Intensity and efficiency of transmission and the development of microfilaraemia and disease: their relationship in lymphatic filariasis.
Identifieur interne : 002651 ( Ncbi/Merge ); précédent : 002650; suivant : 002652Intensity and efficiency of transmission and the development of microfilaraemia and disease: their relationship in lymphatic filariasis.
Auteurs : B A Southgate [Royaume-Uni]Source :
- The Journal of tropical medicine and hygiene [ 0022-5304 ] ; 1992.
Descripteurs français
- KwdFr :
- MESH :
- parasitologie : Filariose lymphatique.
- sang : Filariose lymphatique.
- épidémiologie : Filariose lymphatique, Filarioses.
- Animaux, Humains, Incidence, Microfilaria, Prévalence.
English descriptors
- KwdEn :
- MESH :
- blood : Elephantiasis, Filarial.
- epidemiology : Elephantiasis, Filarial, Filariasis.
- parasitology : Elephantiasis, Filarial.
- transmission : Elephantiasis, Filarial, Filariasis.
- Animals, Humans, Incidence, Microfilariae, Prevalence.
Abstract
Currently available methods for measuring the intensity of transmission in the lymphatic filariases are all to some extent unsatisfactory. Clinical methods for defining the presence of filarial disease are also less than perfect, and many infected persons remain free of symptoms and signs for very long periods. Incidence rates of microfilaraemia calculated from prevalence rate data are combined with 'entomological inoculation rates' obtained by direct observations of vector landing rates, infective larval rates and infective larval densities in field studies to determine efficiencies of transmission, and to relate transmission parameters to observed microfilarial and disease prevalence rates. Published studies from various endemic areas of the world which provide sufficient data have been analysed, using reversible catalytic models. In general, it seems that much less intense levels of transmission are needed in sub-Saharan Africa to produce given rates of microfilaraemia and disease than in Asia and Oceania, in the case of Wuchereria bancrofti infections; similarly, the genus Anopheles appears to produce infection and disease much more efficiently than the genera Culex and Aedes when transmitting W. bancrofti. The only example of Brugia malayi transmitted by Mansonia spp. analysed provided the highest level of transmission efficiency found. Tolerable levels of transmission analogous to those used in onchocerciasis cannot at present be defined for the lymphatic filariases; it seems that the intensity of transmission required to produce new cases of disease is probably below that required to produce new cases or episodes of readily detectable microfilaraemia.
PubMed: 1740813
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 005980
- to stream PubMed, to step Curation: 005980
- to stream PubMed, to step Checkpoint: 005980
Links to Exploration step
pubmed:1740813Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Intensity and efficiency of transmission and the development of microfilaraemia and disease: their relationship in lymphatic filariasis.</title><author><name sortKey="Southgate, B A" sort="Southgate, B A" uniqKey="Southgate B" first="B A" last="Southgate">B A Southgate</name><affiliation wicri:level="1"><nlm:affiliation>London School of Hygiene and Tropical Medicine, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>London School of Hygiene and Tropical Medicine</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1992">1992</date><idno type="RBID">pubmed:1740813</idno><idno type="pmid">1740813</idno><idno type="wicri:Area/PubMed/Corpus">005980</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">005980</idno><idno type="wicri:Area/PubMed/Curation">005980</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">005980</idno><idno type="wicri:Area/PubMed/Checkpoint">005980</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">005980</idno><idno type="wicri:Area/Ncbi/Merge">002651</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Intensity and efficiency of transmission and the development of microfilaraemia and disease: their relationship in lymphatic filariasis.</title><author><name sortKey="Southgate, B A" sort="Southgate, B A" uniqKey="Southgate B" first="B A" last="Southgate">B A Southgate</name><affiliation wicri:level="1"><nlm:affiliation>London School of Hygiene and Tropical Medicine, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>London School of Hygiene and Tropical Medicine</wicri:regionArea></affiliation></author></analytic><series><title level="j">The Journal of tropical medicine and hygiene</title><idno type="ISSN">0022-5304</idno><imprint><date when="1992" type="published">1992</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Elephantiasis, Filarial (blood)</term><term>Elephantiasis, Filarial (epidemiology)</term><term>Elephantiasis, Filarial (parasitology)</term><term>Elephantiasis, Filarial (transmission)</term><term>Filariasis (epidemiology)</term><term>Filariasis (transmission)</term><term>Humans</term><term>Incidence</term><term>Microfilariae</term><term>Prevalence</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Filariose lymphatique (parasitologie)</term><term>Filariose lymphatique (sang)</term><term>Filariose lymphatique (transmission)</term><term>Filariose lymphatique (épidémiologie)</term><term>Filarioses (transmission)</term><term>Filarioses (épidémiologie)</term><term>Humains</term><term>Incidence</term><term>Microfilaria</term><term>Prévalence</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Filariasis</term></keywords><keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Filariose lymphatique</term></keywords><keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Filariose lymphatique</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Filariasis</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Filariose lymphatique</term><term>Filarioses</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Humans</term><term>Incidence</term><term>Microfilariae</term><term>Prevalence</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Humains</term><term>Incidence</term><term>Microfilaria</term><term>Prévalence</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Currently available methods for measuring the intensity of transmission in the lymphatic filariases are all to some extent unsatisfactory. Clinical methods for defining the presence of filarial disease are also less than perfect, and many infected persons remain free of symptoms and signs for very long periods. Incidence rates of microfilaraemia calculated from prevalence rate data are combined with 'entomological inoculation rates' obtained by direct observations of vector landing rates, infective larval rates and infective larval densities in field studies to determine efficiencies of transmission, and to relate transmission parameters to observed microfilarial and disease prevalence rates. Published studies from various endemic areas of the world which provide sufficient data have been analysed, using reversible catalytic models. In general, it seems that much less intense levels of transmission are needed in sub-Saharan Africa to produce given rates of microfilaraemia and disease than in Asia and Oceania, in the case of Wuchereria bancrofti infections; similarly, the genus Anopheles appears to produce infection and disease much more efficiently than the genera Culex and Aedes when transmitting W. bancrofti. The only example of Brugia malayi transmitted by Mansonia spp. analysed provided the highest level of transmission efficiency found. Tolerable levels of transmission analogous to those used in onchocerciasis cannot at present be defined for the lymphatic filariases; it seems that the intensity of transmission required to produce new cases of disease is probably below that required to produce new cases or episodes of readily detectable microfilaraemia.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">1740813</PMID><DateCreated><Year>1992</Year><Month>03</Month><Day>26</Day></DateCreated><DateCompleted><Year>1992</Year><Month>03</Month><Day>26</Day></DateCompleted><DateRevised><Year>2016</Year><Month>11</Month><Day>23</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0022-5304</ISSN><JournalIssue CitedMedium="Print"><Volume>95</Volume><Issue>1</Issue><PubDate><Year>1992</Year><Month>Feb</Month></PubDate></JournalIssue><Title>The Journal of tropical medicine and hygiene</Title><ISOAbbreviation>J Trop Med Hyg</ISOAbbreviation></Journal><ArticleTitle>Intensity and efficiency of transmission and the development of microfilaraemia and disease: their relationship in lymphatic filariasis.</ArticleTitle><Pagination><MedlinePgn>1-12</MedlinePgn></Pagination><Abstract><AbstractText>Currently available methods for measuring the intensity of transmission in the lymphatic filariases are all to some extent unsatisfactory. Clinical methods for defining the presence of filarial disease are also less than perfect, and many infected persons remain free of symptoms and signs for very long periods. Incidence rates of microfilaraemia calculated from prevalence rate data are combined with 'entomological inoculation rates' obtained by direct observations of vector landing rates, infective larval rates and infective larval densities in field studies to determine efficiencies of transmission, and to relate transmission parameters to observed microfilarial and disease prevalence rates. Published studies from various endemic areas of the world which provide sufficient data have been analysed, using reversible catalytic models. In general, it seems that much less intense levels of transmission are needed in sub-Saharan Africa to produce given rates of microfilaraemia and disease than in Asia and Oceania, in the case of Wuchereria bancrofti infections; similarly, the genus Anopheles appears to produce infection and disease much more efficiently than the genera Culex and Aedes when transmitting W. bancrofti. The only example of Brugia malayi transmitted by Mansonia spp. analysed provided the highest level of transmission efficiency found. Tolerable levels of transmission analogous to those used in onchocerciasis cannot at present be defined for the lymphatic filariases; it seems that the intensity of transmission required to produce new cases of disease is probably below that required to produce new cases or episodes of readily detectable microfilaraemia.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Southgate</LastName><ForeName>B A</ForeName><Initials>BA</Initials><AffiliationInfo><Affiliation>London School of Hygiene and Tropical Medicine, UK.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Trop Med Hyg</MedlineTA><NlmUniqueID>0406044</NlmUniqueID><ISSNLinking>0022-5304</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000469" MajorTopicYN="N">parasitology</QualifierName><QualifierName UI="Q000635" MajorTopicYN="Y">transmission</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005368" MajorTopicYN="N">Filariasis</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000635" MajorTopicYN="Y">transmission</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015994" MajorTopicYN="N">Incidence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008842" MajorTopicYN="N">Microfilariae</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading></MeshHeadingList><NumberOfReferences>88</NumberOfReferences></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1992</Year><Month>2</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1992</Year><Month>2</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1992</Year><Month>2</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">1740813</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Royaume-Uni</li></country></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Southgate, B A" sort="Southgate, B A" uniqKey="Southgate B" first="B A" last="Southgate">B A Southgate</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002651 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 002651 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= pubmed:1740813
|texte= Intensity and efficiency of transmission and the development of microfilaraemia and disease: their relationship in lymphatic filariasis.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:1740813" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |