The effects of silica on lymph nodes and vessels--a possible mechanism in the pathogenesis of non-filarial endemic elephantiasis.
Identifieur interne : 009518 ( Ncbi/Checkpoint ); précédent : 009517; suivant : 009519The effects of silica on lymph nodes and vessels--a possible mechanism in the pathogenesis of non-filarial endemic elephantiasis.
Auteurs : N C Fyfe ; E W PriceSource :
- Transactions of the Royal Society of Tropical Medicine and Hygiene [ 0035-9203 ] ; 1985.
Descripteurs français
- KwdFr :
- Animaux, Facteurs temps, Femelle, Lapins, Lymphoedème (), Lymphographie, Macrophages (anatomopathologie), Mâle, Noeuds lymphatiques (), Noeuds lymphatiques (anatomopathologie), Silice (effets indésirables), Système lymphatique (), Système lymphatique (anatomopathologie), Éléphantiasis (), Éléphantiasis (anatomopathologie).
- MESH :
- anatomopathologie : Macrophages, Noeuds lymphatiques, Système lymphatique, Éléphantiasis.
- effets indésirables : Silice.
- Animaux, Facteurs temps, Femelle, Lapins, Lymphoedème, Lymphographie, Mâle, Noeuds lymphatiques, Système lymphatique, Éléphantiasis.
English descriptors
- KwdEn :
- Animals, Elephantiasis (chemically induced), Elephantiasis (pathology), Female, Lymph Nodes (drug effects), Lymph Nodes (pathology), Lymphatic System (drug effects), Lymphatic System (pathology), Lymphedema (chemically induced), Lymphography, Macrophages (pathology), Male, Rabbits, Silicon Dioxide (adverse effects), Time Factors.
- MESH :
- chemical , adverse effects : Silicon Dioxide.
- chemically induced : Elephantiasis, Lymphedema.
- drug effects : Lymph Nodes, Lymphatic System.
- pathology : Elephantiasis, Lymph Nodes, Lymphatic System, Macrophages.
- Animals, Female, Lymphography, Male, Rabbits, Time Factors.
Abstract
Non-filarial tropical elephantiasis, which occurs in certain volcanic areas of the world, has been postulated to be an obstructive lymphopathy due to the fibrogenic effects of silica absorbed through the plantar skin of bare-footed people. Animal experiments involving the direct intralymphatic injection of fine silica particles have been carried out in order to assess the extent to which this substance can engender lymphatic obstruction and to determine its main site of action. Intralymphatic silica provoked an immediate and intense macrophage reaction with later fibrosis both within lymph vessels and to a lesser extent within lymph nodes. Lymphography indicated that the consequent obstruction resulted more from the effects of silica on vessels than on nodes.
PubMed: 3006293
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 006883
- to stream PubMed, to step Curation: 006883
- to stream PubMed, to step Checkpoint: 006883
- to stream Ncbi, to step Merge: 009518
- to stream Ncbi, to step Curation: 009518
Links to Exploration step
pubmed:3006293Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The effects of silica on lymph nodes and vessels--a possible mechanism in the pathogenesis of non-filarial endemic elephantiasis.</title>
<author><name sortKey="Fyfe, N C" sort="Fyfe, N C" uniqKey="Fyfe N" first="N C" last="Fyfe">N C Fyfe</name>
</author>
<author><name sortKey="Price, E W" sort="Price, E W" uniqKey="Price E" first="E W" last="Price">E W Price</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1985">1985</date>
<idno type="RBID">pubmed:3006293</idno>
<idno type="pmid">3006293</idno>
<idno type="wicri:Area/PubMed/Corpus">006883</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">006883</idno>
<idno type="wicri:Area/PubMed/Curation">006883</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">006883</idno>
<idno type="wicri:Area/PubMed/Checkpoint">006883</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">006883</idno>
<idno type="wicri:Area/Ncbi/Merge">009518</idno>
<idno type="wicri:Area/Ncbi/Curation">009518</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">009518</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">The effects of silica on lymph nodes and vessels--a possible mechanism in the pathogenesis of non-filarial endemic elephantiasis.</title>
<author><name sortKey="Fyfe, N C" sort="Fyfe, N C" uniqKey="Fyfe N" first="N C" last="Fyfe">N C Fyfe</name>
</author>
<author><name sortKey="Price, E W" sort="Price, E W" uniqKey="Price E" first="E W" last="Price">E W Price</name>
</author>
</analytic>
<series><title level="j">Transactions of the Royal Society of Tropical Medicine and Hygiene</title>
<idno type="ISSN">0035-9203</idno>
<imprint><date when="1985" type="published">1985</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Elephantiasis (chemically induced)</term>
<term>Elephantiasis (pathology)</term>
<term>Female</term>
<term>Lymph Nodes (drug effects)</term>
<term>Lymph Nodes (pathology)</term>
<term>Lymphatic System (drug effects)</term>
<term>Lymphatic System (pathology)</term>
<term>Lymphedema (chemically induced)</term>
<term>Lymphography</term>
<term>Macrophages (pathology)</term>
<term>Male</term>
<term>Rabbits</term>
<term>Silicon Dioxide (adverse effects)</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Lapins</term>
<term>Lymphoedème ()</term>
<term>Lymphographie</term>
<term>Macrophages (anatomopathologie)</term>
<term>Mâle</term>
<term>Noeuds lymphatiques ()</term>
<term>Noeuds lymphatiques (anatomopathologie)</term>
<term>Silice (effets indésirables)</term>
<term>Système lymphatique ()</term>
<term>Système lymphatique (anatomopathologie)</term>
<term>Éléphantiasis ()</term>
<term>Éléphantiasis (anatomopathologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Silicon Dioxide</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Macrophages</term>
<term>Noeuds lymphatiques</term>
<term>Système lymphatique</term>
<term>Éléphantiasis</term>
</keywords>
<keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Elephantiasis</term>
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Lymph Nodes</term>
<term>Lymphatic System</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Silice</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Elephantiasis</term>
<term>Lymph Nodes</term>
<term>Lymphatic System</term>
<term>Macrophages</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Female</term>
<term>Lymphography</term>
<term>Male</term>
<term>Rabbits</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Lapins</term>
<term>Lymphoedème</term>
<term>Lymphographie</term>
<term>Mâle</term>
<term>Noeuds lymphatiques</term>
<term>Système lymphatique</term>
<term>Éléphantiasis</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Non-filarial tropical elephantiasis, which occurs in certain volcanic areas of the world, has been postulated to be an obstructive lymphopathy due to the fibrogenic effects of silica absorbed through the plantar skin of bare-footed people. Animal experiments involving the direct intralymphatic injection of fine silica particles have been carried out in order to assess the extent to which this substance can engender lymphatic obstruction and to determine its main site of action. Intralymphatic silica provoked an immediate and intense macrophage reaction with later fibrosis both within lymph vessels and to a lesser extent within lymph nodes. Lymphography indicated that the consequent obstruction resulted more from the effects of silica on vessels than on nodes.</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Fyfe, N C" sort="Fyfe, N C" uniqKey="Fyfe N" first="N C" last="Fyfe">N C Fyfe</name>
<name sortKey="Price, E W" sort="Price, E W" uniqKey="Price E" first="E W" last="Price">E W Price</name>
</noCountry>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Ncbi/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 009518 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 009518 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Ncbi |étape= Checkpoint |type= RBID |clé= pubmed:3006293 |texte= The effects of silica on lymph nodes and vessels--a possible mechanism in the pathogenesis of non-filarial endemic elephantiasis. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:3006293" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \ | NlmPubMed2Wicri -a LymphedemaV1
![]() | This area was generated with Dilib version V0.6.31. | ![]() |