Endoscopic nipple sparing mastectomy with immediate implant-based reconstruction versus breast conserving surgery: a long-term study
Identifieur interne : 008F33 ( Ncbi/Checkpoint ); précédent : 008F32; suivant : 008F34Endoscopic nipple sparing mastectomy with immediate implant-based reconstruction versus breast conserving surgery: a long-term study
Auteurs : Junze Du [République populaire de Chine] ; Quankun Liang [République populaire de Chine] ; Xiaowei Qi [République populaire de Chine] ; Jia Ming [République populaire de Chine] ; Jing Liu [République populaire de Chine] ; Ling Zhong [République populaire de Chine] ; Linjun Fan [République populaire de Chine] ; Jun Jiang [République populaire de Chine]Source :
- Scientific Reports [ 2045-2322 ] ; 2017.
Abstract
To evaluate the differences between endoscopic nipple sparing mastectomy (ENSM) with immediate implant-based reconstruction and breast conserving surgery(BCS) applied to early-stage breast cancer in postoperative outcomes, function, and cosmesis. we made a prospective, non-randomized study reviewed a total of 346 cases of breast cancer from January 2007 to December 2011, including 189 cases of BCS and 157 cases of ENSM. All the patients were followed up to April 2016, with a median follow-up time of 74 months. The operative time, blood loss and drainage, postoperative complications, postoperative cosmesis, local recurrence rate, disease-free survival rate and overall survival rate of the two groups were compared. we found out that the operative time of ENSM was longer than that of BCS. There was no difference in blood loss and drainage, the postoperative complications, the disease-free survival rate and overall survival rate between the two groups. In regarding to cosmesis, patients in the ENSM group were more likely to get a satisfactory postoperative breast appearance. we reached a conclusion that ENSM is a safe and effective operative method retainingadvantages of TSSM to further improve the postoperative cosmetic effect, without increasing other risks. The surgery provides a new choice for patients with early-stage breast cancer.
Url:
DOI: 10.1038/srep45636
PubMed: 28361955
PubMed Central: 5374499
Affiliations:
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see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Jing" sort="Liu, Jing" uniqKey="Liu J" first="Jing" last="Liu">Jing Liu</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Breast surgery, Southwest Hospital, the Third Military Medical University</institution>, Chongqing 400038,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zhong, Ling" sort="Zhong, Ling" uniqKey="Zhong L" first="Ling" last="Zhong">Ling Zhong</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Breast surgery, Southwest Hospital, the Third Military Medical University</institution>, Chongqing 400038,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Fan, Linjun" sort="Fan, Linjun" uniqKey="Fan L" first="Linjun" last="Fan">Linjun Fan</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Breast surgery, Southwest Hospital, the Third Military Medical University</institution>, Chongqing 400038,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Jiang, Jun" sort="Jiang, Jun" uniqKey="Jiang J" first="Jun" last="Jiang">Jun Jiang</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Breast surgery, Southwest Hospital, the Third Military Medical University</institution>, Chongqing 400038,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country 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level="a" type="main">Endoscopic nipple sparing mastectomy with immediate implant-based reconstruction versus breast conserving surgery: a long-term study</title><author><name sortKey="Du, Junze" sort="Du, Junze" uniqKey="Du J" first="Junze" last="Du">Junze Du</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Breast surgery, Southwest Hospital, the Third Military Medical University</institution>, Chongqing 400038,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Liang, Quankun" sort="Liang, Quankun" uniqKey="Liang Q" first="Quankun" last="Liang">Quankun Liang</name><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Head-neck surgery, Tumor Hospital, Guangxi Medical University</institution>, Guangxi, 530021,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Qi, Xiaowei" sort="Qi, Xiaowei" uniqKey="Qi X" first="Xiaowei" last="Qi">Xiaowei Qi</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Breast surgery, Southwest Hospital, the Third Military Medical University</institution>, Chongqing 400038,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ming, Jia" sort="Ming, Jia" uniqKey="Ming J" first="Jia" last="Ming">Jia Ming</name><affiliation wicri:level="1"><nlm:aff id="a3"><institution>Three glands surgery, the Second Affiliated Hospital, Chongqing Medical University</institution>, Chongqing 400010,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Jing" sort="Liu, Jing" uniqKey="Liu J" first="Jing" last="Liu">Jing Liu</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Breast surgery, Southwest Hospital, the Third Military Medical University</institution>, Chongqing 400038,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zhong, Ling" sort="Zhong, Ling" uniqKey="Zhong L" first="Ling" last="Zhong">Ling Zhong</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Breast surgery, Southwest Hospital, the Third Military Medical University</institution>, Chongqing 400038,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Fan, Linjun" sort="Fan, Linjun" uniqKey="Fan L" first="Linjun" last="Fan">Linjun Fan</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Breast surgery, Southwest Hospital, the Third Military Medical University</institution>, Chongqing 400038,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Jiang, Jun" sort="Jiang, Jun" uniqKey="Jiang J" first="Jun" last="Jiang">Jun Jiang</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Breast surgery, Southwest Hospital, the Third Military Medical University</institution>, Chongqing 400038,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Scientific Reports</title><idno type="eISSN">2045-2322</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>To evaluate the differences between endoscopic nipple sparing mastectomy (ENSM) with immediate implant-based reconstruction and breast conserving surgery(BCS) applied to early-stage breast cancer in postoperative outcomes, function, and cosmesis. we made a prospective, non-randomized study reviewed a total of 346 cases of breast cancer from January 2007 to December 2011, including 189 cases of BCS and 157 cases of ENSM. All the patients were followed up to April 2016, with a median follow-up time of 74 months. The operative time, blood loss and drainage, postoperative complications, postoperative cosmesis, local recurrence rate, disease-free survival rate and overall survival rate of the two groups were compared. we found out that the operative time of ENSM was longer than that of BCS. There was no difference in blood loss and drainage, the postoperative complications, the disease-free survival rate and overall survival rate between the two groups. In regarding to cosmesis, patients in the ENSM group were more likely to get a satisfactory postoperative breast appearance. we reached a conclusion that ENSM is a safe and effective operative method retainingadvantages of TSSM to further improve the postoperative cosmetic effect, without increasing other risks. The surgery provides a new choice for patients with early-stage breast cancer.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Chen, W" uniqKey="Chen W">W. Chen</name></author><author><name sortKey="Zheng, R" uniqKey="Zheng R">R. Zheng</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S. Zhang</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S. Zhang</name></author><author><name sortKey="He, J" uniqKey="He J">J. He</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Desantis, C E" uniqKey="Desantis C">C. E. DeSantis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Howlader, N" uniqKey="Howlader N">N. Howlader</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Veronesi, U" uniqKey="Veronesi U">U. 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Benediktsson</name></author><author><name sortKey="Perbeck, L" uniqKey="Perbeck L">L. Perbeck</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barry, M" uniqKey="Barry M">M. Barry</name></author><author><name sortKey="Kell, M R" uniqKey="Kell M">M. R. Kell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, C" uniqKey="Liu C">C. Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="T Nseth, K A" uniqKey="T Nseth K">K. A. Tønseth</name></author><author><name sortKey="Hokland, B M" uniqKey="Hokland B">B. M. Hokland</name></author><author><name sortKey="Tindholdt, T T" uniqKey="Tindholdt T">T. T. Tindholdt</name></author><author><name sortKey="Abyholm, F E" uniqKey="Abyholm F">F. E. Abyholm</name></author><author><name sortKey="Stavem, K" uniqKey="Stavem K">K. Stavem</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gill, P S" uniqKey="Gill P">P. S. Gill</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mehrara, B J" uniqKey="Mehrara B">B. J. Mehrara</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albornoz, C R" uniqKey="Albornoz C">C. R. Albornoz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Disa, J J" uniqKey="Disa J">J. J. Disa</name></author><author><name sortKey="Disa, J J" uniqKey="Disa J">J. J. Disa</name></author></analytic></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Du, Junze" sort="Du, Junze" uniqKey="Du J" first="Junze" last="Du">Junze Du</name></noRegion><name sortKey="Fan, Linjun" sort="Fan, Linjun" uniqKey="Fan L" first="Linjun" last="Fan">Linjun Fan</name><name sortKey="Jiang, Jun" sort="Jiang, Jun" uniqKey="Jiang J" first="Jun" last="Jiang">Jun Jiang</name><name sortKey="Liang, Quankun" sort="Liang, Quankun" uniqKey="Liang Q" first="Quankun" last="Liang">Quankun Liang</name><name sortKey="Liu, Jing" sort="Liu, Jing" uniqKey="Liu J" first="Jing" last="Liu">Jing Liu</name><name sortKey="Ming, Jia" sort="Ming, Jia" uniqKey="Ming J" first="Jia" last="Ming">Jia Ming</name><name sortKey="Qi, Xiaowei" sort="Qi, Xiaowei" uniqKey="Qi X" first="Xiaowei" last="Qi">Xiaowei Qi</name><name sortKey="Zhong, Ling" sort="Zhong, Ling" uniqKey="Zhong L" first="Ling" last="Zhong">Ling Zhong</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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