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Comparison of 1470 nm Laser and Radial 2ring Fiber with 980 nm Laser and Bare-Tip Fiber in Endovenous Laser Ablation of Saphenous Varicose Veins: A Multicenter, Prospective, Randomized, Non-Blind Study

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Comparison of 1470 nm Laser and Radial 2ring Fiber with 980 nm Laser and Bare-Tip Fiber in Endovenous Laser Ablation of Saphenous Varicose Veins: A Multicenter, Prospective, Randomized, Non-Blind Study

Auteurs : Masayuki Hirokawa [Japon] ; Tomohiro Ogawa [Japon] ; Hiromitsu Sugawara [Japon] ; Shintaro Shokoku [Japon] ; Shoji Sato [Japon]

Source :

Annals of Vascular Diseases [ 1881-641X ] ; 2015.

RBID : PMC:4691501

Abstract

Objective: The aim of this study is to compare the clinical efficacy and safety of two laser wavelengths and fiber types in endovenous laser ablation (EVLA) of saphenous varicose veins of the lower limb. Design: Multi-center prospective randomized non-blind clinical trial.

Patients and Methods: From January 2007 to December 2011, 113 patients (113 limbs) with primary varicose veins were randomized into two groups. They were treated with radial 2ring fiber and 1470 nm laser in Group I (57 limbs) and bare-tip fiber and 980 nm laser in Group E (56 limbs) in order to ablate the saphenous vein. Vein occlusion rates at 12 weeks and pain in treated region were recorded as primary endpoint. Visual analogue scale (VAS) for assessment of pain, rates of bruising, complications and equipment failure were recorded as secondary endpoint of safety.

Results: Occlusion rates at 12 weeks were 100% in both groups. Rates of pain (0% vs. 25.0%) and bruising (7.0% vs. 57.1%) were significantly lower in Group I (p <0.0001). VAS of pain was significantly lower on postoperative day 1, day 5 and 2nd week in Group I.

Conclusion: Treatment of saphenous varicose veins by EVLA using a 1470 nm laser and a radial 2ring fiber resulted in comparable occlusion rates at 12 weeks and less postoperative pain and bruising than EVLA with a 980 nm laser and a bare-tip fiber. (This article is a translation of Jpn J Vasc Surg 2014; 23: 964–971.)

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691501

DOI: 10.3400/avd.oa.15-00084
PubMed: 26730252
PubMed Central: 4691501

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<author><name sortKey="Hirokawa, Masayuki" sort="Hirokawa, Masayuki" uniqKey="Hirokawa M" first="Masayuki" last="Hirokawa">Masayuki Hirokawa</name>
<affiliation wicri:level="3"><nlm:aff id="aff1">Ochanomizu Vascular and Vein Clinic, Tokyo, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Ochanomizu Vascular and Vein Clinic, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
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<author><name sortKey="Ogawa, Tomohiro" sort="Ogawa, Tomohiro" uniqKey="Ogawa T" first="Tomohiro" last="Ogawa">Tomohiro Ogawa</name>
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<wicri:regionArea>Cardiovascular Center, Fukushima Daiichi Hospital, Koriyama, Fukushima</wicri:regionArea>
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<author><name sortKey="Sugawara, Hiromitsu" sort="Sugawara, Hiromitsu" uniqKey="Sugawara H" first="Hiromitsu" last="Sugawara">Hiromitsu Sugawara</name>
<affiliation wicri:level="1"><nlm:aff id="aff3">Department of Surgery, Sendai Hospital of East Japan Railway Company, Sendai, Miyagi, Japan</nlm:aff>
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<author><name sortKey="Shokoku, Shintaro" sort="Shokoku, Shintaro" uniqKey="Shokoku S" first="Shintaro" last="Shokoku">Shintaro Shokoku</name>
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<author><name sortKey="Sato, Shoji" sort="Sato, Shoji" uniqKey="Sato S" first="Shoji" last="Sato">Shoji Sato</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Comparison of 1470 nm Laser and Radial 2ring Fiber with 980 nm Laser and Bare-Tip Fiber in Endovenous Laser Ablation of Saphenous Varicose Veins: A Multicenter, Prospective, Randomized, Non-Blind Study</title>
<author><name sortKey="Hirokawa, Masayuki" sort="Hirokawa, Masayuki" uniqKey="Hirokawa M" first="Masayuki" last="Hirokawa">Masayuki Hirokawa</name>
<affiliation wicri:level="3"><nlm:aff id="aff1">Ochanomizu Vascular and Vein Clinic, Tokyo, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Ochanomizu Vascular and Vein Clinic, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
<region type="région">Région de Kantō</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ogawa, Tomohiro" sort="Ogawa, Tomohiro" uniqKey="Ogawa T" first="Tomohiro" last="Ogawa">Tomohiro Ogawa</name>
<affiliation wicri:level="1"><nlm:aff id="aff2">Cardiovascular Center, Fukushima Daiichi Hospital, Koriyama, Fukushima, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Cardiovascular Center, Fukushima Daiichi Hospital, Koriyama, Fukushima</wicri:regionArea>
<wicri:noRegion>Fukushima</wicri:noRegion>
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<author><name sortKey="Sugawara, Hiromitsu" sort="Sugawara, Hiromitsu" uniqKey="Sugawara H" first="Hiromitsu" last="Sugawara">Hiromitsu Sugawara</name>
<affiliation wicri:level="1"><nlm:aff id="aff3">Department of Surgery, Sendai Hospital of East Japan Railway Company, Sendai, Miyagi, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
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<author><name sortKey="Shokoku, Shintaro" sort="Shokoku, Shintaro" uniqKey="Shokoku S" first="Shintaro" last="Shokoku">Shintaro Shokoku</name>
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<country xml:lang="fr">Japon</country>
<wicri:regionArea>Shokoku Shintaro Clinic, Okayama, Okayama</wicri:regionArea>
<wicri:noRegion>Okayama</wicri:noRegion>
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<author><name sortKey="Sato, Shoji" sort="Sato, Shoji" uniqKey="Sato S" first="Shoji" last="Sato">Shoji Sato</name>
<affiliation wicri:level="1"><nlm:aff id="aff5">Tsukuba Vascular Center, Moriyakeiyu Hospital, Moriya, Ibaraki, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Tsukuba Vascular Center, Moriyakeiyu Hospital, Moriya, Ibaraki</wicri:regionArea>
<wicri:noRegion>Ibaraki</wicri:noRegion>
</affiliation>
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<series><title level="j">Annals of Vascular Diseases</title>
<idno type="ISSN">1881-641X</idno>
<idno type="eISSN">1881-6428</idno>
<imprint><date when="2015">2015</date>
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<front><div type="abstract" xml:lang="en"><p><bold>Objective:</bold>
 The aim of this study is to compare the clinical efficacy and safety of two laser wavelengths and fiber types in endovenous laser ablation (EVLA) of saphenous varicose veins of the lower limb. Design: Multi-center prospective randomized non-blind clinical trial.</p>
<p><bold>Patients and Methods:</bold>
 From January 2007 to December 2011, 113 patients (113 limbs) with primary varicose veins were randomized into two groups. They were treated with radial 2ring fiber and 1470 nm laser in Group I (57 limbs) and bare-tip fiber and 980 nm laser in Group E (56 limbs) in order to ablate the saphenous vein. Vein occlusion rates at 12 weeks and pain in treated region were recorded as primary endpoint. Visual analogue scale (VAS) for assessment of pain, rates of bruising, complications and equipment failure were recorded as secondary endpoint of safety.</p>
<p><bold>Results:</bold>
 Occlusion rates at 12 weeks were 100% in both groups. Rates of pain (0% vs. 25.0%) and bruising (7.0% vs. 57.1%) were significantly lower in Group I (p <0.0001). VAS of pain was significantly lower on postoperative day 1, day 5 and 2nd week in Group I.</p>
<p><bold>Conclusion:</bold>
 Treatment of saphenous varicose veins by EVLA using a 1470 nm laser and a radial 2ring fiber resulted in comparable occlusion rates at 12 weeks and less postoperative pain and bruising than EVLA with a 980 nm laser and a bare-tip fiber. (This article is a translation of Jpn J Vasc Surg 2014; 23: 964–971.)</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
  <front><journal-meta><journal-id journal-id-type="nlm-ta">Ann Vasc Dis</journal-id>
<journal-id journal-id-type="iso-abbrev">Ann Vasc Dis</journal-id>
<journal-id journal-id-type="pmc">avd</journal-id>
<journal-title-group><journal-title>Annals of Vascular Diseases</journal-title>
</journal-title-group>
<issn pub-type="ppub">1881-641X</issn>
<issn pub-type="epub">1881-6428</issn>
<publisher><publisher-name>The Editorial Committee of Annals of Vascular Diseases</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">26730252</article-id>
<article-id pub-id-type="pmc">4691501</article-id>
<article-id pub-id-type="publisher-id">avd.oa.15-00084</article-id>
<article-id pub-id-type="doi">10.3400/avd.oa.15-00084</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Comparison of 1470 nm Laser and Radial 2ring Fiber with 980 nm Laser and Bare-Tip Fiber in Endovenous Laser Ablation of Saphenous Varicose Veins: A Multicenter, Prospective, Randomized, Non-Blind Study</article-title>
<alt-title alt-title-type="left-running-head">Hirokawa M, et al.</alt-title>
<alt-title alt-title-type="right-running-head">Comparison of 1470 and 980 nm Laser in EVLA</alt-title>
</title-group>
<contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Hirokawa</surname>
<given-names>Masayuki</given-names>
</name>
<degrees>MD, PhD</degrees>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ogawa</surname>
<given-names>Tomohiro</given-names>
</name>
<degrees>MD, PhD</degrees>
<xref ref-type="aff" rid="aff2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sugawara</surname>
<given-names>Hiromitsu</given-names>
</name>
<degrees>MD, PhD</degrees>
<xref ref-type="aff" rid="aff3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Shokoku</surname>
<given-names>Shintaro</given-names>
</name>
<degrees>MD, PhD</degrees>
<xref ref-type="aff" rid="aff4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sato</surname>
<given-names>Shoji</given-names>
</name>
<degrees>MD, PhD</degrees>
<xref ref-type="aff" rid="aff5">5</xref>
</contrib>
<aff id="aff1">Ochanomizu Vascular and Vein Clinic, Tokyo, Japan</aff>
<aff id="aff2">Cardiovascular Center, Fukushima Daiichi Hospital, Koriyama, Fukushima, Japan</aff>
<aff id="aff3">Department of Surgery, Sendai Hospital of East Japan Railway Company, Sendai, Miyagi, Japan</aff>
<aff id="aff4">Shokoku Shintaro Clinic, Okayama, Okayama, Japan</aff>
<aff id="aff5">Tsukuba Vascular Center, Moriyakeiyu Hospital, Moriya, Ibaraki, Japan</aff>
</contrib-group>
<author-notes><corresp>Corresponding author: Masayuki Hirokawa. Ochanomizu Vascular and Vein Clinic, Hillcrest Ochanomizu Bldg., 5th Floor, 2-1-4, Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan Tel: +81-3-5281-4103, Fax: +81-3-5281-4102</corresp>
<fn><p>E-mail: <email xlink:href="mailto:gea01265@nifty.com">gea01265@nifty.com</email>
</p>
</fn>
</author-notes>
<pub-date pub-type="epub"><day>9</day>
<month>9</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="ppub"><year>2015</year>
</pub-date>
<volume>8</volume>
<issue>4</issue>
<fpage>282</fpage>
<lpage>289</lpage>
<history><date date-type="received"><day>13</day>
<month>8</month>
<year>2015</year>
</date>
<date date-type="accepted"><day>13</day>
<month>8</month>
<year>2015</year>
</date>
</history>
<permissions><copyright-statement>© Annals of Vascular Diseases 2015</copyright-statement>
<copyright-year>2015</copyright-year>
</permissions>
<abstract><p><bold>Objective:</bold>
 The aim of this study is to compare the clinical efficacy and safety of two laser wavelengths and fiber types in endovenous laser ablation (EVLA) of saphenous varicose veins of the lower limb. Design: Multi-center prospective randomized non-blind clinical trial.</p>
<p><bold>Patients and Methods:</bold>
 From January 2007 to December 2011, 113 patients (113 limbs) with primary varicose veins were randomized into two groups. They were treated with radial 2ring fiber and 1470 nm laser in Group I (57 limbs) and bare-tip fiber and 980 nm laser in Group E (56 limbs) in order to ablate the saphenous vein. Vein occlusion rates at 12 weeks and pain in treated region were recorded as primary endpoint. Visual analogue scale (VAS) for assessment of pain, rates of bruising, complications and equipment failure were recorded as secondary endpoint of safety.</p>
<p><bold>Results:</bold>
 Occlusion rates at 12 weeks were 100% in both groups. Rates of pain (0% vs. 25.0%) and bruising (7.0% vs. 57.1%) were significantly lower in Group I (p <0.0001). VAS of pain was significantly lower on postoperative day 1, day 5 and 2nd week in Group I.</p>
<p><bold>Conclusion:</bold>
 Treatment of saphenous varicose veins by EVLA using a 1470 nm laser and a radial 2ring fiber resulted in comparable occlusion rates at 12 weeks and less postoperative pain and bruising than EVLA with a 980 nm laser and a bare-tip fiber. (This article is a translation of Jpn J Vasc Surg 2014; 23: 964–971.)</p>
</abstract>
<kwd-group><title>Keywords</title>
<kwd>varicose vein</kwd>
<kwd>1470 nm laser</kwd>
<kwd>radial 2ring fiber</kwd>
<kwd>endovenous laser ablation</kwd>
<kwd>VAS score</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
<affiliations><list><country><li>Japon</li>
</country>
<region><li>Région de Kantō</li>
</region>
<settlement><li>Tokyo</li>
</settlement>
</list>
<tree><country name="Japon"><region name="Région de Kantō"><name sortKey="Hirokawa, Masayuki" sort="Hirokawa, Masayuki" uniqKey="Hirokawa M" first="Masayuki" last="Hirokawa">Masayuki Hirokawa</name>
</region>
<name sortKey="Ogawa, Tomohiro" sort="Ogawa, Tomohiro" uniqKey="Ogawa T" first="Tomohiro" last="Ogawa">Tomohiro Ogawa</name>
<name sortKey="Sato, Shoji" sort="Sato, Shoji" uniqKey="Sato S" first="Shoji" last="Sato">Shoji Sato</name>
<name sortKey="Shokoku, Shintaro" sort="Shokoku, Shintaro" uniqKey="Shokoku S" first="Shintaro" last="Shokoku">Shintaro Shokoku</name>
<name sortKey="Sugawara, Hiromitsu" sort="Sugawara, Hiromitsu" uniqKey="Sugawara H" first="Hiromitsu" last="Sugawara">Hiromitsu Sugawara</name>
</country>
</tree>
</affiliations>
</record>

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Comparison of 1470 nm Laser and Radial 2ring Fiber with 980 nm Laser and Bare-Tip Fiber in Endovenous Laser Ablation of Saphenous Varicose Veins: A Multicenter, Prospective, Randomized, Non-Blind Study

Comparison of 1470 nm Laser and Radial 2ring Fiber with 980 nm Laser and Bare-Tip Fiber in Endovenous Laser Ablation of Saphenous Varicose Veins: A Multicenter, Prospective, Randomized, Non-Blind Study

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Abstract

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