Chronic lymphoedema and angiosarcoma.
Identifieur interne : 000158 ( Ncbi/Merge ); précédent : 000157; suivant : 000159Chronic lymphoedema and angiosarcoma.
Auteurs : R M Azurdia [Royaume-Uni] ; D M Guerin ; J L VerbovSource :
- Clinical and experimental dermatology [ 0307-6938 ] ; 1999.
Descripteurs français
- KwdFr :
- Humains, Issue fatale, Jambe (effets des radiations), Lymphangiosarcome (étiologie), Lymphoedème (), Lymphome malin non hodgkinien (traitement médicamenteux), Maladie chronique, Maladie de Hodgkin (radiothérapie), Mâle, Pronostic, Protocoles de polychimiothérapie antinéoplasique (usage thérapeutique), Seconde tumeur primitive (traitement médicamenteux), Seconde tumeur primitive (étiologie), Soins palliatifs, Sujet âgé, Sujet âgé de 80 ans ou plus, Tumeurs cutanées (étiologie).
- MESH :
- effets des radiations : Jambe.
- radiothérapie : Maladie de Hodgkin.
- traitement médicamenteux : Lymphome malin non hodgkinien, Seconde tumeur primitive.
- usage thérapeutique : Protocoles de polychimiothérapie antinéoplasique.
- étiologie : Lymphangiosarcome, Seconde tumeur primitive, Tumeurs cutanées.
- Humains, Issue fatale, Lymphoedème, Maladie chronique, Mâle, Pronostic, Soins palliatifs, Sujet âgé, Sujet âgé de 80 ans ou plus.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols (therapeutic use), Chronic Disease, Fatal Outcome, Hodgkin Disease (radiotherapy), Humans, Leg (radiation effects), Lymphangiosarcoma (etiology), Lymphedema (complications), Lymphoma, Non-Hodgkin (drug therapy), Male, Neoplasms, Second Primary (drug therapy), Neoplasms, Second Primary (etiology), Palliative Care, Prognosis, Skin Neoplasms (etiology).
- MESH :
- complications : Lymphedema.
- drug therapy : Lymphoma, Non-Hodgkin, Neoplasms, Second Primary.
- etiology : Lymphangiosarcoma, Neoplasms, Second Primary, Skin Neoplasms.
- radiation effects : Leg.
- radiotherapy : Hodgkin Disease.
- therapeutic use : Antineoplastic Combined Chemotherapy Protocols.
- Aged, Aged, 80 and over, Chronic Disease, Fatal Outcome, Humans, Male, Palliative Care, Prognosis.
Abstract
Angiosarcoma has frequently been described arising within chronic lymphoedema of the upper limb following mastectomy and radiotherapy for carcinoma of the breast. We report a case of angiosarcoma arising in a lymphoedematous leg that had been subjected to radiotherapy 20 years previously for Hodgkin's disease. The diagnosis was expedited once the patient noticed the development of bleeding nodules. Prognosis of angiosarcoma is poor with treatment options being wide-excision surgery, palliative radiotherapy or chemotherapy. Unusual bruised areas or bleeding nodules developing within chronic lymphoedematous limbs should be biopsied to exclude the diagnosis.
PubMed: 10457127
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pubmed:10457127Le document en format XML
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qualifier="therapeutic use" xml:lang="en"><term>Antineoplastic Combined Chemotherapy Protocols</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Lymphome malin non hodgkinien</term><term>Seconde tumeur primitive</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Protocoles de polychimiothérapie antinéoplasique</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lymphangiosarcome</term><term>Seconde tumeur primitive</term><term>Tumeurs cutanées</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Chronic Disease</term><term>Fatal Outcome</term><term>Humans</term><term>Male</term><term>Palliative Care</term><term>Prognosis</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Issue fatale</term><term>Lymphoedème</term><term>Maladie 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We report a case of angiosarcoma arising in a lymphoedematous leg that had been subjected to radiotherapy 20 years previously for Hodgkin's disease. The diagnosis was expedited once the patient noticed the development of bleeding nodules. Prognosis of angiosarcoma is poor with treatment options being wide-excision surgery, palliative radiotherapy or chemotherapy. Unusual bruised areas or bleeding nodules developing within chronic lymphoedematous limbs should be biopsied to exclude the diagnosis.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">10457127</PMID><DateCreated><Year>1999</Year><Month>09</Month><Day>10</Day></DateCreated><DateCompleted><Year>1999</Year><Month>09</Month><Day>10</Day></DateCompleted><DateRevised><Year>2006</Year><Month>04</Month><Day>24</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0307-6938</ISSN><JournalIssue CitedMedium="Print"><Volume>24</Volume><Issue>4</Issue><PubDate><Year>1999</Year><Month>Jul</Month></PubDate></JournalIssue><Title>Clinical and experimental dermatology</Title><ISOAbbreviation>Clin. Exp. Dermatol.</ISOAbbreviation></Journal><ArticleTitle>Chronic lymphoedema and angiosarcoma.</ArticleTitle><Pagination><MedlinePgn>270-2</MedlinePgn></Pagination><Abstract><AbstractText>Angiosarcoma has frequently been described arising within chronic lymphoedema of the upper limb following mastectomy and radiotherapy for carcinoma of the breast. We report a case of angiosarcoma arising in a lymphoedematous leg that had been subjected to radiotherapy 20 years previously for Hodgkin's disease. The diagnosis was expedited once the patient noticed the development of bleeding nodules. Prognosis of angiosarcoma is poor with treatment options being wide-excision surgery, palliative radiotherapy or chemotherapy. Unusual bruised areas or bleeding nodules developing within chronic lymphoedematous limbs should be biopsied to exclude the diagnosis.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Azurdia</LastName><ForeName>R M</ForeName><Initials>RM</Initials><AffiliationInfo><Affiliation>Department of Dermatology, The Royal Liverpool University Hospital NHS Trust, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guerin</LastName><ForeName>D M</ForeName><Initials>DM</Initials></Author><Author ValidYN="Y"><LastName>Verbov</LastName><ForeName>J L</ForeName><Initials>JL</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Clin Exp Dermatol</MedlineTA><NlmUniqueID>7606847</NlmUniqueID><ISSNLinking>0307-6938</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000971" MajorTopicYN="N">Antineoplastic Combined Chemotherapy Protocols</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002908" MajorTopicYN="N">Chronic Disease</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017809" MajorTopicYN="N">Fatal Outcome</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006689" MajorTopicYN="N">Hodgkin Disease</DescriptorName><QualifierName UI="Q000532" MajorTopicYN="N">radiotherapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007866" MajorTopicYN="Y">Leg</DescriptorName><QualifierName UI="Q000528" MajorTopicYN="N">radiation effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008204" MajorTopicYN="N">Lymphangiosarcoma</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008228" MajorTopicYN="N">Lymphoma, Non-Hodgkin</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016609" MajorTopicYN="N">Neoplasms, Second Primary</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010166" MajorTopicYN="N">Palliative Care</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011379" MajorTopicYN="N">Prognosis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012878" MajorTopicYN="N">Skin Neoplasms</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1999</Year><Month>8</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1999</Year><Month>8</Month><Day>24</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1999</Year><Month>8</Month><Day>24</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">10457127</ArticleId><ArticleId IdType="pii">ced476</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Royaume-Uni</li></country></list><tree><noCountry><name sortKey="Guerin, D M" sort="Guerin, D M" uniqKey="Guerin D" first="D M" last="Guerin">D M Guerin</name><name sortKey="Verbov, J L" sort="Verbov, J L" uniqKey="Verbov J" first="J L" last="Verbov">J L Verbov</name></noCountry><country name="Royaume-Uni"><noRegion><name sortKey="Azurdia, R M" sort="Azurdia, R M" uniqKey="Azurdia R" first="R M" last="Azurdia">R M Azurdia</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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