Quantitative radionuclide lymphoscintigraphy predicts outcome of manual lymphatic therapy in breast cancer-related lymphedema of the upper extremity.
Identifieur interne : 000B73 ( Ncbi/Merge ); précédent : 000B72; suivant : 000B74Quantitative radionuclide lymphoscintigraphy predicts outcome of manual lymphatic therapy in breast cancer-related lymphedema of the upper extremity.
Auteurs : A. Szuba [États-Unis] ; W. Strauss ; S P Sirsikar ; S G RocksonSource :
- Nuclear medicine communications [ 0143-3636 ] ; 2002.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Complications postopératoires (), Complications postopératoires (imagerie diagnostique), Femelle, Humains, Lymphoedème (), Lymphoedème (imagerie diagnostique), Lymphoedème (étiologie), Lymphoscintigraphie, Mastectomie, Membre supérieur (anatomopathologie), Noeuds lymphatiques (imagerie diagnostique), Radiopharmaceutiques, Sujet âgé, Sulfocolloïde de technétium (99mTc), Techniques de physiothérapie, Tumeurs du sein (), Valeur prédictive des tests.
- MESH :
- anatomopathologie : Membre supérieur.
- imagerie diagnostique : Complications postopératoires, Lymphoedème, Noeuds lymphatiques.
- étiologie : Lymphoedème.
- Adulte d'âge moyen, Complications postopératoires, Femelle, Humains, Lymphoedème, Lymphoscintigraphie, Mastectomie, Radiopharmaceutiques, Sujet âgé, Sulfocolloïde de technétium (99mTc), Techniques de physiothérapie, Tumeurs du sein, Valeur prédictive des tests.
English descriptors
- KwdEn :
- Aged, Breast Neoplasms (complications), Female, Humans, Lymph Nodes (diagnostic imaging), Lymphedema (diagnostic imaging), Lymphedema (etiology), Lymphedema (therapy), Lymphoscintigraphy, Mastectomy, Middle Aged, Physical Therapy Modalities, Postoperative Complications (diagnostic imaging), Postoperative Complications (therapy), Predictive Value of Tests, Radiopharmaceuticals, Technetium Tc 99m Sulfur Colloid, Upper Extremity (pathology).
- MESH :
- chemical : Radiopharmaceuticals, Technetium Tc 99m Sulfur Colloid.
- complications : Breast Neoplasms.
- diagnostic imaging : Lymph Nodes, Lymphedema, Postoperative Complications.
- etiology : Lymphedema.
- pathology : Upper Extremity.
- therapy : Lymphedema, Postoperative Complications.
- Aged, Female, Humans, Lymphoscintigraphy, Mastectomy, Middle Aged, Physical Therapy Modalities, Predictive Value of Tests.
Abstract
Secondary lymphedema is a localized, acquired lymphatic microcirculatory disturbance that affects large numbers of patients after breast cancer therapy. There is a paucity of objective methods to quantitate lymphatic function and to anticipate the response to therapeutic interventions. We applied radionuclide lymphoscintigraphy to evaluate lymphatic transport and axillary lymph node visualization in women following breast cancer therapy to determine the utility of these data in these patients. Lymphoscintigraphy was performed after subcutaneous injection of 0.25 mCi of Tc-filtered sulfur colloid. Subcutaneous accumulation of radiotracer ('dermal backflow') and the visualization of axillary lymph nodes were graded using our own scoring system. The ratio of radioactivity within the affected to normal axillae (ARR) was also quantified. Nineteen patients with lymphedema after breast cancer therapy were evaluated. The disease severity was documented by serial measurements of the limb volume using the truncated cone formula. Responses to therapy were quantified after completion of the therapy. There was a correlation between the ARR and the percentage reduction in edema volume. The lymphoscintigraphic score correlated with the initial arm volume excess and with the durationof lymphedema. It can be concluded that quantitative and semi-quantitative assessment by radionuclide lymphoscintigraphy represents a potentially useful tool for the clinical assessment of upper extremity lymphedema.
DOI: 10.1097/01.mnm.0000046208.83338.da
PubMed: 12464781
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Szuba</name><affiliation wicri:level="2"><nlm:affiliation>Stanford Center for Lymphatic and Venous Disorders, Division of Cardiovascular Medicine and Division of Nuclear Medicine, Stanford University School of Medicine, Stanford, CA 94306, USA. aszuba@cvmed.stanford.edu</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stanford Center for Lymphatic and Venous Disorders, Division of Cardiovascular Medicine and Division of Nuclear Medicine, Stanford University School of Medicine, Stanford, CA 94306</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Strauss, W" sort="Strauss, W" uniqKey="Strauss W" first="W" last="Strauss">W. 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There is a paucity of objective methods to quantitate lymphatic function and to anticipate the response to therapeutic interventions. We applied radionuclide lymphoscintigraphy to evaluate lymphatic transport and axillary lymph node visualization in women following breast cancer therapy to determine the utility of these data in these patients. Lymphoscintigraphy was performed after subcutaneous injection of 0.25 mCi of Tc-filtered sulfur colloid. Subcutaneous accumulation of radiotracer ('dermal backflow') and the visualization of axillary lymph nodes were graded using our own scoring system. The ratio of radioactivity within the affected to normal axillae (ARR) was also quantified. Nineteen patients with lymphedema after breast cancer therapy were evaluated. The disease severity was documented by serial measurements of the limb volume using the truncated cone formula. Responses to therapy were quantified after completion of the therapy. There was a correlation between the ARR and the percentage reduction in edema volume. The lymphoscintigraphic score correlated with the initial arm volume excess and with the durationof lymphedema. It can be concluded that quantitative and semi-quantitative assessment by radionuclide lymphoscintigraphy represents a potentially useful tool for the clinical assessment of upper extremity lymphedema.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12464781</PMID><DateCreated><Year>2002</Year><Month>12</Month><Day>04</Day></DateCreated><DateCompleted><Year>2003</Year><Month>06</Month><Day>30</Day></DateCompleted><DateRevised><Year>2016</Year><Month>11</Month><Day>24</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0143-3636</ISSN><JournalIssue CitedMedium="Print"><Volume>23</Volume><Issue>12</Issue><PubDate><Year>2002</Year><Month>Dec</Month></PubDate></JournalIssue><Title>Nuclear medicine communications</Title><ISOAbbreviation>Nucl Med Commun</ISOAbbreviation></Journal><ArticleTitle>Quantitative radionuclide lymphoscintigraphy predicts outcome of manual lymphatic therapy in breast cancer-related lymphedema of the upper extremity.</ArticleTitle><Pagination><MedlinePgn>1171-5</MedlinePgn></Pagination><Abstract><AbstractText>Secondary lymphedema is a localized, acquired lymphatic microcirculatory disturbance that affects large numbers of patients after breast cancer therapy. There is a paucity of objective methods to quantitate lymphatic function and to anticipate the response to therapeutic interventions. We applied radionuclide lymphoscintigraphy to evaluate lymphatic transport and axillary lymph node visualization in women following breast cancer therapy to determine the utility of these data in these patients. Lymphoscintigraphy was performed after subcutaneous injection of 0.25 mCi of Tc-filtered sulfur colloid. Subcutaneous accumulation of radiotracer ('dermal backflow') and the visualization of axillary lymph nodes were graded using our own scoring system. The ratio of radioactivity within the affected to normal axillae (ARR) was also quantified. Nineteen patients with lymphedema after breast cancer therapy were evaluated. The disease severity was documented by serial measurements of the limb volume using the truncated cone formula. Responses to therapy were quantified after completion of the therapy. There was a correlation between the ARR and the percentage reduction in edema volume. The lymphoscintigraphic score correlated with the initial arm volume excess and with the durationof lymphedema. It can be concluded that quantitative and semi-quantitative assessment by radionuclide lymphoscintigraphy represents a potentially useful tool for the clinical assessment of upper extremity lymphedema.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Szuba</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Stanford Center for Lymphatic and Venous Disorders, Division of Cardiovascular Medicine and Division of Nuclear Medicine, Stanford University School of Medicine, Stanford, CA 94306, USA. aszuba@cvmed.stanford.edu</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Strauss</LastName><ForeName>W</ForeName><Initials>W</Initials></Author><Author ValidYN="Y"><LastName>Sirsikar</LastName><ForeName>S P</ForeName><Initials>SP</Initials></Author><Author ValidYN="Y"><LastName>Rockson</LastName><ForeName>S 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MajorTopicYN="N">Mastectomy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D026741" MajorTopicYN="Y">Physical Therapy Modalities</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011183" MajorTopicYN="N">Postoperative Complications</DescriptorName><QualifierName UI="Q000000981" MajorTopicYN="N">diagnostic imaging</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011237" MajorTopicYN="N">Predictive Value of Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019275" MajorTopicYN="N">Radiopharmaceuticals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013671" MajorTopicYN="N">Technetium Tc 99m Sulfur Colloid</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D034941" MajorTopicYN="Y">Upper Extremity</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2002</Year><Month>12</Month><Day>5</Day><Hour>4</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2003</Year><Month>7</Month><Day>2</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2002</Year><Month>12</Month><Day>5</Day><Hour>4</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">12464781</ArticleId><ArticleId IdType="doi">10.1097/01.mnm.0000046208.83338.da</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li></region></list><tree><noCountry><name sortKey="Rockson, S G" sort="Rockson, S G" uniqKey="Rockson S" first="S G" last="Rockson">S G Rockson</name><name sortKey="Sirsikar, S P" sort="Sirsikar, S P" uniqKey="Sirsikar S" first="S P" last="Sirsikar">S P Sirsikar</name><name sortKey="Strauss, W" sort="Strauss, W" uniqKey="Strauss W" first="W" last="Strauss">W. Strauss</name></noCountry><country name="États-Unis"><region name="Californie"><name sortKey="Szuba, A" sort="Szuba, A" uniqKey="Szuba A" first="A" last="Szuba">A. Szuba</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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