Chromosomal mapping of two loci affecting filarial worm susceptibility in Aedes aegypti.
Identifieur interne : 00B342 ( Ncbi/Merge ); précédent : 00B341; suivant : 00B343Chromosomal mapping of two loci affecting filarial worm susceptibility in Aedes aegypti.
Auteurs : D W Severson ; A. Mori ; Y. Zhang ; B M ChristensenSource :
- Insect molecular biology [ 0962-1075 ] ; 1994.
Descripteurs français
- KwdFr :
- Aedes (génétique), Aedes (parasitologie), Analyse de détermination du sexe, Animaux, Brugia malayi (pathogénicité), Cartographie chromosomique, Croisements génétiques, Femelle, Filariose lymphatique (transmission), Gènes d'insecte, Humains, Liaison génétique, Marqueurs génétiques, Mâle, Phénotype, Polymorphisme de restriction, Terminologie comme sujet, Vecteurs insectes.
- MESH :
- génétique : Aedes.
- parasitologie : Aedes.
- pathogénicité : Brugia malayi.
- Analyse de détermination du sexe, Animaux, Cartographie chromosomique, Croisements génétiques, Femelle, Filariose lymphatique, Gènes d'insecte, Humains, Liaison génétique, Marqueurs génétiques, Mâle, Phénotype, Polymorphisme de restriction, Terminologie comme sujet, Vecteurs insectes.
English descriptors
- KwdEn :
- Aedes (genetics), Aedes (parasitology), Animals, Brugia malayi (pathogenicity), Chromosome Mapping, Crosses, Genetic, Elephantiasis, Filarial (transmission), Female, Genes, Insect, Genetic Linkage, Genetic Markers, Humans, Insect Vectors, Male, Phenotype, Polymorphism, Restriction Fragment Length, Sex Determination Analysis, Terminology as Topic.
- MESH :
- chemical : Genetic Markers.
- genetics : Aedes.
- parasitology : Aedes.
- pathogenicity : Brugia malayi.
- transmission : Elephantiasis, Filarial.
- Animals, Chromosome Mapping, Crosses, Genetic, Female, Genes, Insect, Genetic Linkage, Humans, Insect Vectors, Male, Phenotype, Polymorphism, Restriction Fragment Length, Sex Determination Analysis, Terminology as Topic.
Abstract
Two quantitative trait loci (QTL) affecting susceptibility of the mosquito Aedes aegypti to the filarial worm parasite Brugia malayi were identified using restriction fragment length polymorphism (RFLP) markers. The first locus, fsb[1,LF178], resides within a 10 cM interval on chromosome 1 and exhibits a recessive effect with respect to susceptibility. The second locus, fsb[2,LF98], resides within a 9 cM interval on chromosome 2 and exhibits an additive effect on susceptibility. Significant epistasis was detected between these loci, although the effect of fsb[2,LF98] was dependent on the genetic background of the mosquito strains. Suggestions for a standard QTL nomenclature are included.
PubMed: 7987523
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The first locus, fsb[1,LF178], resides within a 10 cM interval on chromosome 1 and exhibits a recessive effect with respect to susceptibility. The second locus, fsb[2,LF98], resides within a 9 cM interval on chromosome 2 and exhibits an additive effect on susceptibility. Significant epistasis was detected between these loci, although the effect of fsb[2,LF98] was dependent on the genetic background of the mosquito strains. Suggestions for a standard QTL nomenclature are included.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">7987523</PMID><DateCreated><Year>1995</Year><Month>01</Month><Day>12</Day></DateCreated><DateCompleted><Year>1995</Year><Month>01</Month><Day>12</Day></DateCompleted><DateRevised><Year>2010</Year><Month>11</Month><Day>18</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0962-1075</ISSN><JournalIssue CitedMedium="Print"><Volume>3</Volume><Issue>2</Issue><PubDate><Year>1994</Year><Month>May</Month></PubDate></JournalIssue><Title>Insect molecular biology</Title><ISOAbbreviation>Insect Mol. Biol.</ISOAbbreviation></Journal><ArticleTitle>Chromosomal mapping of two loci affecting filarial worm susceptibility in Aedes aegypti.</ArticleTitle><Pagination><MedlinePgn>67-72</MedlinePgn></Pagination><Abstract><AbstractText>Two quantitative trait loci (QTL) affecting susceptibility of the mosquito Aedes aegypti to the filarial worm parasite Brugia malayi were identified using restriction fragment length polymorphism (RFLP) markers. The first locus, fsb[1,LF178], resides within a 10 cM interval on chromosome 1 and exhibits a recessive effect with respect to susceptibility. The second locus, fsb[2,LF98], resides within a 9 cM interval on chromosome 2 and exhibits an additive effect on susceptibility. Significant epistasis was detected between these loci, although the effect of fsb[2,LF98] was dependent on the genetic background of the mosquito strains. 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Mori</name><name sortKey="Severson, D W" sort="Severson, D W" uniqKey="Severson D" first="D W" last="Severson">D W Severson</name><name sortKey="Zhang, Y" sort="Zhang, Y" uniqKey="Zhang Y" first="Y" last="Zhang">Y. Zhang</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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