General health status of long-term cervical cancer survivors after radiotherapy.
Identifieur interne : 009067 ( Ncbi/Merge ); précédent : 009066; suivant : 009068General health status of long-term cervical cancer survivors after radiotherapy.
Auteurs : Lee Sung Uk ; Kim Young Ae ; Yoon Young-Ho ; Kim Yeon-Joo ; Lim Myong Cheol ; Park Sang-Yoon ; Seo Sang-Soo ; Park Ji Eun ; Kim Joo-Young [Corée du Sud]Source :
- Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] [ 1439-099X ] ; 2017.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Analyse de survie, Chimioradiothérapie, Dosimétrie en radiothérapie, Facteurs de l'âge, Femelle, Humains, Hystérectomie, Intestins (effets des radiations), Lésions radio-induites (étiologie), Qualité de vie (psychologie), Réirradiation, Stade de la tumeur, Sujet âgé, Sujet âgé de 80 ans ou plus, Survivants, Tumeurs du col de l'utérus (), Tumeurs du col de l'utérus (anatomopathologie), Tumeurs du col de l'utérus (mortalité), Tumeurs du col de l'utérus (psychologie), Vessie urinaire (effets des radiations), État de santé, Études de suivi.
- MESH :
- anatomopathologie : Tumeurs du col de l'utérus.
- effets des radiations : Intestins, Vessie urinaire.
- mortalité : Tumeurs du col de l'utérus.
- psychologie : Qualité de vie, Tumeurs du col de l'utérus.
- étiologie : Lésions radio-induites.
- Adulte, Adulte d'âge moyen, Analyse de survie, Chimioradiothérapie, Dosimétrie en radiothérapie, Facteurs de l'âge, Femelle, Humains, Hystérectomie, Réirradiation, Stade de la tumeur, Sujet âgé, Sujet âgé de 80 ans ou plus, Survivants, Tumeurs du col de l'utérus, État de santé, Études de suivi.
English descriptors
- KwdEn :
- Adult, Age Factors, Aged, Aged, 80 and over, Chemoradiotherapy, Female, Follow-Up Studies, Health Status, Humans, Hysterectomy, Intestines (radiation effects), Middle Aged, Neoplasm Staging, Quality of Life (psychology), Radiation Injuries (etiology), Radiotherapy Dosage, Re-Irradiation, Survival Analysis, Survivors, Urinary Bladder (radiation effects), Uterine Cervical Neoplasms (mortality), Uterine Cervical Neoplasms (pathology), Uterine Cervical Neoplasms (psychology), Uterine Cervical Neoplasms (therapy).
- MESH :
- etiology : Radiation Injuries.
- mortality : Uterine Cervical Neoplasms.
- pathology : Uterine Cervical Neoplasms.
- psychology : Quality of Life, Uterine Cervical Neoplasms.
- radiation effects : Intestines, Urinary Bladder.
- therapy : Uterine Cervical Neoplasms.
- Adult, Age Factors, Aged, Aged, 80 and over, Chemoradiotherapy, Female, Follow-Up Studies, Health Status, Humans, Hysterectomy, Middle Aged, Neoplasm Staging, Radiotherapy Dosage, Re-Irradiation, Survival Analysis, Survivors.
Abstract
To evaluate the global health status of long-term cervical cancer survivors (LCCS) who survived for more than 4 years after curative radiation treatment (RT).
DOI: 10.1007/s00066-017-1143-8
PubMed: 28492995
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000209
- to stream PubMed, to step Curation: 000209
- to stream PubMed, to step Checkpoint: 000209
Links to Exploration step
pubmed:28492995Le document en format XML
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<term>Age Factors</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Chemoradiotherapy</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Health Status</term>
<term>Humans</term>
<term>Hysterectomy</term>
<term>Intestines (radiation effects)</term>
<term>Middle Aged</term>
<term>Neoplasm Staging</term>
<term>Quality of Life (psychology)</term>
<term>Radiation Injuries (etiology)</term>
<term>Radiotherapy Dosage</term>
<term>Re-Irradiation</term>
<term>Survival Analysis</term>
<term>Survivors</term>
<term>Urinary Bladder (radiation effects)</term>
<term>Uterine Cervical Neoplasms (mortality)</term>
<term>Uterine Cervical Neoplasms (pathology)</term>
<term>Uterine Cervical Neoplasms (psychology)</term>
<term>Uterine Cervical Neoplasms (therapy)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Analyse de survie</term>
<term>Chimioradiothérapie</term>
<term>Dosimétrie en radiothérapie</term>
<term>Facteurs de l'âge</term>
<term>Femelle</term>
<term>Humains</term>
<term>Hystérectomie</term>
<term>Intestins (effets des radiations)</term>
<term>Lésions radio-induites (étiologie)</term>
<term>Qualité de vie (psychologie)</term>
<term>Réirradiation</term>
<term>Stade de la tumeur</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Survivants</term>
<term>Tumeurs du col de l'utérus ()</term>
<term>Tumeurs du col de l'utérus (anatomopathologie)</term>
<term>Tumeurs du col de l'utérus (mortalité)</term>
<term>Tumeurs du col de l'utérus (psychologie)</term>
<term>Vessie urinaire (effets des radiations)</term>
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<term>Études de suivi</term>
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<term>Vessie urinaire</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Radiation Injuries</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Uterine Cervical Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Tumeurs du col de l'utérus</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Uterine Cervical Neoplasms</term>
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<keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Qualité de vie</term>
<term>Tumeurs du col de l'utérus</term>
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<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Quality of Life</term>
<term>Uterine Cervical Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="radiation effects" xml:lang="en"><term>Intestines</term>
<term>Urinary Bladder</term>
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<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Uterine Cervical Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lésions radio-induites</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Age Factors</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Chemoradiotherapy</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Health Status</term>
<term>Humans</term>
<term>Hysterectomy</term>
<term>Middle Aged</term>
<term>Neoplasm Staging</term>
<term>Radiotherapy Dosage</term>
<term>Re-Irradiation</term>
<term>Survival Analysis</term>
<term>Survivors</term>
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<term>Adulte d'âge moyen</term>
<term>Analyse de survie</term>
<term>Chimioradiothérapie</term>
<term>Dosimétrie en radiothérapie</term>
<term>Facteurs de l'âge</term>
<term>Femelle</term>
<term>Humains</term>
<term>Hystérectomie</term>
<term>Réirradiation</term>
<term>Stade de la tumeur</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Survivants</term>
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<front><div type="abstract" xml:lang="en">To evaluate the global health status of long-term cervical cancer survivors (LCCS) who survived for more than 4 years after curative radiation treatment (RT).</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28492995</PMID>
<DateCreated><Year>2017</Year>
<Month>05</Month>
<Day>11</Day>
</DateCreated>
<DateCompleted><Year>2017</Year>
<Month>08</Month>
<Day>17</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>08</Month>
<Day>17</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1439-099X</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>193</Volume>
<Issue>7</Issue>
<PubDate><Year>2017</Year>
<Month>Jul</Month>
</PubDate>
</JournalIssue>
<Title>Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]</Title>
<ISOAbbreviation>Strahlenther Onkol</ISOAbbreviation>
</Journal>
<ArticleTitle>General health status of long-term cervical cancer survivors after radiotherapy.</ArticleTitle>
<Pagination><MedlinePgn>543-551</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1007/s00066-017-1143-8</ELocationID>
<Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To evaluate the global health status of long-term cervical cancer survivors (LCCS) who survived for more than 4 years after curative radiation treatment (RT).</AbstractText>
<AbstractText Label="PATIENTS AND METHODS" NlmCategory="METHODS">Medical records of 562 women treated with RT in our institution between 2003 and 2010 were reviewed. Excluding 259 women who died of disease or were lost to follow-up, disease status and late morbidities were evaluated in 303 LCCS. Quality of life (QoL) was analyzed in 168 LCCS using a questionnaire from the European Organization for the Research and Treatment of Cancer, and the results were compared with an age-matched healthy Korean female population.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Median follow-up was 6.8 years (range 4.1-12.5 years). There were 14 deaths (7 cancer specific) and 14 recurrences (5 local recurrences and 9 distant metastases). The median time to recurrence was 6.0 years (range 4.1-8.2 years). Grade ≥2 late toxicities were frequently observed in the bladder (19%) and small/large intestine (15%). Multivariate analysis revealed a higher rate of late toxicity in patients aged ≥51 years at diagnosis (small/large intestine: hazard ratio, HR, 2.5 [1.2-5.5]; bladder: HR 2.4 [1.3-4.5]; and bone: HR 4.3 [1.2-15.8]) than patients aged <51 years. Compared to the general population, LCCS exhibited a significantly higher rate of body image concerns, sexual dysfunction, lymphedema, and peripheral neuropathy.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">New recurrences occurred in 5% of LCCS and grade ≥2 treatment-related morbidities were present in 33%. A significant proportion of LCCS also showed decreased cervical-cancer-specific QoL. These results suggest the need for long-term surveillance and follow-up care for LCCS.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Sung Uk</LastName>
<ForeName>Lee</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang, Korea (Republic of).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Young Ae</LastName>
<ForeName>Kim</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Cancer Policy Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea (Republic of).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Young-Ho</LastName>
<ForeName>Yoon</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea (Republic of).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yeon-Joo</LastName>
<ForeName>Kim</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang, Korea (Republic of).</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea (Republic of).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Myong Cheol</LastName>
<ForeName>Lim</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea (Republic of).</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Gynecologic Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea (Republic of).</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Cancer Control and Policy, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea (Republic of).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sang-Yoon</LastName>
<ForeName>Park</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea (Republic of).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sang-Soo</LastName>
<ForeName>Seo</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea (Republic of).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ji Eun</LastName>
<ForeName>Park</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang, Korea (Republic of).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Joo-Young</LastName>
<ForeName>Kim</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang, Korea (Republic of). jooyoungcasa@ncc.re.kr.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea (Republic of). jooyoungcasa@ncc.re.kr.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Research Institute and Hospital, National Cancer Center, 323 Ilsan-ro, 410-769, Goyang, Gyeonggi, Korea (Republic of). jooyoungcasa@ncc.re.kr.</Affiliation>
</AffiliationInfo>
</Author>
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<Language>eng</Language>
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</PublicationTypeList>
<VernacularTitle>Allgemeiner Gesundheitsstatus Langzeitüberlebender von Gebärmutterhalskrebs nach Strahlentherapie.</VernacularTitle>
<ArticleDate DateType="Electronic"><Year>2017</Year>
<Month>05</Month>
<Day>10</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Germany</Country>
<MedlineTA>Strahlenther Onkol</MedlineTA>
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<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
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<MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName>
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<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
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<MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006304" MajorTopicYN="Y">Health Status</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007044" MajorTopicYN="N">Hysterectomy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007422" MajorTopicYN="N">Intestines</DescriptorName>
<QualifierName UI="Q000528" MajorTopicYN="N">radiation effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009367" MajorTopicYN="N">Neoplasm Staging</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011788" MajorTopicYN="N">Quality of Life</DescriptorName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011832" MajorTopicYN="N">Radiation Injuries</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011879" MajorTopicYN="N">Radiotherapy Dosage</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000069475" MajorTopicYN="Y">Re-Irradiation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016019" MajorTopicYN="N">Survival Analysis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017741" MajorTopicYN="Y">Survivors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001743" MajorTopicYN="N">Urinary Bladder</DescriptorName>
<QualifierName UI="Q000528" MajorTopicYN="N">radiation effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002583" MajorTopicYN="N">Uterine Cervical Neoplasms</DescriptorName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Gynecology</Keyword>
<Keyword MajorTopicYN="N">Quality of life</Keyword>
<Keyword MajorTopicYN="N">Side effects</Keyword>
<Keyword MajorTopicYN="N">Survival</Keyword>
<Keyword MajorTopicYN="N">Toxicity</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year>
<Month>11</Month>
<Day>17</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2017</Year>
<Month>04</Month>
<Day>17</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2017</Year>
<Month>5</Month>
<Day>12</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2017</Year>
<Month>8</Month>
<Day>18</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2017</Year>
<Month>5</Month>
<Day>12</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">28492995</ArticleId>
<ArticleId IdType="doi">10.1007/s00066-017-1143-8</ArticleId>
<ArticleId IdType="pii">10.1007/s00066-017-1143-8</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Corée du Sud</li>
</country>
</list>
<tree><noCountry><name sortKey="Ji Eun, Park" sort="Ji Eun, Park" uniqKey="Ji Eun P" first="Park" last="Ji Eun">Park Ji Eun</name>
<name sortKey="Myong Cheol, Lim" sort="Myong Cheol, Lim" uniqKey="Myong Cheol L" first="Lim" last="Myong Cheol">Lim Myong Cheol</name>
<name sortKey="Sang Soo, Seo" sort="Sang Soo, Seo" uniqKey="Sang Soo S" first="Seo" last="Sang-Soo">Seo Sang-Soo</name>
<name sortKey="Sang Yoon, Park" sort="Sang Yoon, Park" uniqKey="Sang Yoon P" first="Park" last="Sang-Yoon">Park Sang-Yoon</name>
<name sortKey="Sung Uk, Lee" sort="Sung Uk, Lee" uniqKey="Sung Uk L" first="Lee" last="Sung Uk">Lee Sung Uk</name>
<name sortKey="Yeon Joo, Kim" sort="Yeon Joo, Kim" uniqKey="Yeon Joo K" first="Kim" last="Yeon-Joo">Kim Yeon-Joo</name>
<name sortKey="Young Ae, Kim" sort="Young Ae, Kim" uniqKey="Young Ae K" first="Kim" last="Young Ae">Kim Young Ae</name>
<name sortKey="Young Ho, Yoon" sort="Young Ho, Yoon" uniqKey="Young Ho Y" first="Yoon" last="Young-Ho">Yoon Young-Ho</name>
</noCountry>
<country name="Corée du Sud"><noRegion><name sortKey="Joo Young, Kim" sort="Joo Young, Kim" uniqKey="Joo Young K" first="Kim" last="Joo-Young">Kim Joo-Young</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
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