The primary management of breast cancer: is breast conservation feasible for all patients?
Identifieur interne : 007460 ( Ncbi/Merge ); précédent : 007459; suivant : 007461The primary management of breast cancer: is breast conservation feasible for all patients?
Auteurs : L. C. Barr ; A. M. Brunt ; A. G. Goodman ; A. Drury ; R. H. Phillips ; H. EllisSource :
- Annals of The Royal College of Surgeons of England [ 0035-8843 ] ; 1989.
Abstract
A consecutive series of 411 patients with primary breast cancer treated by a consistent policy of breast conservation, regardless of tumour size, location, clinical stage or histological subtype, is reported. Actuarial 5-year survival was 84% for UICC Stage I, 73% for Stage II and 47% for Stage III/IV. The incidence of local recurrence at 5 years was 13% for Stage I, 12% for Stage II, and 26% for Stage III/IV. The probability of salvage mastectomy at 5 years was 5% for Stage I, 8% for Stage II, and 15% for Stage III/IV. Of local recurrences, 40% were managed with further breast conservation. Primary treatment with breast conservation results in satisfactory local control rates, 5-year survival and cosmesis, but the prevention, diagnosis and treatment of local recurrence within the conserved breast requires further evaluation.
Url:
PubMed: 2604349
PubMed Central: 2499051
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PMC:2499051Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The primary management of breast cancer: is breast conservation feasible for all patients?</title>
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<series><title level="j">Annals of The Royal College of Surgeons of England</title>
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<front><div type="abstract" xml:lang="en"><p>A consecutive series of 411 patients with primary breast cancer treated by a consistent policy of breast conservation, regardless of tumour size, location, clinical stage or histological subtype, is reported. Actuarial 5-year survival was 84% for UICC Stage I, 73% for Stage II and 47% for Stage III/IV. The incidence of local recurrence at 5 years was 13% for Stage I, 12% for Stage II, and 26% for Stage III/IV. The probability of salvage mastectomy at 5 years was 5% for Stage I, 8% for Stage II, and 15% for Stage III/IV. Of local recurrences, 40% were managed with further breast conservation. Primary treatment with breast conservation results in satisfactory local control rates, 5-year survival and cosmesis, but the prevention, diagnosis and treatment of local recurrence within the conserved breast requires further evaluation.</p>
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<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Ann R Coll Surg Engl</journal-id>
<journal-id journal-id-type="pmc">annrcse</journal-id>
<journal-title>Annals of The Royal College of Surgeons of England</journal-title>
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<article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject>
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<title-group><article-title>The primary management of breast cancer: is breast conservation feasible for all patients?</article-title>
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<contrib-group><contrib contrib-type="author"><name><surname>Barr</surname>
<given-names>L. C.</given-names>
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<contrib contrib-type="author"><name><surname>Brunt</surname>
<given-names>A. M.</given-names>
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<contrib contrib-type="author"><name><surname>Goodman</surname>
<given-names>A. G.</given-names>
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<contrib contrib-type="author"><name><surname>Drury</surname>
<given-names>A.</given-names>
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<contrib contrib-type="author"><name><surname>Phillips</surname>
<given-names>R. H.</given-names>
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<contrib contrib-type="author"><name><surname>Ellis</surname>
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<aff>Academic Surgical Unit, Westminster Hospital, London.</aff>
<pub-date pub-type="ppub"><month>11</month>
<year>1989</year>
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<volume>71</volume>
<issue>6</issue>
<fpage>390</fpage>
<lpage>393</lpage>
<abstract><p>A consecutive series of 411 patients with primary breast cancer treated by a consistent policy of breast conservation, regardless of tumour size, location, clinical stage or histological subtype, is reported. Actuarial 5-year survival was 84% for UICC Stage I, 73% for Stage II and 47% for Stage III/IV. The incidence of local recurrence at 5 years was 13% for Stage I, 12% for Stage II, and 26% for Stage III/IV. The probability of salvage mastectomy at 5 years was 5% for Stage I, 8% for Stage II, and 15% for Stage III/IV. Of local recurrences, 40% were managed with further breast conservation. Primary treatment with breast conservation results in satisfactory local control rates, 5-year survival and cosmesis, but the prevention, diagnosis and treatment of local recurrence within the conserved breast requires further evaluation.</p>
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<name sortKey="Drury, A" sort="Drury, A" uniqKey="Drury A" first="A." last="Drury">A. Drury</name>
<name sortKey="Ellis, H" sort="Ellis, H" uniqKey="Ellis H" first="H." last="Ellis">H. Ellis</name>
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<name sortKey="Phillips, R H" sort="Phillips, R H" uniqKey="Phillips R" first="R. H." last="Phillips">R. H. Phillips</name>
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