LymphedemaV1, Ncbi, Merge, bibRecord, 002946

Neonatal tolerance and patent filarial infection.

Identifieur interne : 002946 ( Ncbi/Merge ); précédent : 002945; suivant : 002947

Neonatal tolerance and patent filarial infection.

Auteurs : T V Rajan [États-Unis]

Source :

Trends in parasitology [ 1471-4922 ] ; 2007.

RBID : pubmed:17888736

Descripteurs français

KwdFr :
- Animaux, Brugia malayi (immunologie), Femelle, Filariose lymphatique (immunologie), Filariose lymphatique (parasitologie), Filariose lymphatique (épidémiologie), Humains, Iles du Pacifique (épidémiologie), Indonésie (épidémiologie), Interactions hôte-parasite, Maladies endémiques, Microfilaria (immunologie), Microfilaria (parasitologie), Mâle, Tolérance immunitaire, Wuchereria bancrofti (immunologie).
MESH :
- immunologie : Brugia malayi, Filariose lymphatique, Microfilaria, Wuchereria bancrofti.
- parasitologie : Filariose lymphatique, Microfilaria.
- épidémiologie : Filariose lymphatique, Iles du Pacifique, Indonésie.
- Animaux, Femelle, Humains, Interactions hôte-parasite, Maladies endémiques, Mâle, Tolérance immunitaire.

English descriptors

KwdEn :
- Animals, Brugia malayi (immunology), Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (immunology), Elephantiasis, Filarial (parasitology), Endemic Diseases, Female, Host-Parasite Interactions, Humans, Immune Tolerance, Indonesia (epidemiology), Male, Microfilariae (immunology), Microfilariae (parasitology), Pacific Islands (epidemiology), Wuchereria bancrofti (immunology).
MESH :
- epidemiology : Elephantiasis, Filarial, Indonesia, Pacific Islands.
- immunology : Brugia malayi, Elephantiasis, Filarial, Microfilariae, Wuchereria bancrofti.
- parasitology : Elephantiasis, Filarial, Microfilariae.
- Animals, Endemic Diseases, Female, Host-Parasite Interactions, Humans, Immune Tolerance, Male.

Abstract

Lymphatic filariasis occurs in endemic pockets. Patent infections with long-term, high-grade microfilaremia do not develop in nonendemic individuals. It is tempting to speculate that individuals with intact immune responses to filarial antigens are capable of dealing with filarial exposure without developing persistent infection. There are published data that support the idea that only those individuals who are impaired in their immune defense against these parasites owing to neonatal tolerization become productively infected with the filarial parasites. If the model is correct, there are profound implications for global eradication.

DOI: 10.1016/j.pt.2007.08.009
PubMed: 17888736

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Lymphatic filariasis occurs in endemic pockets. Patent infections with long-term, high-grade microfilaremia do not develop in nonendemic individuals. It is tempting to speculate that individuals with intact immune responses to filarial antigens are capable of dealing with filarial exposure without developing persistent infection. There are published data that support the idea that only those individuals who are impaired in their immune defense against these parasites owing to neonatal tolerization become productively infected with the filarial parasites. If the model is correct, there are profound implications for global eradication.</div>
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Neonatal tolerance and patent filarial infection.

Neonatal tolerance and patent filarial infection.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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