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A Propensity-Matched Analysis of the Influence of Breast Reconstruction on Subsequent Development of Lymphedema.

Identifieur interne : 007677 ( Ncbi/Merge ); précédent : 007676; suivant : 007678

A Propensity-Matched Analysis of the Influence of Breast Reconstruction on Subsequent Development of Lymphedema.

Auteurs : Marten N. Basta ; John P. Fischer ; Suhail K. Kanchwala ; Jason Silvestre ; Liza C. Wu ; Joseph M. Serletti ; Julia C. Tchou ; Stephen J. Kovach ; Joshua Fosnot

Source :

RBID : pubmed:26218386

Descripteurs français

English descriptors

Abstract

Recent literature demonstrates a lower incidence of lymphedema with breast reconstruction. This study compared the incidence of lymphedema after axillary dissection in a propensity-matched cohort of patients with and without immediate breast reconstruction.

DOI: 10.1097/PRS.0000000000001417
PubMed: 26218386

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pubmed:26218386

Le document en format XML

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<front>
<div type="abstract" xml:lang="en">Recent literature demonstrates a lower incidence of lymphedema with breast reconstruction. This study compared the incidence of lymphedema after axillary dissection in a propensity-matched cohort of patients with and without immediate breast reconstruction.</div>
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<Month>10</Month>
<Day>20</Day>
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<ISSN IssnType="Electronic">1529-4242</ISSN>
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<Volume>136</Volume>
<Issue>2</Issue>
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<Year>2015</Year>
<Month>Aug</Month>
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<Title>Plastic and reconstructive surgery</Title>
<ISOAbbreviation>Plast. Reconstr. Surg.</ISOAbbreviation>
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<ArticleTitle>A Propensity-Matched Analysis of the Influence of Breast Reconstruction on Subsequent Development of Lymphedema.</ArticleTitle>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Recent literature demonstrates a lower incidence of lymphedema with breast reconstruction. This study compared the incidence of lymphedema after axillary dissection in a propensity-matched cohort of patients with and without immediate breast reconstruction.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A review of patients undergoing axillary lymphadenectomy with or without immediate breast reconstruction from January 1, 2000, to July 1, 2013, was conducted. Comorbidities, cancer treatment, operative characteristics, and pathologic findings were reviewed. The primary outcome was postoperative lymphedema. Univariate analysis identified baseline differences between the patient groups. Cohorts were propensity-matched by age, body mass index greater than 30 kg/m, adjuvant radiation therapy, cardiovascular disease, and hypertension. Subsequent multivariate regression was performed to identify independent predictors of lymphedema among matched patients.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 4647 patients underwent breast cancer resection, with 1955 having axillary lymphadenectomy (no reconstruction, n = 1200; autologous, n = 563; implant-based, n = 192). Matching yielded a cohort of 239 reconstruction and 239 no-reconstruction patients demonstrating no differences in age, body mass index, hypertension, adjuvant radiation therapy, or axillary dissection extent. With 55.9 months' follow-up, postoperative lymphedema was diagnosed in 94 patients (19.7 percent). Reconstruction patients developed lymphedema in 19.2 percent of cases versus 20.1 percent for no- reconstruction patients (p = 0.82). Regression identified two independent predictors of lymphedema: postoperative radiation therapy (OR, 2.90; p < 0.001) and obesity (OR, 2.36; p < 0.001).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">This study demonstrates a 19.7 percent incidence of lymphedema following axillary lymphadenectomy. Reconstruction does not appear to alter lymphedema risk, whereas postoperative radiation therapy, obesity, and extensive axillary dissection greatly increase risk.</AbstractText>
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<RefSource>Plast Reconstr Surg. 2016 Apr;137(4):749e-750e</RefSource>
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<RefSource>Plast Reconstr Surg. 2016 Apr;137(4):750e-751e</RefSource>
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<name sortKey="Fosnot, Joshua" sort="Fosnot, Joshua" uniqKey="Fosnot J" first="Joshua" last="Fosnot">Joshua Fosnot</name>
<name sortKey="Kanchwala, Suhail K" sort="Kanchwala, Suhail K" uniqKey="Kanchwala S" first="Suhail K" last="Kanchwala">Suhail K. Kanchwala</name>
<name sortKey="Kovach, Stephen J" sort="Kovach, Stephen J" uniqKey="Kovach S" first="Stephen J" last="Kovach">Stephen J. Kovach</name>
<name sortKey="Serletti, Joseph M" sort="Serletti, Joseph M" uniqKey="Serletti J" first="Joseph M" last="Serletti">Joseph M. Serletti</name>
<name sortKey="Silvestre, Jason" sort="Silvestre, Jason" uniqKey="Silvestre J" first="Jason" last="Silvestre">Jason Silvestre</name>
<name sortKey="Tchou, Julia C" sort="Tchou, Julia C" uniqKey="Tchou J" first="Julia C" last="Tchou">Julia C. Tchou</name>
<name sortKey="Wu, Liza C" sort="Wu, Liza C" uniqKey="Wu L" first="Liza C" last="Wu">Liza C. Wu</name>
</noCountry>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 007677 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 007677 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    Ncbi
   |étape=   Merge
   |type=    RBID
   |clé=     pubmed:26218386
   |texte=   A Propensity-Matched Analysis of the Influence of Breast Reconstruction on Subsequent Development of Lymphedema.
}}

Pour générer des pages wiki

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       | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1 

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