Thoracic aorta pseudoaneurysm with hemopericardium: unusual presentation of warfarin overdose
Identifieur interne : 004304 ( Ncbi/Merge ); précédent : 004303; suivant : 004305Thoracic aorta pseudoaneurysm with hemopericardium: unusual presentation of warfarin overdose
Auteurs : Ya-Chih Tien [Taïwan] ; Ying-Cheng Chen [Taïwan] ; Chiung-Ying Liao [Taïwan] ; Chia-Chu Chang [Taïwan]Source :
- Journal of Occupational Medicine and Toxicology (London, England) [ 1745-6673 ] ; 2011.
Abstract
There have been few case reports which discuss a relationship between warfarin overdose and aortic pseudoaneurysm leakage. We report the case of a female receiving warfarin who presented with dsypnea. Her international normalized ratio was > 10. Chest radiograph revealed cardiomegaly, and chest computed tomography (CT) showed a bulging pouch-like lesion below the aortic arch greater than 6x6 cm in size and a fluid collection suggesting blood in the pericardium. Thoracic endovascular aneurysm repair (TEVAR) was successfully performed by a cardiovascular surgeon. Aortic pseudoaneurysm formation and leakage may be considered as a rare complication in patients receiving warfarin therapy. Further study regarding warfarin use and the incidence of pseudoaneurysm leakage is needed.
Url:
DOI: 10.1186/1745-6673-6-12
PubMed: 21521519
PubMed Central: 3114796
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Surgery, Changhua Christian Hospital, 135 Nan-Siau Street, Changhua city, 500 Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Cardiovascular Surgery, Changhua Christian Hospital, 135 Nan-Siau Street, Changhua city</wicri:regionArea><wicri:noRegion>Changhua city</wicri:noRegion></affiliation></author><author><name sortKey="Liao, Chiung Ying" sort="Liao, Chiung Ying" uniqKey="Liao C" first="Chiung-Ying" last="Liao">Chiung-Ying Liao</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Radiology, Changhua Christian Hospital, 135 Nan-Siau Street, Changhua city, 500 Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Radiology, Changhua Christian Hospital, 135 Nan-Siau Street, Changhua city</wicri:regionArea><wicri:noRegion>Changhua city</wicri:noRegion></affiliation></author><author><name sortKey="Chang, Chia Chu" sort="Chang, Chia Chu" uniqKey="Chang C" first="Chia-Chu" last="Chang">Chia-Chu Chang</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Medicine, Changhua Christian Hospital, 135 Nan-Siau Street, Changhua city, 500 Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Medicine, Changhua Christian Hospital, 135 Nan-Siau Street, Changhua city</wicri:regionArea><wicri:noRegion>Changhua city</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of Occupational Medicine and Toxicology (London, England)</title><idno type="eISSN">1745-6673</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>There have been few case reports which discuss a relationship between warfarin overdose and aortic pseudoaneurysm leakage. We report the case of a female receiving warfarin who presented with dsypnea. Her international normalized ratio was > 10. Chest radiograph revealed cardiomegaly, and chest computed tomography (CT) showed a bulging pouch-like lesion below the aortic arch greater than 6x6 cm in size and a fluid collection suggesting blood in the pericardium. Thoracic endovascular aneurysm repair (TEVAR) was successfully performed by a cardiovascular surgeon. Aortic pseudoaneurysm formation and leakage may be considered as a rare complication in patients receiving warfarin therapy. Further study regarding warfarin use and the incidence of pseudoaneurysm leakage is needed.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Dumont, E" uniqKey="Dumont E">E Dumont</name></author><author><name sortKey="Carrier, M" uniqKey="Carrier M">M Carrier</name></author><author><name sortKey="Cartier, R" uniqKey="Cartier R">R Cartier</name></author><author><name sortKey="Pellerin, M" uniqKey="Pellerin M">M Pellerin</name></author><author><name sortKey="Poirier, N" uniqKey="Poirier N">N Poirier</name></author><author><name sortKey="Bouchard, D" uniqKey="Bouchard D">D Bouchard</name></author><author><name sortKey="Perrault, Lp" uniqKey="Perrault L">LP Perrault</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tammelin, A" uniqKey="Tammelin A">A Tammelin</name></author><author><name sortKey="Hambraeus, A" uniqKey="Hambraeus A">A Hambraeus</name></author><author><name sortKey="Stahle, E" uniqKey="Stahle E">E Stahle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Atik, Fa" uniqKey="Atik F">FA Atik</name></author><author><name sortKey="Navia, Jl" uniqKey="Navia J">JL Navia</name></author><author><name sortKey="Svensson, Lg" uniqKey="Svensson L">LG Svensson</name></author><author><name sortKey="Vega P, R" uniqKey="Vega P R">R Vega P</name></author><author><name sortKey="Feng, J" uniqKey="Feng J">J Feng</name></author><author><name sortKey="Brizzio, Me" uniqKey="Brizzio M">ME Brizzio</name></author><author><name sortKey="Gillinov, Am" uniqKey="Gillinov A">AM Gillinov</name></author><author><name sortKey="Pettersson, Bg" uniqKey="Pettersson B">BG Pettersson</name></author><author><name sortKey="Blackstone, Eh" uniqKey="Blackstone E">EH Blackstone</name></author><author><name sortKey="Lytle, Bw" uniqKey="Lytle B">BW Lytle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Davidm, M" uniqKey="Davidm M">M Davidm</name></author><author><name sortKey="Tthomaps, P" uniqKey="Tthomaps P">P Tthomaps</name></author><author><name sortKey="Sinda, B" uniqKey="Sinda B">B Sinda</name></author><author><name sortKey="Robert, L" uniqKey="Robert L">L Robert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sozen, D" uniqKey="Sozen D">D Sozen</name></author><author><name sortKey="Ahmet, M" uniqKey="Ahmet M">M Ahmet</name></author><author><name sortKey="Arzum, K" uniqKey="Arzum K">K Arzum</name></author><author><name sortKey="Suat, B" uniqKey="Suat B">B Suat</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Enrico, T" uniqKey="Enrico T">T Enrico</name></author><author><name sortKey="Fausto, M" uniqKey="Fausto M">M Fausto</name></author><author><name sortKey="Lorenzo, M" uniqKey="Lorenzo M">M Lorenzo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Blunt, Dm" uniqKey="Blunt D">DM Blunt</name></author><author><name sortKey="Implloment, Mg" uniqKey="Implloment M">MG Implloment</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Der Meer, Fjm" uniqKey="Van Der Meer F">FJM Van der Meer</name></author><author><name sortKey="Rosendaal, Fr" uniqKey="Rosendaal F">FR Rosendaal</name></author><author><name sortKey="Vanderbouke, Be" uniqKey="Vanderbouke B">BE Vanderbouke</name></author><author><name sortKey="Briet, E" uniqKey="Briet E">E Briët</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Occup Med Toxicol</journal-id><journal-title-group><journal-title>Journal of Occupational Medicine and Toxicology (London, England)</journal-title></journal-title-group><issn pub-type="epub">1745-6673</issn><publisher><publisher-name>BioMed Central</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">21521519</article-id><article-id pub-id-type="pmc">3114796</article-id><article-id pub-id-type="publisher-id">1745-6673-6-12</article-id><article-id pub-id-type="doi">10.1186/1745-6673-6-12</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>Thoracic aorta pseudoaneurysm with hemopericardium: unusual presentation of warfarin overdose</article-title></title-group><contrib-group><contrib contrib-type="author" id="A1"><name><surname>Tien</surname><given-names>Ya-Chih</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>143973@cch.org.tw</email></contrib><contrib contrib-type="author" id="A2"><name><surname>Chen</surname><given-names>Ying-Cheng</given-names></name><xref ref-type="aff" rid="I2">2</xref><email>137448@cch.org.tw</email></contrib><contrib contrib-type="author" id="A3"><name><surname>Liao</surname><given-names>Chiung-Ying</given-names></name><xref ref-type="aff" rid="I3">3</xref><email>84969@cch.org.tw</email></contrib><contrib contrib-type="author" corresp="yes" id="A4"><name><surname>Chang</surname><given-names>Chia-Chu</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>27509@cch.org.tw</email></contrib></contrib-group><aff id="I1"><label>1</label>Department of Medicine, Changhua Christian Hospital, 135 Nan-Siau Street, Changhua city, 500 Taiwan</aff><aff id="I2"><label>2</label>Department of Cardiovascular Surgery, Changhua Christian Hospital, 135 Nan-Siau Street, Changhua city, 500 Taiwan</aff><aff id="I3"><label>3</label>Department of Radiology, Changhua Christian Hospital, 135 Nan-Siau Street, Changhua city, 500 Taiwan</aff><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>26</day><month>4</month><year>2011</year></pub-date><volume>6</volume><fpage>12</fpage><lpage>12</lpage><history><date date-type="received"><day>5</day><month>11</month><year>2010</year></date><date date-type="accepted"><day>26</day><month>4</month><year>2011</year></date></history><permissions><copyright-statement>Copyright ©2011 Tien et al; licensee BioMed Central Ltd.</copyright-statement><copyright-year>2011</copyright-year><copyright-holder>Tien et al; licensee BioMed Central Ltd.</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/2.0"><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/2.0">http://creativecommons.org/licenses/by/2.0</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><self-uri xlink:href="http://www.occup-med.com/content/6/1/12"></self-uri><abstract><p>There have been few case reports which discuss a relationship between warfarin overdose and aortic pseudoaneurysm leakage. We report the case of a female receiving warfarin who presented with dsypnea. Her international normalized ratio was > 10. Chest radiograph revealed cardiomegaly, and chest computed tomography (CT) showed a bulging pouch-like lesion below the aortic arch greater than 6x6 cm in size and a fluid collection suggesting blood in the pericardium. Thoracic endovascular aneurysm repair (TEVAR) was successfully performed by a cardiovascular surgeon. Aortic pseudoaneurysm formation and leakage may be considered as a rare complication in patients receiving warfarin therapy. Further study regarding warfarin use and the incidence of pseudoaneurysm leakage is needed.</p></abstract><kwd-group><kwd>Warfarin</kwd><kwd>pseudoaneurysm</kwd><kwd>hemopericardium</kwd><kwd>TEVAR</kwd></kwd-group></article-meta></front></pmc><affiliations><list><country><li>Taïwan</li></country></list><tree><country name="Taïwan"><noRegion><name sortKey="Tien, Ya Chih" sort="Tien, Ya Chih" uniqKey="Tien Y" first="Ya-Chih" last="Tien">Ya-Chih Tien</name></noRegion><name sortKey="Chang, Chia Chu" sort="Chang, Chia Chu" uniqKey="Chang C" first="Chia-Chu" last="Chang">Chia-Chu Chang</name><name sortKey="Chen, Ying Cheng" sort="Chen, Ying Cheng" uniqKey="Chen Y" first="Ying-Cheng" last="Chen">Ying-Cheng Chen</name><name sortKey="Liao, Chiung Ying" sort="Liao, Chiung Ying" uniqKey="Liao C" first="Chiung-Ying" last="Liao">Chiung-Ying Liao</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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