Effect of terbutaline on peripheral lymph flow, protein concentration and transport, and edema formation after thermal injury in rabbits.
Identifieur interne : 009C40 ( Ncbi/Checkpoint ); précédent : 009C39; suivant : 009C41Effect of terbutaline on peripheral lymph flow, protein concentration and transport, and edema formation after thermal injury in rabbits.
Auteurs : G. Szabo ; Z. Magyar ; E. PoschSource :
- Lymphology [ 0024-7766 ] ; 1985.
Descripteurs français
- KwdFr :
- MESH :
- métabolisme : Espace extracellulaire, Protéines.
- pharmacologie : Terbutaline.
- physiologie : Système lymphatique.
- physiopathologie : Brûlures.
- Animaux, Femelle, Lapins, Lymphoedème, Membre pelvien, Mâle, Système lymphatique, Transport biologique.
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Proteins.
- drug effects : Lymphatic System.
- metabolism : Extracellular Space.
- chemical , pharmacology : Terbutaline.
- physiology : Lymphatic System.
- physiopathology : Burns.
- prevention & control : Lymphedema.
- Animals, Biological Transport, Female, Hindlimb, Male, Rabbits.
Abstract
In the rabbit, intraarterial infusion of 5 micrograms/min of terbutaline within the first two hours after moderate thermal injury prevents edema and reduces augmented lymph flow, lymphatic protein transport, and tissue fluid protein concentration. Terbutaline, however, fails to prevent edema 4 hours after thermal injury although the increase of leg volume (24%) is less than in the untreated, burned control leg (56%). A higher dose of terbutaline (15 micrograms/min) also fails to block edema 4 hours after burning and its effect on leg volume, lymph flow, and lymphatic protein concentration is similar to that of 5 micrograms/min infusion. Terbutaline does not alter the extent of tissue injury after burning as the increase in tissue fluid lactic dehydrogenase and potassium are similar with "treated" and "untreated" burns.
PubMed: 4033197
Affiliations:
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pubmed:4033197Le document en format XML
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<author><name sortKey="Magyar, Z" sort="Magyar, Z" uniqKey="Magyar Z" first="Z" last="Magyar">Z. Magyar</name>
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<author><name sortKey="Posch, E" sort="Posch, E" uniqKey="Posch E" first="E" last="Posch">E. Posch</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Effect of terbutaline on peripheral lymph flow, protein concentration and transport, and edema formation after thermal injury in rabbits.</title>
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<author><name sortKey="Magyar, Z" sort="Magyar, Z" uniqKey="Magyar Z" first="Z" last="Magyar">Z. Magyar</name>
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<author><name sortKey="Posch, E" sort="Posch, E" uniqKey="Posch E" first="E" last="Posch">E. Posch</name>
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<series><title level="j">Lymphology</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Biological Transport</term>
<term>Burns (physiopathology)</term>
<term>Extracellular Space (metabolism)</term>
<term>Female</term>
<term>Hindlimb</term>
<term>Lymphatic System (drug effects)</term>
<term>Lymphatic System (physiology)</term>
<term>Lymphedema (prevention & control)</term>
<term>Male</term>
<term>Proteins (metabolism)</term>
<term>Rabbits</term>
<term>Terbutaline (pharmacology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Brûlures (physiopathologie)</term>
<term>Espace extracellulaire (métabolisme)</term>
<term>Femelle</term>
<term>Lapins</term>
<term>Lymphoedème ()</term>
<term>Membre pelvien</term>
<term>Mâle</term>
<term>Protéines (métabolisme)</term>
<term>Système lymphatique ()</term>
<term>Système lymphatique (physiologie)</term>
<term>Terbutaline (pharmacologie)</term>
<term>Transport biologique</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Proteins</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Lymphatic System</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Extracellular Space</term>
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<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Espace extracellulaire</term>
<term>Protéines</term>
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</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Terbutaline</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Système lymphatique</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Lymphatic System</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Brûlures</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Burns</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Lymphedema</term>
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<term>Biological Transport</term>
<term>Female</term>
<term>Hindlimb</term>
<term>Male</term>
<term>Rabbits</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Femelle</term>
<term>Lapins</term>
<term>Lymphoedème</term>
<term>Membre pelvien</term>
<term>Mâle</term>
<term>Système lymphatique</term>
<term>Transport biologique</term>
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<front><div type="abstract" xml:lang="en">In the rabbit, intraarterial infusion of 5 micrograms/min of terbutaline within the first two hours after moderate thermal injury prevents edema and reduces augmented lymph flow, lymphatic protein transport, and tissue fluid protein concentration. Terbutaline, however, fails to prevent edema 4 hours after thermal injury although the increase of leg volume (24%) is less than in the untreated, burned control leg (56%). A higher dose of terbutaline (15 micrograms/min) also fails to block edema 4 hours after burning and its effect on leg volume, lymph flow, and lymphatic protein concentration is similar to that of 5 micrograms/min infusion. Terbutaline does not alter the extent of tissue injury after burning as the increase in tissue fluid lactic dehydrogenase and potassium are similar with "treated" and "untreated" burns.</div>
</front>
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<affiliations><list></list>
<tree><noCountry><name sortKey="Magyar, Z" sort="Magyar, Z" uniqKey="Magyar Z" first="Z" last="Magyar">Z. Magyar</name>
<name sortKey="Posch, E" sort="Posch, E" uniqKey="Posch E" first="E" last="Posch">E. Posch</name>
<name sortKey="Szabo, G" sort="Szabo, G" uniqKey="Szabo G" first="G" last="Szabo">G. Szabo</name>
</noCountry>
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