Lipedema: diagnostic and management challenges
Identifieur interne : 008741 ( Ncbi/Merge ); précédent : 008740; suivant : 008742Lipedema: diagnostic and management challenges
Auteurs : Anne Warren Peled [États-Unis] ; Elisabeth A. Kappos [Suisse]Source :
- International Journal of Women's Health [ 1179-1411 ] ; 2016.
Abstract
Lipedema is an uncommon disorder characterized by localized adiposity of the lower extremities, often occurring in females with a family history of the condition. The adiposity extends from hips to ankles and is typically unresponsive to weight loss. In addition to the aesthetic deformity, women also describe pain in the lower extremities, particularly with pressure, as well as easy bruising. Although the condition is well described, it is relatively rare and often misdiagnosed. The purpose of this review is to describe the initial evaluation and diagnosis of lipedema and discuss treatment options.
Url:
DOI: 10.2147/IJWH.S106227
PubMed: 27570465
PubMed Central: 4986968
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lipedema: diagnostic and management challenges</title><author><name sortKey="Warren Peled, Anne" sort="Warren Peled, Anne" uniqKey="Warren Peled A" first="Anne" last="Warren Peled">Anne Warren Peled</name><affiliation wicri:level="1"><nlm:aff id="af1-ijwh-8-389">Private Plastic and Reconstructive Surgery Practice, San Francisco, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Private Plastic and Reconstructive Surgery Practice, San Francisco, CA</wicri:regionArea><wicri:noRegion>CA</wicri:noRegion></affiliation></author><author><name sortKey="Kappos, Elisabeth A" sort="Kappos, Elisabeth A" uniqKey="Kappos E" first="Elisabeth A" last="Kappos">Elisabeth A. Kappos</name><affiliation wicri:level="1"><nlm:aff id="af2-ijwh-8-389">Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital, Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27570465</idno><idno type="pmc">4986968</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986968</idno><idno type="RBID">PMC:4986968</idno><idno type="doi">10.2147/IJWH.S106227</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">004A86</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">004A86</idno><idno type="wicri:Area/Pmc/Curation">004A85</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">004A85</idno><idno type="wicri:Area/Pmc/Checkpoint">000845</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000845</idno><idno type="wicri:Area/Ncbi/Merge">008741</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Lipedema: diagnostic and management challenges</title><author><name sortKey="Warren Peled, Anne" sort="Warren Peled, Anne" uniqKey="Warren Peled A" first="Anne" last="Warren Peled">Anne Warren Peled</name><affiliation wicri:level="1"><nlm:aff id="af1-ijwh-8-389">Private Plastic and Reconstructive Surgery Practice, San Francisco, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Private Plastic and Reconstructive Surgery Practice, San Francisco, CA</wicri:regionArea><wicri:noRegion>CA</wicri:noRegion></affiliation></author><author><name sortKey="Kappos, Elisabeth A" sort="Kappos, Elisabeth A" uniqKey="Kappos E" first="Elisabeth A" last="Kappos">Elisabeth A. Kappos</name><affiliation wicri:level="1"><nlm:aff id="af2-ijwh-8-389">Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital, Basel, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author></analytic><series><title level="j">International Journal of Women's Health</title><idno type="eISSN">1179-1411</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Lipedema is an uncommon disorder characterized by localized adiposity of the lower extremities, often occurring in females with a family history of the condition. The adiposity extends from hips to ankles and is typically unresponsive to weight loss. In addition to the aesthetic deformity, women also describe pain in the lower extremities, particularly with pressure, as well as easy bruising. Although the condition is well described, it is relatively rare and often misdiagnosed. The purpose of this review is to describe the initial evaluation and diagnosis of lipedema and discuss treatment options.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Wold, Le" uniqKey="Wold L">LE Wold</name></author><author><name sortKey="Hines, Ea" uniqKey="Hines E">EA Hines</name></author><author><name sortKey="Allen, Ev" uniqKey="Allen E">EV Allen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garfein, Es" uniqKey="Garfein E">ES Garfein</name></author><author><name sortKey="Borud, Lj" uniqKey="Borud L">LJ Borud</name></author><author><name sortKey="Warren, Ag" uniqKey="Warren A">AG Warren</name></author><author><name sortKey="Slavin, Sa" uniqKey="Slavin S">SA Slavin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Allen, Ev" uniqKey="Allen E">EV Allen</name></author><author><name sortKey="Hines, Ea" uniqKey="Hines E">EA 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Int J Womens Health</journal-id><journal-id journal-id-type="iso-abbrev">Int J Womens Health</journal-id><journal-id journal-id-type="publisher-id">International Journal of Women’s Health</journal-id><journal-title-group><journal-title>International Journal of Women's Health</journal-title></journal-title-group><issn pub-type="epub">1179-1411</issn><publisher><publisher-name>Dove Medical Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27570465</article-id><article-id pub-id-type="pmc">4986968</article-id><article-id pub-id-type="doi">10.2147/IJWH.S106227</article-id><article-id pub-id-type="publisher-id">ijwh-8-389</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Lipedema: diagnostic and management challenges</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Warren Peled</surname><given-names>Anne</given-names></name><xref ref-type="aff" rid="af1-ijwh-8-389">1</xref><xref ref-type="corresp" rid="c1-ijwh-8-389"></xref></contrib><contrib contrib-type="author"><name><surname>Kappos</surname><given-names>Elisabeth A</given-names></name><xref ref-type="aff" rid="af2-ijwh-8-389">2</xref></contrib></contrib-group><aff id="af1-ijwh-8-389"><label>1</label>Private Plastic and Reconstructive Surgery Practice, San Francisco, CA, USA</aff><aff id="af2-ijwh-8-389"><label>2</label>Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital, Basel, Switzerland</aff><author-notes><corresp id="c1-ijwh-8-389">Correspondence: Anne Warren Peled, Private Plastic and Reconstructive Surgery Practice, 2100 Webster Street, Suite 424, San Francisco, CA 94115, USA, Tel +1 415 923 3008, Fax +1 415 923 3846, Email <email>anne.peled@ucsf.edu</email></corresp></author-notes><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>11</day><month>8</month><year>2016</year></pub-date><volume>8</volume><fpage>389</fpage><lpage>395</lpage><permissions><copyright-statement>© 2016 Warren Peled and Kappos. This work is published and licensed by Dove Medical Press Limited</copyright-statement><copyright-year>2016</copyright-year><license><license-p>The full terms of this license are available at <ext-link ext-link-type="uri" xlink:href="https://www.dovepress.com/terms.php">https://www.dovepress.com/terms.php</ext-link> and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">http://creativecommons.org/licenses/by-nc/3.0/</ext-link>). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.</license-p></license></permissions><abstract><p>Lipedema is an uncommon disorder characterized by localized adiposity of the lower extremities, often occurring in females with a family history of the condition. The adiposity extends from hips to ankles and is typically unresponsive to weight loss. In addition to the aesthetic deformity, women also describe pain in the lower extremities, particularly with pressure, as well as easy bruising. Although the condition is well described, it is relatively rare and often misdiagnosed. The purpose of this review is to describe the initial evaluation and diagnosis of lipedema and discuss treatment options.</p></abstract><kwd-group><title>Keywords</title><kwd>lipedema</kwd><kwd>leg swelling</kwd><kwd>lipodystrophy</kwd><kwd>localized adiposity</kwd><kwd>lower extremity liposuction</kwd></kwd-group></article-meta></front><floats-group><fig id="f1-ijwh-8-389" position="float"><label>Figure 1</label><caption><p>A 43-year-old woman with long-standing lipedema.</p></caption><graphic xlink:href="ijwh-8-389Fig1"></graphic></fig><fig id="f2-ijwh-8-389" position="float"><label>Figure 2</label><caption><p>Characteristic “step-off” seen at the ankles in patients with lipedema.</p></caption><graphic xlink:href="ijwh-8-389Fig2"></graphic></fig><fig id="f3-ijwh-8-389" position="float"><label>Figure 3</label><caption><p>Algorithm for workup in patients presenting with lower extremity enlargement.</p><p><bold>Abbreviation:</bold> CT/MRI, computed tomography/magnetic resonance imaging.</p></caption><graphic xlink:href="ijwh-8-389Fig3"></graphic></fig><fig id="f4-ijwh-8-389" position="float"><label>Figure 4</label><caption><p>CT scan of a patient with lipedema demonstrating homogenous, circumferential fatty hypertrophy.</p><p><bold>Abbreviation:</bold> CT, computed tomography.</p></caption><graphic xlink:href="ijwh-8-389Fig4"></graphic></fig><fig id="f5-ijwh-8-389" position="float"><label>Figure 5</label><caption><p>Algorithm for management of diagnosed lipedema.</p></caption><graphic xlink:href="ijwh-8-389Fig5"></graphic></fig><table-wrap id="t1-ijwh-8-389" position="float"><label>Table 1</label><caption><p>Differential diagnosis for lipedema</p></caption><table frame="hsides" rules="groups"><tbody><tr><td valign="top" align="left" rowspan="1" colspan="1"><bold>Causes of lower extremity swelling</bold></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Lymphedema</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Venous disease (chronic venous insufficiency, deep vein thrombosis)</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Systemic disease (congestive heart failure, renal disease, hypoalbuminemia)</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Cellulitis</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Cyclical and idiopathic edema</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Myxedema</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"><bold>Causes of lower extremity fatty excess</bold></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Generalized obesity</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Localized adiposity</td></tr></tbody></table></table-wrap></floats-group></pmc><affiliations><list><country><li>Suisse</li><li>États-Unis</li></country></list><tree><country name="États-Unis"><noRegion><name sortKey="Warren Peled, Anne" sort="Warren Peled, Anne" uniqKey="Warren Peled A" first="Anne" last="Warren Peled">Anne Warren Peled</name></noRegion></country><country name="Suisse"><noRegion><name sortKey="Kappos, Elisabeth A" sort="Kappos, Elisabeth A" uniqKey="Kappos E" first="Elisabeth A" last="Kappos">Elisabeth A. 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|étape= Merge
|type= RBID
|clé= PMC:4986968
|texte= Lipedema: diagnostic and management challenges
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:27570465" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |