Serveur d'exploration sur le lymphœdème

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MR imaging of the lymphatic system in patients with lipedema and lipo-lymphedema.

Identifieur interne : 003327 ( Ncbi/Merge ); précédent : 003326; suivant : 003328

MR imaging of the lymphatic system in patients with lipedema and lipo-lymphedema.

Auteurs : Christian Lohrmann [Allemagne] ; Etelka Foeldi ; Mathias Langer

Source :

RBID : pubmed:19323976

Descripteurs français

English descriptors

Abstract

To assess for the first time the morphology of the lymphatic system in patients with lipedema and lipo-lymphedema of the lower extremities by MR lymphangiography.

DOI: 10.1016/j.mvr.2009.01.005
PubMed: 19323976

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pubmed:19323976

Le document en format XML

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<nlm:affiliation>Department of Radiology, University Hospital of Freiburg, Hugstetter Strasse 55, D-79106, Freiburg i. Br., Germany. christian.lohrmann@uniklinik-freiburg.de</nlm:affiliation>
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<name sortKey="Foeldi, Etelka" sort="Foeldi, Etelka" uniqKey="Foeldi E" first="Etelka" last="Foeldi">Etelka Foeldi</name>
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<term>Adipose Tissue (pathology)</term>
<term>Adult</term>
<term>Aged</term>
<term>Anesthetics, Local</term>
<term>Contrast Media (administration & dosage)</term>
<term>Edema (pathology)</term>
<term>Female</term>
<term>Gadolinium</term>
<term>Heterocyclic Compounds (administration & dosage)</term>
<term>Humans</term>
<term>Injections, Intradermal</term>
<term>Lower Extremity</term>
<term>Lymphatic System (pathology)</term>
<term>Lymphedema (pathology)</term>
<term>Lymphography (methods)</term>
<term>Magnetic Resonance Angiography (methods)</term>
<term>Male</term>
<term>Mepivacaine</term>
<term>Middle Aged</term>
<term>Organometallic Compounds (administration & dosage)</term>
<term>Young Adult</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Anesthésiques locaux</term>
<term>Angiographie par résonance magnétique ()</term>
<term>Composés hétérocycliques (administration et posologie)</term>
<term>Composés organométalliques (administration et posologie)</term>
<term>Femelle</term>
<term>Gadolinium</term>
<term>Humains</term>
<term>Injections intradermiques</term>
<term>Jeune adulte</term>
<term>Lymphoedème (anatomopathologie)</term>
<term>Lymphographie ()</term>
<term>Membre inférieur</term>
<term>Mâle</term>
<term>Mépivacaïne</term>
<term>Oedème (anatomopathologie)</term>
<term>Produits de contraste (administration et posologie)</term>
<term>Sujet âgé</term>
<term>Système lymphatique (anatomopathologie)</term>
<term>Tissu adipeux (anatomopathologie)</term>
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<term>Contrast Media</term>
<term>Heterocyclic Compounds</term>
<term>Organometallic Compounds</term>
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<term>Anesthetics, Local</term>
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<term>Mepivacaine</term>
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<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr">
<term>Lymphoedème</term>
<term>Oedème</term>
<term>Système lymphatique</term>
<term>Tissu adipeux</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Lymphography</term>
<term>Magnetic Resonance Angiography</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Adipose Tissue</term>
<term>Edema</term>
<term>Lymphatic System</term>
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Injections, Intradermal</term>
<term>Lower Extremity</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Young Adult</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Anesthésiques locaux</term>
<term>Angiographie par résonance magnétique</term>
<term>Femelle</term>
<term>Gadolinium</term>
<term>Humains</term>
<term>Injections intradermiques</term>
<term>Jeune adulte</term>
<term>Lymphographie</term>
<term>Membre inférieur</term>
<term>Mâle</term>
<term>Mépivacaïne</term>
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<front>
<div type="abstract" xml:lang="en">To assess for the first time the morphology of the lymphatic system in patients with lipedema and lipo-lymphedema of the lower extremities by MR lymphangiography.</div>
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<pubmed>
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<PMID Version="1">19323976</PMID>
<DateCreated>
<Year>2009</Year>
<Month>04</Month>
<Day>13</Day>
</DateCreated>
<DateCompleted>
<Year>2009</Year>
<Month>07</Month>
<Day>02</Day>
</DateCompleted>
<DateRevised>
<Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
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<Journal>
<ISSN IssnType="Electronic">1095-9319</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>77</Volume>
<Issue>3</Issue>
<PubDate>
<Year>2009</Year>
<Month>May</Month>
</PubDate>
</JournalIssue>
<Title>Microvascular research</Title>
<ISOAbbreviation>Microvasc. Res.</ISOAbbreviation>
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<ArticleTitle>MR imaging of the lymphatic system in patients with lipedema and lipo-lymphedema.</ArticleTitle>
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<MedlinePgn>335-9</MedlinePgn>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To assess for the first time the morphology of the lymphatic system in patients with lipedema and lipo-lymphedema of the lower extremities by MR lymphangiography.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">26 lower extremities in 13 consecutive patients (5 lipedema, 8 lipo-lymphedema) were examined by MR lymphangiography. 18 mL of gadoteridol and 1 mL of mepivacainhydrochloride 1% were subdivided into 10 portions and injected intracutaneously in the forefoot. MR imaging was performed with a 1.5-T system equipped with high-performance gradients. For MR lymphangiography, a 3D-spoiled gradient-echo sequence was used. For evaluation of the lymphedema a heavily T2-weighted 3D-TSE sequence was performed.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">In all 16 lower extremities (100%) with lipo-lymphedema, high signal intensity areas in the epifascial region could be detected on the 3D-TSE sequence. In the 16 examined lower extremities with lipo-lymphedema, 8 lower legs and 3 upper legs demonstrated enlarged lymphatic vessels up to a diameter of 3 mm. In two lower legs with lipo-lymphedema, an area of dermal back-flow was seen, indicating lymphatic outflow obstruction. In the 10 examined lower extremities with clinically pure lipedema, 4 lower legs and 2 upper legs demonstrated enlarged lymphatic vessels up to a diameter of 2 mm, indicating a subclinical status of lymphedema. In all examined extremities, the inguinal lymph nodes demonstrated a contrast material enhancement in the first image acquisition 15 min after injection.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">MR lymphangiography is a safe and accurate minimal-invasive imaging modality for the evaluation of the lymphatic circulation in patients with lipedema and lipo-lymphedema of the lower extremities. If the extent of lymphatic involvement is unclear at the initial clinical examination or requires a better definition for optimal therapeutic planning, MR lymphangiography is able to identify the anatomic and physiological derangements and to establish an objective baseline.</AbstractText>
</Abstract>
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<ForeName>Christian</ForeName>
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<Affiliation>Department of Radiology, University Hospital of Freiburg, Hugstetter Strasse 55, D-79106, Freiburg i. Br., Germany. christian.lohrmann@uniklinik-freiburg.de</Affiliation>
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<ForeName>Mathias</ForeName>
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<Year>2009</Year>
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<MeshHeading>
<DescriptorName UI="D000273" MajorTopicYN="N">Adipose Tissue</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
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<MeshHeading>
<DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
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<DescriptorName UI="D004487" MajorTopicYN="N">Edema</DescriptorName>
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<DescriptorName UI="D008208" MajorTopicYN="N">Lymphatic System</DescriptorName>
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<DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName>
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