Molecular and cellular mechanisms of lymphangiogenesis.
Identifieur interne : 001D15 ( Ncbi/Merge ); précédent : 001D14; suivant : 001D16Molecular and cellular mechanisms of lymphangiogenesis.
Auteurs : M A A. Al-Rawi [Royaume-Uni] ; R E Mansel ; W G JiangSource :
- European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology [ 0748-7983 ] ; 2005.
Descripteurs français
- KwdFr :
- Cellules endothéliales (cytologie), Cellules endothéliales (métabolisme), Endothélium lymphatique (cytologie), Endothélium lymphatique (métabolisme), Glycoprotéines (métabolisme), Glycoprotéines membranaires (métabolisme), Humains, Lymphangiogenèse (physiologie), Marqueurs biologiques (métabolisme), Protéines du transport vésiculaire, Protéines suppresseurs de tumeurs, Protéines à homéodomaine (métabolisme), Récepteur facteur croissance (métabolisme).
- MESH :
- cytologie : Cellules endothéliales, Endothélium lymphatique.
- métabolisme : Cellules endothéliales, Endothélium lymphatique, Glycoprotéines, Glycoprotéines membranaires, Marqueurs biologiques, Protéines à homéodomaine, Récepteur facteur croissance.
- physiologie : Lymphangiogenèse.
- Humains, Protéines du transport vésiculaire, Protéines suppresseurs de tumeurs.
English descriptors
- KwdEn :
- Biomarkers (metabolism), Endothelial Cells (cytology), Endothelial Cells (metabolism), Endothelium, Lymphatic (cytology), Endothelium, Lymphatic (metabolism), Glycoproteins (metabolism), Homeodomain Proteins (metabolism), Humans, Lymphangiogenesis (physiology), Membrane Glycoproteins (metabolism), Receptors, Growth Factor (metabolism), Tumor Suppressor Proteins, Vesicular Transport Proteins.
- MESH :
- chemical , metabolism : Biomarkers, Glycoproteins, Homeodomain Proteins, Membrane Glycoproteins, Receptors, Growth Factor.
- cytology : Endothelial Cells, Endothelium, Lymphatic.
- metabolism : Endothelial Cells, Endothelium, Lymphatic.
- physiology : Lymphangiogenesis.
- Humans, Tumor Suppressor Proteins, Vesicular Transport Proteins.
Abstract
Lymphangiogenesis is the growth and formation of new lymphatic vessels. It occurs in normally developing tissues and in pathological processes like inflammation, wound healing, lymphoedema and in cancer. New molecular markers that are specific to the lymphatic endothelium include: podoplanin, prox-1 and LYVE-1. The molecular mechanisms of lymphangiogenesis are not clear, but vascular endothelial growth factors (VEGF-C and VEGF-D) within tumours may simulate endothelial cells within tumour tissues to grow and generate new lymphatics. We report the current knowledge of molecular and cellular mechanisms of lymphangiogenesis.
DOI: 10.1016/j.ejso.2004.08.015
PubMed: 15698725
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pubmed:15698725Le document en format XML
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<author><name sortKey="Mansel, R E" sort="Mansel, R E" uniqKey="Mansel R" first="R E" last="Mansel">R E Mansel</name>
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<term>Endothelium, Lymphatic (metabolism)</term>
<term>Glycoproteins (metabolism)</term>
<term>Homeodomain Proteins (metabolism)</term>
<term>Humans</term>
<term>Lymphangiogenesis (physiology)</term>
<term>Membrane Glycoproteins (metabolism)</term>
<term>Receptors, Growth Factor (metabolism)</term>
<term>Tumor Suppressor Proteins</term>
<term>Vesicular Transport Proteins</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Cellules endothéliales (cytologie)</term>
<term>Cellules endothéliales (métabolisme)</term>
<term>Endothélium lymphatique (cytologie)</term>
<term>Endothélium lymphatique (métabolisme)</term>
<term>Glycoprotéines (métabolisme)</term>
<term>Glycoprotéines membranaires (métabolisme)</term>
<term>Humains</term>
<term>Lymphangiogenèse (physiologie)</term>
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<term>Protéines suppresseurs de tumeurs</term>
<term>Protéines à homéodomaine (métabolisme)</term>
<term>Récepteur facteur croissance (métabolisme)</term>
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<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Biomarkers</term>
<term>Glycoproteins</term>
<term>Homeodomain Proteins</term>
<term>Membrane Glycoproteins</term>
<term>Receptors, Growth Factor</term>
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<keywords scheme="MESH" qualifier="cytologie" xml:lang="fr"><term>Cellules endothéliales</term>
<term>Endothélium lymphatique</term>
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<term>Marqueurs biologiques</term>
<term>Protéines à homéodomaine</term>
<term>Récepteur facteur croissance</term>
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<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Lymphangiogenèse</term>
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<term>Tumor Suppressor Proteins</term>
<term>Vesicular Transport Proteins</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Humains</term>
<term>Protéines du transport vésiculaire</term>
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<front><div type="abstract" xml:lang="en">Lymphangiogenesis is the growth and formation of new lymphatic vessels. It occurs in normally developing tissues and in pathological processes like inflammation, wound healing, lymphoedema and in cancer. New molecular markers that are specific to the lymphatic endothelium include: podoplanin, prox-1 and LYVE-1. The molecular mechanisms of lymphangiogenesis are not clear, but vascular endothelial growth factors (VEGF-C and VEGF-D) within tumours may simulate endothelial cells within tumour tissues to grow and generate new lymphatics. We report the current knowledge of molecular and cellular mechanisms of lymphangiogenesis.</div>
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<Abstract><AbstractText>Lymphangiogenesis is the growth and formation of new lymphatic vessels. It occurs in normally developing tissues and in pathological processes like inflammation, wound healing, lymphoedema and in cancer. New molecular markers that are specific to the lymphatic endothelium include: podoplanin, prox-1 and LYVE-1. The molecular mechanisms of lymphangiogenesis are not clear, but vascular endothelial growth factors (VEGF-C and VEGF-D) within tumours may simulate endothelial cells within tumour tissues to grow and generate new lymphatics. We report the current knowledge of molecular and cellular mechanisms of lymphangiogenesis.</AbstractText>
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