A case of primary cutaneous nasal type NK/T-cell lymphoma and review of the literature
AU : STOKKERMANS-DUBOIS (J.); JOUARY (T.); VERGIER (B.); DELAUNAY (M. M.); TAIEB (A.)
AF : Skin and Cancer Unit, Department of Dermatology, Saint André Hospital/Bordeaux/France (1 aut., 2 aut., 4 aut., 5 aut.); Department of Pathology, Haut-Lévêque Hospital/Pessac/France (3 aut.)
DT : Publication en série; Etude de cas, cas et faits cliniques; Niveau analytique
SO : Dermatology : (Basel); ISSN 1018-8665; Suisse; Da. 2006; Vol. 213; No. 4; Pp. 345-349; Bibl. 12 ref.
LA : Anglais
EA : Introduction: Cutaneous T-cell lymphoma subtypes are now better identified thanks to progress in immunohistochemistry. This article describes a new case of primary cutaneous natural killer/T-cell lymphoma of nasal type (NKTL-NT) and reviews 18 other cases of this rare neoplasm. Case Report: A 79-year-old man presented with a 3-cm nodular tumor of the left leg occurring on a primary chronic lymphedema of the legs. The lesion was CD56+, CD3 intracytoplasmic+, CD45+ and Epstein-Barr virus+. A comprehensive workup including CTscan and bone marrow biopsy was negative and a diagnosis of NKTL-NT with a primary cutaneous involvement was made. The patient was free of disease under multi-agent chemotherapy after 24 months of follow-up. Discussion: After reviewing 18 other cases of primary cutaneous NKTL-NT, we conclude that the prognosis of these lymphomas is usually poor. However, limited cutaneous forms have a longer median survival than extracutaneous variants.
CC : 002B08; 002B19B; 002B06D01
FD : Lymphome; Immunodéficit; Lymphoedème; Primaire; Peau; Nez; Cellule NK; Lymphocyte T; Article synthèse; Dermatologie
FG : Hémopathie maligne; Lymphoprolifératif syndrome; Immunopathologie; Appareil circulatoire pathologie; Lymphatique pathologie
ED : Lymphoma; Immune deficiency; Lymphedema; Primary; Skin; Nose; Natural killer cell; T-Lymphocyte; Review; Dermatology
EG : Malignant hemopathy; Lymphoproliferative syndrome; Immunopathology; Cardiovascular disease; Lymphatic vessel disease
SD : Linfoma; Inmunodeficiencia; Linfedema; Primario; Piel; Nariz; Célula NK; Linfocito T; Artículo síntesis; Dermatología
LO : INIST-4530.354000145098490140
ID : 07-0047696

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Pascal:07-0047696

Le document en format XML

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<s5>40</s5>
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<fC07 i1="04" i2="X" l="ENG">
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<s0>Lymphatique pathologie</s0>
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<s0>Lymphatic vessel disease</s0>
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</fC07>
<fC07 i1="05" i2="X" l="SPA">
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<s1>029</s1>
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<NO>PASCAL 07-0047696 INIST</NO>
<ET>A case of primary cutaneous nasal type NK/T-cell lymphoma and review of the literature</ET>
<AU>STOKKERMANS-DUBOIS (J.); JOUARY (T.); VERGIER (B.); DELAUNAY (M. M.); TAIEB (A.)</AU>
<AF>Skin and Cancer Unit, Department of Dermatology, Saint André Hospital/Bordeaux/France (1 aut., 2 aut., 4 aut., 5 aut.); Department of Pathology, Haut-Lévêque Hospital/Pessac/France (3 aut.)</AF>
<DT>Publication en série; Etude de cas, cas et faits cliniques; Niveau analytique</DT>
<SO>Dermatology : (Basel); ISSN 1018-8665; Suisse; Da. 2006; Vol. 213; No. 4; Pp. 345-349; Bibl. 12 ref.</SO>
<LA>Anglais</LA>
<EA>Introduction: Cutaneous T-cell lymphoma subtypes are now better identified thanks to progress in immunohistochemistry. This article describes a new case of primary cutaneous natural killer/T-cell lymphoma of nasal type (NKTL-NT) and reviews 18 other cases of this rare neoplasm. Case Report: A 79-year-old man presented with a 3-cm nodular tumor of the left leg occurring on a primary chronic lymphedema of the legs. The lesion was CD56+, CD3 intracytoplasmic+, CD45+ and Epstein-Barr virus+. A comprehensive workup including CTscan and bone marrow biopsy was negative and a diagnosis of NKTL-NT with a primary cutaneous involvement was made. The patient was free of disease under multi-agent chemotherapy after 24 months of follow-up. Discussion: After reviewing 18 other cases of primary cutaneous NKTL-NT, we conclude that the prognosis of these lymphomas is usually poor. However, limited cutaneous forms have a longer median survival than extracutaneous variants.</EA>
<CC>002B08; 002B19B; 002B06D01</CC>
<FD>Lymphome; Immunodéficit; Lymphoedème; Primaire; Peau; Nez; Cellule NK; Lymphocyte T; Article synthèse; Dermatologie</FD>
<FG>Hémopathie maligne; Lymphoprolifératif syndrome; Immunopathologie; Appareil circulatoire pathologie; Lymphatique pathologie</FG>
<ED>Lymphoma; Immune deficiency; Lymphedema; Primary; Skin; Nose; Natural killer cell; T-Lymphocyte; Review; Dermatology</ED>
<EG>Malignant hemopathy; Lymphoproliferative syndrome; Immunopathology; Cardiovascular disease; Lymphatic vessel disease</EG>
<SD>Linfoma; Inmunodeficiencia; Linfedema; Primario; Piel; Nariz; Célula NK; Linfocito T; Artículo síntesis; Dermatología</SD>
<LO>INIST-4530.354000145098490140</LO>
<ID>07-0047696</ID>
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