The clinical features and optimal treatment of anorectal malignant melanoma
Identifieur interne : 006B27 ( Ncbi/Curation ); précédent : 006B26; suivant : 006B28The clinical features and optimal treatment of anorectal malignant melanoma
Auteurs : Soomin Nam [Corée du Sud] ; Chang Woo Kim [Corée du Sud] ; Se Jin Baek [Corée du Sud] ; Hyuk Hur [Corée du Sud] ; Byung Soh Min [Corée du Sud] ; Seung Hyuk Baik [Corée du Sud] ; Nam Kyu Kim [Corée du Sud]Source :
- Annals of Surgical Treatment and Research [ 2288-6575 ] ; 2014.
Abstract
Anorectal malignant melanoma (AMM) is a very rare and aggressive disease. The purpose of this article is to review the clinical features of AMM, to understand treatment options, and optimal therapy by reviewing pertinent literature. Traditionally an abdominoperineal resection (APR) sacrificing the anal sphincter has been performed for radical resection of cancer, but recently, wide excision of AMM is attempted since quality of life after surgery is an important issue. Some authors reported that there was no difference in five-year survival between the patient who underwent an APR and wide excision. The goal of both APR and wide excision was to improve survival with R0 resection. Adjuvant chemoradiation therapy can be performed to achieve an R0 resection. AMM shows very poor prognosis. At this time, research on AMM is insufficient to suggest a treatment guideline. Thus, treatment options, and a therapeutic method should be selected carefully.
Url:
DOI: 10.4174/astr.2014.87.3.113
PubMed: 25247163
PubMed Central: 4170582
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when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Anorectal malignant melanoma (AMM) is a very rare and aggressive disease. The purpose of this article is to review the clinical features of AMM, to understand treatment options, and optimal therapy by reviewing pertinent literature. Traditionally an abdominoperineal resection (APR) sacrificing the anal sphincter has been performed for radical resection of cancer, but recently, wide excision of AMM is attempted since quality of life after surgery is an important issue. Some authors reported that there was no difference in five-year survival between the patient who underwent an APR and wide excision. The goal of both APR and wide excision was to improve survival with R0 resection. Adjuvant chemoradiation therapy can be performed to achieve an R0 resection. AMM shows very poor prognosis. At this time, research on AMM is insufficient to suggest a treatment guideline. Thus, treatment options, and a therapeutic method should be selected carefully.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Falch, C" uniqKey="Falch C">C Falch</name></author><author><name sortKey="Stojadinovic, A" uniqKey="Stojadinovic A">A Stojadinovic</name></author><author><name sortKey="Hann Von Weyhern, C" uniqKey="Hann Von Weyhern C">C Hann-von-Weyhern</name></author><author><name sortKey="Protic, M" uniqKey="Protic M">M Protic</name></author><author><name sortKey="Nissan, A" uniqKey="Nissan A">A Nissan</name></author><author><name sortKey="Faries, Mb" uniqKey="Faries M">MB Faries</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ishizone, S" uniqKey="Ishizone S">S Ishizone</name></author><author><name sortKey="Koide, N" uniqKey="Koide N">N Koide</name></author><author><name sortKey="Karasawa, F" uniqKey="Karasawa F">F Karasawa</name></author><author><name sortKey="Akita, N" 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