CD146 is required for VEGF-C-induced lymphatic sprouting during lymphangiogenesis
Identifieur interne : 009354 ( Ncbi/Checkpoint ); précédent : 009353; suivant : 009355CD146 is required for VEGF-C-induced lymphatic sprouting during lymphangiogenesis
Auteurs : Huiwen Yan [République populaire de Chine] ; Chunxia Zhang [République populaire de Chine] ; Zhaoqing Wang [République populaire de Chine] ; Tao Tu [République populaire de Chine] ; Hongxia Duan [République populaire de Chine] ; Yongting Luo [République populaire de Chine] ; Jing Feng [République populaire de Chine] ; Feng Liu [République populaire de Chine] ; Xiyun Yan [République populaire de Chine]Source :
- Scientific Reports [ 2045-2322 ] ; 2017.
Abstract
VEGF-C is essential for lymphangiogenesis during development and tumor progression. VEGFR-3 is the well-known cognate receptor of VEGF-C to regulate lymphatic migration and proliferation, but the receptor of VEGF-C in regulating lymphatic sprouting, the initiating step of lymphangiogenesis, still remains elusive. Here we use both
Url:
DOI: 10.1038/s41598-017-06637-7
PubMed: 28785085
PubMed Central: 5547131
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000E44
- to stream Pmc, to step Curation: 000E43
- to stream Pmc, to step Checkpoint: 000373
- to stream Ncbi, to step Merge: 009354
- to stream Ncbi, to step Curation: 009354
Links to Exploration step
PMC:5547131Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">CD146 is required for VEGF-C-induced lymphatic sprouting during lymphangiogenesis</title><author><name sortKey="Yan, Huiwen" sort="Yan, Huiwen" uniqKey="Yan H" first="Huiwen" last="Yan">Huiwen Yan</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1797 8419</institution-id><institution-id institution-id-type="GRID">grid.410726.6</institution-id><institution>College of Life Sciences,</institution><institution>University of Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100049 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Chunxia" sort="Zhang, Chunxia" uniqKey="Zhang C" first="Chunxia" last="Zhang">Chunxia Zhang</name><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>State Key Laboratory of Membrane Biology, Institute of Zoology,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1797 8419</institution-id><institution-id institution-id-type="GRID">grid.410726.6</institution-id><institution>College of Life Sciences,</institution><institution>University of Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100049 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Zhaoqing" sort="Wang, Zhaoqing" uniqKey="Wang Z" first="Zhaoqing" last="Wang">Zhaoqing Wang</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Tu, Tao" sort="Tu, Tao" uniqKey="Tu T" first="Tao" last="Tu">Tao Tu</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Duan, Hongxia" sort="Duan, Hongxia" uniqKey="Duan H" first="Hongxia" last="Duan">Hongxia Duan</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Luo, Yongting" sort="Luo, Yongting" uniqKey="Luo Y" first="Yongting" last="Luo">Yongting Luo</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Feng, Jing" sort="Feng, Jing" uniqKey="Feng J" first="Jing" last="Feng">Jing Feng</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Feng" sort="Liu, Feng" uniqKey="Liu F" first="Feng" last="Liu">Feng Liu</name><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>State Key Laboratory of Membrane Biology, Institute of Zoology,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Yan, Xiyun" sort="Yan, Xiyun" uniqKey="Yan X" first="Xiyun" last="Yan">Xiyun Yan</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1797 8419</institution-id><institution-id institution-id-type="GRID">grid.410726.6</institution-id><institution>College of Life Sciences,</institution><institution>University of Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100049 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28785085</idno><idno type="pmc">5547131</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547131</idno><idno type="RBID">PMC:5547131</idno><idno type="doi">10.1038/s41598-017-06637-7</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">000E44</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000E44</idno><idno type="wicri:Area/Pmc/Curation">000E43</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000E43</idno><idno type="wicri:Area/Pmc/Checkpoint">000373</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000373</idno><idno type="wicri:Area/Ncbi/Merge">009354</idno><idno type="wicri:Area/Ncbi/Curation">009354</idno><idno type="wicri:Area/Ncbi/Checkpoint">009354</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">CD146 is required for VEGF-C-induced lymphatic sprouting during lymphangiogenesis</title><author><name sortKey="Yan, Huiwen" sort="Yan, Huiwen" uniqKey="Yan H" first="Huiwen" last="Yan">Huiwen Yan</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1797 8419</institution-id><institution-id institution-id-type="GRID">grid.410726.6</institution-id><institution>College of Life Sciences,</institution><institution>University of Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100049 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Chunxia" sort="Zhang, Chunxia" uniqKey="Zhang C" first="Chunxia" last="Zhang">Chunxia Zhang</name><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>State Key Laboratory of Membrane Biology, Institute of Zoology,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1797 8419</institution-id><institution-id institution-id-type="GRID">grid.410726.6</institution-id><institution>College of Life Sciences,</institution><institution>University of Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100049 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Zhaoqing" sort="Wang, Zhaoqing" uniqKey="Wang Z" first="Zhaoqing" last="Wang">Zhaoqing Wang</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Tu, Tao" sort="Tu, Tao" uniqKey="Tu T" first="Tao" last="Tu">Tao Tu</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Duan, Hongxia" sort="Duan, Hongxia" uniqKey="Duan H" first="Hongxia" last="Duan">Hongxia Duan</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Luo, Yongting" sort="Luo, Yongting" uniqKey="Luo Y" first="Yongting" last="Luo">Yongting Luo</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Feng, Jing" sort="Feng, Jing" uniqKey="Feng J" first="Jing" last="Feng">Jing Feng</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Feng" sort="Liu, Feng" uniqKey="Liu F" first="Feng" last="Liu">Feng Liu</name><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>State Key Laboratory of Membrane Biology, Institute of Zoology,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Yan, Xiyun" sort="Yan, Xiyun" uniqKey="Yan X" first="Xiyun" last="Yan">Xiyun Yan</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100101 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1797 8419</institution-id><institution-id institution-id-type="GRID">grid.410726.6</institution-id><institution>College of Life Sciences,</institution><institution>University of Chinese Academy of Sciences,</institution></institution-wrap>Beijing, 100049 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing</wicri:regionArea></affiliation></author></analytic><series><title level="j">Scientific Reports</title><idno type="eISSN">2045-2322</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="Par1">VEGF-C is essential for lymphangiogenesis during development and tumor progression. VEGFR-3 is the well-known cognate receptor of VEGF-C to regulate lymphatic migration and proliferation, but the receptor of VEGF-C in regulating lymphatic sprouting, the initiating step of lymphangiogenesis, still remains elusive. Here we use both <italic>in vitro</italic> and <italic>in vivo</italic> methods to demonstrate CD146 as a receptor of VEGF-C to regulate lymphangiogenesis, especially at the sprouting step. Mechanistically, CD146 selectively activates the downstream p38 kinase, upon VEGF-C stimulation, to regulate lymphatic sprouting. Moreover, CD146 can also activate ERK to mediate VEGF-C regulation of the subsequent proliferation and migration of lymphatic endothelial cells. In zebrafish embryos, knockdown or dysfunction of CD146 results in similar developmental defects in lymphatic sprouting, capillary network, parachordal lymphangioblast (PL), and thoracic duct (TD) similar to down-regulation of VEGF-C. Altogether, our data reveals a critical role of CD146 to mediate VEGF-C signaling pathway in lymphangiogenesis.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Tammela, T" uniqKey="Tammela T">T Tammela</name></author><author><name sortKey="Alitalo, K" uniqKey="Alitalo K">K Alitalo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y Yang</name></author><author><name sortKey="Oliver, G" uniqKey="Oliver G">G Oliver</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mulligan, Ts" uniqKey="Mulligan T">TS Mulligan</name></author><author><name sortKey="Weinstein, Bm" uniqKey="Weinstein B">BM Weinstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Karpanen, T" uniqKey="Karpanen T">T Karpanen</name></author><author><name sortKey="Alitalo, K" uniqKey="Alitalo K">K Alitalo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Plate, K" uniqKey="Plate K">K Plate</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Folkman, J" uniqKey="Folkman J">J Folkman</name></author><author><name sortKey="Kaipainen, A" uniqKey="Kaipainen A">A Kaipainen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jussila, L" uniqKey="Jussila L">L Jussila</name></author><author><name sortKey="Alitalo, K" uniqKey="Alitalo K">K Alitalo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Karkkainen, Mj" uniqKey="Karkkainen M">MJ Karkkainen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuchler, Am" uniqKey="Kuchler A">AM Kuchler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Coso, S" uniqKey="Coso S">S Coso</name></author><author><name sortKey="Bovay, E" uniqKey="Bovay E">E Bovay</name></author><author><name sortKey="Petrova, Tv" uniqKey="Petrova T">TV Petrova</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fevurly, Rd" uniqKey="Fevurly R">RD Fevurly</name></author><author><name sortKey="Hasso, S" uniqKey="Hasso S">S Hasso</name></author><author><name sortKey="Fye, A" uniqKey="Fye A">A Fye</name></author><author><name sortKey="Fishman, Sj" uniqKey="Fishman S">SJ Fishman</name></author><author><name sortKey="Chan, J" uniqKey="Chan J">J Chan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Salameh, A" uniqKey="Salameh A">A Salameh</name></author><author><name sortKey="Galvagni, F" uniqKey="Galvagni F">F Galvagni</name></author><author><name sortKey="Bardelli, M" uniqKey="Bardelli M">M Bardelli</name></author><author><name sortKey="Bussolino, F" uniqKey="Bussolino F">F Bussolino</name></author><author><name sortKey="Oliviero, S" uniqKey="Oliviero S">S Oliviero</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Veikkola, T" uniqKey="Veikkola T">T Veikkola</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tammela, T" uniqKey="Tammela T">T Tammela</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, L" uniqKey="Zhang L">L Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yan, X" uniqKey="Yan X">X Yan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jiang, T" uniqKey="Jiang T">T Jiang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Petrova, Tv" uniqKey="Petrova T">TV Petrova</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Seo, S" uniqKey="Seo S">S Seo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Makinen, T" uniqKey="Makinen T">T Makinen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hogan, Bm" uniqKey="Hogan B">BM Hogan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ando, T" uniqKey="Ando T">T Ando</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iljin, K" uniqKey="Iljin K">K Iljin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Joukov, V" uniqKey="Joukov V">V Joukov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tu, T" uniqKey="Tu T">T Tu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kang, Y" uniqKey="Kang Y">Y Kang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="So, Jh" uniqKey="So J">JH So</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dumont, Dj" uniqKey="Dumont D">DJ Dumont</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bu, P" uniqKey="Bu P">P Bu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alitalo, K" uniqKey="Alitalo K">K Alitalo</name></author><author><name sortKey="Tammela, T" uniqKey="Tammela T">T Tammela</name></author><author><name sortKey="Petrova, Tv" uniqKey="Petrova T">TV Petrova</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stacker, Sa" uniqKey="Stacker S">SA Stacker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, E" uniqKey="Lee E">E Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Min, Y" uniqKey="Min Y">Y Min</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Christianson, Dr" uniqKey="Christianson D">DR Christianson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="He, Y" uniqKey="He Y">Y He</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, J" uniqKey="Lin J">J Lin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shimizu, K" uniqKey="Shimizu K">K Shimizu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roberts, N" uniqKey="Roberts N">N Roberts</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, Z" uniqKey="Chen Z">Z Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Blacher, S" uniqKey="Blacher S">S Blacher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lawson, Nd" uniqKey="Lawson N">ND Lawson</name></author><author><name sortKey="Weinstein, Bm" uniqKey="Weinstein B">BM Weinstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Proulx, K" uniqKey="Proulx K">K Proulx</name></author><author><name sortKey="Lu, A" uniqKey="Lu A">A Lu</name></author><author><name sortKey="Sumanas, S" uniqKey="Sumanas S">S Sumanas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, P" uniqKey="Zhang P">P Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wei, Y" uniqKey="Wei Y">Y Wei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoffman, Sj" uniqKey="Hoffman S">SJ Hoffman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yaniv, K" uniqKey="Yaniv K">K Yaniv</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Yan, Huiwen" sort="Yan, Huiwen" uniqKey="Yan H" first="Huiwen" last="Yan">Huiwen Yan</name></noRegion><name sortKey="Duan, Hongxia" sort="Duan, Hongxia" uniqKey="Duan H" first="Hongxia" last="Duan">Hongxia Duan</name><name sortKey="Feng, Jing" sort="Feng, Jing" uniqKey="Feng J" first="Jing" last="Feng">Jing Feng</name><name sortKey="Liu, Feng" sort="Liu, Feng" uniqKey="Liu F" first="Feng" last="Liu">Feng Liu</name><name sortKey="Luo, Yongting" sort="Luo, Yongting" uniqKey="Luo Y" first="Yongting" last="Luo">Yongting Luo</name><name sortKey="Tu, Tao" sort="Tu, Tao" uniqKey="Tu T" first="Tao" last="Tu">Tao Tu</name><name sortKey="Wang, Zhaoqing" sort="Wang, Zhaoqing" uniqKey="Wang Z" first="Zhaoqing" last="Wang">Zhaoqing Wang</name><name sortKey="Yan, Huiwen" sort="Yan, Huiwen" uniqKey="Yan H" first="Huiwen" last="Yan">Huiwen Yan</name><name sortKey="Yan, Xiyun" sort="Yan, Xiyun" uniqKey="Yan X" first="Xiyun" last="Yan">Xiyun Yan</name><name sortKey="Yan, Xiyun" sort="Yan, Xiyun" uniqKey="Yan X" first="Xiyun" last="Yan">Xiyun Yan</name><name sortKey="Zhang, Chunxia" sort="Zhang, Chunxia" uniqKey="Zhang C" first="Chunxia" last="Zhang">Chunxia Zhang</name><name sortKey="Zhang, Chunxia" sort="Zhang, Chunxia" uniqKey="Zhang C" first="Chunxia" last="Zhang">Chunxia Zhang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Ncbi/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 009354 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 009354 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Ncbi
|étape= Checkpoint
|type= RBID
|clé= PMC:5547131
|texte= CD146 is required for VEGF-C-induced lymphatic sprouting during lymphangiogenesis
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:28785085" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |