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Oncological outcome and long-term complications in robot-assisted radical surgery for early stage cervical cancer: an observational cohort study.

Identifieur interne : 006575 ( Ncbi/Merge ); précédent : 006574; suivant : 006576

Oncological outcome and long-term complications in robot-assisted radical surgery for early stage cervical cancer: an observational cohort study.

Auteurs : J P Hoogendam [Pays-Bas] ; R H M. Verheijen ; I. Wegner ; R P Zweemer

Source :

RBID : pubmed:24735243

Descripteurs français

English descriptors

Abstract

To report the oncological outcome and long-term complications of radical surgery by robot-assisted laparoscopy in early stage cervical cancer.

DOI: 10.1111/1471-0528.12822
PubMed: 24735243

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pubmed:24735243

Le document en format XML

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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
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<term>Humans</term>
<term>Hysterectomy (methods)</term>
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<term>Lymph Node Excision (methods)</term>
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<term>Retrospective Studies</term>
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<term>Treatment Outcome</term>
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<term>Adulte</term>
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<term>Adénocarcinome</term>
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<div type="abstract" xml:lang="en">To report the oncological outcome and long-term complications of radical surgery by robot-assisted laparoscopy in early stage cervical cancer.</div>
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<Month>10</Month>
<Day>28</Day>
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<Month>12</Month>
<Day>24</Day>
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<Day>28</Day>
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<Month>Nov</Month>
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<Title>BJOG : an international journal of obstetrics and gynaecology</Title>
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<ArticleTitle>Oncological outcome and long-term complications in robot-assisted radical surgery for early stage cervical cancer: an observational cohort study.</ArticleTitle>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To report the oncological outcome and long-term complications of radical surgery by robot-assisted laparoscopy in early stage cervical cancer.</AbstractText>
<AbstractText Label="DESIGN" NlmCategory="METHODS">Observational cohort study.</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">Tertiary referral centre.</AbstractText>
<AbstractText Label="POPULATION" NlmCategory="METHODS">About 100 cervical cancer patients treated consecutively with robot-assisted radical surgery between 2008 and 2013.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Two gynaecological oncologists specialised in minimally invasive surgery performed all surgeries on a three/four-armed robotic system. Procedures consisted of pelvic lymph node dissection combined with a radical hysterectomy, radical vaginal trachelectomy or parametrectomy.</AbstractText>
<AbstractText Label="MAIN OUTCOME MEASURES" NlmCategory="METHODS">Recurrence, survival and long-term complication rates.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">104 robot-assisted laparoscopies were performed in 100 patients (stage IA1-IIB), with a median follow-up of 29.5 months (range 2.5-67.1 months). Thirteen cases were diagnosed with a loco-regional (8%), distant (4%) or combined (1%) recurrence at a median of 14.4 months (range 2.9-34.8 months). All mortality (7%) was cervical cancer-related and due to recurrent disease. Four recurrences receive palliative care and two are in complete remission. The overall 5-year progression-free and disease-specific survival rates are 81.4 and 88.7%, respectively. Frequent complications were lymphoedema (26%), lower urinary tract symptoms (19%), urinary tract infection (17%) and sexual disorders (9%). Five patients had a vaginal cuff dehiscence. No complication-related mortality occurred.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The recurrence, survival and long-term complication rates of robot-assisted radical surgery for early stage cervical cancer in this cohort are reassuring concerning its continued clinical use.</AbstractText>
<CopyrightInformation>© 2014 Royal College of Obstetricians and Gynaecologists.</CopyrightInformation>
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<Language>eng</Language>
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<ArticleDate DateType="Electronic">
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<Month>04</Month>
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<MeshHeading>
<DescriptorName UI="D000230" MajorTopicYN="N">Adenocarcinoma</DescriptorName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
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<Keyword MajorTopicYN="N">Cervical cancer</Keyword>
<Keyword MajorTopicYN="N">complications</Keyword>
<Keyword MajorTopicYN="N">recurrence</Keyword>
<Keyword MajorTopicYN="N">robot-assisted laparoscopy</Keyword>
<Keyword MajorTopicYN="N">survival</Keyword>
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