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Successful treatment of a chronic abdominal wall seroma with the polysaccharide 4DryField® PH − A case report

Identifieur interne : 008711 ( Ncbi/Merge ); précédent : 008710; suivant : 008712

Successful treatment of a chronic abdominal wall seroma with the polysaccharide 4DryField® PH − A case report

Auteurs : Andreas Kuthe

Source :

RBID : PMC:4992008

Abstract

Highlights

Chronic subcutaneous seroma therapy with the polysaccharide 4DryField® PH .

4DryField® evenly distributed in the former seroma cavity prevents its recurrence.

Long-term treatment success confirmed 1,5 years later.

First clinical evidence that 4DryField® can prevent seroma recurrence.


Url:
DOI: 10.1016/j.ijscr.2016.08.012
PubMed: 27541060
PubMed Central: 4992008

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PMC:4992008

Le document en format XML

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<title xml:lang="en">Successful treatment of a chronic abdominal wall seroma with the polysaccharide 4DryField
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<title xml:lang="en" level="a" type="main">Successful treatment of a chronic abdominal wall seroma with the polysaccharide 4DryField
<sup>®</sup>
PH − A case report</title>
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<label></label>
<p>Chronic subcutaneous seroma therapy with the polysaccharide 4DryField
<sup>®</sup>
PH .</p>
</list-item>
<list-item id="lsti0010">
<label></label>
<p>4DryField
<sup>®</sup>
evenly distributed in the former seroma cavity prevents its recurrence.</p>
</list-item>
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<label></label>
<p>Long-term treatment success confirmed 1,5 years later.</p>
</list-item>
<list-item id="lsti0020">
<label></label>
<p>First clinical evidence that 4DryField
<sup>®</sup>
can prevent seroma recurrence.</p>
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<pmc article-type="case-report">
<pmc-dir>properties open_access</pmc-dir>
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<journal-meta>
<journal-id journal-id-type="nlm-ta">Int J Surg Case Rep</journal-id>
<journal-id journal-id-type="iso-abbrev">Int J Surg Case Rep</journal-id>
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<journal-title>International Journal of Surgery Case Reports</journal-title>
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<publisher-name>Elsevier</publisher-name>
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<article-id pub-id-type="pmid">27541060</article-id>
<article-id pub-id-type="pmc">4992008</article-id>
<article-id pub-id-type="publisher-id">S2210-2612(16)30307-8</article-id>
<article-id pub-id-type="doi">10.1016/j.ijscr.2016.08.012</article-id>
<article-categories>
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<subject>Case Report</subject>
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<title-group>
<article-title>Successful treatment of a chronic abdominal wall seroma with the polysaccharide 4DryField
<sup>®</sup>
PH − A case report</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Kuthe</surname>
<given-names>Andreas</given-names>
</name>
<degrees>Dr., MD</degrees>
<email>AKuthe@clementinenhaus.de</email>
</contrib>
</contrib-group>
<aff id="aff0005">Department of General Surgery and Traumatology, DRK-Krankenhaus, Clementinenhaus, Lützerodestr. 1, 30161 Hannover, Germany</aff>
<pub-date pub-type="pmc-release">
<day>11</day>
<month>8</month>
<year>2016</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="collection">
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>11</day>
<month>8</month>
<year>2016</year>
</pub-date>
<volume>27</volume>
<fpage>48</fpage>
<lpage>50</lpage>
<history>
<date date-type="received">
<day>13</day>
<month>6</month>
<year>2016</year>
</date>
<date date-type="accepted">
<day>7</day>
<month>8</month>
<year>2016</year>
</date>
</history>
<permissions>
<copyright-statement>© 2016 The Author</copyright-statement>
<copyright-year>2016</copyright-year>
<license license-type="CC BY-NC-ND" xlink:href="http://creativecommons.org/licenses/by-nc-nd/4.0/">
<license-p>This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).</license-p>
</license>
</permissions>
<abstract abstract-type="author-highlights" id="abs0005">
<title>Highlights</title>
<p>
<list list-type="simple">
<list-item id="lsti0005">
<label></label>
<p>Chronic subcutaneous seroma therapy with the polysaccharide 4DryField
<sup>®</sup>
PH .</p>
</list-item>
<list-item id="lsti0010">
<label></label>
<p>4DryField
<sup>®</sup>
evenly distributed in the former seroma cavity prevents its recurrence.</p>
</list-item>
<list-item id="lsti0015">
<label></label>
<p>Long-term treatment success confirmed 1,5 years later.</p>
</list-item>
<list-item id="lsti0020">
<label></label>
<p>First clinical evidence that 4DryField
<sup>®</sup>
can prevent seroma recurrence.</p>
</list-item>
</list>
</p>
</abstract>
<abstract id="abs0010">
<sec>
<title>Introduction</title>
<p>Seroma formation is one of the most prevalent complications after liposuction, abdominoplasty, mastectomy or hernia repair. They can disappear without treatment, but also may persist and require complex therapy. This report describes how 4DryField
<sup>®</sup>
PH polysaccharide powder successfully was applied for chronic seroma therapy.</p>
</sec>
<sec>
<title>Presentation of the case</title>
<p>An 80 year old male patient presented with a persistent seroma (1000 cm
<sup>3</sup>
volume) resulting from liposuction about 15 years ago. In a first approach he was treated using en bloc excision without opening the capsule. Three month later the patient presented with a recurrent seroma of the same size. This time 1100 cm
<sup>3</sup>
bloody discolored fluid was aspirated. The skin was lifted using a redon tubing drawn through the whole length of the wound cavity. This allowed even distribution of 4DryField
<sup>®</sup>
PH powder (10 g) within the former seroma cavity. Computed Tomography (CT) imaging after 4.5 month and sonographic examination after an additional year confirmed treatment success.</p>
</sec>
<sec>
<title>Discussion</title>
<p>Besides conventional methods for hemos-/lymphostasis several adjunct measures like fibrin sealants, medication with corticoids and diurectics have been proposed for seroma prevention/therapy, unfortunately, with conflicting evidence. In an experimental study seroma prevention with a polysaccharide was demonstrated; however, clinical proof is missing. This case provides first clinical evidence that 4DryField
<sup>®</sup>
PH polysaccharide powder evenly distributed in the former seroma cavity can prevent its recurrence.</p>
</sec>
<sec>
<title>Conclusion</title>
<p>4DryField
<sup>®</sup>
PH powder treatment of seroma is a promising new approach for prevention and treatment of chronic seroma.</p>
</sec>
</abstract>
<kwd-group id="kwd0005">
<title>Keywords</title>
<kwd>Starch based medical device</kwd>
<kwd>Chronic</kwd>
<kwd>Subcutaneous</kwd>
<kwd>Seroma</kwd>
<kwd>Liposuction</kwd>
</kwd-group>
</article-meta>
</front>
<floats-group>
<fig id="fig0005">
<label>Fig. 1</label>
<caption>
<p>Right abdominal wall chronic hematoma/seroma. a) MRI before treatment. b) CT 4.5 month after treatment with 10 g of 4DryField
<sup>®</sup>
PH powder.</p>
</caption>
<alt-text id="at0155">Fig. 1</alt-text>
<graphic xlink:href="gr1"></graphic>
</fig>
<fig id="fig0010">
<label>Fig. 2</label>
<caption>
<p>Application strategy. a) 4DryField
<sup>®</sup>
PH applicator extended with shortened 12F anastetic tube to access seroma cavity center. b) A redon drain was inserted from one pole of original incision to the other to lift the skin. Tent-shaped lifting of skin allowed for even distribution of 4DryField
<sup>®</sup>
PH in the wound cavity.</p>
</caption>
<alt-text id="at0160">Fig. 2</alt-text>
<graphic xlink:href="gr2"></graphic>
</fig>
</floats-group>
</pmc>
<affiliations>
<list></list>
<tree>
<noCountry>
<name sortKey="Kuthe, Andreas" sort="Kuthe, Andreas" uniqKey="Kuthe A" first="Andreas" last="Kuthe">Andreas Kuthe</name>
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