Axillary lymphadenectomy for breast cancer in elderly patients and fibrin glue
Identifieur interne : 005F77 ( Ncbi/Curation ); précédent : 005F76; suivant : 005F78Axillary lymphadenectomy for breast cancer in elderly patients and fibrin glue
Auteurs : Giovanni Docimo [Italie] ; Paolo Limongelli [Italie] ; Giovanni Conzo [Italie] ; Simona Gili [Italie] ; Alfonso Bosco [Italie] ; Antonia Rizzuto [Italie] ; Vincenzo Amoroso [Italie] ; Salvatore Marsico [Italie] ; Nicola Leone [Italie] ; Antonio Esposito [Italie] ; Chiara Vitiello [Italie] ; Landino Fei [Italie] ; Domenico Parmeggiani [Italie] ; Ludovico Docimo [Italie]Source :
- BMC Surgery [ 1471-2482 ] ; 2013.
Abstract
Axillary lymphadenectomy or sentinel biopsy is integral part of breast cancer treatment, yet seroma formation occurs in 15-85% of cases. Among methods employed to reduce seroma magnitude and duration, fibrin glue has been proposed in numerous studies with controversial results.
Thirty patients over 60 years underwent quadrantectomy or mastectomy with level I/II axillary lymphadenectomy; a suction drain was fitted in all patients. Fibrin glue spray were applied to the axillary fossa in 15 patients; the other 15 patients were treated with harmonic scalpel.
Suction drainage was removed between post-operative Days 3 and 4. Seroma magnitude and duration were not significant in patients receiving fibrin glue compared with the harmonic scalpel group.
Use of fibrin glue does not always prevent seroma formation, but can reduce seroma magnitude, duration and necessary evacuative punctures.
Url:
DOI: 10.1186/1471-2482-13-S2-S8
PubMed: 24266959
PubMed Central: 3851152
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PMC:3851152Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Axillary lymphadenectomy for breast cancer in elderly patients and fibrin glue</title>
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<author><name sortKey="Amoroso, Vincenzo" sort="Amoroso, Vincenzo" uniqKey="Amoroso V" first="Vincenzo" last="Amoroso">Vincenzo Amoroso</name>
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<author><name sortKey="Marsico, Salvatore" sort="Marsico, Salvatore" uniqKey="Marsico S" first="Salvatore" last="Marsico">Salvatore Marsico</name>
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<author><name sortKey="Leone, Nicola" sort="Leone, Nicola" uniqKey="Leone N" first="Nicola" last="Leone">Nicola Leone</name>
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<author><name sortKey="Esposito, Antonio" sort="Esposito, Antonio" uniqKey="Esposito A" first="Antonio" last="Esposito">Antonio Esposito</name>
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<author><name sortKey="Vitiello, Chiara" sort="Vitiello, Chiara" uniqKey="Vitiello C" first="Chiara" last="Vitiello">Chiara Vitiello</name>
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<author><name sortKey="Fei, Landino" sort="Fei, Landino" uniqKey="Fei L" first="Landino" last="Fei">Landino Fei</name>
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<author><name sortKey="Parmeggiani, Domenico" sort="Parmeggiani, Domenico" uniqKey="Parmeggiani D" first="Domenico" last="Parmeggiani">Domenico Parmeggiani</name>
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<author><name sortKey="Docimo, Ludovico" sort="Docimo, Ludovico" uniqKey="Docimo L" first="Ludovico" last="Docimo">Ludovico Docimo</name>
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<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>Axillary lymphadenectomy or sentinel biopsy is integral part of breast cancer treatment, yet seroma formation occurs in 15-85% of cases. Among methods employed to reduce seroma magnitude and duration, fibrin glue has been proposed in numerous studies with controversial results.</p>
</sec>
<sec><title>Methods</title>
<p>Thirty patients over 60 years underwent quadrantectomy or mastectomy with level I/II axillary lymphadenectomy; a suction drain was fitted in all patients. Fibrin glue spray were applied to the axillary fossa in 15 patients; the other 15 patients were treated with harmonic scalpel.</p>
</sec>
<sec><title>Results</title>
<p>Suction drainage was removed between post-operative Days 3 and 4. Seroma magnitude and duration were not significant in patients receiving fibrin glue compared with the harmonic scalpel group.</p>
</sec>
<sec><title>Conclusions</title>
<p>Use of fibrin glue does not always prevent seroma formation, but can reduce seroma magnitude, duration and necessary evacuative punctures.</p>
</sec>
</div>
</front>
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