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A Case Report of Turner Syndrome with Graves’ Disease during Recombinant Human GH Therapy and Review of Literature

Identifieur interne : 006628 ( Ncbi/Merge ); précédent : 006627; suivant : 006629

A Case Report of Turner Syndrome with Graves’ Disease during Recombinant Human GH Therapy and Review of Literature

Auteurs : Makio Nakagawa ; Yasuji Inamo ; Kensuke Harada

Source :

RBID : PMC:4004847

Abstract

An increased incidence of Hashimoto thyroiditis has been reported in patients with Turner syndrome, but several cases of Graves’ disease were also described ten to 20 years ago. We report the case of a patient with Turner syndrome who developed Graves’ disease, 3 years after successful treatment with recombinant human growth hormone (GH). A diagnosis of Graves’ disease was made and treatment with thiamazole was started, which resulted in normalization of the thyroid function. It is important to monitor thyroid function as well as growth parameters in patients with Turner syndrome.


Url:
DOI: 10.1297/cpe.15.55
PubMed: 24790321
PubMed Central: 4004847

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PMC:4004847

Le document en format XML

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<name sortKey="Inamo, Yasuji" sort="Inamo, Yasuji" uniqKey="Inamo Y" first="Yasuji" last="Inamo">Yasuji Inamo</name>
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<p> An increased incidence of Hashimoto thyroiditis has been reported in patients with Turner syndrome, but several cases of Graves’ disease were also described ten to 20 years ago. We report the case of a patient with Turner syndrome who developed Graves’ disease, 3 years after successful treatment with recombinant human growth hormone (GH). A diagnosis of Graves’ disease was made and treatment with thiamazole was started, which resulted in normalization of the thyroid function. It is important to monitor thyroid function as well as growth parameters in patients with Turner syndrome.</p>
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<aff id="aff1">Department of General Pediatrics, Nerima-Hikarigaoka Nihon University Hospital, Nihon University School of Medicine, Tokyo, Japan</aff>
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<corresp id="cor">Correspondence: Dr. Yasuji Inamo, Department of General Pediatrics, Nerima-Hikarigaoka Nihon University Hospital, Nihon University School of Medicine, 2-11-1, Hikarigaoka, Nerima-ku, Tokyo 179-0072, Japan. E-mail:
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<p> An increased incidence of Hashimoto thyroiditis has been reported in patients with Turner syndrome, but several cases of Graves’ disease were also described ten to 20 years ago. We report the case of a patient with Turner syndrome who developed Graves’ disease, 3 years after successful treatment with recombinant human growth hormone (GH). A diagnosis of Graves’ disease was made and treatment with thiamazole was started, which resulted in normalization of the thyroid function. It is important to monitor thyroid function as well as growth parameters in patients with Turner syndrome.</p>
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