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Can tissue dielectric constant measurement aid in differentiating lymphoedema from lipoedema in women with swollen legs?

Identifieur interne : 000012 ( PascalFrancis/Corpus ); précédent : 000011; suivant : 000013

Can tissue dielectric constant measurement aid in differentiating lymphoedema from lipoedema in women with swollen legs?

Auteurs : S. Birkballe ; M. R. Jensen ; S. Noerregaard ; F. Gottrup ; T. Karlsmark

Source :

RBID : Pascal:14-0096044

Descripteurs français

English descriptors

Abstract

Background Distinguishing lymphoedema from lipoedema in women with swollen legs can be difficult. Local tissue water content can be quantified using tissue dielectric constant (TDC) measurements. Objectives To examine whether TDC measurements can differentiate untreated lower extremity lymphoedema from lipoedema, and to test interobserver agreement. Methods Thirty-nine women participated in the study; 10 patients with lipoedema (LipP), nine patients with untreated lymphoedema (U-LP), 10 patients with lymphoedema treated with compression bandaging for ≥ 4 weeks (T-LP) and 10 healthy controls. All subjects were measured at three predefined sites (foot, ankle and lower leg). All groups except U-LP were measured by three blinded investigators. Using a handheld device, a 300-MHz electromagnetic wave is transmitted into the skin via a 2.5-mm depth probe. TDC calculated from the reflected wave is directly proportional to tissue water content ranging from 1 (vacuum) to 78.5 (pure water). Results Mean ± SD TDC values for U-LP were 48.8 ± 5-2. TDC values of T-LP, LipP and controls were 34.0 ± 6.6, 295 ± 6.2 and 32.3 ± 5.7, respectively. U-LP had significantly higher TDC values in all measurement sites compared with all other groups (P < 0.001). A cut-off value of 40 for ankle and lower-leg measurements correctly differentiated all U-LP from LipP and controls. Intraclass correlation coefficients were 0.94 for the ankle and the lower leg and 0.63 for the foot. Conclusions TDC values of U-LP were significantly higher than those of T-LP, LipP and controls and may aid in differentiating lymphoedema from lipoedema. Interobserver agreement was high in ankle and lower-leg measurements but low in foot measurements.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A01 01  1    @0 0007-0963
A02 01      @0 BJDEAZ
A03   1    @0 Br. j. dermatol. : (1951)
A05       @2 170
A06       @2 1
A08 01  1  ENG  @1 Can tissue dielectric constant measurement aid in differentiating lymphoedema from lipoedema in women with swollen legs?
A11 01  1    @1 BIRKBALLE (S.)
A11 02  1    @1 JENSEN (M. R.)
A11 03  1    @1 NOERREGAARD (S.)
A11 04  1    @1 GOTTRUP (F.)
A11 05  1    @1 KARLSMARK (T.)
A14 01      @1 Department of Dermatology and Copenhagen Wound Healing Centre, Copenhagen Lymphoedema Centre, Bispebjerg University Hospital, Bispebjerg bakke 23 @2 2400 Copenhagen NV @3 DNK @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut.
A14 02      @1 Department of Clinical Physiology and Nuclear Medicine, Bispebjerg University Hospital, Bispebjerg bakke 23 @2 2400 Copenhagen NV @3 DNK @Z 2 aut.
A20       @1 96-102
A21       @1 2014
A23 01      @0 ENG
A43 01      @1 INIST @2 1043 @5 354000501188280140
A44       @0 0000 @1 © 2014 INIST-CNRS. All rights reserved.
A45       @0 41 ref.
A47 01  1    @0 14-0096044
A60       @1 P
A61       @0 A
A64 01  1    @0 British journal of dermatology : (1951)
A66 01      @0 GBR
C01 01    ENG  @0 Background Distinguishing lymphoedema from lipoedema in women with swollen legs can be difficult. Local tissue water content can be quantified using tissue dielectric constant (TDC) measurements. Objectives To examine whether TDC measurements can differentiate untreated lower extremity lymphoedema from lipoedema, and to test interobserver agreement. Methods Thirty-nine women participated in the study; 10 patients with lipoedema (LipP), nine patients with untreated lymphoedema (U-LP), 10 patients with lymphoedema treated with compression bandaging for ≥ 4 weeks (T-LP) and 10 healthy controls. All subjects were measured at three predefined sites (foot, ankle and lower leg). All groups except U-LP were measured by three blinded investigators. Using a handheld device, a 300-MHz electromagnetic wave is transmitted into the skin via a 2.5-mm depth probe. TDC calculated from the reflected wave is directly proportional to tissue water content ranging from 1 (vacuum) to 78.5 (pure water). Results Mean ± SD TDC values for U-LP were 48.8 ± 5-2. TDC values of T-LP, LipP and controls were 34.0 ± 6.6, 295 ± 6.2 and 32.3 ± 5.7, respectively. U-LP had significantly higher TDC values in all measurement sites compared with all other groups (P < 0.001). A cut-off value of 40 for ankle and lower-leg measurements correctly differentiated all U-LP from LipP and controls. Intraclass correlation coefficients were 0.94 for the ankle and the lower leg and 0.63 for the foot. Conclusions TDC values of U-LP were significantly higher than those of T-LP, LipP and controls and may aid in differentiating lymphoedema from lipoedema. Interobserver agreement was high in ankle and lower-leg measurements but low in foot measurements.
C02 01  X    @0 002B08J
C02 02  X    @0 002B12B04
C03 01  X  FRE  @0 Lymphoedème @5 01
C03 01  X  ENG  @0 Lymphedema @5 01
C03 01  X  SPA  @0 Linfedema @5 01
C03 02  X  FRE  @0 Lipoedème @5 02
C03 02  X  ENG  @0 Lipoedema @5 02
C03 02  X  SPA  @0 Lipoedema @5 02
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C03 03  X  ENG  @0 Measurement @5 04
C03 03  X  SPA  @0 Medida @5 04
C03 04  X  FRE  @0 Tissu @5 07
C03 04  X  ENG  @0 Tissue @5 07
C03 04  X  SPA  @0 Tejido @5 07
C03 05  X  FRE  @0 Femelle @5 08
C03 05  X  ENG  @0 Female @5 08
C03 05  X  SPA  @0 Hembra @5 08
C03 06  X  FRE  @0 Jambe @5 09
C03 06  X  ENG  @0 Leg @5 09
C03 06  X  SPA  @0 Pierna @5 09
C03 07  X  FRE  @0 Homme @5 10
C03 07  X  ENG  @0 Human @5 10
C03 07  X  SPA  @0 Hombre @5 10
C03 08  X  FRE  @0 Femme @5 11
C03 08  X  ENG  @0 Woman @5 11
C03 08  X  SPA  @0 Mujer @5 11
C03 09  X  FRE  @0 Dermatologie @5 13
C03 09  X  ENG  @0 Dermatology @5 13
C03 09  X  SPA  @0 Dermatología @5 13
C07 01  X  FRE  @0 Pathologie de l'appareil circulatoire @5 37
C07 01  X  ENG  @0 Cardiovascular disease @5 37
C07 01  X  SPA  @0 Aparato circulatorio patología @5 37
C07 02  X  FRE  @0 Pathologie des vaisseaux lymphatiques @5 38
C07 02  X  ENG  @0 Lymphatic vessel disease @5 38
C07 02  X  SPA  @0 Linfático patología @5 38
C07 03  X  FRE  @0 Pathologie de la peau @5 39
C07 03  X  ENG  @0 Skin disease @5 39
C07 03  X  SPA  @0 Piel patología @5 39
C07 04  X  FRE  @0 Pathologie du tissu adipeux @5 40
C07 04  X  ENG  @0 Adipose tissue disorders @5 40
C07 04  X  SPA  @0 Tejido adiposo patología @5 40
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Format Inist (serveur)

NO : PASCAL 14-0096044 INIST
ET : Can tissue dielectric constant measurement aid in differentiating lymphoedema from lipoedema in women with swollen legs?
AU : BIRKBALLE (S.); JENSEN (M. R.); NOERREGAARD (S.); GOTTRUP (F.); KARLSMARK (T.)
AF : Department of Dermatology and Copenhagen Wound Healing Centre, Copenhagen Lymphoedema Centre, Bispebjerg University Hospital, Bispebjerg bakke 23/2400 Copenhagen NV/Danemark (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.); Department of Clinical Physiology and Nuclear Medicine, Bispebjerg University Hospital, Bispebjerg bakke 23/2400 Copenhagen NV/Danemark (2 aut.)
DT : Publication en série; Niveau analytique
SO : British journal of dermatology : (1951); ISSN 0007-0963; Coden BJDEAZ; Royaume-Uni; Da. 2014; Vol. 170; No. 1; Pp. 96-102; Bibl. 41 ref.
LA : Anglais
EA : Background Distinguishing lymphoedema from lipoedema in women with swollen legs can be difficult. Local tissue water content can be quantified using tissue dielectric constant (TDC) measurements. Objectives To examine whether TDC measurements can differentiate untreated lower extremity lymphoedema from lipoedema, and to test interobserver agreement. Methods Thirty-nine women participated in the study; 10 patients with lipoedema (LipP), nine patients with untreated lymphoedema (U-LP), 10 patients with lymphoedema treated with compression bandaging for ≥ 4 weeks (T-LP) and 10 healthy controls. All subjects were measured at three predefined sites (foot, ankle and lower leg). All groups except U-LP were measured by three blinded investigators. Using a handheld device, a 300-MHz electromagnetic wave is transmitted into the skin via a 2.5-mm depth probe. TDC calculated from the reflected wave is directly proportional to tissue water content ranging from 1 (vacuum) to 78.5 (pure water). Results Mean ± SD TDC values for U-LP were 48.8 ± 5-2. TDC values of T-LP, LipP and controls were 34.0 ± 6.6, 295 ± 6.2 and 32.3 ± 5.7, respectively. U-LP had significantly higher TDC values in all measurement sites compared with all other groups (P < 0.001). A cut-off value of 40 for ankle and lower-leg measurements correctly differentiated all U-LP from LipP and controls. Intraclass correlation coefficients were 0.94 for the ankle and the lower leg and 0.63 for the foot. Conclusions TDC values of U-LP were significantly higher than those of T-LP, LipP and controls and may aid in differentiating lymphoedema from lipoedema. Interobserver agreement was high in ankle and lower-leg measurements but low in foot measurements.
CC : 002B08J; 002B12B04
FD : Lymphoedème; Lipoedème; Mesure; Tissu; Femelle; Jambe; Homme; Femme; Dermatologie
FG : Pathologie de l'appareil circulatoire; Pathologie des vaisseaux lymphatiques; Pathologie de la peau; Pathologie du tissu adipeux
ED : Lymphedema; Lipoedema; Measurement; Tissue; Female; Leg; Human; Woman; Dermatology
EG : Cardiovascular disease; Lymphatic vessel disease; Skin disease; Adipose tissue disorders
SD : Linfedema; Lipoedema; Medida; Tejido; Hembra; Pierna; Hombre; Mujer; Dermatología
LO : INIST-1043.354000501188280140
ID : 14-0096044

Links to Exploration step

Pascal:14-0096044

Le document en format XML

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<div type="abstract" xml:lang="en">Background Distinguishing lymphoedema from lipoedema in women with swollen legs can be difficult. Local tissue water content can be quantified using tissue dielectric constant (TDC) measurements. Objectives To examine whether TDC measurements can differentiate untreated lower extremity lymphoedema from lipoedema, and to test interobserver agreement. Methods Thirty-nine women participated in the study; 10 patients with lipoedema (LipP), nine patients with untreated lymphoedema (U-LP), 10 patients with lymphoedema treated with compression bandaging for ≥ 4 weeks (T-LP) and 10 healthy controls. All subjects were measured at three predefined sites (foot, ankle and lower leg). All groups except U-LP were measured by three blinded investigators. Using a handheld device, a 300-MHz electromagnetic wave is transmitted into the skin via a 2.5-mm depth probe. TDC calculated from the reflected wave is directly proportional to tissue water content ranging from 1 (vacuum) to 78.5 (pure water). Results Mean ± SD TDC values for U-LP were 48.8 ± 5-2. TDC values of T-LP, LipP and controls were 34.0 ± 6.6, 295 ± 6.2 and 32.3 ± 5.7, respectively. U-LP had significantly higher TDC values in all measurement sites compared with all other groups (P < 0.001). A cut-off value of 40 for ankle and lower-leg measurements correctly differentiated all U-LP from LipP and controls. Intraclass correlation coefficients were 0.94 for the ankle and the lower leg and 0.63 for the foot. Conclusions TDC values of U-LP were significantly higher than those of T-LP, LipP and controls and may aid in differentiating lymphoedema from lipoedema. Interobserver agreement was high in ankle and lower-leg measurements but low in foot measurements.</div>
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</fA66>
<fC01 i1="01" l="ENG">
<s0>Background Distinguishing lymphoedema from lipoedema in women with swollen legs can be difficult. Local tissue water content can be quantified using tissue dielectric constant (TDC) measurements. Objectives To examine whether TDC measurements can differentiate untreated lower extremity lymphoedema from lipoedema, and to test interobserver agreement. Methods Thirty-nine women participated in the study; 10 patients with lipoedema (LipP), nine patients with untreated lymphoedema (U-LP), 10 patients with lymphoedema treated with compression bandaging for ≥ 4 weeks (T-LP) and 10 healthy controls. All subjects were measured at three predefined sites (foot, ankle and lower leg). All groups except U-LP were measured by three blinded investigators. Using a handheld device, a 300-MHz electromagnetic wave is transmitted into the skin via a 2.5-mm depth probe. TDC calculated from the reflected wave is directly proportional to tissue water content ranging from 1 (vacuum) to 78.5 (pure water). Results Mean ± SD TDC values for U-LP were 48.8 ± 5-2. TDC values of T-LP, LipP and controls were 34.0 ± 6.6, 295 ± 6.2 and 32.3 ± 5.7, respectively. U-LP had significantly higher TDC values in all measurement sites compared with all other groups (P < 0.001). A cut-off value of 40 for ankle and lower-leg measurements correctly differentiated all U-LP from LipP and controls. Intraclass correlation coefficients were 0.94 for the ankle and the lower leg and 0.63 for the foot. Conclusions TDC values of U-LP were significantly higher than those of T-LP, LipP and controls and may aid in differentiating lymphoedema from lipoedema. Interobserver agreement was high in ankle and lower-leg measurements but low in foot measurements.</s0>
</fC01>
<fC02 i1="01" i2="X">
<s0>002B08J</s0>
</fC02>
<fC02 i1="02" i2="X">
<s0>002B12B04</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE">
<s0>Lymphoedème</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG">
<s0>Lymphedema</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA">
<s0>Linfedema</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE">
<s0>Lipoedème</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG">
<s0>Lipoedema</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Lipoedema</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Mesure</s0>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Measurement</s0>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Medida</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Tissu</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Tissue</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Tejido</s0>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Femelle</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Female</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Hembra</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Jambe</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Leg</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Pierna</s0>
<s5>09</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Homme</s0>
<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Human</s0>
<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Hombre</s0>
<s5>10</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE">
<s0>Femme</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG">
<s0>Woman</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA">
<s0>Mujer</s0>
<s5>11</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE">
<s0>Dermatologie</s0>
<s5>13</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG">
<s0>Dermatology</s0>
<s5>13</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA">
<s0>Dermatología</s0>
<s5>13</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Pathologie de l'appareil circulatoire</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Cardiovascular disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Aparato circulatorio patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Pathologie des vaisseaux lymphatiques</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Lymphatic vessel disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Linfático patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Pathologie de la peau</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Skin disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Piel patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Pathologie du tissu adipeux</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Adipose tissue disorders</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Tejido adiposo patología</s0>
<s5>40</s5>
</fC07>
<fN21>
<s1>132</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
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<fN82>
<s1>OTO</s1>
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<server>
<NO>PASCAL 14-0096044 INIST</NO>
<ET>Can tissue dielectric constant measurement aid in differentiating lymphoedema from lipoedema in women with swollen legs?</ET>
<AU>BIRKBALLE (S.); JENSEN (M. R.); NOERREGAARD (S.); GOTTRUP (F.); KARLSMARK (T.)</AU>
<AF>Department of Dermatology and Copenhagen Wound Healing Centre, Copenhagen Lymphoedema Centre, Bispebjerg University Hospital, Bispebjerg bakke 23/2400 Copenhagen NV/Danemark (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.); Department of Clinical Physiology and Nuclear Medicine, Bispebjerg University Hospital, Bispebjerg bakke 23/2400 Copenhagen NV/Danemark (2 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>British journal of dermatology : (1951); ISSN 0007-0963; Coden BJDEAZ; Royaume-Uni; Da. 2014; Vol. 170; No. 1; Pp. 96-102; Bibl. 41 ref.</SO>
<LA>Anglais</LA>
<EA>Background Distinguishing lymphoedema from lipoedema in women with swollen legs can be difficult. Local tissue water content can be quantified using tissue dielectric constant (TDC) measurements. Objectives To examine whether TDC measurements can differentiate untreated lower extremity lymphoedema from lipoedema, and to test interobserver agreement. Methods Thirty-nine women participated in the study; 10 patients with lipoedema (LipP), nine patients with untreated lymphoedema (U-LP), 10 patients with lymphoedema treated with compression bandaging for ≥ 4 weeks (T-LP) and 10 healthy controls. All subjects were measured at three predefined sites (foot, ankle and lower leg). All groups except U-LP were measured by three blinded investigators. Using a handheld device, a 300-MHz electromagnetic wave is transmitted into the skin via a 2.5-mm depth probe. TDC calculated from the reflected wave is directly proportional to tissue water content ranging from 1 (vacuum) to 78.5 (pure water). Results Mean ± SD TDC values for U-LP were 48.8 ± 5-2. TDC values of T-LP, LipP and controls were 34.0 ± 6.6, 295 ± 6.2 and 32.3 ± 5.7, respectively. U-LP had significantly higher TDC values in all measurement sites compared with all other groups (P < 0.001). A cut-off value of 40 for ankle and lower-leg measurements correctly differentiated all U-LP from LipP and controls. Intraclass correlation coefficients were 0.94 for the ankle and the lower leg and 0.63 for the foot. Conclusions TDC values of U-LP were significantly higher than those of T-LP, LipP and controls and may aid in differentiating lymphoedema from lipoedema. Interobserver agreement was high in ankle and lower-leg measurements but low in foot measurements.</EA>
<CC>002B08J; 002B12B04</CC>
<FD>Lymphoedème; Lipoedème; Mesure; Tissu; Femelle; Jambe; Homme; Femme; Dermatologie</FD>
<FG>Pathologie de l'appareil circulatoire; Pathologie des vaisseaux lymphatiques; Pathologie de la peau; Pathologie du tissu adipeux</FG>
<ED>Lymphedema; Lipoedema; Measurement; Tissue; Female; Leg; Human; Woman; Dermatology</ED>
<EG>Cardiovascular disease; Lymphatic vessel disease; Skin disease; Adipose tissue disorders</EG>
<SD>Linfedema; Lipoedema; Medida; Tejido; Hembra; Pierna; Hombre; Mujer; Dermatología</SD>
<LO>INIST-1043.354000501188280140</LO>
<ID>14-0096044</ID>
</server>
</inist>
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