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Preoperative Sentinel Node Mapping in Sentinel Node Biopsy in Early Breast Cancers - Is It Cost-Effective?

Identifieur interne : 008825 ( Ncbi/Merge ); précédent : 008824; suivant : 008826

Preoperative Sentinel Node Mapping in Sentinel Node Biopsy in Early Breast Cancers - Is It Cost-Effective?

Auteurs : Michael Co [Hong Kong] ; Ava Kwong [Hong Kong]

Source :

RBID : pubmed:27650388

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English descriptors

Abstract

Sentinel lymph node (SLN) biopsy is currently the gold standard of treatment in early breast cancers. Identification of SLNs by preoperative scintigraphy has been carried out to improve the detection of SLNs intraoperatively, but the evidence of its cost-effectiveness is lacking. Here, we analyze the cost-effectiveness of the utilization of scintigraphy in detection of SLNs.

DOI: 10.1016/j.clbc.2016.08.006
PubMed: 27650388

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pubmed:27650388

Le document en format XML

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<title xml:lang="en">Preoperative Sentinel Node Mapping in Sentinel Node Biopsy in Early Breast Cancers - Is It Cost-Effective?</title>
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<name sortKey="Co, Michael" sort="Co, Michael" uniqKey="Co M" first="Michael" last="Co">Michael Co</name>
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<nlm:affiliation>Division of Breast Surgery, Department of Surgery, Queen Mary Hospital, Hong Kong; Department of Surgery, The University of Hong Kong, Hong Kong.</nlm:affiliation>
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<term>Sentinel Lymph Node (diagnostic imaging)</term>
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<term>Treatment Outcome</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Aisselle</term>
<term>Analyse coût-bénéfice</term>
<term>Biopsie de noeud lymphatique sentinelle ()</term>
<term>Biopsie de noeud lymphatique sentinelle (économie)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Jeune adulte</term>
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<term>Noeud lymphatique sentinelle</term>
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<term>Breast Neoplasms</term>
<term>Sentinel Lymph Node</term>
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<term>Preoperative Care</term>
<term>Radionuclide Imaging</term>
<term>Sentinel Lymph Node Biopsy</term>
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<term>Neoplasm Recurrence, Local</term>
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<term>Noeud lymphatique sentinelle</term>
<term>Tumeurs du sein</term>
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<term>Preoperative Care</term>
<term>Sentinel Lymph Node Biopsy</term>
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<term>Breast Neoplasms</term>
<term>Sentinel Lymph Node</term>
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<term>Breast Neoplasms</term>
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<term>Biopsie de noeud lymphatique sentinelle</term>
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<term>Récidive tumorale locale</term>
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<term>Adult</term>
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<term>Aged, 80 and over</term>
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<term>Adulte d'âge moyen</term>
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<front>
<div type="abstract" xml:lang="en">Sentinel lymph node (SLN) biopsy is currently the gold standard of treatment in early breast cancers. Identification of SLNs by preoperative scintigraphy has been carried out to improve the detection of SLNs intraoperatively, but the evidence of its cost-effectiveness is lacking. Here, we analyze the cost-effectiveness of the utilization of scintigraphy in detection of SLNs.</div>
</front>
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<Year>2016</Year>
<Month>09</Month>
<Day>21</Day>
</DateCreated>
<DateCompleted>
<Year>2017</Year>
<Month>06</Month>
<Day>06</Day>
</DateCompleted>
<DateRevised>
<Year>2017</Year>
<Month>06</Month>
<Day>06</Day>
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<ISSN IssnType="Electronic">1938-0666</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>17</Volume>
<Issue>2</Issue>
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<Year>2017</Year>
<Month>Apr</Month>
</PubDate>
</JournalIssue>
<Title>Clinical breast cancer</Title>
<ISOAbbreviation>Clin. Breast Cancer</ISOAbbreviation>
</Journal>
<ArticleTitle>Preoperative Sentinel Node Mapping in Sentinel Node Biopsy in Early Breast Cancers - Is It Cost-Effective?</ArticleTitle>
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<Abstract>
<AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Sentinel lymph node (SLN) biopsy is currently the gold standard of treatment in early breast cancers. Identification of SLNs by preoperative scintigraphy has been carried out to improve the detection of SLNs intraoperatively, but the evidence of its cost-effectiveness is lacking. Here, we analyze the cost-effectiveness of the utilization of scintigraphy in detection of SLNs.</AbstractText>
<AbstractText Label="PATIENTS AND METHODS" NlmCategory="METHODS">Clinical and operative details were retrieved from a prospectively maintained database. The resources and cost data from each patient who had undergone SLN biopsy with preoperative scintigraphy were retrieved.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">From January 2008 to December 2012, 400 patients underwent SLN biopsy for breast cancer. A total of 329 had preoperative SLN mapping with scintigraphy, Baseline patient demographic data for both arms were comparable. The relapse and recurrence rate of both arms were not statistically different. The detection rate of SLNs of both arms was the same (100%), and there were no grade 2 or above lymphedema in both groups of patients. However, the cost of each patient undergoing SLN mapping was USD $345.8.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Preoperative SLN mapping does not improve the SLN detection rate. In addition, it does not affect the surgical outcomes in terms of complication, local relapse, and recurrence. The use of preoperative SLN mapping is no longer cost-effective.</AbstractText>
<CopyrightInformation>Copyright © 2016 Elsevier Inc. All rights reserved.</CopyrightInformation>
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<LastName>Co</LastName>
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<Keyword MajorTopicYN="N">Breast cancer</Keyword>
<Keyword MajorTopicYN="N">Cost effective</Keyword>
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