Prophylactic lymphadenectomy vs observation vs inguinal biopsy in node-negative patients with invasive carcinoma of the penis.
Identifieur interne : 00D625 ( Main/Merge ); précédent : 00D624; suivant : 00D626Prophylactic lymphadenectomy vs observation vs inguinal biopsy in node-negative patients with invasive carcinoma of the penis.
Auteurs : R. Ravi [Inde]Source :
- Japanese journal of clinical oncology [ 0368-2811 ] ; 1993.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Aine, Biopsie, Humains, Lymphadénectomie, Mâle, Métastase lymphatique (diagnostic), Noeuds lymphatiques (anatomopathologie), Sujet âgé, Sujet âgé de 80 ans ou plus, Taux de survie, Tumeurs du pénis (), Tumeurs du pénis (anatomopathologie), Tumeurs du pénis (mortalité), Études rétrospectives.
- MESH :
- anatomopathologie : Noeuds lymphatiques, Tumeurs du pénis.
- diagnostic : Métastase lymphatique.
- mortalité : Tumeurs du pénis.
- Adulte, Adulte d'âge moyen, Aine, Biopsie, Humains, Lymphadénectomie, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Taux de survie, Tumeurs du pénis, Études rétrospectives.
English descriptors
- KwdEn :
- MESH :
- diagnosis : Lymphatic Metastasis.
- mortality : Penile Neoplasms.
- pathology : Lymph Nodes, Penile Neoplasms.
- surgery : Penile Neoplasms.
- Adult, Aged, Aged, 80 and over, Biopsy, Groin, Humans, Lymph Node Excision, Male, Middle Aged, Retrospective Studies, Survival Rate.
Abstract
From 1962 to 1984, 423 patients with invasive penile cancer and negative groin nodes were subjected to prophylactic lymphadenectomies (n113), observations (n258) or inguinal biopsies (n52) in a non-randomised fashion. The numbers of patients with T2, T3 and T4 lesions were similar in the three groups. The overall five-year disease-free survivals were 94, 93 and 85%, respectively. All groin recurrences in the observation group occurred within 18 months of the surgery for the primary tumor. The five-year disease-free survivals of node-positive patients in the lymphadenectomy and observation groups were 100 and 76%, respectively; three patients in the latter group had refused surgical treatment when their adenopathy was mobile. Morbidity from the prophylactic lymphadenectomies included wound breakdown in 61%, wound infection in 18% and lymphedema in 25% of patients. We feel that neither prophylactic lymphadenectomy nor inguinal biopsy are justified in these patients. Close observation of the groin nodal status would be appropriate.
PubMed: 8459642
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Ravi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genitourinary Surgery, Cancer Institute (WIA), Madras, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Genitourinary Surgery, Cancer Institute (WIA), Madras</wicri:regionArea><wicri:noRegion>Madras</wicri:noRegion></affiliation></author></analytic><series><title level="j">Japanese journal of clinical oncology</title><idno type="ISSN">0368-2811</idno><imprint><date when="1993" type="published">1993</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Biopsy</term><term>Groin</term><term>Humans</term><term>Lymph Node Excision</term><term>Lymph Nodes (pathology)</term><term>Lymphatic Metastasis (diagnosis)</term><term>Male</term><term>Middle Aged</term><term>Penile Neoplasms (mortality)</term><term>Penile Neoplasms (pathology)</term><term>Penile Neoplasms (surgery)</term><term>Retrospective Studies</term><term>Survival Rate</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Aine</term><term>Biopsie</term><term>Humains</term><term>Lymphadénectomie</term><term>Mâle</term><term>Métastase lymphatique (diagnostic)</term><term>Noeuds lymphatiques (anatomopathologie)</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Taux de survie</term><term>Tumeurs du pénis ()</term><term>Tumeurs du pénis (anatomopathologie)</term><term>Tumeurs du pénis (mortalité)</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Noeuds lymphatiques</term><term>Tumeurs du pénis</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Lymphatic Metastasis</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Métastase lymphatique</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Penile Neoplasms</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Tumeurs du pénis</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lymph Nodes</term><term>Penile Neoplasms</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Penile Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Biopsy</term><term>Groin</term><term>Humans</term><term>Lymph Node Excision</term><term>Male</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Survival Rate</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Aine</term><term>Biopsie</term><term>Humains</term><term>Lymphadénectomie</term><term>Mâle</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Taux de survie</term><term>Tumeurs du pénis</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">From 1962 to 1984, 423 patients with invasive penile cancer and negative groin nodes were subjected to prophylactic lymphadenectomies (n113), observations (n258) or inguinal biopsies (n52) in a non-randomised fashion. The numbers of patients with T2, T3 and T4 lesions were similar in the three groups. The overall five-year disease-free survivals were 94, 93 and 85%, respectively. All groin recurrences in the observation group occurred within 18 months of the surgery for the primary tumor. The five-year disease-free survivals of node-positive patients in the lymphadenectomy and observation groups were 100 and 76%, respectively; three patients in the latter group had refused surgical treatment when their adenopathy was mobile. Morbidity from the prophylactic lymphadenectomies included wound breakdown in 61%, wound infection in 18% and lymphedema in 25% of patients. We feel that neither prophylactic lymphadenectomy nor inguinal biopsy are justified in these patients. Close observation of the groin nodal status would be appropriate.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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