LymphedemaV1, PascalFrancis, Corpus, bibRecord, 000421

Podoconiosis : non-infectious geochemical elephantiasis

Identifieur interne : 000421 ( PascalFrancis/Corpus ); précédent : 000420; suivant : 000422

Podoconiosis : non-infectious geochemical elephantiasis

Auteurs : Gail Davey ; Fasil Tekola ; Melanie J. Newport

Source :

Transactions of the Royal Society of Tropical Medicine and Hygiene [ 0035-9203 ] ; 2007.

RBID : Pascal:08-0030567

Descripteurs français

Pascal (Inist)
- Lymphoedème, Eléphantiasis, Infection, Article synthèse, Homme, Médecine tropicale, Podoconiose.

English descriptors

KwdEn :
- Elephantiasis, Human, Infection, Lymphedema, Podoconiosis, Review, Tropical medicine.

Abstract

This article reviews peer-reviewed publications and book chapters on the history, epidemiology, genetics, ecology, pathogenesis, pathology and management of podoconiosis (endemic non-filarial elephantiasis). Podoconiosis is a non-infectious geochemical elephantiasis caused by exposure of bare feet to irritant alkalic clay soils. It is found in at least 10 countries in tropical Africa, Central America and northwest India, where such soils coexist with high altitude, high seasonal rainfall and low income. Podoconiosis develops in men and women working barefoot on irritant soils, with signs becoming apparent in most patients by the third decade of life. Colloid-sized silicate particles appear to enter through the skin, are taken up into macrophages in the lower limb lymphatics and cause endolymphangitis and obliteration of the lymphatic lumen. Genetic studies provide evidence for high heritability of susceptibility to podoconiosis. The economic burden is significant in affected areas dependent on subsistence farming. Podoconiosis is unique in being an entirely preventable non-communicable disease. Primary prevention entails promoting use of footwear in areas of irritant soil; early stages are reversible given good foot hygiene, but late stages result in considerable economic and social difficulties, and require extended periods of elevation and occasionally nodulectomy.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A14	`01`			`@1 Department of Community Health, Addis Ababa University, P.O. Box 9806 @2 Addis Ababa @3 ETH @Z 1 aut. @Z 2 aut.`
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C01	`01`		`ENG`	@0 This article reviews peer-reviewed publications and book chapters on the history, epidemiology, genetics, ecology, pathogenesis, pathology and management of podoconiosis (endemic non-filarial elephantiasis). Podoconiosis is a non-infectious geochemical elephantiasis caused by exposure of bare feet to irritant alkalic clay soils. It is found in at least 10 countries in tropical Africa, Central America and northwest India, where such soils coexist with high altitude, high seasonal rainfall and low income. Podoconiosis develops in men and women working barefoot on irritant soils, with signs becoming apparent in most patients by the third decade of life. Colloid-sized silicate particles appear to enter through the skin, are taken up into macrophages in the lower limb lymphatics and cause endolymphangitis and obliteration of the lymphatic lumen. Genetic studies provide evidence for high heritability of susceptibility to podoconiosis. The economic burden is significant in affected areas dependent on subsistence farming. Podoconiosis is unique in being an entirely preventable non-communicable disease. Primary prevention entails promoting use of footwear in areas of irritant soil; early stages are reversible given good foot hygiene, but late stages result in considerable economic and social difficulties, and require extended periods of elevation and occasionally nodulectomy.
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C03	`03`	`X`	`FRE`	`@0 Infection @5 03`
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C03	`07`	`X`	`FRE`	`@0 Podoconiose @4 CD @5 96`
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C07	`01`	`X`	`FRE`	`@0 Pathologie de l'appareil circulatoire @5 37`
C07	`01`	`X`	`ENG`	`@0 Cardiovascular disease @5 37`
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C07	`02`	`X`	`FRE`	`@0 Pathologie des vaisseaux lymphatiques @5 38`
C07	`02`	`X`	`ENG`	`@0 Lymphatic vessel disease @5 38`
C07	`02`	`X`	`SPA`	`@0 Linfático patología @5 38`
N21				`@1 052`

Format Inist (serveur)

NO :	PASCAL 08-0030567 INIST
ET :	Podoconiosis : non-infectious geochemical elephantiasis
AU :	DAVEY (Gail); TEKOLA (Fasil); NEWPORT (Melanie J.)
AF :	Department of Community Health, Addis Ababa University, P.O. Box 9806/Addis Ababa/Ethiopie (1 aut., 2 aut.); Brighton and Sussex Medical School, University of Sussex/Falmer, Brighton BN1 9PS/Royaume-Uni (3 aut.)
DT :	Publication en série; Niveau analytique
SO :	Transactions of the Royal Society of Tropical Medicine and Hygiene; ISSN 0035-9203; Coden TRSTAZ; Royaume-Uni; Da. 2007; Vol. 101; No. 12; Pp. 1175-1180; Bibl. 3/4 p.
LA :	Anglais
EA :	This article reviews peer-reviewed publications and book chapters on the history, epidemiology, genetics, ecology, pathogenesis, pathology and management of podoconiosis (endemic non-filarial elephantiasis). Podoconiosis is a non-infectious geochemical elephantiasis caused by exposure of bare feet to irritant alkalic clay soils. It is found in at least 10 countries in tropical Africa, Central America and northwest India, where such soils coexist with high altitude, high seasonal rainfall and low income. Podoconiosis develops in men and women working barefoot on irritant soils, with signs becoming apparent in most patients by the third decade of life. Colloid-sized silicate particles appear to enter through the skin, are taken up into macrophages in the lower limb lymphatics and cause endolymphangitis and obliteration of the lymphatic lumen. Genetic studies provide evidence for high heritability of susceptibility to podoconiosis. The economic burden is significant in affected areas dependent on subsistence farming. Podoconiosis is unique in being an entirely preventable non-communicable disease. Primary prevention entails promoting use of footwear in areas of irritant soil; early stages are reversible given good foot hygiene, but late stages result in considerable economic and social difficulties, and require extended periods of elevation and occasionally nodulectomy.
CC :	002B12B04
FD :	Lymphoedème; Eléphantiasis; Infection; Article synthèse; Homme; Médecine tropicale; Podoconiose
FG :	Pathologie de l'appareil circulatoire; Pathologie des vaisseaux lymphatiques
ED :	Lymphedema; Elephantiasis; Infection; Review; Human; Tropical medicine; Podoconiosis
EG :	Cardiovascular disease; Lymphatic vessel disease
SD :	Linfedema; Elefantiasis; Infección; Artículo síntesis; Hombre; Medicina tropical
LO :	INIST-3084.354000162155930050
ID :	08-0030567

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Pascal:08-0030567

Le document en format XML

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<front><div type="abstract" xml:lang="en">This article reviews peer-reviewed publications and book chapters on the history, epidemiology, genetics, ecology, pathogenesis, pathology and management of podoconiosis (endemic non-filarial elephantiasis). Podoconiosis is a non-infectious geochemical elephantiasis caused by exposure of bare feet to irritant alkalic clay soils. It is found in at least 10 countries in tropical Africa, Central America and northwest India, where such soils coexist with high altitude, high seasonal rainfall and low income. Podoconiosis develops in men and women working barefoot on irritant soils, with signs becoming apparent in most patients by the third decade of life. Colloid-sized silicate particles appear to enter through the skin, are taken up into macrophages in the lower limb lymphatics and cause endolymphangitis and obliteration of the lymphatic lumen. Genetic studies provide evidence for high heritability of susceptibility to podoconiosis. The economic burden is significant in affected areas dependent on subsistence farming. Podoconiosis is unique in being an entirely preventable non-communicable disease. Primary prevention entails promoting use of footwear in areas of irritant soil; early stages are reversible given good foot hygiene, but late stages result in considerable economic and social difficulties, and require extended periods of elevation and occasionally nodulectomy.</div>
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<EA>This article reviews peer-reviewed publications and book chapters on the history, epidemiology, genetics, ecology, pathogenesis, pathology and management of podoconiosis (endemic non-filarial elephantiasis). Podoconiosis is a non-infectious geochemical elephantiasis caused by exposure of bare feet to irritant alkalic clay soils. It is found in at least 10 countries in tropical Africa, Central America and northwest India, where such soils coexist with high altitude, high seasonal rainfall and low income. Podoconiosis develops in men and women working barefoot on irritant soils, with signs becoming apparent in most patients by the third decade of life. Colloid-sized silicate particles appear to enter through the skin, are taken up into macrophages in the lower limb lymphatics and cause endolymphangitis and obliteration of the lymphatic lumen. Genetic studies provide evidence for high heritability of susceptibility to podoconiosis. The economic burden is significant in affected areas dependent on subsistence farming. Podoconiosis is unique in being an entirely preventable non-communicable disease. Primary prevention entails promoting use of footwear in areas of irritant soil; early stages are reversible given good foot hygiene, but late stages result in considerable economic and social difficulties, and require extended periods of elevation and occasionally nodulectomy.</EA>
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   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    PascalFrancis
   |étape=   Corpus
   |type=    RBID
   |clé=     Pascal:08-0030567
   |texte=   Podoconiosis : non-infectious geochemical elephantiasis
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Podoconiosis : non-infectious geochemical elephantiasis

Podoconiosis : non-infectious geochemical elephantiasis

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