LymphedemaV1, Ncbi, Merge, bibRecord, 008325

Radiation Associated Angiosarcoma: Case Series from a Community Cancer Center and Review of the Literature.

Identifieur interne : 008325 ( Ncbi/Merge ); précédent : 008324; suivant : 008326

Radiation Associated Angiosarcoma: Case Series from a Community Cancer Center and Review of the Literature.

Auteurs : Ian N. Wilhelm ; Emily J. Penman

Source :

Delaware medical journal [ 0011-7781 ] ; 2016.

RBID : pubmed:27215044

Descripteurs français

KwdFr :
- Adulte d'âge moyen, Amplification de gène, Femelle, Humains, Hémangiosarcome (), Hémangiosarcome (diagnostic), Maladies rares, Protéines proto-oncogènes c-myc (génétique), Sujet âgé, Sujet âgé de 80 ans ou plus, Tumeurs du sein (), Tumeurs du sein (diagnostic), Tumeurs radio-induites (), Tumeurs radio-induites (diagnostic), Études rétrospectives.
MESH :
- diagnostic : Hémangiosarcome, Tumeurs du sein, Tumeurs radio-induites.
- génétique : Protéines proto-oncogènes c-myc.
- Adulte d'âge moyen, Amplification de gène, Femelle, Humains, Hémangiosarcome, Maladies rares, Sujet âgé, Sujet âgé de 80 ans ou plus, Tumeurs du sein, Tumeurs radio-induites, Études rétrospectives.

English descriptors

KwdEn :
- Aged, Aged, 80 and over, Breast Neoplasms (diagnosis), Breast Neoplasms (therapy), Female, Gene Amplification, Hemangiosarcoma (diagnosis), Hemangiosarcoma (therapy), Humans, Middle Aged, Neoplasms, Radiation-Induced (diagnosis), Neoplasms, Radiation-Induced (therapy), Proto-Oncogene Proteins c-myc (genetics), Rare Diseases, Retrospective Studies.
MESH :
- chemical , genetics : Proto-Oncogene Proteins c-myc.
- diagnosis : Breast Neoplasms, Hemangiosarcoma, Neoplasms, Radiation-Induced.
- therapy : Breast Neoplasms, Hemangiosarcoma, Neoplasms, Radiation-Induced.
- Aged, Aged, 80 and over, Female, Gene Amplification, Humans, Middle Aged, Rare Diseases, Retrospective Studies.

Abstract

Radiation associated angiosarcoma (RAAS) of the breast is a rare, but lethal complication of breast conserving surgery (BCS). Early recognition and knowledge of treatment modalities is imperative for successful treatment. We present the experience of a large community cancer center, with review of the literature.

PubMed: 27215044

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pubmed:27215044

Le document en format XML

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<author><name sortKey="Wilhelm, Ian N" sort="Wilhelm, Ian N" uniqKey="Wilhelm I" first="Ian N" last="Wilhelm">Ian N. Wilhelm</name>
</author>
<author><name sortKey="Penman, Emily J" sort="Penman, Emily J" uniqKey="Penman E" first="Emily J" last="Penman">Emily J. Penman</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Breast Neoplasms (diagnosis)</term>
<term>Breast Neoplasms (therapy)</term>
<term>Female</term>
<term>Gene Amplification</term>
<term>Hemangiosarcoma (diagnosis)</term>
<term>Hemangiosarcoma (therapy)</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Neoplasms, Radiation-Induced (diagnosis)</term>
<term>Neoplasms, Radiation-Induced (therapy)</term>
<term>Proto-Oncogene Proteins c-myc (genetics)</term>
<term>Rare Diseases</term>
<term>Retrospective Studies</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Amplification de gène</term>
<term>Femelle</term>
<term>Humains</term>
<term>Hémangiosarcome ()</term>
<term>Hémangiosarcome (diagnostic)</term>
<term>Maladies rares</term>
<term>Protéines proto-oncogènes c-myc (génétique)</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tumeurs du sein ()</term>
<term>Tumeurs du sein (diagnostic)</term>
<term>Tumeurs radio-induites ()</term>
<term>Tumeurs radio-induites (diagnostic)</term>
<term>Études rétrospectives</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Proto-Oncogene Proteins c-myc</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Breast Neoplasms</term>
<term>Hemangiosarcoma</term>
<term>Neoplasms, Radiation-Induced</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Hémangiosarcome</term>
<term>Tumeurs du sein</term>
<term>Tumeurs radio-induites</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Protéines proto-oncogènes c-myc</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Breast Neoplasms</term>
<term>Hemangiosarcoma</term>
<term>Neoplasms, Radiation-Induced</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Gene Amplification</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Rare Diseases</term>
<term>Retrospective Studies</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Amplification de gène</term>
<term>Femelle</term>
<term>Humains</term>
<term>Hémangiosarcome</term>
<term>Maladies rares</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tumeurs du sein</term>
<term>Tumeurs radio-induites</term>
<term>Études rétrospectives</term>
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<front><div type="abstract" xml:lang="en">Radiation associated angiosarcoma (RAAS) of the breast is a rare, but lethal complication of breast conserving surgery (BCS). Early recognition and knowledge of treatment modalities is imperative for successful treatment. We present the experience of a large community cancer center, with review of the literature.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27215044</PMID>
<DateCreated><Year>2016</Year>
<Month>05</Month>
<Day>24</Day>
</DateCreated>
<DateCompleted><Year>2016</Year>
<Month>06</Month>
<Day>16</Day>
</DateCompleted>
<DateRevised><Year>2016</Year>
<Month>05</Month>
<Day>24</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0011-7781</ISSN>
<JournalIssue CitedMedium="Print"><Volume>88</Volume>
<Issue>3</Issue>
<PubDate><Year>2016</Year>
<Month>Mar</Month>
</PubDate>
</JournalIssue>
<Title>Delaware medical journal</Title>
<ISOAbbreviation>Del Med J</ISOAbbreviation>
</Journal>
<ArticleTitle>Radiation Associated Angiosarcoma: Case Series from a Community Cancer Center and Review of the Literature.</ArticleTitle>
<Pagination><MedlinePgn>78-82</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Radiation associated angiosarcoma (RAAS) of the breast is a rare, but lethal complication of breast conserving surgery (BCS). Early recognition and knowledge of treatment modalities is imperative for successful treatment. We present the experience of a large community cancer center, with review of the literature.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">The Christiana Care Department of Pathology and the Helen F. Graham Cancer Center and Research Institute databases were queried from 2001-2011 and 2011-2015 respectively for soft tissue neoplasms of the breast. A total of 2,153 patients with diagnosis of malignant neoplasm of the breast not otherwise specified (NOS) were identified. There were seven cases of RAAS identified.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Seven patients with RAAS were identified. Average age at presentation was 70 years with a range of 58-87. Time from radiation therapy to diagnosis was 8.5 years with a range of 4.0 years to 14.9 years. Five of seven patients presented with skin lesions, all with varying clinical signs. Clinical lymphedema was not identified in any of these patients.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Radiation associated angiosarcoma of the breast is an aggressive tumor with poor prognosis. Larger studies are needed to evaluate adjuvant treatments; however the small number of cases makes this prohibitive. Genetic testing and potentially targeted therapies are emerging as options for treatment and prevention of this complicated disease process.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wilhelm</LastName>
<ForeName>Ian N</ForeName>
<Initials>IN</Initials>
</Author>
<Author ValidYN="Y"><LastName>Penman</LastName>
<ForeName>Emily J</ForeName>
<Initials>EJ</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016454">Review</PublicationType>
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<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Del Med J</MedlineTA>
<NlmUniqueID>0370077</NlmUniqueID>
<ISSNLinking>0011-7781</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C489427">MYC protein, human</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D016271">Proto-Oncogene Proteins c-myc</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001943" MajorTopicYN="N">Breast Neoplasms</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005784" MajorTopicYN="N">Gene Amplification</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006394" MajorTopicYN="N">Hemangiosarcoma</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009381" MajorTopicYN="N">Neoplasms, Radiation-Induced</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016271" MajorTopicYN="N">Proto-Oncogene Proteins c-myc</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D035583" MajorTopicYN="N">Rare Diseases</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
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<Month>5</Month>
<Day>25</Day>
<Hour>6</Hour>
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<PubMedPubDate PubStatus="medline"><Year>2016</Year>
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<tree><noCountry><name sortKey="Penman, Emily J" sort="Penman, Emily J" uniqKey="Penman E" first="Emily J" last="Penman">Emily J. Penman</name>
<name sortKey="Wilhelm, Ian N" sort="Wilhelm, Ian N" uniqKey="Wilhelm I" first="Ian N" last="Wilhelm">Ian N. Wilhelm</name>
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</record>

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Radiation Associated Angiosarcoma: Case Series from a Community Cancer Center and Review of the Literature.

Radiation Associated Angiosarcoma: Case Series from a Community Cancer Center and Review of the Literature.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki