LymphedemaV1, Ncbi, Merge, bibRecord, 000155

Complications of Level I and II Axillary Dissection in the Treatment of Carcinoma of the Breast

Identifieur interne : 000155 ( Ncbi/Merge ); précédent : 000154; suivant : 000156

Complications of Level I and II Axillary Dissection in the Treatment of Carcinoma of the Breast

Auteurs : Daniel F. Roses ; Ari D. Brooks ; Matthew N. Harris ; Richard L. Shapiro ; Julie Mitnick

Source :

Annals of Surgery [ 0003-4932 ] ; 1999.

RBID : PMC:1420861

Abstract

Objective

To assess the complications of level I and II axillary lymph node dissection in the treatment of stage I and II breast cancer, with breast-conservation surgery and mastectomy.

Summary Background Data

The role of axillary dissection for staging, and as an effective means of controlling regional nodal disease, has long been recognized. As small and low-grade lesions have been detected more frequently, and as its therapeutic impact has been questioned, axillary dissection has increasingly been perceived as associated with significant complications.

Methods

Two hundred patients, 112 of whom had breast-conservation surgery with axillary dissection and 88 of whom had total mastectomy with axillary dissection, were evaluated 1 year or more after surgery for arm swelling as well as nonedema complications. All patients had arm circumference measurements at the same four sites on both the operated and nonoperated sides.

Results

No patient had an axillary recurrence. The mean difference in circumference on the nonoperated versus operated side was 0.425 cm ± 1.39 at the midbiceps (p < 0.001), 0.315 cm ± 1.27 at the antecubital fossa (p < 0.001), 0.355 cm ± 1.53 at the midforearm (p < 0.005), and 0.055 cm ± 0.75 at the wrist (n.s.). Seven patients (3.5%) had mild swelling of the hand. Heavy and obese body habitus were the only significant predictors of edema on multivariate analysis. One hundred fifty-three (76.5%) patients had numbness or paresthesias of the medial arm and/or axilla after surgery; in 125 (82%) of these, the problem had lessened or had resolved on follow-up assessment.

Conclusions

The characterization of a level I and II axillary dissection as a procedure with significant complications does not appear justified based on this experience.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420861

PubMed: 10450733
PubMed Central: 1420861

Links toward previous steps (curation, corpus...)

to stream Pmc, to step Corpus: 001344
to stream Pmc, to step Curation: 001343
to stream Pmc, to step Checkpoint: 004147

Links to Exploration step

PMC:1420861

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Complications of Level I and II Axillary Dissection in the Treatment of Carcinoma of the Breast</title>
<author><name sortKey="Roses, Daniel F" sort="Roses, Daniel F" uniqKey="Roses D" first="Daniel F." last="Roses">Daniel F. Roses</name>
<affiliation><nlm:aff id="N0x8b4ded0.0x8c6eca8"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Brooks, Ari D" sort="Brooks, Ari D" uniqKey="Brooks A" first="Ari D." last="Brooks">Ari D. Brooks</name>
<affiliation><nlm:aff id="N0x8b4ded0.0x8c6eca8"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Harris, Matthew N" sort="Harris, Matthew N" uniqKey="Harris M" first="Matthew N." last="Harris">Matthew N. Harris</name>
<affiliation><nlm:aff id="N0x8b4ded0.0x8c6eca8"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Shapiro, Richard L" sort="Shapiro, Richard L" uniqKey="Shapiro R" first="Richard L." last="Shapiro">Richard L. Shapiro</name>
<affiliation><nlm:aff id="N0x8b4ded0.0x8c6eca8"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mitnick, Julie" sort="Mitnick, Julie" uniqKey="Mitnick J" first="Julie" last="Mitnick">Julie Mitnick</name>
<affiliation><nlm:aff id="N0x8b4ded0.0x8c6eca8"></nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">10450733</idno>
<idno type="pmc">1420861</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420861</idno>
<idno type="RBID">PMC:1420861</idno>
<date when="1999">1999</date>
<idno type="wicri:Area/Pmc/Corpus">001344</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001344</idno>
<idno type="wicri:Area/Pmc/Curation">001343</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001343</idno>
<idno type="wicri:Area/Pmc/Checkpoint">004147</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">004147</idno>
<idno type="wicri:Area/Ncbi/Merge">000155</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Complications of Level I and II Axillary Dissection in the Treatment of Carcinoma of the Breast</title>
<author><name sortKey="Roses, Daniel F" sort="Roses, Daniel F" uniqKey="Roses D" first="Daniel F." last="Roses">Daniel F. Roses</name>
<affiliation><nlm:aff id="N0x8b4ded0.0x8c6eca8"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Brooks, Ari D" sort="Brooks, Ari D" uniqKey="Brooks A" first="Ari D." last="Brooks">Ari D. Brooks</name>
<affiliation><nlm:aff id="N0x8b4ded0.0x8c6eca8"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Harris, Matthew N" sort="Harris, Matthew N" uniqKey="Harris M" first="Matthew N." last="Harris">Matthew N. Harris</name>
<affiliation><nlm:aff id="N0x8b4ded0.0x8c6eca8"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Shapiro, Richard L" sort="Shapiro, Richard L" uniqKey="Shapiro R" first="Richard L." last="Shapiro">Richard L. Shapiro</name>
<affiliation><nlm:aff id="N0x8b4ded0.0x8c6eca8"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mitnick, Julie" sort="Mitnick, Julie" uniqKey="Mitnick J" first="Julie" last="Mitnick">Julie Mitnick</name>
<affiliation><nlm:aff id="N0x8b4ded0.0x8c6eca8"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Annals of Surgery</title>
<idno type="ISSN">0003-4932</idno>
<idno type="eISSN">1528-1140</idno>
<imprint><date when="1999">1999</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Objective</title>
<p>To assess the complications of level I and II axillary lymph node dissection in the treatment of stage I and II breast cancer, with breast-conservation surgery and mastectomy.</p>
</sec>
<sec><title>Summary Background Data</title>
<p>The role of axillary dissection for staging, and as an effective means of controlling regional nodal disease, has long been recognized. As small and low-grade lesions have been detected more frequently, and as its therapeutic impact has been questioned, axillary dissection has increasingly been perceived as associated with significant complications.</p>
</sec>
<sec><title>Methods</title>
<p>Two hundred patients, 112 of whom had breast-conservation surgery with axillary dissection and 88 of whom had total mastectomy with axillary dissection, were evaluated 1 year or more after surgery for arm swelling as well as nonedema complications. All patients had arm circumference measurements at the same four sites on both the operated and nonoperated sides.</p>
</sec>
<sec><title>Results</title>
<p>No patient had an axillary recurrence. The mean difference in circumference on the nonoperated <italic>versus </italic>
operated side was 0.425 cm ± 1.39 at the midbiceps (p < 0.001), 0.315 cm ± 1.27 at the antecubital fossa (p < 0.001), 0.355 cm ± 1.53 at the midforearm (p < 0.005), and 0.055 cm ± 0.75 at the wrist (n.s.). Seven patients (3.5%) had mild swelling of the hand. Heavy and obese body habitus were the only significant predictors of edema on multivariate analysis. One hundred fifty-three (76.5%) patients had numbness or paresthesias of the medial arm and/or axilla after surgery; in 125 (82%) of these, the problem had lessened or had resolved on follow-up assessment.</p>
</sec>
<sec><title>Conclusions</title>
<p>The characterization of a level I and II axillary dissection as a procedure with significant complications does not appear justified based on this experience.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
  <front><journal-meta><journal-id journal-id-type="nlm-ta">Ann Surg</journal-id>
<journal-id journal-id-type="publisher-id">Annals of Surgery</journal-id>
<journal-title>Annals of Surgery</journal-title>
<issn pub-type="ppub">0003-4932</issn>
<issn pub-type="epub">1528-1140</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">10450733</article-id>
<article-id pub-id-type="pmc">1420861</article-id>
<article-id pub-id-type="publisher-id">0000658-199908000-00009</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Original Articles</subject>
</subj-group>
</article-categories>
<title-group><article-title>Complications of Level I and II Axillary Dissection in the Treatment of Carcinoma of the Breast</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Roses</surname>
<given-names>Daniel F.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="N0x8b4ded0.0x8c6eca8">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Brooks</surname>
<given-names>Ari D.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="N0x8b4ded0.0x8c6eca8">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Harris</surname>
<given-names>Matthew N.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="N0x8b4ded0.0x8c6eca8">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Shapiro</surname>
<given-names>Richard L.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="N0x8b4ded0.0x8c6eca8">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mitnick</surname>
<given-names>Julie</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="N0x8b4ded0.0x8c6eca8">†</xref>
</contrib>
</contrib-group>
<aff id="N0x8b4ded0.0x8c6eca8">From the *Division of Oncology, Department of Surgery, the †Department of Radiology, and the ‡Comprehensive Breast Cancer Center, Kaplan Comprehensive Cancer Center, New York University Medical Center, New York City, New York<break></break>
</aff>
<pub-date pub-type="ppub"><month>8</month>
<year>1999</year>
</pub-date>
<volume>230</volume>
<issue>2</issue>
<fpage>194</fpage>
<lpage>194</lpage>
<copyright-statement>© 1999 Lippincott Williams & Wilkins, Inc.</copyright-statement>
<abstract><sec><title>Objective</title>
<p>To assess the complications of level I and II axillary lymph node dissection in the treatment of stage I and II breast cancer, with breast-conservation surgery and mastectomy.</p>
</sec>
<sec><title>Summary Background Data</title>
<p>The role of axillary dissection for staging, and as an effective means of controlling regional nodal disease, has long been recognized. As small and low-grade lesions have been detected more frequently, and as its therapeutic impact has been questioned, axillary dissection has increasingly been perceived as associated with significant complications.</p>
</sec>
<sec><title>Methods</title>
<p>Two hundred patients, 112 of whom had breast-conservation surgery with axillary dissection and 88 of whom had total mastectomy with axillary dissection, were evaluated 1 year or more after surgery for arm swelling as well as nonedema complications. All patients had arm circumference measurements at the same four sites on both the operated and nonoperated sides.</p>
</sec>
<sec><title>Results</title>
<p>No patient had an axillary recurrence. The mean difference in circumference on the nonoperated <italic>versus </italic>
operated side was 0.425 cm ± 1.39 at the midbiceps (p < 0.001), 0.315 cm ± 1.27 at the antecubital fossa (p < 0.001), 0.355 cm ± 1.53 at the midforearm (p < 0.005), and 0.055 cm ± 0.75 at the wrist (n.s.). Seven patients (3.5%) had mild swelling of the hand. Heavy and obese body habitus were the only significant predictors of edema on multivariate analysis. One hundred fifty-three (76.5%) patients had numbness or paresthesias of the medial arm and/or axilla after surgery; in 125 (82%) of these, the problem had lessened or had resolved on follow-up assessment.</p>
</sec>
<sec><title>Conclusions</title>
<p>The characterization of a level I and II axillary dissection as a procedure with significant complications does not appear justified based on this experience.</p>
</sec>
</abstract>
</article-meta>
</front>
</pmc>
<affiliations><list></list>
<tree><noCountry><name sortKey="Brooks, Ari D" sort="Brooks, Ari D" uniqKey="Brooks A" first="Ari D." last="Brooks">Ari D. Brooks</name>
<name sortKey="Harris, Matthew N" sort="Harris, Matthew N" uniqKey="Harris M" first="Matthew N." last="Harris">Matthew N. Harris</name>
<name sortKey="Mitnick, Julie" sort="Mitnick, Julie" uniqKey="Mitnick J" first="Julie" last="Mitnick">Julie Mitnick</name>
<name sortKey="Roses, Daniel F" sort="Roses, Daniel F" uniqKey="Roses D" first="Daniel F." last="Roses">Daniel F. Roses</name>
<name sortKey="Shapiro, Richard L" sort="Shapiro, Richard L" uniqKey="Shapiro R" first="Richard L." last="Shapiro">Richard L. Shapiro</name>
</noCountry>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Ncbi/Merge

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000155 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 000155 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    Ncbi
   |étape=   Merge
   |type=    RBID
   |clé=     PMC:1420861
   |texte=   Complications of Level I and II Axillary Dissection in the Treatment of Carcinoma of the Breast
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i   -Sk "pubmed:10450733" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur le lymphœdème

Complications of Level I and II Axillary Dissection in the Treatment of Carcinoma of the Breast

Complications of Level I and II Axillary Dissection in the Treatment of Carcinoma of the Breast

Source :

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki