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Vulvar lymphoedematous pseudotumours mistaken for aggressive angiomyxoma: report of two cases.

Identifieur interne : 003863 ( Ncbi/Merge ); précédent : 003862; suivant : 003864

Vulvar lymphoedematous pseudotumours mistaken for aggressive angiomyxoma: report of two cases.

Auteurs : Antonio D'Antonio [Italie] ; Alessia Caleo ; Amedeo Boscaino ; Gennaro Mossetti ; Nicola Iannantuoni

Source :

RBID : pubmed:20068325

Descripteurs français

English descriptors

Abstract

We describe 2 cases of vulvar pseudotumour due to lymphatic obstruction with chronic lymphoedema of unknown cause that presented as a solitary mass that mimicked aggressive angiomyxoma.

DOI: 10.1159/000274467
PubMed: 20068325

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pubmed:20068325

Le document en format XML

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<title xml:lang="en">Vulvar lymphoedematous pseudotumours mistaken for aggressive angiomyxoma: report of two cases.</title>
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<name sortKey="D Antonio, Antonio" sort="D Antonio, Antonio" uniqKey="D Antonio A" first="Antonio" last="D'Antonio">Antonio D'Antonio</name>
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<nlm:affiliation>AUO San Giovanni di Dio e Ruggi d'Aragona, Salerno, Italy. ada66 @ inwind.it</nlm:affiliation>
<country xml:lang="fr">Italie</country>
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<name sortKey="Caleo, Alessia" sort="Caleo, Alessia" uniqKey="Caleo A" first="Alessia" last="Caleo">Alessia Caleo</name>
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<name sortKey="Boscaino, Amedeo" sort="Boscaino, Amedeo" uniqKey="Boscaino A" first="Amedeo" last="Boscaino">Amedeo Boscaino</name>
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<name sortKey="Mossetti, Gennaro" sort="Mossetti, Gennaro" uniqKey="Mossetti G" first="Gennaro" last="Mossetti">Gennaro Mossetti</name>
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<name sortKey="Iannantuoni, Nicola" sort="Iannantuoni, Nicola" uniqKey="Iannantuoni N" first="Nicola" last="Iannantuoni">Nicola Iannantuoni</name>
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<term>Adult</term>
<term>Biopsy</term>
<term>Diagnosis, Differential</term>
<term>Female</term>
<term>Humans</term>
<term>Lymphatic Vessels (pathology)</term>
<term>Lymphedema (pathology)</term>
<term>Lymphedema (surgery)</term>
<term>Middle Aged</term>
<term>Myxoma (pathology)</term>
<term>Vulva (pathology)</term>
<term>Vulva (surgery)</term>
<term>Vulvar Diseases (pathology)</term>
<term>Vulvar Diseases (surgery)</term>
<term>Vulvar Neoplasms (pathology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Biopsie</term>
<term>Diagnostic différentiel</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème ()</term>
<term>Lymphoedème (anatomopathologie)</term>
<term>Maladies de la vulve ()</term>
<term>Maladies de la vulve (anatomopathologie)</term>
<term>Myxome (anatomopathologie)</term>
<term>Tumeurs de la vulve (anatomopathologie)</term>
<term>Vaisseaux lymphatiques (anatomopathologie)</term>
<term>Vulve ()</term>
<term>Vulve (anatomopathologie)</term>
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<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr">
<term>Lymphoedème</term>
<term>Maladies de la vulve</term>
<term>Myxome</term>
<term>Tumeurs de la vulve</term>
<term>Vaisseaux lymphatiques</term>
<term>Vulve</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Lymphatic Vessels</term>
<term>Lymphedema</term>
<term>Myxoma</term>
<term>Vulva</term>
<term>Vulvar Diseases</term>
<term>Vulvar Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Lymphedema</term>
<term>Vulva</term>
<term>Vulvar Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
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<term>Biopsy</term>
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<term>Humans</term>
<term>Middle Aged</term>
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<term>Adulte d'âge moyen</term>
<term>Biopsie</term>
<term>Diagnostic différentiel</term>
<term>Femelle</term>
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<term>Lymphoedème</term>
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<div type="abstract" xml:lang="en">We describe 2 cases of vulvar pseudotumour due to lymphatic obstruction with chronic lymphoedema of unknown cause that presented as a solitary mass that mimicked aggressive angiomyxoma.</div>
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<Month>07</Month>
<Day>09</Day>
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<Title>Gynecologic and obstetric investigation</Title>
<ISOAbbreviation>Gynecol. Obstet. Invest.</ISOAbbreviation>
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<ArticleTitle>Vulvar lymphoedematous pseudotumours mistaken for aggressive angiomyxoma: report of two cases.</ArticleTitle>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">We describe 2 cases of vulvar pseudotumour due to lymphatic obstruction with chronic lymphoedema of unknown cause that presented as a solitary mass that mimicked aggressive angiomyxoma.</AbstractText>
<AbstractText Label="MATERIAL AND METHODS" NlmCategory="METHODS">Both patients presented with a vulvar mass without medical history of trauma, surgery in the anogenital region or skin diseases. One patient was overweight (BMI = 26). Both surgically resected vulvar specimens were represented by a polypoid mass with a soft and a gelatinous cut surface.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Histologically, the presence of an abundant oedematous stroma with spindle-shaped cells and numerous thin-walled small-to-medium vessels may be confused with an aggressive angiomyxoma. The diagnostic key was represented by the massive oedema, rather than myxoid stroma, with the presence of dilated, tortuous lymphatic channels (some surrounded by clusters of lymphocytes) in the dermis.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The recognition of these lesions is important because they may be the cause of problems in differential diagnosis and therapeutic management. In fact, such lesions can be mistaken from both the clinical and histological perspective as a primitive tumour of the vulva-like aggressive angiomyxoma. However, these lesions are not true neoplasms and are likely due to lymphatic obstruction with lymphoedema. A simple surgical excision with vulvoplasty is curative.</AbstractText>
<CopyrightInformation>Copyright 2009 S. Karger AG, Basel.</CopyrightInformation>
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