Unknown primary adenocarcinoma: incidence of overinvestigation and natural history.
Identifieur interne : 010C02 ( Main/Merge ); précédent : 010C01; suivant : 010C03Unknown primary adenocarcinoma: incidence of overinvestigation and natural history.
Auteurs : J F Stewart ; M H Tattersall ; R L Woods ; R M FoxSource :
- British Medical Journal [ 0007-1447 ] ; 1979.
Abstract
Out of 1300 patients referred to a medical oncology unit, there were 87 with metastatic cancer in whom a primary tumour site was not evident from the history and after physical examination and chest radiography had been carried out. An analysis of the investigations performed in these patients and their results showed that in only eight of the 87 patients did non-surgical investigations at presentation determine the primary site. In two patients it was identified by diagnostic laparotomy, and in a further 13 clinical follow-up led to recognition of the primary tumour site before death. Few investigations should be performed in patients in whom the primary site is known since they have a low yield, and in our population identifying the primary tumour did not improve the outcome or alter management. Treatable tumours should be excluded, and this may be done in most cases by simple blood tests, particularly those measuring acid phosphatase activity and other tumour markers.
Url:
PubMed: 466103
PubMed Central: 1599694
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 001616
- to stream Pmc, to step Curation: 001615
- to stream Pmc, to step Checkpoint: 004651
- to stream Ncbi, to step Merge: 009F60
- to stream Ncbi, to step Curation: 009F60
- to stream Ncbi, to step Checkpoint: 009F60
Links to Exploration step
PMC:1599694Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Unknown primary adenocarcinoma: incidence of overinvestigation and natural history.</title>
<author><name sortKey="Stewart, J F" sort="Stewart, J F" uniqKey="Stewart J" first="J F" last="Stewart">J F Stewart</name>
</author>
<author><name sortKey="Tattersall, M H" sort="Tattersall, M H" uniqKey="Tattersall M" first="M H" last="Tattersall">M H Tattersall</name>
</author>
<author><name sortKey="Woods, R L" sort="Woods, R L" uniqKey="Woods R" first="R L" last="Woods">R L Woods</name>
</author>
<author><name sortKey="Fox, R M" sort="Fox, R M" uniqKey="Fox R" first="R M" last="Fox">R M Fox</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">466103</idno>
<idno type="pmc">1599694</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1599694</idno>
<idno type="RBID">PMC:1599694</idno>
<date when="1979">1979</date>
<idno type="wicri:Area/Pmc/Corpus">001616</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001616</idno>
<idno type="wicri:Area/Pmc/Curation">001615</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001615</idno>
<idno type="wicri:Area/Pmc/Checkpoint">004651</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">004651</idno>
<idno type="wicri:Area/Ncbi/Merge">009F60</idno>
<idno type="wicri:Area/Ncbi/Curation">009F60</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">009F60</idno>
<idno type="wicri:doubleKey">0007-1447:1979:Stewart J:unknown:primary:adenocarcinoma</idno>
<idno type="wicri:Area/Main/Merge">010C02</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Unknown primary adenocarcinoma: incidence of overinvestigation and natural history.</title>
<author><name sortKey="Stewart, J F" sort="Stewart, J F" uniqKey="Stewart J" first="J F" last="Stewart">J F Stewart</name>
</author>
<author><name sortKey="Tattersall, M H" sort="Tattersall, M H" uniqKey="Tattersall M" first="M H" last="Tattersall">M H Tattersall</name>
</author>
<author><name sortKey="Woods, R L" sort="Woods, R L" uniqKey="Woods R" first="R L" last="Woods">R L Woods</name>
</author>
<author><name sortKey="Fox, R M" sort="Fox, R M" uniqKey="Fox R" first="R M" last="Fox">R M Fox</name>
</author>
</analytic>
<series><title level="j">British Medical Journal</title>
<idno type="ISSN">0007-1447</idno>
<imprint><date when="1979">1979</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Out of 1300 patients referred to a medical oncology unit, there were 87 with metastatic cancer in whom a primary tumour site was not evident from the history and after physical examination and chest radiography had been carried out. An analysis of the investigations performed in these patients and their results showed that in only eight of the 87 patients did non-surgical investigations at presentation determine the primary site. In two patients it was identified by diagnostic laparotomy, and in a further 13 clinical follow-up led to recognition of the primary tumour site before death. Few investigations should be performed in patients in whom the primary site is known since they have a low yield, and in our population identifying the primary tumour did not improve the outcome or alter management. Treatable tumours should be excluded, and this may be done in most cases by simple blood tests, particularly those measuring acid phosphatase activity and other tumour markers.</p>
</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 010C02 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 010C02 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Main |étape= Merge |type= RBID |clé= PMC:1599694 |texte= Unknown primary adenocarcinoma: incidence of overinvestigation and natural history. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i -Sk "pubmed:466103" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd \ | NlmPubMed2Wicri -a LymphedemaV1
This area was generated with Dilib version V0.6.31. |