Influence of infection with non-filarial helminths on the specificity of serological assays for antifilarial immunoglobulin G4.
Identifieur interne : 000E22 ( Ncbi/Merge ); précédent : 000E21; suivant : 000E23Influence of infection with non-filarial helminths on the specificity of serological assays for antifilarial immunoglobulin G4.
Auteurs : A E Muck [États-Unis] ; M L Pires ; P J LammieSource :
- Transactions of the Royal Society of Tropical Medicine and Hygiene [ 0035-9203 ]
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Anticorps antihelminthe (sang), Antigènes d'helminthe (sang), Brésil (épidémiologie), Enfant, Filariose lymphatique (diagnostic), Filariose lymphatique (immunologie), Filariose lymphatique (épidémiologie), Humains, Immunoglobuline G (sang), Sensibilité et spécificité, Strongyloides (immunologie), Strongyloïdose (diagnostic), Strongyloïdose (immunologie), Strongyloïdose (épidémiologie), Sujet âgé, Test ELISA (), Tests sérologiques (), Tests sérologiques (normes), Wuchereria bancrofti (immunologie).
- MESH :
- diagnostic : Filariose lymphatique, Strongyloïdose.
- immunologie : Filariose lymphatique, Strongyloides, Strongyloïdose, Wuchereria bancrofti.
- normes : Tests sérologiques.
- sang : Anticorps antihelminthe, Antigènes d'helminthe, Immunoglobuline G.
- épidémiologie : Brésil, Filariose lymphatique, Strongyloïdose.
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Enfant, Humains, Sensibilité et spécificité, Sujet âgé, Test ELISA, Tests sérologiques.
- Wicri :
- geographic : Brésil.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Animals, Antibodies, Helminth (blood), Antigens, Helminth (blood), Brazil (epidemiology), Child, Elephantiasis, Filarial (diagnosis), Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (immunology), Enzyme-Linked Immunosorbent Assay (methods), Humans, Immunoglobulin G (blood), Middle Aged, Sensitivity and Specificity, Serologic Tests (methods), Serologic Tests (standards), Strongyloides (immunology), Strongyloidiasis (diagnosis), Strongyloidiasis (epidemiology), Strongyloidiasis (immunology), Wuchereria bancrofti (immunology).
- MESH :
- chemical , blood : Antibodies, Helminth, Antigens, Helminth, Immunoglobulin G.
- geographic , epidemiology : Brazil.
- diagnosis : Elephantiasis, Filarial, Strongyloidiasis.
- epidemiology : Elephantiasis, Filarial, Strongyloidiasis.
- immunology : Elephantiasis, Filarial, Strongyloides, Strongyloidiasis, Wuchereria bancrofti.
- methods : Enzyme-Linked Immunosorbent Assay, Serologic Tests.
- standards : Serologic Tests.
- Adolescent, Adult, Aged, Animals, Child, Humans, Middle Aged, Sensitivity and Specificity.
Abstract
Serological assays based on the detection of immunoglobulin (Ig) G4 antibodies to crude filarial extracts are widely used for epidemiological and diagnostic purposes. We tested 195 samples collected in 1998 from an area of Brazil where filariasis is not endemic and 13 (6.7%) had levels of antifilarial IgG4 antibodies that were defined as positive. Both Strongyloides infection and the presence of Strongyloides antibody responses were associated with higher antifilarial antibody responses. None of the specimens had a positive response to the Brugia malayi recombinant antigen (Bm14). These data suggest that serodiagnostic assays based on the use of crude filarial antigens should be interpreted with caution because of the potential for cross-reactivity with Strongyloides.
PubMed: 12886811
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 004213
- to stream PubMed, to step Curation: 004213
- to stream PubMed, to step Checkpoint: 004213
Links to Exploration step
pubmed:12886811Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Influence of infection with non-filarial helminths on the specificity of serological assays for antifilarial immunoglobulin G4.</title><author><name sortKey="Muck, A E" sort="Muck, A E" uniqKey="Muck A" first="A E" last="Muck">A E Muck</name><affiliation wicri:level="2"><nlm:affiliation>Division of Parasitic Diseases/F13, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA 30341, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Parasitic Diseases/F13, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA 30341</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Pires, M L" sort="Pires, M L" uniqKey="Pires M" first="M L" last="Pires">M L Pires</name></author><author><name sortKey="Lammie, P J" sort="Lammie, P J" uniqKey="Lammie P" first="P J" last="Lammie">P J Lammie</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="????"><PubDate><MedlineDate>2003 Jan-Feb</MedlineDate></PubDate></date><idno type="RBID">pubmed:12886811</idno><idno type="pmid">12886811</idno><idno type="wicri:Area/PubMed/Corpus">004213</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">004213</idno><idno type="wicri:Area/PubMed/Curation">004213</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">004213</idno><idno type="wicri:Area/PubMed/Checkpoint">004213</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">004213</idno><idno type="wicri:Area/Ncbi/Merge">000E22</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Influence of infection with non-filarial helminths on the specificity of serological assays for antifilarial immunoglobulin G4.</title><author><name sortKey="Muck, A E" sort="Muck, A E" uniqKey="Muck A" first="A E" last="Muck">A E Muck</name><affiliation wicri:level="2"><nlm:affiliation>Division of Parasitic Diseases/F13, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA 30341, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Parasitic Diseases/F13, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA 30341</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Pires, M L" sort="Pires, M L" uniqKey="Pires M" first="M L" last="Pires">M L Pires</name></author><author><name sortKey="Lammie, P J" sort="Lammie, P J" uniqKey="Lammie P" first="P J" last="Lammie">P J Lammie</name></author></analytic><series><title level="j">Transactions of the Royal Society of Tropical Medicine and Hygiene</title><idno type="ISSN">0035-9203</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Animals</term><term>Antibodies, Helminth (blood)</term><term>Antigens, Helminth (blood)</term><term>Brazil (epidemiology)</term><term>Child</term><term>Elephantiasis, Filarial (diagnosis)</term><term>Elephantiasis, Filarial (epidemiology)</term><term>Elephantiasis, Filarial (immunology)</term><term>Enzyme-Linked Immunosorbent Assay (methods)</term><term>Humans</term><term>Immunoglobulin G (blood)</term><term>Middle Aged</term><term>Sensitivity and Specificity</term><term>Serologic Tests (methods)</term><term>Serologic Tests (standards)</term><term>Strongyloides (immunology)</term><term>Strongyloidiasis (diagnosis)</term><term>Strongyloidiasis (epidemiology)</term><term>Strongyloidiasis (immunology)</term><term>Wuchereria bancrofti (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Animaux</term><term>Anticorps antihelminthe (sang)</term><term>Antigènes d'helminthe (sang)</term><term>Brésil (épidémiologie)</term><term>Enfant</term><term>Filariose lymphatique (diagnostic)</term><term>Filariose lymphatique (immunologie)</term><term>Filariose lymphatique (épidémiologie)</term><term>Humains</term><term>Immunoglobuline G (sang)</term><term>Sensibilité et spécificité</term><term>Strongyloides (immunologie)</term><term>Strongyloïdose (diagnostic)</term><term>Strongyloïdose (immunologie)</term><term>Strongyloïdose (épidémiologie)</term><term>Sujet âgé</term><term>Test ELISA ()</term><term>Tests sérologiques ()</term><term>Tests sérologiques (normes)</term><term>Wuchereria bancrofti (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Helminth</term><term>Antigens, Helminth</term><term>Immunoglobulin G</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Brazil</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Strongyloidiasis</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Filariose lymphatique</term><term>Strongyloïdose</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Strongyloidiasis</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Filariose lymphatique</term><term>Strongyloides</term><term>Strongyloïdose</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Strongyloides</term><term>Strongyloidiasis</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Enzyme-Linked Immunosorbent Assay</term><term>Serologic Tests</term></keywords><keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Tests sérologiques</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antihelminthe</term><term>Antigènes d'helminthe</term><term>Immunoglobuline G</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Serologic Tests</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Brésil</term><term>Filariose lymphatique</term><term>Strongyloïdose</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Animals</term><term>Child</term><term>Humans</term><term>Middle Aged</term><term>Sensitivity and Specificity</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Animaux</term><term>Enfant</term><term>Humains</term><term>Sensibilité et spécificité</term><term>Sujet âgé</term><term>Test ELISA</term><term>Tests sérologiques</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Brésil</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Serological assays based on the detection of immunoglobulin (Ig) G4 antibodies to crude filarial extracts are widely used for epidemiological and diagnostic purposes. We tested 195 samples collected in 1998 from an area of Brazil where filariasis is not endemic and 13 (6.7%) had levels of antifilarial IgG4 antibodies that were defined as positive. Both Strongyloides infection and the presence of Strongyloides antibody responses were associated with higher antifilarial antibody responses. None of the specimens had a positive response to the Brugia malayi recombinant antigen (Bm14). These data suggest that serodiagnostic assays based on the use of crude filarial antigens should be interpreted with caution because of the potential for cross-reactivity with Strongyloides.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12886811</PMID><DateCreated><Year>2003</Year><Month>07</Month><Day>30</Day></DateCreated><DateCompleted><Year>2003</Year><Month>09</Month><Day>02</Day></DateCompleted><DateRevised><Year>2004</Year><Month>11</Month><Day>17</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0035-9203</ISSN><JournalIssue CitedMedium="Print"><Volume>97</Volume><Issue>1</Issue><PubDate><MedlineDate>2003 Jan-Feb</MedlineDate></PubDate></JournalIssue><Title>Transactions of the Royal Society of Tropical Medicine and Hygiene</Title><ISOAbbreviation>Trans. R. Soc. Trop. Med. Hyg.</ISOAbbreviation></Journal><ArticleTitle>Influence of infection with non-filarial helminths on the specificity of serological assays for antifilarial immunoglobulin G4.</ArticleTitle><Pagination><MedlinePgn>88-90</MedlinePgn></Pagination><Abstract><AbstractText>Serological assays based on the detection of immunoglobulin (Ig) G4 antibodies to crude filarial extracts are widely used for epidemiological and diagnostic purposes. We tested 195 samples collected in 1998 from an area of Brazil where filariasis is not endemic and 13 (6.7%) had levels of antifilarial IgG4 antibodies that were defined as positive. Both Strongyloides infection and the presence of Strongyloides antibody responses were associated with higher antifilarial antibody responses. None of the specimens had a positive response to the Brugia malayi recombinant antigen (Bm14). These data suggest that serodiagnostic assays based on the use of crude filarial antigens should be interpreted with caution because of the potential for cross-reactivity with Strongyloides.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Muck</LastName><ForeName>A E</ForeName><Initials>AE</Initials><AffiliationInfo><Affiliation>Division of Parasitic Diseases/F13, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA 30341, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pires</LastName><ForeName>M L</ForeName><Initials>ML</Initials></Author><Author ValidYN="Y"><LastName>Lammie</LastName><ForeName>P J</ForeName><Initials>PJ</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Trans R Soc Trop Med Hyg</MedlineTA><NlmUniqueID>7506129</NlmUniqueID><ISSNLinking>0035-9203</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000909">Antibodies, Helminth</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000947">Antigens, Helminth</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007074">Immunoglobulin G</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000909" MajorTopicYN="N">Antibodies, Helminth</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000947" MajorTopicYN="N">Antigens, Helminth</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001938" MajorTopicYN="N" Type="Geographic">Brazil</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004797" MajorTopicYN="N">Enzyme-Linked Immunosorbent Assay</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007074" MajorTopicYN="N">Immunoglobulin G</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012680" MajorTopicYN="N">Sensitivity and Specificity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012698" MajorTopicYN="N">Serologic Tests</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName><QualifierName UI="Q000592" MajorTopicYN="N">standards</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013321" MajorTopicYN="N">Strongyloides</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013322" MajorTopicYN="N">Strongyloidiasis</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014958" MajorTopicYN="N">Wuchereria bancrofti</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year><Month>7</Month><Day>31</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2003</Year><Month>9</Month><Day>3</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2003</Year><Month>7</Month><Day>31</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">12886811</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Géorgie (États-Unis)</li></region></list><tree><noCountry><name sortKey="Lammie, P J" sort="Lammie, P J" uniqKey="Lammie P" first="P J" last="Lammie">P J Lammie</name><name sortKey="Pires, M L" sort="Pires, M L" uniqKey="Pires M" first="M L" last="Pires">M L Pires</name></noCountry><country name="États-Unis"><region name="Géorgie (États-Unis)"><name sortKey="Muck, A E" sort="Muck, A E" uniqKey="Muck A" first="A E" last="Muck">A E Muck</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E22 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 000E22 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= pubmed:12886811
|texte= Influence of infection with non-filarial helminths on the specificity of serological assays for antifilarial immunoglobulin G4.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:12886811" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |