The influence of local hyperthermia on lymphedema and lymphedematous skin of the human leg.
Identifieur interne : 00D599 ( Main/Merge ); précédent : 00D598; suivant : 00D600The influence of local hyperthermia on lymphedema and lymphedematous skin of the human leg.
Auteurs : N F Liu [République populaire de Chine] ; W. OlszewskiSource :
- Lymphology [ 0024-7766 ] ; 1993.
Descripteurs français
- KwdFr :
- MESH :
- anatomopathologie : Lymphoedème, Peau, Système lymphatique.
- imagerie diagnostique : Lymphoedème.
- Humains, Hyperthermie provoquée, Jambe, Lymphoedème, Lymphoscintigraphie, Technétium.
English descriptors
- KwdEn :
- MESH :
- chemical : Technetium.
- diagnostic imaging : Lymphedema.
- pathology : Lymphatic System, Lymphedema, Skin.
- therapy : Lymphedema.
- Humans, Hyperthermia, Induced, Leg, Lymphoscintigraphy.
Abstract
The influence of microwave and hot water immersion hyperthermia on lymphedema and lymphedematous skin of the leg in 12 patients was studied using circumference and volumetric measurements, immunohistochemistry and "quantitative" lymphoscintigraphy. Whereas heating was associated with a reduction in the girth and volume of the leg, lymph flow as assessed by lymphoscintigraphy was unchanged. Neither absorption of the radiolabeled nanocolloid from the injection site nor the rate of tracer accumulation in the inguinal lymph nodes was significantly altered by heat therapy. Histologically, the lymphedematous skin after heat treatment showed near resolution of perivascular cellular infiltration, disappearance of "lymph lakes" and dilatation of blood capillaries. Labeling of skin migrating immune cells with monoclonal antibodies confirmed subsidence of dermal cellular infiltration; nonetheless, there was nonspecific stimulation of resident epidermal immune cells, endothelial cells, macrophages, lymphocytes and keratinocytes by intense expression of class II and other antigens. There seemed to be a direct relationship between the subsidence of dermal inflammation and a decrease in leg edema. We suspect that subsidence of local inflammation in the lymphedematous limb with alteration in the extracellular protein matrix after regional heating accounts for the reduction in peripheral edema.
PubMed: 8464223
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 005765
- to stream PubMed, to step Curation: 005765
- to stream PubMed, to step Checkpoint: 005765
- to stream Ncbi, to step Merge: 00B601
- to stream Ncbi, to step Curation: 00B601
- to stream Ncbi, to step Checkpoint: 00B601
Links to Exploration step
pubmed:8464223Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The influence of local hyperthermia on lymphedema and lymphedematous skin of the human leg.</title>
<author><name sortKey="Liu, N F" sort="Liu, N F" uniqKey="Liu N" first="N F" last="Liu">N F Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>Shanghai Institute of Plastic Surgery, Shanghai Second Medical University, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Shanghai Institute of Plastic Surgery, Shanghai Second Medical University</wicri:regionArea>
<wicri:noRegion>Shanghai Second Medical University</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Olszewski, W" sort="Olszewski, W" uniqKey="Olszewski W" first="W" last="Olszewski">W. Olszewski</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1993">1993</date>
<idno type="RBID">pubmed:8464223</idno>
<idno type="pmid">8464223</idno>
<idno type="wicri:Area/PubMed/Corpus">005765</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">005765</idno>
<idno type="wicri:Area/PubMed/Curation">005765</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">005765</idno>
<idno type="wicri:Area/PubMed/Checkpoint">005765</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">005765</idno>
<idno type="wicri:Area/Ncbi/Merge">00B601</idno>
<idno type="wicri:Area/Ncbi/Curation">00B601</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">00B601</idno>
<idno type="wicri:doubleKey">0024-7766:1993:Liu N:the:influence:of</idno>
<idno type="wicri:Area/Main/Merge">00D599</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">The influence of local hyperthermia on lymphedema and lymphedematous skin of the human leg.</title>
<author><name sortKey="Liu, N F" sort="Liu, N F" uniqKey="Liu N" first="N F" last="Liu">N F Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>Shanghai Institute of Plastic Surgery, Shanghai Second Medical University, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Shanghai Institute of Plastic Surgery, Shanghai Second Medical University</wicri:regionArea>
<wicri:noRegion>Shanghai Second Medical University</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Olszewski, W" sort="Olszewski, W" uniqKey="Olszewski W" first="W" last="Olszewski">W. Olszewski</name>
</author>
</analytic>
<series><title level="j">Lymphology</title>
<idno type="ISSN">0024-7766</idno>
<imprint><date when="1993" type="published">1993</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Humans</term>
<term>Hyperthermia, Induced</term>
<term>Leg</term>
<term>Lymphatic System (pathology)</term>
<term>Lymphedema (diagnostic imaging)</term>
<term>Lymphedema (pathology)</term>
<term>Lymphedema (therapy)</term>
<term>Lymphoscintigraphy</term>
<term>Skin (pathology)</term>
<term>Technetium</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Humains</term>
<term>Hyperthermie provoquée</term>
<term>Jambe</term>
<term>Lymphoedème ()</term>
<term>Lymphoedème (anatomopathologie)</term>
<term>Lymphoedème (imagerie diagnostique)</term>
<term>Lymphoscintigraphie</term>
<term>Peau (anatomopathologie)</term>
<term>Système lymphatique (anatomopathologie)</term>
<term>Technétium</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Technetium</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Lymphoedème</term>
<term>Peau</term>
<term>Système lymphatique</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Lymphoedème</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lymphatic System</term>
<term>Lymphedema</term>
<term>Skin</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
<term>Hyperthermia, Induced</term>
<term>Leg</term>
<term>Lymphoscintigraphy</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Humains</term>
<term>Hyperthermie provoquée</term>
<term>Jambe</term>
<term>Lymphoedème</term>
<term>Lymphoscintigraphie</term>
<term>Technétium</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The influence of microwave and hot water immersion hyperthermia on lymphedema and lymphedematous skin of the leg in 12 patients was studied using circumference and volumetric measurements, immunohistochemistry and "quantitative" lymphoscintigraphy. Whereas heating was associated with a reduction in the girth and volume of the leg, lymph flow as assessed by lymphoscintigraphy was unchanged. Neither absorption of the radiolabeled nanocolloid from the injection site nor the rate of tracer accumulation in the inguinal lymph nodes was significantly altered by heat therapy. Histologically, the lymphedematous skin after heat treatment showed near resolution of perivascular cellular infiltration, disappearance of "lymph lakes" and dilatation of blood capillaries. Labeling of skin migrating immune cells with monoclonal antibodies confirmed subsidence of dermal cellular infiltration; nonetheless, there was nonspecific stimulation of resident epidermal immune cells, endothelial cells, macrophages, lymphocytes and keratinocytes by intense expression of class II and other antigens. There seemed to be a direct relationship between the subsidence of dermal inflammation and a decrease in leg edema. We suspect that subsidence of local inflammation in the lymphedematous limb with alteration in the extracellular protein matrix after regional heating accounts for the reduction in peripheral edema.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00D599 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 00D599 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Main |étape= Merge |type= RBID |clé= pubmed:8464223 |texte= The influence of local hyperthermia on lymphedema and lymphedematous skin of the human leg. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i -Sk "pubmed:8464223" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd \ | NlmPubMed2Wicri -a LymphedemaV1
This area was generated with Dilib version V0.6.31. |