LymphedemaV1, Ncbi, Checkpoint, bibRecord, 004561

Real-time in vivo imaging collagen in lymphedematous skin using multiphoton microscopy.

Identifieur interne : 004561 ( Ncbi/Checkpoint ); précédent : 004560; suivant : 004562

Real-time in vivo imaging collagen in lymphedematous skin using multiphoton microscopy.

Auteurs : Xiufeng Wu [République populaire de Chine] ; Shuangmu Zhuo ; Jianxin Chen ; Ningfei Liu

Source :

Scanning [ 1932-8745 ]

RBID : pubmed:21796645

Descripteurs français

KwdFr :
- Adénolymphome (anatomopathologie), Animaux, Collagène (analyse), Microscopie de fluorescence multiphotonique (), Rats, Souris, Tumeurs cutanées (anatomopathologie), Vidéomicroscopie ().
MESH :
- analyse : Collagène.
- anatomopathologie : Adénolymphome, Tumeurs cutanées.
- Animaux, Microscopie de fluorescence multiphotonique, Rats, Souris, Vidéomicroscopie.

English descriptors

KwdEn :
- Adenolymphoma (pathology), Animals, Collagen (analysis), Mice, Microscopy, Fluorescence, Multiphoton (methods), Microscopy, Video (methods), Rats, Skin Neoplasms (pathology).
MESH :
- chemical , analysis : Collagen.
- methods : Microscopy, Fluorescence, Multiphoton, Microscopy, Video.
- pathology : Adenolymphoma, Skin Neoplasms.
- Animals, Mice, Rats.

Abstract

Changes of dermal collagen are characteristic for chronic lymphedema. To evaluate these changes, a real-time imaging based on two-photon excited fluorescence and second-harmonic generation was developed for investigating collagen of lymphedematous mouse and rat tail skin in vivo. Our findings showed that the technique could image the morphological changes and distribution of collagen in lymphedematous mouse and rat tail skin in vivo. More importantly, it may allow visualization of dynamic collagen alteration during the progression of lymphedema. Our findings demonstrated that multiphoton microscopy may have potential in a clinical setting as an in vivo diagnostic and monitoring system for therapy in lymphology.

DOI: 10.1002/sca.20266
PubMed: 21796645

Affiliations:

République populaire de Chine

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pubmed:21796645

Le document en format XML

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<term>Microscopy, Fluorescence, Multiphoton (methods)</term>
<term>Microscopy, Video (methods)</term>
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<term>Souris</term>
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<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Adénolymphome</term>
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<front><div type="abstract" xml:lang="en">Changes of dermal collagen are characteristic for chronic lymphedema. To evaluate these changes, a real-time imaging based on two-photon excited fluorescence and second-harmonic generation was developed for investigating collagen of lymphedematous mouse and rat tail skin in vivo. Our findings showed that the technique could image the morphological changes and distribution of collagen in lymphedematous mouse and rat tail skin in vivo. More importantly, it may allow visualization of dynamic collagen alteration during the progression of lymphedema. Our findings demonstrated that multiphoton microscopy may have potential in a clinical setting as an in vivo diagnostic and monitoring system for therapy in lymphology.</div>
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<tree><noCountry><name sortKey="Chen, Jianxin" sort="Chen, Jianxin" uniqKey="Chen J" first="Jianxin" last="Chen">Jianxin Chen</name>
<name sortKey="Liu, Ningfei" sort="Liu, Ningfei" uniqKey="Liu N" first="Ningfei" last="Liu">Ningfei Liu</name>
<name sortKey="Zhuo, Shuangmu" sort="Zhuo, Shuangmu" uniqKey="Zhuo S" first="Shuangmu" last="Zhuo">Shuangmu Zhuo</name>
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<country name="République populaire de Chine"><noRegion><name sortKey="Wu, Xiufeng" sort="Wu, Xiufeng" uniqKey="Wu X" first="Xiufeng" last="Wu">Xiufeng Wu</name>
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Real-time in vivo imaging collagen in lymphedematous skin using multiphoton microscopy.

Real-time in vivo imaging collagen in lymphedematous skin using multiphoton microscopy.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki