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A rare case of delayed subarachnoid anesthetic blockade effects in a 103-year-old female patient

Identifieur interne : 007482 ( Ncbi/Merge ); précédent : 007481; suivant : 007483

A rare case of delayed subarachnoid anesthetic blockade effects in a 103-year-old female patient

Auteurs : Ramsis F. Ghaly [États-Unis] ; Utchariya Anantamongkol [États-Unis] ; Kenneth D. Candido [États-Unis] ; Nebojsa Nick Knezevic [États-Unis]

Source :

RBID : PMC:4448518

Abstract

Background:

The elderly represent a unique challenge for the effects of regional anesthesia, and very few cases of block onset delay have been described. Their delayed response is attributed to a number of factors that include: Physiologic deterioration, musculoskeletal contractures, degenerative joint disease, autonomic regulatory dysfunction, cognitive dysfunction, altered pharmacokinetics, and pharmacodynamics of local anesthetics and adjuvants.

Case Description:

In this report we present the rare case of 45-min delay between the administration and onset of action of a subarachnoid blockade in a 103-year-old female, who was scheduled for left hip pinning, for repair of a femoral neck fracture. Patient received an injection of hyperbaric bupivacaine, 1.5 ml of 0.75% (11.25 mg), with 15 mcg of fentanyl into the subarachnoidal space and underwent the surgical procedure without complications.

Conclusions:

Delayed responses to subarachnoid anesthesia can be expected in extremely elderly patients. Anesthetic procedures should be monitored and managed on a case-by-case basis.


Url:
DOI: 10.4103/2152-7806.157658
PubMed: 26060597
PubMed Central: 4448518

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PMC:4448518

Le document en format XML

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<p>In this report we present the rare case of 45-min delay between the administration and onset of action of a subarachnoid blockade in a 103-year-old female, who was scheduled for left hip pinning, for repair of a femoral neck fracture. Patient received an injection of hyperbaric bupivacaine, 1.5 ml of 0.75% (11.25 mg), with 15 mcg of fentanyl into the subarachnoidal space and underwent the surgical procedure without complications.</p>
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<journal-id journal-id-type="nlm-ta">Surg Neurol Int</journal-id>
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<contrib contrib-type="author">
<name>
<surname>Ghaly</surname>
<given-names>Ramsis F.</given-names>
</name>
<email xlink:href="rfghaly@aol.com">rfghaly@aol.com</email>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="aff" rid="aff2">2</xref>
<xref ref-type="aff" rid="aff3">3</xref>
<xref ref-type="aff" rid="aff4">4</xref>
<xref ref-type="corresp" rid="cor1">*</xref>
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<contrib contrib-type="author">
<name>
<surname>Anantamongkol</surname>
<given-names>Utchariya</given-names>
</name>
<email xlink:href="utchariya.anan@gmail.com">utchariya.anan@gmail.com</email>
<xref ref-type="aff" rid="aff1">1</xref>
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<contrib contrib-type="author">
<name>
<surname>Candido</surname>
<given-names>Kenneth D.</given-names>
</name>
<email xlink:href="kdcandido1@gmail.com">kdcandido1@gmail.com</email>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="aff" rid="aff4">4</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Knezevic</surname>
<given-names>Nebojsa Nick</given-names>
</name>
<email xlink:href="nick.knezevic@gmail.com">nick.knezevic@gmail.com</email>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="aff" rid="aff4">4</xref>
</contrib>
</contrib-group>
<aff id="aff1">
<label>1</label>
Department of Anesthesiology, Advocate Illinois Masonic Medical Center, Chicago, IL 60657</aff>
<aff id="aff2">
<label>2</label>
Department of Anesthesiology, JHS Hospital of Cook County, Chicago, IL 60612</aff>
<aff id="aff3">
<label>3</label>
Ghaly Neurosurgical Associates, Aurora, IL 60504</aff>
<aff id="aff4">
<label>4</label>
Department of Anesthesiology, University of Illinois, Chicago, IL 60612, USA</aff>
<author-notes>
<corresp id="cor1">
<label>*</label>
Corresponding author </corresp>
</author-notes>
<pub-date pub-type="collection">
<year>2015</year>
</pub-date>
<pub-date pub-type="epub">
<day>26</day>
<month>5</month>
<year>2015</year>
</pub-date>
<volume>6</volume>
<elocation-id>88</elocation-id>
<history>
<date date-type="received">
<day>27</day>
<month>2</month>
<year>2015</year>
</date>
<date date-type="accepted">
<day>17</day>
<month>3</month>
<year>2015</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright: © 2015 Ghaly RF.</copyright-statement>
<copyright-year>2015</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0">
<license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract>
<sec id="st1">
<title>Background:</title>
<p>The elderly represent a unique challenge for the effects of regional anesthesia, and very few cases of block onset delay have been described. Their delayed response is attributed to a number of factors that include: Physiologic deterioration, musculoskeletal contractures, degenerative joint disease, autonomic regulatory dysfunction, cognitive dysfunction, altered pharmacokinetics, and pharmacodynamics of local anesthetics and adjuvants.</p>
</sec>
<sec id="st2">
<title>Case Description:</title>
<p>In this report we present the rare case of 45-min delay between the administration and onset of action of a subarachnoid blockade in a 103-year-old female, who was scheduled for left hip pinning, for repair of a femoral neck fracture. Patient received an injection of hyperbaric bupivacaine, 1.5 ml of 0.75% (11.25 mg), with 15 mcg of fentanyl into the subarachnoidal space and underwent the surgical procedure without complications.</p>
</sec>
<sec id="st3">
<title>Conclusions:</title>
<p>Delayed responses to subarachnoid anesthesia can be expected in extremely elderly patients. Anesthetic procedures should be monitored and managed on a case-by-case basis.</p>
</sec>
</abstract>
<kwd-group>
<kwd>Delayed response</kwd>
<kwd>elderly patients</kwd>
<kwd>subarachnoid anesthetic blockade</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
<affiliations>
<list>
<country>
<li>États-Unis</li>
</country>
<region>
<li>Illinois</li>
</region>
</list>
<tree>
<country name="États-Unis">
<region name="Illinois">
<name sortKey="Ghaly, Ramsis F" sort="Ghaly, Ramsis F" uniqKey="Ghaly R" first="Ramsis F." last="Ghaly">Ramsis F. Ghaly</name>
</region>
<name sortKey="Anantamongkol, Utchariya" sort="Anantamongkol, Utchariya" uniqKey="Anantamongkol U" first="Utchariya" last="Anantamongkol">Utchariya Anantamongkol</name>
<name sortKey="Candido, Kenneth D" sort="Candido, Kenneth D" uniqKey="Candido K" first="Kenneth D." last="Candido">Kenneth D. Candido</name>
<name sortKey="Candido, Kenneth D" sort="Candido, Kenneth D" uniqKey="Candido K" first="Kenneth D." last="Candido">Kenneth D. Candido</name>
<name sortKey="Ghaly, Ramsis F" sort="Ghaly, Ramsis F" uniqKey="Ghaly R" first="Ramsis F." last="Ghaly">Ramsis F. Ghaly</name>
<name sortKey="Ghaly, Ramsis F" sort="Ghaly, Ramsis F" uniqKey="Ghaly R" first="Ramsis F." last="Ghaly">Ramsis F. Ghaly</name>
<name sortKey="Knezevic, Nebojsa Nick" sort="Knezevic, Nebojsa Nick" uniqKey="Knezevic N" first="Nebojsa Nick" last="Knezevic">Nebojsa Nick Knezevic</name>
<name sortKey="Knezevic, Nebojsa Nick" sort="Knezevic, Nebojsa Nick" uniqKey="Knezevic N" first="Nebojsa Nick" last="Knezevic">Nebojsa Nick Knezevic</name>
</country>
</tree>
</affiliations>
</record>

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