Serveur d'exploration sur le lymphœdème

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Peripheral lymphovenous communication in lymphoedema.

Identifieur interne : 004C66 ( Ncbi/Merge ); précédent : 004C65; suivant : 004C67

Peripheral lymphovenous communication in lymphoedema.

Auteurs : Gregory Francis William Stamp [Royaume-Uni] ; Adrien Michael Peters

Source :

RBID : pubmed:22495080

Descripteurs français

English descriptors

Abstract

To investigate whether in lower extremity lymphoedema, lymph proteins enter blood before they do the thoracic duct.

DOI: 10.1097/MNM.0b013e32835313d4
PubMed: 22495080

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pubmed:22495080

Le document en format XML

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<title xml:lang="en">Peripheral lymphovenous communication in lymphoedema.</title>
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<name sortKey="Stamp, Gregory Francis William" sort="Stamp, Gregory Francis William" uniqKey="Stamp G" first="Gregory Francis William" last="Stamp">Gregory Francis William Stamp</name>
<affiliation wicri:level="1">
<nlm:affiliation>Brighton and Sussex Medical School, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Brighton and Sussex Medical School</wicri:regionArea>
</affiliation>
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<author>
<name sortKey="Peters, Adrien Michael" sort="Peters, Adrien Michael" uniqKey="Peters A" first="Adrien Michael" last="Peters">Adrien Michael Peters</name>
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<title xml:lang="en">Peripheral lymphovenous communication in lymphoedema.</title>
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<name sortKey="Stamp, Gregory Francis William" sort="Stamp, Gregory Francis William" uniqKey="Stamp G" first="Gregory Francis William" last="Stamp">Gregory Francis William Stamp</name>
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<nlm:affiliation>Brighton and Sussex Medical School, UK.</nlm:affiliation>
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<name sortKey="Peters, Adrien Michael" sort="Peters, Adrien Michael" uniqKey="Peters A" first="Adrien Michael" last="Peters">Adrien Michael Peters</name>
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<title level="j">Nuclear medicine communications</title>
<idno type="eISSN">1473-5628</idno>
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<term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Blood Proteins (analysis)</term>
<term>Case-Control Studies</term>
<term>Humans</term>
<term>Liver (diagnostic imaging)</term>
<term>Lymphedema (diagnostic imaging)</term>
<term>Lymphoscintigraphy (methods)</term>
<term>Middle Aged</term>
<term>Organotechnetium Compounds</term>
<term>Retrospective Studies</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Composés organiques du technétium</term>
<term>Foie (imagerie diagnostique)</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Lymphoedème (imagerie diagnostique)</term>
<term>Lymphoscintigraphie ()</term>
<term>Protéines du sang (analyse)</term>
<term>Sujet âgé</term>
<term>Études cas-témoins</term>
<term>Études rétrospectives</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en">
<term>Blood Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="analyse" xml:lang="fr">
<term>Protéines du sang</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en">
<term>Liver</term>
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr">
<term>Foie</term>
<term>Lymphoedème</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Lymphoscintigraphy</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Case-Control Studies</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Organotechnetium Compounds</term>
<term>Retrospective Studies</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Composés organiques du technétium</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Lymphoscintigraphie</term>
<term>Sujet âgé</term>
<term>Études cas-témoins</term>
<term>Études rétrospectives</term>
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<front>
<div type="abstract" xml:lang="en">To investigate whether in lower extremity lymphoedema, lymph proteins enter blood before they do the thoracic duct.</div>
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<DateCreated>
<Year>2012</Year>
<Month>06</Month>
<Day>04</Day>
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<DateCompleted>
<Year>2012</Year>
<Month>09</Month>
<Day>18</Day>
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<DateRevised>
<Year>2016</Year>
<Month>11</Month>
<Day>25</Day>
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<ISSN IssnType="Electronic">1473-5628</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>33</Volume>
<Issue>7</Issue>
<PubDate>
<Year>2012</Year>
<Month>Jul</Month>
</PubDate>
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<Title>Nuclear medicine communications</Title>
<ISOAbbreviation>Nucl Med Commun</ISOAbbreviation>
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<ArticleTitle>Peripheral lymphovenous communication in lymphoedema.</ArticleTitle>
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<ELocationID EIdType="doi" ValidYN="Y">10.1097/MNM.0b013e32835313d4</ELocationID>
<Abstract>
<AbstractText Label="AIM" NlmCategory="OBJECTIVE">To investigate whether in lower extremity lymphoedema, lymph proteins enter blood before they do the thoracic duct.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Retrospective analysis of routine lymphoscintigraphy in 69 adults imaged at 5, 45 and 150 min following bilateral subcutaneous web space injection of Tc-nanocolloid was carried out. Regions of interest were placed over the liver and ilioinguinal lymph nodes bilaterally on the anterior images at 45 and 150 min. Individual minor (0.5 point for each) and major (1 point for each) criteria of abnormal scintigraphy were applied to each limb and summed to give a lymphoscintigraphic abnormality score. An abnormal limb had a score ≥1.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The ratio of hepatic counts per pixel to total bilateral ilioinguinal counts (L/N ratio) was higher in patients with abnormal results on lymphoscintigraphy (median 6.2; interquartile range 4.0-15.6 pixels×10; n=48) compared with that in patients with normal lymphoscintigraphic results (2.5 [1.5-5.0] pixels×10; n=21; P<0.0002). In the abnormal group, the lymphoscintigraphic score (two limbs summed) correlated with the 150-min L/N ratio (r s=0.42; P<0.005). L/N ratios at 45 and 150 min correlated in the abnormal group (r s=0.44; P<0.005) but not in the normal group (r s=0.3; P>0.05). The 45-min activity, as a percentage of the 150-min activity, was higher in lymph nodes than in the liver in both the abnormal (35.0 [8.2-50.0] vs. 10.6 [5.8-30.0]%; P<0.0001]) and normal groups (38.3 [18.4-63.5] vs. 23.3 [12.4-33.1]%; P<0.05), and, with respect to the liver, was higher in the normal group (P<0.01).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">In lymphoedema, more lymph proteins enter blood proximal to the thoracic duct. The time courses of nodal and hepatic activities suggest that access may occur within nodes themselves.</AbstractText>
</Abstract>
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<DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
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<DescriptorName UI="D008099" MajorTopicYN="N">Liver</DescriptorName>
<QualifierName UI="Q000000981" MajorTopicYN="Y">diagnostic imaging</QualifierName>
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<DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName>
<QualifierName UI="Q000000981" MajorTopicYN="Y">diagnostic imaging</QualifierName>
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<DescriptorName UI="D061305" MajorTopicYN="N">Lymphoscintigraphy</DescriptorName>
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<DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
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<DescriptorName UI="D015609" MajorTopicYN="N">Organotechnetium Compounds</DescriptorName>
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<DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName>
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