Multipotent mesenchymal stem cells acquire a lymphendothelial phenotype and enhance lymphatic regeneration in vivo.
Identifieur interne : 003141 ( Ncbi/Checkpoint ); précédent : 003140; suivant : 003142Multipotent mesenchymal stem cells acquire a lymphendothelial phenotype and enhance lymphatic regeneration in vivo.
Auteurs : Claudius Conrad [États-Unis] ; Hanno Niess ; Ralf Huss ; Stephan Huber ; Irene Von Luettichau ; Peter J. Nelson ; Harald C. Ott ; Karl-Walter Jauch ; Christiane J. BrunsSource :
- Circulation [ 1524-4539 ] ; 2009.
Descripteurs français
- KwdFr :
- Animaux, Cellules souches multipotentes (cytologie), Cellules souches multipotentes (physiologie), Cellules stromales mésenchymateuses (cytologie), Cellules stromales mésenchymateuses (physiologie), Différenciation cellulaire (physiologie), Endothélium lymphatique (cytologie), Endothélium lymphatique (physiologie), Femelle, Humains, Lignée cellulaire, Lymphangiogenèse (physiologie), Mouvement cellulaire (physiologie), Phénotype, Régénération (physiologie), Souris, Souris de lignée BALB C, Souris de lignée C57BL, Vaisseaux lymphatiques (cytologie), Vaisseaux lymphatiques (physiologie).
- MESH :
- cytologie : Cellules souches multipotentes, Cellules stromales mésenchymateuses, Endothélium lymphatique, Vaisseaux lymphatiques.
- physiologie : Cellules souches multipotentes, Cellules stromales mésenchymateuses, Différenciation cellulaire, Endothélium lymphatique, Lymphangiogenèse, Mouvement cellulaire, Régénération, Vaisseaux lymphatiques.
- Animaux, Femelle, Humains, Lignée cellulaire, Phénotype, Souris, Souris de lignée BALB C, Souris de lignée C57BL.
English descriptors
- KwdEn :
- Animals, Cell Differentiation (physiology), Cell Line, Cell Movement (physiology), Endothelium, Lymphatic (cytology), Endothelium, Lymphatic (physiology), Female, Humans, Lymphangiogenesis (physiology), Lymphatic Vessels (cytology), Lymphatic Vessels (physiology), Mesenchymal Stromal Cells (cytology), Mesenchymal Stromal Cells (physiology), Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Multipotent Stem Cells (cytology), Multipotent Stem Cells (physiology), Phenotype, Regeneration (physiology).
- MESH :
- cytology : Endothelium, Lymphatic, Lymphatic Vessels, Mesenchymal Stromal Cells, Multipotent Stem Cells.
- physiology : Cell Differentiation, Cell Movement, Endothelium, Lymphatic, Lymphangiogenesis, Lymphatic Vessels, Mesenchymal Stromal Cells, Multipotent Stem Cells, Regeneration.
- Animals, Cell Line, Female, Humans, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Phenotype.
Abstract
The importance and therapeutic value of stem cells in lymphangiogenesis are poorly understood. We evaluated the potential of human and murine mesenchymal stem cells (MSCs) to acquire a lymphatic phenotype in vitro and to enhance lymphatic regeneration in vivo.
DOI: 10.1161/CIRCULATIONAHA.108.793208
PubMed: 19118255
Affiliations:
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pubmed:19118255Le document en format XML
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<affiliation wicri:level="2"><nlm:affiliation>Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. CConrad1@partners.org</nlm:affiliation>
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<author><name sortKey="Huss, Ralf" sort="Huss, Ralf" uniqKey="Huss R" first="Ralf" last="Huss">Ralf Huss</name>
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<author><name sortKey="Huber, Stephan" sort="Huber, Stephan" uniqKey="Huber S" first="Stephan" last="Huber">Stephan Huber</name>
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<author><name sortKey="Huber, Stephan" sort="Huber, Stephan" uniqKey="Huber S" first="Stephan" last="Huber">Stephan Huber</name>
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<author><name sortKey="Bruns, Christiane J" sort="Bruns, Christiane J" uniqKey="Bruns C" first="Christiane J" last="Bruns">Christiane J. Bruns</name>
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<series><title level="j">Circulation</title>
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<term>Cell Line</term>
<term>Cell Movement (physiology)</term>
<term>Endothelium, Lymphatic (cytology)</term>
<term>Endothelium, Lymphatic (physiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Lymphangiogenesis (physiology)</term>
<term>Lymphatic Vessels (cytology)</term>
<term>Lymphatic Vessels (physiology)</term>
<term>Mesenchymal Stromal Cells (cytology)</term>
<term>Mesenchymal Stromal Cells (physiology)</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
<term>Mice, Inbred C57BL</term>
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<term>Regeneration (physiology)</term>
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<term>Cellules souches multipotentes (cytologie)</term>
<term>Cellules souches multipotentes (physiologie)</term>
<term>Cellules stromales mésenchymateuses (cytologie)</term>
<term>Cellules stromales mésenchymateuses (physiologie)</term>
<term>Différenciation cellulaire (physiologie)</term>
<term>Endothélium lymphatique (cytologie)</term>
<term>Endothélium lymphatique (physiologie)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lignée cellulaire</term>
<term>Lymphangiogenèse (physiologie)</term>
<term>Mouvement cellulaire (physiologie)</term>
<term>Phénotype</term>
<term>Régénération (physiologie)</term>
<term>Souris</term>
<term>Souris de lignée BALB C</term>
<term>Souris de lignée C57BL</term>
<term>Vaisseaux lymphatiques (cytologie)</term>
<term>Vaisseaux lymphatiques (physiologie)</term>
</keywords>
<keywords scheme="MESH" qualifier="cytologie" xml:lang="fr"><term>Cellules souches multipotentes</term>
<term>Cellules stromales mésenchymateuses</term>
<term>Endothélium lymphatique</term>
<term>Vaisseaux lymphatiques</term>
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<term>Lymphatic Vessels</term>
<term>Mesenchymal Stromal Cells</term>
<term>Multipotent Stem Cells</term>
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<term>Endothélium lymphatique</term>
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<term>Régénération</term>
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<term>Endothelium, Lymphatic</term>
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<term>Lymphatic Vessels</term>
<term>Mesenchymal Stromal Cells</term>
<term>Multipotent Stem Cells</term>
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<term>Mice</term>
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<front><div type="abstract" xml:lang="en">The importance and therapeutic value of stem cells in lymphangiogenesis are poorly understood. We evaluated the potential of human and murine mesenchymal stem cells (MSCs) to acquire a lymphatic phenotype in vitro and to enhance lymphatic regeneration in vivo.</div>
</front>
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<name sortKey="Huss, Ralf" sort="Huss, Ralf" uniqKey="Huss R" first="Ralf" last="Huss">Ralf Huss</name>
<name sortKey="Jauch, Karl Walter" sort="Jauch, Karl Walter" uniqKey="Jauch K" first="Karl-Walter" last="Jauch">Karl-Walter Jauch</name>
<name sortKey="Nelson, Peter J" sort="Nelson, Peter J" uniqKey="Nelson P" first="Peter J" last="Nelson">Peter J. Nelson</name>
<name sortKey="Niess, Hanno" sort="Niess, Hanno" uniqKey="Niess H" first="Hanno" last="Niess">Hanno Niess</name>
<name sortKey="Ott, Harald C" sort="Ott, Harald C" uniqKey="Ott H" first="Harald C" last="Ott">Harald C. Ott</name>
<name sortKey="Von Luettichau, Irene" sort="Von Luettichau, Irene" uniqKey="Von Luettichau I" first="Irene" last="Von Luettichau">Irene Von Luettichau</name>
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